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Introduction
Jose M Arribas currently works at the Departamento de Cirugía Cardiovascular, Hospital Universitario Virgen de la Arrixaca. Jose does research in Cardiothoracic Surgery and Cardiology.
Current institution
Additional affiliations
January 2006 - present
Publications
Publications (103)
Background
Several aspects of the occurrence and management of mycotic aneurysm (MA) in patients with infective endocarditis (IE) have not been studied.
Objectives
To determine the incidence and factors associated with MA presence and rupture and to assess the evolution of those initially unruptured MA.
Methods
Prospective multicenter cohort incl...
Objective
Post-operative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery, increasing the morbidity and mortality of this specific patient population. We investigated the association of clinical, biochemical and molecular markers on several tissues with the occurrence of POAF in patients undergoing coronary and/or valv...
Background
Rapid deployment aortic valve replacement (RD-AVR) has been recently introduced with encouraging results. Outcomes of isolated RD-AVR include good hemodynamic profile, facilitation of minimally invasive techniques, and reduction of surgical times. However, role of this prosthesis in concomitant surgery is not well known.
Methods
In 2016...
Background
Glucagon is thought to increase heart rate and contractility by stimulating glucagon receptors and increasing 3′,5′-cyclic adenosine monophosphate (cAMP) production in the myocardium. This has been confirmed in animal studies but not in the human heart. The cardiostimulatory effects of glucagon have been correlated with the degree of car...
Obstructive sleep apnea (OSA) promotes atrial remodeling and fibrosis, providing a substrate for atrial fibrillation (AF). Herein, we investigate the pathophysiological mechanisms of AF in association with OSA in a cohort of cardiac surgery patients. A prospective study including patients undergoing cardiac surgery. Biomarkers reflective of AF path...
Background: New era of cardiac surgery aims to provide an enhanced postoperative recovery by the implementation of every step of the process. Thus, perfusion strategy should adopt evidence-based measures to reduce the impact of cardiopulmonary bypass (CPB). Hematic Antegrade Repriming (HAR) provides a standardized procedure combining several measur...
Experience with rapid deployment aortic valve replacement with
concomitant cardiac procedure
Introduction
Historically, the definition of valvular heart disease in atrial fibrillation (AF) patients has been inconsistent. For this reason, in 2017 the EHRA proposed a more accurate classification, classifing AF patients in EHRA I (AF patients with mechanical prostheses or moderate/severe rheumatic mitral stenosis), EHRA II (includes the prese...
Introduction
The development of post-operative atrial fibrillation (POAF) after cardiac surgeryis associated with pre-existing endothelial activation and systemic inflammation due to adhesion and transmigration of leukocytes into the interstitium. The electrical remodelling associated with AF causes changes in connexins, resulting in ineffective el...
Sternal surgical wound infection (SSWI) in cardiac surgery is associated with increased morbidity. We investigated the incidence of SSWI, the main germs implicated and predictors of SSWI. Prospective study including patients undergoing full median sternotomy between January 2017 and December 2019. Patients were followed-up for 3 months after hospit...
Particulate and gaseous microemboli (GME) are side effects of cardiac surgery that interfere with postoperative recovery by causing endothelial dysfunction and vascular blockages. GME sources during surgery are multiple, and cardiopulmonary bypass (CPB) is contributory to this embolic load. Hematic antegrade repriming (HAR) is a novel procedure tha...
Introduction
Accessory left atrial cords are fibroelastic structures found in the left atrium. Left atrial cords may be associated with mitral valve disease, atrial fibrillation, stroke, and other congenital left‐side anomalies.
Methods
We presented the case of a man with severe Mitral Regurgitation and two accessories left atrial cords attached t...
OBJECTIVES
We report on real-world safety and performance outcomes of minimally invasive rapid-deployment aortic valve replacement using the EDWARDS INTUITY Elite aortic valve system.
METHODS
The study valve system was used in a European, prospective, multicentre post-market study. Various procedural, haemodynamic and clinical outcomes were evalua...
RESUMEN
Introducción y objetivos: la oxigenación con membrana extracorpórea (ECMO) ha resultado ser una opción terapéutica en los pacientes con insuficiencia respiratoria y/o cardiaca severa por COVID-19. Las indicaciones y manejo de estos pacientes están aún por determinar. Nuestro objetivo es evaluar los resultados de la terapia ECMO en pacientes...
Background:
The use of rapid deployment and sutureless aortic prostheses is increasing. Previous reports have shown promising results on haemodynamic performance and mortality rates. However, the impact of these bioprostheses on left ventricular mass (LVM) regression remains unknown. We decided to study the changes in remodelling and LVM regressio...
OBJECTIVES
The Edwards Intuity valve is a rapid deployment aortic prosthesis that favours less invasive approaches. However, evidence about the clinical behaviour of their smaller sizes is scarce. Herein, we studied haemodynamic behaviours and clinical outcomes of small Intuity prostheses (19–21 mm) in comparison to larger Intuity prostheses (>21 m...
Objective: The Edwards Intuity valve is a rapid deployment biological aortic prosthesis. It is another option to treat aortic stenosis. It favors less aggressive approaches and shortens surgical times. Little is known about the hemodynamic and clinical behavior of their smaller sizes. We present our experience with Intuity prostheses Nos. 19 and 21...
Objective: Severe pulmonary hypertension is a poor prognostic factor in cardiac surgery. However, advances in surgery, anesthesia and postoperative care, as well as a better understanding of the pathophysiology of pulmonary hypertension, make it possible to offer surgery to more patients in this situation. We present a series of consecutive heart-o...
Objectives: Rapid deployment Aortic valves have become an alternative for aortic valve stenosis treatment in recent years. Edwards Intuity was developed over Perimount Edwards Magna Ease design, with the addition of an infraannular ballon-expandable frame. So, we could hypothesize that outcomes should be similar between both protheses. Very few stu...
Objective: Rapid deployment aortic valves appeared ten years ago to treat aortic stenosis. The Edwards Intuity Valve System is a biological prosthesis based on the Edwards Magna valve with an infra-annular framework. We present the short and intermediate-term clinical and hemodynamic results obtained with this biological prosthesis.
Methods: One hu...
Objective: Upper hemisternotomy in aortic valve surgery has been used for 20 years. Rapid deployment aortic prostheses facilitate the use of less invasive approaches and shorten surgical times. Our objective is to compare a series of patients who received the Edwards Intuity Rapid Deployment Aortic Prosthesis via hemisternotomy or full sternotomy....
The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable to eliminate all microbubbles contained in the circuit. In addition, it causes a sudden hemodilution which is correlated with transfusi...
IntroductionRapid deployment aortic valve replacement has been recently introduced in clinical practice. Different studies have reported a significant reduction in surgical times with excellent hemodynamic profiles and short-term results. However, an increase in permanent pacemaker requirements compared with conventional aortic valve replacement ha...
The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable to eliminate all microbubbles contained in the circuit. In addition, it causes a sudden hemodi-lution which is correlated with transfus...
Objective
To investigate the rate of colorectal neoplasms (CRNs) in patients who have Enterococcus faecalis infective endocarditis (EFIE) with available colonoscopies and to assess whether this is associated with the identification of a focus the infection.
Patients and Methods
Retrospective analysis of data from a prospective multicenter study in...
Background
Durability of bioprosthesis in pulmonary position in patients with congenital heart disease remains suboptimal. The new INSPIRIS Resilia aortic valve is characterized by a pericardial tissue which could improve hemodynamic performance and durability. The aim of our study is to report the initial experience with this valve in pulmonary po...
Resumen
Introducción
Las prótesis aorticas de rápido despliegue aparecieron hace 10 años para tratar la estenosis aórtica. El sistema de válvula Edwards Intuity es una prótesis biológica basada en la válvula Edwards Magna con un marco infraanular. Presentamos los resultados clínicos y hemodinámicos a corto y largo plazo obtenidos con esta prótesis...
Objective: We studied patients who had experienced a stroke in the postoperative period of cardiac surgery, aiming to analyse their progression and determine the factors that may influence prognosis and treatment. Methods: We established a protocol for early detection of stroke after cardiac surgery and collected data on stroke onset and a number o...
BACKGROUND Enterococcal endocarditis (EE) is a growing entity in Western countries. However, quality data from
large studies is lacking.
OBJECTIVES The purpose of this study was to describe the characteristics and analyze the prognostic factors of EE in
the GAMES cohort.
METHODS This was a post hoc analysis of a prospectively collected cohort of pa...
Background:
Aortic stenosis is currently the most frequently occurring valve pathology. Developments such as transcatheter prostheses and rapid deployment prostheses allow for the offer of a valve replacement to higher risk patients, but these techniques are linked with a higher need for a permanent pacemaker during the immediate postoperative per...
Objective
We studied patients who had experienced a stroke in the postoperative period of cardiac surgery, aiming to analyse their progression and determine the factors that may influence prognosis and treatment.
Methods
We established a protocol for early detection of stroke after cardiac surgery and collected data on stroke onset and a number of...
Resumen: Introducción y objetivos: El cierre quirúrgico del ductus arterioso persistente (DAP) en prematuros provoca un cambio en el sistema circulatorio que afecta al miocardio inmaduro de estos pacientes. El objetivo del estudio fue analizar la respuesta del ventrículo izquierdo al cierre del DAP, basándonos en parametros ecocardiográficos pre- y...
Resumen: La cirugía cardiovascular es la especialidad médica que se ocupa de la prevención, diagnóstico y tratamiento quirúrgico de los trastornos y enfermedades del sistema cardiocirculatorio. Los continuos y rápidos avances en el diagnóstico y tratamiento de las enfermedades cardiovasculares justifican la necesidad de llevar a cabo una actualizac...
Purpose:
The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality.
Methods:
Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratifie...
Background:
There is little information concerning infective endocarditis (IE) in patients with bicuspid aortic valve (BAV) or mitral valve prolapse (MVP). Currently, IE antibiotic prophylaxis (IEAP) is not recommended for these conditions.
Objectives:
This study sought to describe the clinical and microbiological features of IE in patients with...
Purpose:
To analyze the influence of adding gentamicin to a regimen consisting of β-lactam or vancomycin plus rifampicin on survival in patients suffering from Staphylococcal prosthetic valve endocarditis (SPVE).
Methods:
From January 2008 to September 2016, 334 patients with definite SPVE were attended in the participating hospitals. Ninety-fou...
Objective:
We studied patients who had experienced a stroke in the postoperative period of cardiac surgery, aiming to analyse their progression and determine the factors that may influence prognosis and treatment.
Methods:
We established a protocol for early detection of stroke after cardiac surgery and collected data on stroke onset and a numbe...
Objective
Goals of rapid deployment aortic valve replacement (RDAVR) include facilitation of minimally invasive surgery and reduced aortic cross clamp time (XCT). Herein we report short-term outcomes of a series of 493 patients undergoing RDAVR with the EDWARDS INTUITY valve system.
Methods
FOUNDATION was a prospective, multicenter (n = 26) Europe...
Introducción y objetivos: El ductus arterioso persistente es un problema frecuente en prematuros. El cierre quirúrgico es una opción terapéutica. El objetivo del estudio es determinar los factores de riesgo relacionados con mortalidad hospitalaria y analizar la utilidad de la escala Aristóteles como predictor de la misma.
Método: Análisis retrospec...
Introduction
Rapid deployment valves (RDV) represent a newly introduced approach to aortic valve replacement which facilitates surgical implantation and minimally invasive techniques, shortens surgical times and shows excellent haemodynamic performance. However, evidence on their safety, efficacy and potential complications is mostly fitted with sm...
The present article represents the first official report of Spanish Registry for Mechanical Circulatory Support (ESPAMACS) and summarizes the registry activity since it began operating in October 2014 to May 2016. Along this period, 369 mechanical circulatory support devices implanted at 18 different centers of our country have been registered: 319...
Aims:
Atrial fibrillation (AF) is associated with an increased morbidity and mortality after cardiac surgery. Von Willebrand factor (vWF) has been proposed as a biomarker of endothelial damage/dysfunction. We hypothesized that vWF levels could be used as valuable biomarker for AF occurrence after cardiac surgery. Moreover, we explored the potentia...
Objetivo: Disponemos de una nueva clase de prótesis aórticas de despliegue rápido para tratamiento quirúrgico de la estenosis aórtica. Permitirían disminuir los tiempos quirúrgicos y facilitarían la cirugía mínimamente invasiva. Presentamos nuestra experiencia inicial con la válvula Edwards Intuity en el contexto del estudio multicéntrico Foundatio...
Ellis-van Creveld (EvC) syndrome is a rare autosomal recessive malformation disorder. Cardiac defects are observed in about 50% of EvC cases. Surgical data is lacking on the prognosis and life expectancy of EvC patients. Herein, we report the case of a 38-year-old man with EvC syndrome who underwent two surgical corrections for cardiac anomalies. T...
Atrial fibrillation (AF) has an incidence rate of approximately 30% and is the most frequent arrhythmia following heart surgery. Factors such as inflammation, the presence of heart fibrosis, stress and cardiomyocyte apoptosis, have all been associated with AF.
We believe that atrial remodelling is a pre-existent process in patients with post-surgic...
Introduction
Cardiac myxoma is an important but uncommon cause of stroke in younger patients. Few published case series analyse the frequency and clinical presentation of neurological complications in patients with myxoma.
Objective
To list all neurological complications from cardiac myxoma recorded in our hospital in the past 28 years.
Patients...
Atrial fibrillation (AF) occurs in ∼30% of patients undergoing coronary artery bypass grafting (CABG) and in 40% of patients after valve surgery. High-sensitivity cardiac troponin T (hsTnT) is a specific and high-sensitivity marker of myocardial injury, while N-terminal proB-type natriuretic peptide (NT-proBNP) is an established biomarker for wall...
The safety and efficacy of temporary epicardial pacing wires have been accepted and their use is common after cardiac procedures. Complications related after wire removal are unusual but it can be serious including bleeding, tamponade and death.
We report an unusual case of a 48-year-old-male who underwent to a coronary artery bypass grafting proce...
Chyloperitoneum is a rare but life-threatening complication with no uniformity concerning the treatment. We present a 77-year-old male with chylous ascites after open abdominal aneurysmectomy refractory to conservative and surgical strategies. After failure of re-exploration with periaortic lymphatic cauterization and drainage, he was treated with...
Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with an increased morbimortality after cardiac surgery and a higher hospital length of stay; and occurs in approximately 30% of patients. High sensitive cardiac troponin T (hsTnT) is a specific and high-sensitivity marker of myocardial injury. Our hypothesis is that...
Introduction:
Cardiac myxoma is an important but uncommon cause of stroke in younger patients. Few published case series analyse the frequency and clinical presentation of neurological complications in patients with myxoma.
Objective:
To list all neurological complications from cardiac myxoma recorded in our hospital in the past 28 years.
Patie...
Introducción
En los tiempos actuales la tendencia en la cirugía cardíaca es a realizar procedimientos menos agresivos, en ocasiones demandados por los pacientes. Por este motivo decidimos iniciar el programa de cirugía aórtica por miniesternotomía.
Material y métodos
Desde enero de 2010 - enero de 2012 hemos operado a 20 pacientes de sustitución v...
Introducción
El uso de marcapasos epicárdicos transitorios tras cirugía de revascularización miocárdica es una práctica habitual en muchos centros por su seguridad y eficacia. Las complicaciones relacionadas tras la retirada de los mismos son inusuales pero graves, incluyendo hemorragia, taponamiento y muerte.
Material y métodos
Describimos el cas...
Introducción
Las válvulas aórticas biológicas sin soporte Sorin Freedom Solo (FS) han demostrado una mejoría en el aumento del orificio de área efectivo, así como un mejor perfil en los gradientes transvalvulares, fracción de eyección del ventrículo izquierdo (FEVI) y regresión de la hipertrofia ventricular izquierda. También, se ha comprobado una...
La circulación extracorpórea y el tiempo de isquemia prolongados pueden aumentar la morbimortalidad en la cirugía de recambio valvular aórtico, especialmente en pacientes añosos y de alto riesgo quirúrgico. El uso de prótesis autoexpandibles acorta significativamente estos tiempos y ofrece ventajas quirúrgicas.
Material y métodos: De abril-diciembr...
Introducción y objetivos
Desde 2006 se dispone de la vía de implante percutánea para las prótesis valvulares aórticas. Por el momento esta vía percutánea se ha reservado para pacientes de alto riesgo con la cirugía con circulación extracorpórea (CEC). Presentamos la experiencia inicial en nuestro hospital con prótesis aórtica percutánea vía transfe...
La transfusión de concentrados de hematíes (CH) en cirugía de revascularización miocárdica (CRM) primaria se asocia a complicaciones y varía mucho entre centros. Ciertas características de los pacientes podrían predecir la transfusión de CH en CRM. Diseñamos un estudio para conocer las variables clínicas asociadas a transfusión de CH en CRM primari...
The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established.
The study involved 203 consecutive patients (age 64+/-9 years, 74% male) scheduled for elective coronary surgery. The maximum QRS durati...
Introduction and objectives
The duration of the QRS interval measured by ECG is a marker of ventricular dysfunction and indicates a poor prognosis. Its value in patients undergoing coronary revascularization surgery has not been established.
Methods
The study involved 203 consecutive patients (age 64±9 years, 74% male) scheduled for elective coron...
Low-output syndrome is one of the leading causes of death following open-heart surgery or high-risk angioplasty. Ventricular assist devices have been used to treat patients who suffer from postoperative cardiogenic shock despite use of an intraaortic balloon pump and maximum inotropic support. The Impella pump (Impella Cardiosystems AG, Aachen, Ger...
Low-output syndrome is one of the leading causes of death following open-heart surgery or high-risk angioplasty. Ventricular assist devices have been used to treat patients who suffer from postoperative cardiogenic shock despite use of an intraaortic balloon pump and maximum inotropic support. The Impella pump (Impella Cardiosystems AG, Aachen, Ger...
Postoperative atrial fibrillation (PAF) is a frequent complication of coronary artery bypass grafting (CABG). Our aims were to study its epidemiology and to identify predictors in everyday clinical practice, while taking into account statin use, extracorporeal circulation, and new biomarkers of inflammation and ventricular stress.
The study include...
Introduction and objectives
Postoperative atrial fibrillation (PAF) is a frequent complication of coronary artery bypass grafting (CABG). Our aims were to study its epidemiology and to identify predictors in everyday clinical practice, while taking into account statin use, extracorporeal circulation, and new biomarkers of inflammation and ventricul...
This case report shows the use of bedside transthoracic contrast echocardiography in the diagnosis of subacute myocardial rupture after acute myocardial infarction and indication of urgent surgery. Usefulness of intraoperative transesophageal echocardiography for detection of sudden complete myocardial rupture leading to pericardial tamponade durin...
Introduction
The aim of the study is to report our initial experience with combined open surgical treatment and endovascular therapy in the treatment of complex thoracic aortic disease.
Material and methods
Two patients treated with similar surgical strategy including surgical revascularization of the neck vessels and deployment of thoracic aortic...
The value of biomarkers of myocardial damage or inflammation in off-pump coronary artery bypass (OPCAB) surgery has not yet been established. In a prospective study of 51 consecutive patients scheduled for elective OPCAB surgery, preoperative levels of troponin T, C-reactive protein, interleukin-6 and tumor necrosis factor-α were determined. The pr...
The value of biomarkers of myocardial damage or inflammation in off-pump coronary artery bypass (OPCAB) surgery has not yet been established. In a prospective study of 51 consecutive patients scheduled for elective OPCAB surgery, preoperative levels of troponin T, C-reactive protein, interleukin-6 and tumor necrosis factor-alpha were determined. Th...
Atrial fibrillation (AF) is a common complication after coronary artery bypass grafting. Atrial remodeling has been observed in AF and has been associated with the development of this arrhythmia. Because 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) have been demonstrated to modify remodeling, we hypothesized a protective role of stati...
Pretreatment with statins reduces early ischemic events after percutaneous coronary interventions, primarily in patients with a high level of inflammation markers. We sought to examine the association between preoperative statin therapy, systemic inflammation, and myocardial ischemia with the occurrence of early cardiac complications after coronary...
Presentamos la experiencia inicial con la canulación de la arteria axilar en su tercera porción extratorácica en la raíz del brazo derecho o hueco axilar. De diciembre de 2003 a mayo de 2004, hemos intervenido cuatro pacientes con enfermedad de aorta ascendente en los cuales hemos colocado la cánula de retorno arterial de la circulación extracorpór...
Introduction
Statin treatment diminishes adverse cardiac events both in primary and secondary prevention and also after percutaneous coronary intervention.
Objective
To study if preoperative statin treatment is associated with any clinical advantage after coronary artery surgery.
Methods
We enrolled 102 consecutive patients with coronary artery d...
Q fever is characterized by its clinical polymorphism. Cardiac involvement in acute Q fever is rare. We report a case of pleuro-pericarditis that rapidly evolved to pericardial constriction during an acute episode of Coxiella burnetii infection. Constrictive pericarditis was confirmed by hemodynamic measurements, echocardiography, and magnetic reso...
Purpose
To report endovascular repair of dual aneurysms in a patient with Behçet's disease.
Case Report
A 37-year-old man diagnosed 6 months prior with Behçet's disease presented with a pulsating abdominal mass. Computed tomography revealed a 70-mm-diameter pseudoaneurysm in the abdominal aorta and another (20 mm) in the celiac trunk 5 mm from the...
We present a successful use of biventricular pneumatic assistance during seven days allowing the recovery from a severe primary graft failure that occurred in the operating room. Suboptimal donors are associated with higher rates of immediate graft failure; however proper use of mechanical assistance can help to recover graft function.
Introdução
As fístulas arteriovenosas de apresentação espontânea constituem uma patologia vascular pouco frequente.
Caso clínico
Homem de 44 anos de idade, trabalhador da construção civil, sem antecedentes traumáticos, apresenta um tumor pulsátil no pulso esquerdo. Um estudo com eco-Doppler evidencia a existência de uma fístula arteriovenosa da ar...
Introduction. Spontaneously appearing arteriovenous fistulae are an infrequent pathological condition. Case report. We report the case ofa 44-year-old male, employed as a builder, with no history of traumatic injury, who presented a pulsating tumour in his left wrist. A Doppler ultrasound study revealed the existence of an arteriovenous fistula in...
Mitral surgery is tradicionally done using aortic cross-clampping and different cardioplejic solutions to protect the heart during the cross-clampping time. It permits to operate in a bloodness field and in an arrested heart. Moreover aortic cross-clampping is related with neurological disorders after cardiac surgery. For all these reasons we think...
The present study reviews our experience with the ATS Medical valve in a series of patients who underwent reoperations at our institution for a variety of causes.