Jose Andres Calvache

Jose Andres Calvache
Universidad del Cauca · Departamento de Anestesiología

MD MSc PhD

About

177
Publications
106,757
Reads
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1,320
Citations
Introduction
I work at the Departamento de Anestesiología, Universidad del Cauca, Colombia and also as associate researcher at Erasmus University Rotterdam, Department of Anesthesiology. I'm doing research in Epidemiology, Anesthesiology and Pain Management/Palliative care. Recent projects include 1) Perioperative safety in middle-income countries, 2) Desicion making at the end of life in palliative care. I am also interested in meta-research methods as well as EBM communication topics.
Additional affiliations
June 2012 - present
Universidad del Cauca
Position
  • Postgraduate teaching activities
Description
  • Postgraduate teaching activities: Clinical epidemiology, basic statistical skills, critical literature appraisal, pain management and anesthesiology
March 2012 - present
Universidad del Cauca
Position
  • Professor (Assistant)
January 2011 - present
Erasmus MC
Position
  • Research Assistant
Education
August 2013 - July 2014
University of Puerto Rico at Rio Piedras
Field of study
  • Interventional Pain Management FIPP
July 2011 - April 2019
Erasmus University Rotterdam
Field of study
  • Perioperative Safety
August 2010 - June 2011
Erasmus University Rotterdam
Field of study
  • Health Sciences - Clinical Epidemiology

Publications

Publications (177)
Article
Full-text available
Introduction: Case reports represent a relevant, timely, and important study design in advancing medical scientific knowledge. They allow integration between clinical practice and clinical epidemiology. We aimed to assess the completeness of reporting of case reports published in high impact journals. We assessed the completeness of reporting (COR...
Article
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Postoperative pain might be different after intravenous vs. oral paracetamol. We systematically reviewed randomised controlled trials in patients >15 years that compared intravenous with oral paracetamol for postoperative pain. We identified 14 trials with 1695 participants. There was inconclusive evidence for an effect of route of paracetamol admi...
Article
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Background Use of implantable cardioverter defibrillators is increasingly common. As patients approach the end of life, it is appropriate to deactivate the shock function. Aim To assess the prevalence of implantable cardioverter defibrillator reprogramming to deactivate the shock function at the end of life and the prevalence of advance directives...
Article
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Introduction: Aging of the population and the accompanying increase in prevalence of chronic illnesses mean that more people will need palliative care. This need has not been extensively quantified in middle-income countries to policy planning and expanding health care. Objective: Provide an estimate of the need of palliative care services in...
Preprint
Full-text available
We estimated the degree to which language used in the high profile medical/public health/epidemiology literature implied causality using language linking exposures to outcomes and action recommendations; examined disconnects between language and recommendations; identified the most common linking phrases; and estimated how strongly linking phrases...
Article
Background Reported data suggest that 4.2 million deaths will occur within 30 days of surgery worldwide each year, half of which are in low- and middle-income countries. Postoperative complications are a leading cause of long-term morbidity and mortality. Patients who survive and leave the hospital after surgical complications regularly experience...
Article
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Background: Reported data suggest that 4.2 million deaths will occur within 30 days of surgery worldwide each year, half of which are in low-and middle-income countries. Postoperative complications are a leading cause of long-term morbidity and mortality. Patients who survive and leave the hospital after surgical complications regularly experience...
Article
We estimated the degree to which language used in the high profile medical/public health/epidemiology literature implied causality using language linking exposures to outcomes and action recommendations; examined disconnects between language and recommendations; identified the most common linking phrases; and estimated how strongly linking phrases...
Preprint
Background Clinical practice guidelines (CPG) are statements that provide recommendations regarding the approach to different diseases and aim to increase quality while decrease the risk of complications in health care. Numerous guidelines in the field of perioperative care have been published in the previous decade but their methodological quality...
Article
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Las revistas especializadas, de carácter científico y académico, son instrumentos fundamentales para la divulgación, acceso y validación por pares académicos de los resultados de los procesos de investigación, uno de los conceptos básicos de universidad. En Colombia, el Ministerio de Ciencia, Tecnología e Innovación considera y sostiene que es nece...
Article
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The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World...
Article
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El objetivo de este estudio fue describir las percepciones de médicos sobre la atención durante el final de la vida en pacientes oncológicos en tres hospitales de mediana y alta complejidad en Popayán y Bogotá en 2019 y 2020. Se utilizó un diseño de corte transversal descriptivo que consistió en aplicar a médicos un cuestionario auto administrado q...
Article
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Objetivo: Identificar y analizar experiencias y opiniones que pacientes oncológicos sin opción curativa tienen respecto al sistema de salud en torno a sus cuidados paliativos y deseos de final de vida. Métodos: Estudio cualitativo con perspectiva crítico-constructivista. Se realizaron 22 entrevistas en profundidad a pacientes entre 28 y 78 años con...
Article
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Background Neonatal acute kidney injury (AKI) has been associated with unfavorable outcomes, including increased mortality. We aimed to describe the clinical course and outcomes during the first 7 days after diagnosis in newborns with AKI in three neonatal intensive care units in Popayán-Colombia. Methods Multi-center prospective cohort study cond...
Article
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Background Patients with extreme body mass indices (BMI) could have an increased risk of death while hospitalized for COVID-19. Methods The database of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) was used to assess the time to in-hospital death with competing-risks regression by sex and between the categor...
Article
Full-text available
Background: Patients with extreme body mass indices (BMI) could have an increased risk of death while hospitalized for COVID-19. Methods: The database of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) was used to assess the time to in-hospital death with competing-risks regression by sex and between the catego...
Article
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BACKGROUND: The COVIDSurg collaborative was an international multicenter prospective analysis of perioperative data from 235 hospitals in 24 countries. it found that perioperative Covid-19 infection was associated with a mortality rate of 24%. at the same time, the Cover study demonstrated similarly high perioperative mortality rates in vascular su...
Article
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Members of the COVIDSurg Collaborative are co-authors of this study and are listed under the heading Collaborators. For details of role see Appendix S1. Dear Editor During the COVID-19 pandemic, multiple theories were proposed based on the observation that countries with an ongoing national Bacillus Calmette-Gué rin (BCG) immunization programme had...
Article
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SARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri‐operative or prior SARS‐CoV‐2 were at further increased risk of venous thromboembolism....
Article
Full-text available
Due to the large number of patients with severe COVID-19, many were treated outside of the traditional walls of the ICU, and in many cases, by personnel who were not trained in critical care. The clinical characteristics and the relative impact of caring for severe COVID-19 patients outside of the ICU is unknown. This was a multinational, multicent...
Article
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El final de la vida, la muerte y el morir siempre han sido temas de reflexión en diferentes épocas y culturas. En el mundo contemporáneo, estas reflexiones se han transformado de la mano de la tecnología y la atención médica altamente sofisticada. Cada día, más personas mueren en los hospitales, rodeadas de dispositivos de alta tecnología; al mismo...
Article
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Background: There is potentially considerable variation in the nature and duration of the care provided to hospitalised patients during an infectious disease epidemic or pandemic. Improvements in care and clinician confidence may shorten the time spent as an inpatient, or the need for admission to an intensive care unit (ICU) or high density unit (...
Article
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There is little evidence around the potentially protective role of previous Bacillus Calmette-Guerin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 vaccination. Prior BCG vaccination did not protect SARS-CoV-2 infected patients against postoperative pulmonary complications and 30-day mortality.
Article
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Background: GlobalSurg is an international group of researchers whose purpose is to conduct and disseminate robust collaborative, international and multicenter studies. Objective: To expose the necessary strategies and the barriers crossed in conducting massive multicenter studies in surgery. Method: During the second semester of 2020, the stu...
Article
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Background Cancer patients’ end-of-life care may involve complex decision-making processes. Colombia has legislation regarding provision of and access to palliative care and is the only Latin American country with regulation regarding euthanasia. We describe medical end-of-life decision-making practices among cancer patients in three Colombian hosp...
Article
Full-text available
Background Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction. Methods This internati...
Article
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Background The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruit...
Article
Full-text available
Background: Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction. Methods: This internati...
Article
Full-text available
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates an...
Article
Full-text available
Objectives To describe communication regarding cancer patient’s end-of-life (EoL) wishes by physicians and family caregivers. Methods An online questionnaire and telephone-based surveys were performed with physicians and family caregivers respectively in three teaching hospitals in Colombia which had been involved in the EoL care of cancer patient...
Article
Full-text available
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism....
Article
Full-text available
Objective To evaluate the methodological quality and transparency of the clinical practice guidelines (CPGs) for the prevention, diagnosis, and treatment of gestational and congenital toxoplasmosis (CT). Methods Systematic review of the literature on gestational and CT CPGs conducted in the MEDLINE, Embase, TripDatabase, Biblioteca Virtual en Salu...
Article
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We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which pati...
Article
Full-text available
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which pati...
Article
Full-text available
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which pati...
Article
Full-text available
To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the...
Article
Full-text available
To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the...
Article
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Introduction Since the beginning of the COVID-19 pandemic tens of millions of operations have been cancelled1 as a result of excessive postoper- ative pulmonary complications (51.2 per cent) and mortality rates (23.8 per cent) in patients with perioperative SARS-CoV-2 infec- tion2. There is an urgent need to restart surgery safely in order to minim...
Article
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Palliative care is on the global health agenda, as only approximately 14% of people who require palliative care receive it [...]
Article
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Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Su...
Article
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Background In Colombia, recent legislation regarding end-of-life decisions includes palliative sedation, advance directives and euthanasia. We analysed which aspects influence health professionals´ decisions regarding end-of-life medical decisions and care for cancer patients. Methods Qualitative descriptive–exploratory study based on phenomenolog...
Preprint
Full-text available
Objectives: To describe communication regarding cancer patient's end-of-life (EoL) wishes by physicians and caregivers. Methods: An online questionnaire and telephone-based surveys were performed with physicians and caregivers respectively in three teaching hospitals in Colombia who had been involved in the EoL care of cancer patients. Results: For...
Preprint
Full-text available
Background: In Colombia, recent legislation regarding end-of-life decisions includes palliative sedation, advance directives and euthanasia. We analysed which aspects influence health professionals´ decisions regarding end-of-life medical decisions and care for cancer patients. Methods: Qualitative descriptive–exploratory study based on phenomenolo...
Article
Full-text available
Postoperative COVID-19 infection is associated with increased mortality and respiratory complications highlighting the importance of shielding of patients, caregivers, and relatives.
Article
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Introduction: Euthanasia was depenalized in Colombia in 2014 as a measure that broadens the right to make decisions related to a dignified death. Currently, euthanasia continues to be a controversial topic that generates diverse opinions and positions. Objective: Explore the knowledge of the definitions and know the opinions that university student...
Article
Full-text available
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and...
Article
Full-text available
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and...
Preprint
Full-text available
Background: Cancer patients’ end-of-life care may involve complex decision-making processes. Colombia has regulations regarding palliative care and is the only Latin American country with legislation regarding euthanasia. We describe medical end-of-life decision-making practices among cancer patients in three Colombian hospitals. Methods: Attending...