Jos Vander Sloten

Jos Vander Sloten
KU Leuven | ku leuven · Section of Biomechanics

PhD

About

521
Publications
80,163
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8,784
Citations
Additional affiliations
June 1986 - present
KU Leuven
Position
  • Professor (Full)

Publications

Publications (521)
Article
Edentulism with associated severe bone loss is a widespread condition that hinders the use of common dental implants. An additively manufactured subperiosteal jaw implant (AMSJI) was designed as an alternative solution for edentulous patients with Cawood and Howell class V–VIII bone atrophy. A biomechanical evaluation of this AMSJI for the maxilla...
Article
This study aimed to reconstruct four real life vehicle-bicycle collisions and evaluates the reconstruction parameters that affect the outcome of head injuries in report based accident reconstructions. A computational model of a car was developed in the multibody software MADYMO (MAthematical DYnamic MOdeling) and was used together with a validated...
Article
Full-text available
Bridging veins (BVs) drain the blood from the cerebral cortex into dural sinuses. BVs have one end attached to the brain and the other to the superior sagittal sinus (SSS), which is attached to the skull. Relative movement between these two structures can cause BV to rupture producing acute subdural haematoma, a head injury with a mortality rate be...
Article
Full-text available
The regional dynamic mechanical properties of mouse, rat, pig, and human brain tissue were compared directly in this first-of-its-kind study. Our results suggest the use of pig or mouse brain tissue as suitable surrogates to characterise human brain tissue. The importance of this work is highlighted by the extensive use of constitutive data from an...
Article
Full-text available
Traumatic brain injury (TBI) is an important cause of mortality and morbidity worldwide. Finite element models of the human head are used widely to simulate TBI loading scenarios, to improve the understanding of the mechanical pathogenesis of head trauma. The reliability of such computational models depends strongly on the accuracy of the mechanica...
Article
Background: Assessment of glenoid bone defects is important to select the optimal glenoid component design during shoulder arthroplasty planning and implantation. This study presents a fully automated method to describe glenoid bone loss using 3-dimensional measurements without the need for a healthy contralateral reference scapula. Methods: The...
Article
Full-text available
The total number of total hip arthroplasties is increasing every year, and approximately 10% of these surgeries are revisions. New implant design and surgical techniques are evolving quickly and demand accurate preclinical evaluation. The initial stability of cementless implants is one of the main concerns of these preclinical evaluations. A broad...
Article
Full-text available
The muscle footprint anatomy of the clavicle is described in various anatomical textbooks but research on the footprint variation is rare. Our goal was to assess the variation and to create a probabilistic atlas of the muscle footprint anatomy. 14 right and left clavicles of anatomical specimens were dissected until only muscle fibers remained. 3D...
Article
Reliable computer models are needed for a better understanding of the physical mechanisms of skull fracture in accidental hits, falls, bicycle - motor vehicle & car accidents and assaults. The performance and biofidelity of these models depend on the correct anatomical representation and material description of these structures. In literature, a st...
Article
During a transcatheter aortic valve implantation, an axisymmetric implant is placed in an irregularly shaped aortic root. Implanting an incorrect size can cause complications such as leakage of blood alongside or through the implant. The aim of this study was to construct a method that determines the optimal size of the implant based on the three-d...
Article
Full-text available
Background: Altered kinematics and persisting ankle instability have been associated with degenerative changes and osteochondral lesions. Purpose: To study the effect of ligament reconstruction surgery with suture tape augmentation (isolated anterior talofibular ligament [ATFL] vs combined ATFL and calcaneofibular ligament [CFL]) after lateral l...
Article
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Conventional anatomically contoured plates do not adequately fit most tibiae. This emphasizes the need for a more thorough morphological study. Statistical shape models are promising tools to display anatomical variations within a population. Herein, we aim to provide a better insight into the anatomical variations of the tibia and tibia plateau. S...
Article
Acute subdural hematoma (ASDH) is one of the most frequent traumatic brain injuries (TBIs) with high mortality rate. Bridging vein (BV) ruptures is a major cause of ASDH. The KTH finite element head model includes bridging veins to predict acute subdural hematoma due to BV rupture. In this model, BVs were positioned according to Oka et al. (1985)....
Article
Surface registration, in which a mapping between surfaces is calculated, is a powerful tool to create patient-specific musculoskeletal and statistical shape models. However, to create these models, surface registration must assure a one-to-one correspondence between both surfaces. To enhance this process, a surface registration framework that uses...
Article
Full-text available
Background: The clavicle presents a large variability in its characterizing sigmoid shape. Prominent and nonproperly fitting fixation plates (FP) cause soft tissue irritation and lead to hardware removal. It is therefore key in FP design to account for shape variations. Statistical shape models (SSMs) have been built to analyze a cluster of complex...
Article
Full-text available
As the smallest functional unit of force production, the sarcomeres are important in determining muscle function. Actin filament lengths, which are important in determining optimal sarcomere length for a species, have not yet been reported in dogs. This study aims to provide a species‐specific value for actin filament length in dogs, while examinin...
Article
To account for proximal femoral deformities in children with cerebral palsy (CP), subject-specific musculoskeletal models are needed. Non-rigid deformation (NRD) deforms generic onto personalized bone geometry and thereby transforms the muscle points. The goal of this study was to determine to what extent the models and simulation outcomes in CP pa...
Article
A correct estimation of the material parameters from a planar biaxial test is crucial since they will affect the outcome of the finite element model in which they are used. In a virtual planar biaxial experiment, a difference can be noticed in the stress calculated from the force measured experimentally at the rakes and the actual stress at the cen...
Article
Computed tomography is used more routinely to design patient-specific instrumentation for knee replacement surgery. Its moderate imaging cost and simplified segmentation reduce design costs compared with magnetic resonance (MR) imaging, but it cannot provide the necessary cartilage information. Our method based on statistical shape modelling proved...
Article
Full-text available
Objectives The current study quantified the influence of cartilage defect location on the tibiofemoral load distribution during gait. Furthermore, changes in local mechanical stiffness representative for matrix damage or bone ingrowth were investigated. This may provide insights in the mechanical factors contributing to cartilage degeneration in th...
Data
Effect of cartilage defect location and stiffness on knee kinematics. (DOCX)
Data
The correlation coefficients between the reference and defect kinematics throughout the stance phase. (XLSX)
Data
Raw data compartimental load distribution and compressive strains. Supporting data Fig 3. (XLSX)
Data
Effect of cartilage defect location and stiffness on resultant compartmental contact force. Average tibiofemoral contact force for the different cartilage defect locations (Fig 1) throughout the stance phase of gait in the medial and lateral compartment of the tibiofemoral joint. The resultant contact force was scaled to body weight (BW). Bold labe...
Data
The root mean squared difference between the reference and defect kinematics throughout the stance phase. (XLSX)
Data
Raw data load distribution of defect and surrounding tissue throughout the stance phase of gait. Supporting data Fig 6. Average contact area [mm2]; Contact pressure [MPa]; Force [BW]; Strain [%]. (XLSX)
Data
Supplementary material: Functional assessment of strains around a full-thickness and critical sized articular cartilage defect under compressive loading using MRI
Article
Full-text available
OBJECTIVE: The objective of this study was to evaluate the effect of full-thickness chondral defects on intratissue deformation patterns and matrix constituents in an experimental model mimicking in vivo cartilage-on-cartilage contact conditions. DESIGN: Pairs of bovine osteochondral explants, in a unique cartilage-on-cartilage model system, were...
Article
Full-text available
Objective: This study aims to characterize the deformations in articular cartilage under compressive loading and link these to changes in the extracellular matrix constituents described by magnetic resonance imaging (MRI) relaxation times in an experimental model mimicking in vivo cartilage-on-cartilage contact. Design: Quantitative MRI images, T1,...
Article
Full-text available
Modal parameters are often investigated in order to assess the initial fixation of an implant. Most of studies are focused on the natural frequencies and frequency response function. Usually the femoral stem is tested although the acetabular cup fixation is important as well. The results of implant stability assessment are inconsistent and seem to...
Article
Although the form‐function relation of muscles and tendons has been studied extensively, little in vivo data exist on the musculotendon properties of the gastrocnemius complex in dogs. Using a combination of ultrasound and 3D motion tracking, musculotendon parameters were obtained in vivo from the lateral gastrocnemius muscle and the gastrocnemius...
Article
Finite element models of biomedical applications increasingly use anisotropic hyperelastic material formulations. Appropriate material parameters are essential for a reliable outcome of these simulations, which is why planar biaxial testing of soft biological tissues is gaining importance. However, much is still to be learned regarding the ideal me...
Article
Purpose: To evaluate the biomechanics of endodontically treated incisors restored with a fiberglass post and a CAD/CAM lithium-disilicate ceramic crown with/without a ferrule after thermal and mechanical aging. Materials and methods: Twenty bovine incisors were divided into two groups (n = 10): 1. Fe, with a ferrule of 2 mm, and 2. NFe, without...
Article
Full-text available
The current study aimed to assess the potential of different exercises triggering an osteogenic response at the femoral neck in a group of postmenopausal women. The osteogenic potential was determined by ranking the peak hip contact forces (HCFs) and consequent peak tensile and compressive strains at the superior and inferior part of the femoral ne...
Data
Results linear mixed models. (XLSX)
Conference Paper
Full-text available
Despite the availability of marker-based 3D motion capture systems that allow accurate description of foot kinematics and kinetics, ankle-foot specialists tend to rely mainly on plantar pressure data to evaluate foot pathologies and to describe treatment strategies. The use of pressure systems is also related to the high economical cost and long pr...
Article
Oblique impact is the most common accident situation that occupants in traffic accidents or athletes in professional sports experience. During oblique impact, the human head is subjected to a combination of linear and rotational accelerations. Rotational movement is known to be responsible for traumatic brain injuries. In this article, composite fo...
Article
Patient-specific biomechanical modelling can improve preoperative surgical planning. This requires patient-specific geometry as well as patient-specific material properties as input. The latter are, however, still quite challenging to estimate in vivo. This study focuses on the estimation of the mechanical properties of the arterial wall. Firstly,...
Article
Full-text available
Anisotropy in foams generally originates from cell elongation in a certain direction. In this study, a composite concept is utilized to create anisotropy in foams at macro level. For this, layered composite foam is proposed by combining discrete layers of expanded polystyrene foam foam with different densities. The layers are positioned in parallel...
Article
Objective: The aim of the study was to investigate the influence of tube current reduction on the segmentation accuracy of the scapula. Methods: A human cadaver was computed tomography scanned multiple times while reducing tube current amperage. The images were segmented using 2 different segmentation methods (N = 28). Subsequently the scapula w...
Article
Full-text available
The flexible nature of the Single Point Incremental Forming process implies that it is well-suited for small batch production and rapid prototyping of complex sheet metal parts. To overcome the process limits and to improve the accuracy, methods that alter the tool paths used to generate the part, like multi-step tool paths or compensated tool path...
Article
Finite element (FE) simulations are increasingly valuable in assessing and improving the performance of biomedical devices and procedures. Due to high computational demands such simulations may become difficult or even infeasible, especially when considering nearly incompressible and anisotropic material models prevalent in analyses of soft tissues...
Article
A commonly heard concern in the Ross procedure, where a diseased aortic valve is replaced by the patient's own pulmonary valve, is the possibility of pulmonary autograft dilatation. We performed a biomechanical investigation of the use of a personalized external aortic root support or exostent as a possibility for supporting the autograft. In ten s...
Article
Rotational acceleration of the head is known to be the cause of traumatic brain injuries. It was hypothesized that by introducing anisotropy in a foam liner in head protection applications, for example, protective helmets, rotational acceleration transmitted to the head can be further mitigated. Therefore, composite foam with a cylinder/matrix conf...
Article
Background: Description of the native shape of a glenoid helps surgeons to preoperatively plan the position of a shoulder implant. A statistical shape model (SSM) can be used to virtually reconstruct a glenoid bone defect and to predict the inclination, version, and center position of the native glenoid. An SSM-based reconstruction method has alre...
Article
Plantar pressure simulation driven by integrated 3D motion capture data, using both a finite element and a discrete element model, is compared for ten healthy and ten diabetic neuropathic subjects. The simulated peak pressure deviated on average between 16.7 and 34.2% from the measured peak pressure. The error in the position of the peak pressure w...
Article
The preoperative diagnosis of loosening of cemented tibial knee implants is challenging. This feasibility study explored the basic potential of a vibration-based method as an alternative diagnostic technique to assess the fixation state of a cemented tibia implant and establish the method's sensitivity limits. A combined in vitro and in silico appr...
Article
Background: Component malalignment remains a major concern in total knee arthroplasty (TKA). Patient-specific guides (PSG) were developed to increase accuracy of bone resections and component placement, but available evidence is contradictory. We assessed the accuracy of 3D component placement in TKA with PSG compared to conventional surgery using...
Technical Report
Full-text available
Advances in medical technology have spurred an evolution towards personalized medicine for improved healthcare delivery and patient outcomes. Three-dimensional (3D) printing, also referred to as additive manufacturing, has become an important contributor to this evolution and remains an essential technology in our healthcare system of the future. W...
Article
Wall stress estimation through biomechanical simulations represents a promising tool to support aneurysm risk stratification and has the potential to provide a more individual risk assessment. Accurate computation of the stress field necessitates the use of robust and biofidelic models based on patient-specific information. A multidisciplinary appr...
Conference Paper
Full-text available
People with diabetes can develop many different foot complications with the worst being diabetic foot, which compromises the function and structure of the foot and may lead to plantar ulcers and amputations. Several authors have demonstrated a close relationship between neuropathy and foot biomechanical alterations that, leading to an increased pla...
Article
Full-text available
Polymeric foams are extensively used in applications such as packaging, sports goods and sandwich structures. Since in-service loading conditions are often multi-axial, characterisation of foams under multi-axial loading is essential. In this article, quasi-static combined shear-compression behaviour of isotropic expanded polystyrene foam and aniso...