Jorge Villanua

Introduction Glioblastoma is the most common primary brain tumour. Despite advances in treatment, its prognosis remains dismal, with a mean survival time of about 14 months. Many articles have addressed direct costs, those associated with the diagnosis and treatment of the disease. Indirect costs, those associated with loss of productivity due to t...

Introducción: El glioblastoma es el tumor cerebral más frecuente. A pesar de los avances en su tratamiento, el pronóstico sigue siendo pobre, con una supervivencia media en torno a los 14 meses. Los costes directos, aquellos asociados al diagnóstico y el tratamiento de la enfermedad, han sido descritos ampliamente. Los costes indirectos, aquellos d...

Glioblastoma is the most common, aggressive and lethal brain tumor in adults. However, current therapeutic protocols have low success rates, and average overall survival is less than 15 months. The resistance to therapy is largely a result of the remarkable cellular and phenotypical heterogeneity that characterizes this type of tumor. The discovery...

The Neuro-Oncology Study Group (NOSG) at SENEC has commissioned the elaboration of the present document to the Neuro-Oncology Committee at Donostia University Hospital. It is intended to serve as a NOSG Consensus Guide and a proposed recommendation for the management of this pathological condition at all Spanish Hospitals, both public and private....

The Neuro-Oncology Study Group (NOSG) at SENEC has commissioned the elaboration of the present document to the Neuro-Oncology Committee at Donostia University Hospital. It is intended to serve as a NOSG Consensus Guide and a proposed recommendation for the management of this pathological condition at all Spanish Hospitals, both public and private.N...

Dynamic velocity-encoded Phase-contrast MRI (PC-MRI) techniques are being used increasingly to quantify pulsatile flows for a variety of flow clinical application. A method for igh resolution segmentation of cerebrospinal fluid (CSF) velocity is described. The method works on PC-MRI with high temporal and spatial resolution. It has been applied in...

Detection of Alzheimer’s disease over brain Magnetic Resonance Imaging (MRI) data is a priority goal in the Neurosciences. In previous works we have studied the accuracy of feature vectors obtained from VBM studies of the MRI data. In this paper we report results working on deformation based features, obtained from the deformation vectors computed...

Detection of Alzheimer's disease on brain Magnetic Resonance Imaging (MRI) is a highly sought goal in the Neurosciences. We used four different models of Artificial Neural Networks (ANN): Back-propagation (BP), Radial Basis Networks (RBF), Learning Vector Quantization Networks (LVQ) and Probabilistic Neural Networks (PNN) to perform classification...

In this paper we explore the use of the Voxel-based Morphometry (VBM) detection clusters to guide the feature extraction processes for the detection of Alzheimer’s disease on brain Magnetic Resonance Imaging (MRI). The voxel location detection clusters given by the VBM were applied to select the voxel values upon which the classification features w...

We have studied feature extraction processes for the detection of Alzheimer’s disease on brain Magnetic Resonance Imaging (MRI) based on Voxel-based morphometry (VBM). The clusters of voxel locations detected by the VBM were applied to select the voxel intensity values upon which the classification features were computed. We have explored the use o...

This case illustrates the correlation between Magnetic Resonance Imaging (MRI) and the pathological findings in a case of cavernous sinus (CS) aspergilloma.

Objective To analyze diagnostic discrepancies found between magnetic resonance (MR) and arthroscopy, and to determine the reasons that they occur.Materials and Methods Two-hundred and forty-eight MR knee explorations were retrospectively checked. Forty of these showed diagnostic discrepancies between MR and arthroscopy. Two radiologists independent...

Aim To analyze the merit and repercussions of measuring magnetic resonance (MR) activity in units of radiological activity, and of using complexity index (CI) as an activity indicator. Materials and methods We studied the MR activity of Osatek, Inc. during an 8-year period (1994-2001). We measured this activity both in number of MR procedures perf...

Objective: To analyze diagnostic discrepancies found between magnetic resonance (MR) and arthroscopy, and to determine the reasons that they occur. Materials and Methods: Two-hundred and forty-eight MR knee explorations were retrospectively checked. Forty of these showed diagnostic discrepancies between MR and arthroscopy. Two radiologists independ...

Lipoblastoma is a soft tissue tumor that usually affects children under 3 years old. It typically occurs in the extremities. There have been few cases studied by MR, its interest lying in an unusual behavior exhibited by (señal grasa). We present the case of a tumor in a 16-month-old patient along with localization and MR findings typical of this e...

To compare turbo T2 weighted spin echo (TSE T2) and turbo-FLAIR (fluid attenuated inversion recovery) vs gadolinium enhanced T1 weighted spin echo (SE T1) sequence in the differential diagnosis between disc herniation and post-surgical fibrosis. Sixty-four patients who underwent surgical treatment for lumbar disc herniation with persistent or recur...

The lateral aspect of the knee is stabilized by a complex arrangement of ligaments, tendons, and muscles. These structures can be demonstrated with routine spin-echo magnetic resonance (MR) imaging sequences performed in the sagittal, coronal, and axial planes. Anterolateral stabilization is provided by the capsule and iliotibial tract. Posterolate...

We report a 61-year-old alcoholic man who presented with subacute physical deterioration and severe dysarthria. MRI, suggestive of corpus callosum demyelination with associated white matter involvement in both cerebral hemispheres, indicated the diagnosis of Marchiafava-Bignami disease. During his stay in hospital the patient showed remarkable impr...

Objective: To evaluate the discriminatory power of T2-weighted turbo spin-echo (T2 TSE) sequences in the differential diagnosis of liver metastases and benign lesions in patients with colorectal adenocarcinoma. Material and methods: A retrospective analysis was done of the magnetic resonance (MR) studies performed between 1994 and 1997 in 44 patien...

Presentamos nuestra experiencia con un método de localización lesional preoperatoria craneorraquídea, mediante la correlación entre la imagen de la Resonancia Magnética y la vitamina E como marcador cutáneo. Esta técnica permite, de una manera simple pero precisa, el centraje de la incisión quirúrgica fundamentalmente en el abordaje a lesiones córt...

Pancreatic location of hydatid disease is exceptional. We report our findings in a 10-year-old asymptomatic patient who was admitted because of epigastric trauma. Radiological findings were considered secondary to trauma and therefore undervalued.