Jorge Gabriel Ruiz Sánchez

Jorge Gabriel Ruiz Sánchez
Fundación Jiménez Díaz | IIS-FJD

Medical Doctor
Clinical endocrinologist focused in cardiovascular risk, hypertension, diabetes, and adrenal and sodium/water disorders

About

46
Publications
2,680
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95
Citations
Introduction
Clinical Endocrinologist and Researcher. Interests: *Dysnatremia, water/sodium metabolism and adrenal disorders *Cardiovascular risk, Hypertension and Diabetes

Publications

Publications (46)
Article
Full-text available
Background: Overcorrection of serum sodium (SNa) during therapy of hyponatremia can result in osmotic demyelination syndrome. Our aim was to determine the relationship between the isotonic saline solution dose (ISSD) administered and the 24‐h SNa increase (24SNa) in patients with hypovolemic hyponatremia (HH). Methods: Retrospective study of HH pat...
Article
Full-text available
Dysnatremia is associated with increased mortality in patients with community-acquired pneumonia. SARS-COV2 (Severe-acute-respiratory syndrome caused by Coronavirus-type 2) pneumonia can be fatal. The aim of this study was to ascertain whether admittance dysnatremia is associated with mortality, sepsis, or intensive therapy (IT) in patients hospita...
Poster
Full-text available
Abstract. Endocrinol Diabetes Nutr. 2020;67(Espec Cong 2):5 Available in: https://www.elsevier.es/es-revista-endocrinologia-diabetes-nutricion-13-congresos-congreso-seen-2020-112-sesion-neuroendocrinologia-y-suprarrenal-6100-comunicacion-hiponatremia-en-el-hipoaldosteronismo-caracteristicas-72804
Article
Full-text available
Over the last years, there has been an increase in adverse food reactions, probably associated with life style changes in the past decades. An adverse food reaction is any clinically abnormal response that can be attributed to ingestion, contact or inhalation of a food, its derivatives or an additive contained in it. They can be classified as food...
Article
Resumen Objetivo Valorar la indicación y los medios para cribado/diagnóstico del hiperaldosteronismo primario (HAP) en las unidades de Endocrinología de España. Materiales y métodos Se realizó, por parte del grupo AdrenoSEEN, una encuesta electrónica anónima en 2 fases (2020/2021) a los miembros de la SEEN con datos sobre cribado, pruebas de conf...
Article
Full-text available
Background and Objectives: Differentiating between hypovolemic (HH) and euvolemic hy-ponatremia (EH) is crucial for correct diagnosis and therapy, but can be a challenge. We aim to ascertain whether changes in serum creatinine (SC) can be helpful in distinguishing HH from EH. Materials and Methods: Retrospective analysis of patients followed in a m...
Article
Full-text available
Objective The aim of this study was to evaluate the rate of adrenal venous sampling (AVS) performance in patients with primary aldosteronism (PA), the main reasons for its non-performance, and the success and complications rate of this procedure in Spain. Moreover, the concordance between CT/MRI and AVS for PA subtyping was evaluated. Methods A re...
Article
Full-text available
Objective To analyze the evolution of the cardiometabolic profile of patients with primary hyperaldosteronism (PA) after the treatment with surgery and with mineralocorticoid receptor antagonists (MRA). Design Retrospective multicentric study of patients with PA on follow-up in twelve Spanish centers between 2018 and 2020. Results 268 patients wi...
Article
Resumen Introducción La hiponatremia es el trastorno electrolítico más prevalente tanto en medio ambulatorio como hospitalario. A pesar de esta frecuencia, la hiponatremia, incluso la grave, es frecuentemente infravalorada e inadecuadamente tratada, lo que pone de manifiesto la necesidad de elaborar documentos de consenso y guías de práctica clíni...
Article
Full-text available
Objective: To compare the presentation and evolution of primary aldosteronism (PA) in elderly (≥65 years) and young patients (<65 years). Methods: A retrospective multicenter study performed in 20 Spanish hospitals of PA patients in follow-up between 2018-2021. Results: 352 patients with PA <65 years and 88 patients ≥65 years were included. Older P...
Article
Full-text available
Introduction Hyponatremia often occurs during the practice of endurance sports. We evaluated the impact on hyponatremia of the hydration recommendations of the Third International Exercise-Associated Hyponatremia Consensus Development Conference 2015 (3IE-AHCD) during the 2017 Gran Trail de Peñalara marathon (GTP) and the Vitoria Gasteiz Ironman tr...
Article
Full-text available
The definition of primary hyperaldosteronism (PA) has shifted, as progress has been made in understanding the disease. PA can be produced by unilateral or bilateral cortical adrenal hyperproduction of aldosterone, due to hyperplasia, aldosterone-secreting cell clusters, aldosterone-producing macro or micro adenoma/s, and combinations of the above,...
Article
Full-text available
A pre-gestational thyroid reserve of iodine is crucial to guarantee the increased demand for thyroid hormone production of early pregnancy. An iodine intake ≥150 µg/day is currently recommended. The objective of this study was to assess average pre-gestational food-based iodine consumption in pregnant women at their first prenatal visit (<12 gestat...
Article
Full-text available
The optimal maternal levels of thyroid hormones (TH) during the first trimester of gestation have not been established, nor has the ideal moment to initiate levothyroxine treatment (LT) to improve the evolution of gestation and fetal development. Cut-off points for Thyroid-stimulating hormone (TSH) <2.5 µIU/mL and free thyroxine (FT4)>7.5 pg/mL hav...
Article
Full-text available
SARS-COV2 infection has swiftly become a pandemic disease of historic relevance and widely variable outcomes. This variable prognosis is related both to uneven damage, among others, to lungs, heart and kidneys, and to a multisystemic inflammatory reaction. All these factors are known to disrupt water balance and potentially induce hyponatraemia or...
Preprint
Full-text available
BACKGROUND Hyponatremia is a frequent electrolytic disorder in hospitalized patients with Coronavirus Disease 2019 (COVID-19). Inflammatory status could be associated with hyponatremia in patients with COVID-19. We evaluate the hospital evolution of hyponatremia and inflammation markers in COVID-19 patients.METHODSA case-series of adult patients wi...
Preprint
Full-text available
Background: Hyponatremia is the most frequent hydroelectrolytic disorder in hospitalized patients and is associated with mortality. A lack in the diagnostic and therapeutic management of the hyponatremic hospitalized patient has been reported. Hyponatremia in hospitalized patients is usually managed by specialties other than nephrology and endocrin...
Article
Objectives: To describe a rare association of two endocrine tumours in a clinical case. Case presentation: A 54-year-old woman with a classic Papillary thyroid cancer (PTC) assessed by the Endocrinology Department of a tertiary hospital from May-2015 to May-2020. PTC was treated with a total thyroidectomy and lymphadenectomy in May-2015. Initial...
Poster
Full-text available
INTRODUCCION La clasificación volémica de la hiponatremia es esencial para su diagnóstico y tratamiento. Diferenciar entre la hiponatremia hipovolémica (HH) y la hiponatremia euvolémica (HE) puede representar un reto. Fundamentalmente cuando el sodio urinario (NaU) es >30mmol/L como sucede en el hipoaldosteronismo y el Síndrome de inadecuada antidi...
Poster
Full-text available
This study reveals the usefulness of the serum Na-Creatinine relationship for the determination of volume status in hyponatremic patients. Available in: https://www.elsevier.es/es-revista-endocrinologia-diabetes-nutricion-13-pdf-X2530016419002510
Poster
Full-text available
How do we measure volemia in Hyponatremic patients? Blood pression is not useful. Available in: https://www.elsevier.es/es-revista-endocrinologia-diabetes-nutricion-13-congresos-congreso-seen-2019-latam-congress-101-sesion-neuroendocrinologia-5491-comunicacion-presion-arterial-un-parametro-de-64713#
Poster
Full-text available
In patients with hypovolemic hyponatremia we observed a decrease of serum potassium, serum creatinine and serum urea during the hypovolemic hyponatremia treatment. It is probably explained by a renin-angiotensin-aldosterone system hyperactivation. Available in: https://www.elsevier.es/es-revista-endocrinologia-diabetes-nutricion-13-pdf-X253001641...
Poster
Full-text available
*It is linked to a Original Research titled "The Effect of the Dose of Isotonic Saline on the Correction of Serum Sodium in the Treatment of Hypovolemic Hyponatremia" and published in Journal of Clinical Medicine (DOI: 10.3390/jcm9113567). *Poster is available in: https://www.elsevier.es/es-revista-endocrinologia-diabetes-nutricion-13-pdf-X2530016...
Article
Full-text available
Over the last years, there has been an increase in adverse food reactions, probably associated with life style changes in the past decades. An adverse food reaction is any clinically abnormal response that can be attributed to ingestion, contact or inhalation of a food, its derivatives or an additive contained in it. They can be classified as food...
Poster
Full-text available
El clivus, procedente del cuerpo del esfenoides y de porción media del occipital, está situado en la región selar posterior, se continúa anteriormente con la apófisis clinoides posterior (ACP), que en un corte sagital, forman un ángulo obtuso en relación a la línea cráneo-caudal trazada por el tallo hipofisario; así, la región selar adopta la forma...
Article
Full-text available
Unlabelled: Irritable Bowel Syndrome (IBS) is a condition whose prevalence varies according to the method used to diagnose. Objective: To determine the prevalence of Intestinal bowel Syndrome (IBS) on Chiclayo-Peru during 2011. Material and methods: Target population: people aged 18 to 60 years. Study design: Cross-sectional. Sample size:...
Article
Full-text available
Irritable Bowel Syndrome (IBS) is a condition whose prevalence varies according to the method used to diagnose. Objective: To determine the prevalence of Intestinal bowel Syndrome (IBS) on Chiclayo - Peru during 2011. Material and methods: target population: people aged 18 to 60 years. Study Design: Cross-sectional. Sample size: 195 persons, multis...

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