Joon Faii Ong

Joon Faii Ong
Harvard Medical School | HMS · Department of Medicine

About

8
Publications
4,355
Reads
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1,226
Citations
Citations since 2016
0 Research Items
1102 Citations
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2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200

Publications

Publications (8)
Article
http://www.bmj.com/content/349/bmj.g7346/rr-6 To the Editor: It is exceptionally heartening to finally see a scientific investigation into the claims by one of the most popular medical professionals on mass media. In light of the previous rapid responses, perhaps it would be useful to have one from a young trainee in the medical field – an indivi...
Article
Aims: Achieving significant adhesion to soft tissues while minimizing tissue damage poses considerable clinical challenge. This is especially so in burns or chronic wounds, given the necessity of skin grafts in treatment. Chemical-based adhesives require tissue-specific reactive chemistry, typically inducing a sig- nificant inflammatory response. S...
Article
Aims: Inadequate immunomodulatory potency of mesenchymal stem cells (MSC) may limit their ability to treat numerous inflammatory conditions, with clinical studies yielding mixed results. Here we show that budesonide significantly augmentsMSC expression of indoleamine-2,3-dioxygenase (IDO), a primary mediator of MSC immunomodulatory function. We add...
Article
Introduction: MSC are being explored to treat numerous inflammatory pathologies, but clinical studies have yielded mixed results, likely due to vari- ability in MSC potency. Here we show that budesonide significantly augments MSC expression of IDO , a primary mediator of MSC immunomodulatory function. We additionally describe a strategy to continuo...
Article
Full-text available
Inadequate immunomodulatory potency of mesenchymal stem cells (MSC) may limit their therapeutic efficacy. We report glucocorticoid steroids augment MSC expression and activity of indoleamine-2,3-dioxygenase (IDO), a primary mediator of MSC immunomodulatory function. This effect depends on signaling through the glucocorticoid receptor and is mediate...
Article
Full-text available
The diverse immunomodulatory properties of mesenchymal stem/stromal cells (MSCs) may be exploited for treatment of a multitude of inflammatory conditions. MSCs have long been reported to be hypoimmunogenic or 'immune privileged'; this property is thought to enable MSC transplantation across major histocompatibility barriers and the creation of off-...
Article
Tissue engineering (TE) and regenerative medicine are a blend of developmental biology, life sciences, and engi- neering efforts that attempts to address clinical problems. Tissue engineering was defined in 1988 as the application of principles and methods of engineering and life sciences toward fundamental understanding of structure? function rela...

Questions

Question (1)
Question
My lab is currently looking for the above cells, but unfortunately, can't find anyone with these cells.

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