Jongman Kim

• M.D., Ph.D.
• Professor (Full) at Sungkyunkwan University

BACKGROUND Surgical consent forms must convey critical information, yet their complex language can limit patient comprehension. Large language models (LLMs) may improve readability, but evidence of their impact on content preservation is lacking in non-English contexts. OBJECTIVE This study evaluates the impact of LLM-assisted editing on the reada...

Liver transplantation (LT) is an essential treatment for patients with end-stage liver disease (ESLD), including hepatocellular carcinoma (HCC). Post-transplant complications such as venous congestion and tumor recurrence remain challenging, and recent studies suggest that ischemia-reperfusion injury (IRI) and the resulting inflammatory response pl...

Background In the current “sickest first” allocation policy for limited deceased liver grafts, identifying patients “too sick to transplant” before transplantation is crucial to optimize outcomes. This study aimed to predict futile outcomes following deceased donor liver transplantation (DDLT) in patients with Model for End-Stage Liver Disease-Sodi...

Background Rifabutin (Rfb) is commonly administered instead of rifampicin for the treatment of tuberculosis (TB) in SOTR to avoid substantial drug interaction of rifampin. However, evidence of its efficacy is scarce. Methods We conducted a retrospective, case-control study at Samsung Medical Center. The SOTR group included SOTR aged ≥ 18 years who...

Background Early allograft dysfunction (EAD) affects outcomes in liver transplantation (LT). Existing risk models developed for deceased-donor LT depend on posttransplant factors and fall short in living-donor LT (LDLT), where pretransplant evaluations are crucial for preventing EAD and justifying the donor’s risks. Methods This retrospective stud...

The first report is presented on the fabrication of anisotropic Janus polydiacetylene (PDA) microparticles with dual colorimetric properties. Spherical proto‐PDA particles are initially created by drying an emulsion containing 10,12‐pentacosadiynoic acid (PCDA) monomers, followed by UV polymerization. By heating an aqueous dispersion of these PDA p...

Background While evidence from preclinical and observational cohort studies have suggested potential disparities in tumour behaviour associated with the choice of intra‐operative anaesthetics, clinical evidence of tumour recurrence and metastasis remains inconclusive. We aimed to compare the impact of intra‐operative anaesthesia on oncologic outcom...

Background Medical accessibility is important in liver transplantation (LT) because of the risk of infections associated with the use of immunosuppressants and complications that require continuous treatment, such as biliary stenosis. However, the effect of medical accessibility on LT success rates has yet to be scrutinized. The aim of this retrosp...

cle distributed under the terms of the Creative Commons Attribu-tion Non-Commercial License (http://cre-ativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Colorectal cancer (CRC) poses a significant global health challenge,...

Decompensated cirrhotic patients experience severely increased intestinal permeability and bacterial translocation. Thus, autologous blood salvaged during deceased donor liver transplantation (DDLT) may be contaminated with enteric bacteria. We aimed to evaluate bacterial contamination of autologous blood salvaged during DDLT and its association wi...

Purpose: Right-sided tumors have been reported to have a poorer survival rate than left-sided tumors; however, there remains debate regarding whether sidedness is an independent prognostic factor in colorectal cancer liver metastasis (CRLM). This study aimed to assess the impact of sidedness on prognosis in resectable CRLM and to identify prognost...

Pure laparoscopic donor hepatectomy (PLDH) has become a standard practice for living donor liver transplantation in expert centers. Accurate understanding of biliary structures is crucial during PLDH to minimize the risk of complications. This study aims to develop a deep learning-based segmentation model for real-time identification of biliary str...

Backgrounds/Aims While large-for-size syndrome is uncommon in liver transplantation (LT), it can result in fatal outcome. To prevent such fatality, we manufactured 3D-printed intra-abdominal cavity replicas to provide intuitive understanding of the sizes of the graft and the patient’s abdomen in patients with small body size between July 2020 and F...

Background Living-donor liver transplantation has been widely performed as an alternative to the scarce liver grafts from deceased donors. More studies are reporting favorable outcomes of left liver graft (LLG). This study compared the clinical outcomes between living-donor liver transplantation using LLG and right liver graft (RLG) with similar gr...

Polydiacetylenes (PDA) are highly regarded for their unique colorimetric and fluorescent responses, making them ideal for sensor development. Despite their potential, conventional methods for fabricating biocompatible PDA‐encapsulated hydrogel sensor beads often fail to offer precise control over bead size and morphology. This study introduces a co...

Purpose: This study aimed to determine whether micro-flow imaging (MFI) offers diagnostic performance comparable to that of contrast-enhanced ultrasonography (CEUS) in detecting segmental congestion among patients undergoing living donor liver transplantation (LDLT). Methods: Data from 63 patients who underwent LDLT between May and December 2022...

Accurate identification of the bile duct bifurcation site is crucial in pure laparoscopic donor right hepatectomy (PLDRH) for living donor liver transplantation. This study aimed to develop and evaluate an artificial intelligence (AI) model to predict the location of bile duct bifurcation during PLDRH procedures. In this single-institution retrospe...

Objectives Sepsis is a leading global cause of mortality, and predicting its outcomes is vital for improving patient care. This study explored the capabilities of ChatGPT, a state-of-the-art natural language processing model, in predicting in-hospital mortality for sepsis patients. Methods This study utilized data from the Korean Sepsis Alliance (...

Purpose The purpose of this study is to build a prediction model for estimating graft weight about different graft volumetry methods combined with other variables. Methods Donors who underwent living-donor right hepatectomy from March 2021 to March 2023 were included. Estimated graft volume measured by conventional method and 3-dimensional (3D) so...

Monitoring mechanical stresses in microchannels is challenging. Herein, we report the development of a mechanofluorescence sensor system featuring a fluorogenic single polydiacetylene (PDA) particle, fabricated using a co-flow microfluidic method. We construct a stenotic vessel-mimicking capillary channel, in which the hydrodynamically captured PDA...

We assessed the value of the diffusion-weighted image (DWI) for predicting intrahepatic biliary complications (IHBC) after ABO-incompatible liver transplantation (ABOi-LT), potentially leading to refractory cholangitis. In this retrospective study at a single center, 56 patients who underwent ABOi-LT from March 2021 to January 2023 were analyzed. A...

Pure laparoscopic donor hepatectomy (PLDH) has become a standard practice for living donor liver transplantation (LDLT) in expert centers. Accurate understanding of biliary structures is crucial during PLDH to minimize the risk of complications. This study aims to develop a deep learning-based segmentation model for real-time identification of bili...

Solvatochromism plays a pivotal role in various scientific and technological fields including those that explore molecular interactions, sensing technologies, and organic electronics. Notably, despite their ease of manipulation, direct visualization, and potential for single particle‐based sensing, micro‐sized solid particles have been the focus of...

Background Precise preoperative assessment of liver vasculature and volume in living donor liver transplantation is essential for donor safety and recipient surgery. Traditional manual segmentation methods are being supplemented by deep learning (DL) models, which may offer more consistent and efficient volumetric evaluations. Methods This study a...

To assess the prognostic impact of preoperative MRI features on outcomes for single large hepatocellular carcinoma (HCC) (≥ 8 cm) after surgical resection. This retrospective study included 151 patients (mean age: 59.2 years; 126 men) with a single large HCC who underwent gadoxetic acid-enhanced MRI and surgical resection between 2008 and 2020. Cli...

Introduction This study examined associations between the graft-to-recipient weight ratio (GRWR) for adult-to-adult living donor liver transplantation (LDLT) and HCC outcomes. Materials and Methods Data from patients in the Korean Organ Transplantation Registry who underwent LDLT for HCC from 2014–2021 were retrospectively reviewed. Patients were...

In liver transplantation, the primary concern is to ensure an adequate future liver remnant (FLR) volume for the donor, while selecting a graft of sufficient size for the recipient. The living donor–resection and partial liver segment 2−3 transplantation with delayed total hepatectomy (LD−RAPID) procedure offers a potential solution to expand the d...

Background In liver transplantation (LT), large-for-size syndrome is not common but can result in fatal outcome. To prevent such fatal outcome, we manufactured 3-D printed intra-abdominal cavity to give intuitive understanding of the sizes of the graft and patient’s abdomen in patients with small body size between July 2020 to February 2022. Metho...

Laparoscopic liver resection (LLR) remains controversial in the treatment of intrahepatic cholangiocarcinoma (ICC). The aim of the present study is to investigate the outcomes of LLR for ICC compared to open liver resection (OLR). We retrospectively reviewed patients who underwent surgery for ICC between January 2013 and February 2020. OLR and LLR...

Backgrounds/Aims Prolonged use of steroids after liver transplantation (LT) significantly increases the risk of diabetes or cardiovascular disease, which can adversely affect patient outcomes. Our study evaluated the effectiveness and safety of early steroid withdrawal within the first year following LT. Methods This study was conducted as an open...

Cytomegalovirus (CMV) is the most important opportunistic viral pathogen in solid organ transplant (SOT) recipients. The Korean guideline for the prevention of CMV infection in SOT recipients was developed jointly by the Korean Society for Infectious Diseases and the Korean Society of Transplantation. CMV serostatus of both donors and recipients sh...

Background Recently, the outcomes of surgical treatment for advanced hepatocellular carcinoma (HCC) have improved. However, despite the technical advancements in laparoscopic liver resection (LLR), it is still not recommended as the standard treatment for HCC with portal vein tumor thrombosis (PVTT) because of the poor oncological outcomes. This st...

Liver transplantation is a highly complex and challenging field of clinical practice. Although it was originally developed in western countries, it has been further advanced in Asian countries through the use of living donor liver transplantation. This method of transplantation is the only available option in many countries in the Asia-Pacific regi...

Purpose Hepatocellular carcinoma (HCC) is a significant health concern, and the complexity of liver anatomy poses challenges in conveying radiologic findings and surgical plans to patients. This study aimed to evaluate the impact of a virtual reality (VR) education program on anxiety and knowledge in HCC patients undergoing hepatic resection. Meth...

Background/Aim Hepatocellular carcinoma (HCC) tumor thrombi located in the first branch of the portal vein (Vp3) or in the main portal trunk (Vp4) are associated with poor prognosis. This study aimed to investigate the clinicopathological characteristics and risk factors for HCC recurrence and mortality following liver resection (LR) in patients wi...

Functional supramolecular materials exhibit important features including structural versatility and versatile applications. Here, this study reports the construction of unique hierarchically organized nanotoroids exhibiting fluorescence, photocatalytic, and sensing properties. The nanotoroids comprise of macrocyclic diacetylenes (MCDA) and 8‐anilin...

Background This study aimed to develop an automated segmentation system for biliary structures using a deep learning model, based on data from magnetic resonance cholangiopancreatography (MRCP). Materials and methods Living liver donors who underwent MRCP using the gradient and spin echo technique followed by three-dimensional modeling were eligib...

Purpose To investigate the imaging features indicating portal vein invasion (PVI) of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced MRI and to create more accurate diagnostic criteria than the presence of portal vein tumor thrombosis (PVTT) on MRI. Methods This retrospective study included patients with surgically resected HCC larger th...

Recent advancements in deep learning have facilitated significant progress in medical image analysis. However, there is lack of studies specifically addressing the needs of surgeons in terms of practicality and precision for surgical planning. Accurate understanding of anatomical structures, such as the liver and its intrahepatic structures, is cru...

Background and Aims Living liver donation with high model for end‐stage liver disease (MELD) score was discouraged despite organ shortage. This study aimed to compare graft survival between living donor liver transplantation (LDLT) and deceased donor liver transplantation (DDLT) recipients with extremely high‐MELD (score of ≥35). Methods Between 2...

Objective To compare graft survival after LDLT in patients receiving GRWR<0.8 versus GRWR≥0.8 grafts and identify risk factors for graft loss using GRWR<0.8 grafts. Summary Background Data Favorable outcomes after living donor liver transplantation (LDLT) using graft-to-recipient weight ratio (GRWR)<0.8 grafts were recently reported; however, thes...

Purpose The skeletal muscle index (SMI) at the L3 level is widely used to diagnose sarcopenia. The upper thigh (UT) also reflects changes in whole-body muscle mass, but no study has examined this using the UT to diagnose sarcopenia in liver transplantation (LT). This study aimed to determine an optimal cut-off value for UT-SMI and investigate how s...

End-stage liver and kidney disease is an indication for simultaneous liver and kidney transplantation. However, in countries where deceased donor transplantation is not well established, living donor liver transplantation (LDLT) is a realistic option for patients on hemodialysis (HD). We investigated the outcomes of LDLT for patients on HD. We cond...

Background: Systemic treatment options for hepatocellular carcinoma (HCC) after liver transplantation (LT) are limited in patients in whom sorafenib treatment was failed. The purpose of our study was to compare outcomes among sorafenib, regorafenib, and nivolumab treatment groups in patients with recurrent HCC after LT. Methods: This study retrospe...

Living liver donors (LLDs) are screened for transmissible diseases including cancer. We investigated the actual cancer incidence of LLDs compared with a matched healthy control group from the general Korean population using data from the Korean National Health Insurance Services (NHIS). A total of 12,372 LLDs who donated a liver graft between 2002...

Purpose: Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified. Methods: From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with...

Stretchable interconnects, essential to the versatility of stretchable circuit boards (SCBs) in the emerging field of wearable electronic systems, are commonly made from conductive elastomer composites. However, the simultaneous realization of exceptional performance and a simple and reproducible fabrication has proven to be a challenge. In this st...

We present a summary of the evidence on testing for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and organ procurement from deceased donors and provide recommendations based on current clinical data and the guidelines from major transplant organizations. Because of the limited historical experience with coronavirus disease 2019 (COV...

Simple Summary Liver transplantation is the last chance for patients with hepatocellular carcinoma (HCC) who can no longer be treated. However, not all HCC patients are eligible for a liver transplant. There are several conditions that are eligible for liver transplantation. Among them, portal vein tumor thrombus (PVTT) is treated as a contraindica...

2D nanostructures including monolayers and few layers exhibit unique properties originating from the anisotropic ultrathin nature. Conventional organic 2D nanostructures, such as covalent organic frameworks, are comprised of the planar π‐conjugated macromolecules linked and extended parallel to the layers. The present work shows a new type of exfol...

Greater graft-failure-risk of female-to-male liver transplantation (LT) is thought to be due to acute decrease in hepatic-estrogen-signaling. Our previous research found evidence that female hepatic-estrogen-signaling decreases after 40 years or with macrosteatosis. Thus, we hypothesized that inferiority of female-to-male LT changes according to do...

This study analyzed the risk of liver retransplantation and factors related to better outcome. Adult liver transplantations performed during 1996–2021 were included. Comparison between first transplantation and retransplantation were performed. Among retransplantation cases, comparison between whole liver and partial liver graft was performed. Mult...

Objectives: To assess whether the Liver Imaging Reporting and Data System (LI-RADS) category is associated with the treatment outcomes of small single hepatocellular carcinoma (HCC) after surgical resection (SR) and radiofrequency ablation (RFA). Methods: This retrospective study included 357 patients who underwent SR (n = 209) or RFA (n = 148)...

Despite the therapeutic potential of recombinant proteins, their cell permeabilities and stabilities remain significant challenges. Here we demonstrate that cyclized recombinant proteins can be used as universal cargos for permeable and stable delivery into cells and polydiacetylene liposomes. Utilizing a split intein-mediated process, cyclized mod...

Objective: To compare therapeutic outcomes after liver transplantation (LT) between hepatocellular carcinomas (HCC) with low and high risk for microvascular invasion (MVI) within the Milan criteria evaluated preoperatively. Methods: Eighty patients with a single HCC who underwent LT as the initial therapy between 2008 and 2017 were included from...

Background: Patients with combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) are not traditionally considered eligible for liver transplantation (LT) due to poor outcomes. Aim: To compare outcomes between living donor LT (LDLT) patients with hepatocellular carcinoma (HCC) and LT patients with cHCC-CC and to identify risk factors...

A new triggered self-assembly method, which utilizes retro Diels-Alder (rDA)-promoted self-assembly of a macrocyclic diacetylene, was developed. The steric bulk present in a Diels-Alder (DA) adduct was released by a thermally promoted rDA reaction, resulting in the generation of a linear diacetylene that readily self-assembles to form a supramolecu...

Objective: To define benchmark values for adult-to-adult living-donor liver transplantation (LDLT). Background: LDLT utilizes living-donor hemiliver grafts to expand the donor pool and reduce waitlist mortality. While references have been established for donor hepatectomy, no such information exists for recipients to enable conclusive quality and...

Background: Pure laparoscopic donor right hepatectomy (PLDRH) is not yet a standardized surgical procedure due to lack of data. Objective: The aim was to identify safety and risk factors of living donor after PLRDH in a Korean multicenter cohort study. Methods: This retrospective study included 543 patients undergoing PLRDH between 2010 and 20...

There are very rare but definite situations where intraoperative abortions are inevitable in living-donor liver transplantation (LDLT) by unexpected or catastrophic events in the real world. This study aimed to summarize the cases of aborted LDLT and propose a strategy to prevent abortion or minimize donor damage from both recipient and donor sides...

Background: Poor sleep quality is common after liver transplantation, which lowers health-related quality of life. However, the detection and management of sleeping difficulties in liver transplant recipients have been limited. Purpose: This study was designed to assess sleep quality in liver transplant recipients in Korea and associated factors...

Background: This study aimed to evaluate recurrence-free survival (RFS) and overall survival (OS) after liver transplantation (LT) or liver resection (LR) for hepatocellular carcinoma (HCC) and perform subgroup analysis for HCC with high-risk imaging findings for recurrence on preoperative liver magnetic resonance imaging (MRI; high-risk MRI featu...