Jonathan Sicsic

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Verified

Jonathan verified their affiliation via an institutional email.

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• PhD
• Professor (Associate) at Université Paris Cité

Background The capacity of the 7C model’s psychological antecedents, which include confidence in vaccines, complacency, convenience, calculation, collective responsibility, confidence in the wider system, and social conformism, to explain variance in COVID-19 vaccine intentions and behaviours has been documented. However, it remains unclear whether...

Introduction Human Papillomavirus (HPV) vaccine uptake in the French Caribbean has remained below 25% since introduction in 2007, which is well behind national and international targets. Using a discrete choice experiment (DCE), we explored parental preferences around HPV vaccination and optimized communication content in a sample of parents of mid...

Background We explored preferences around the benefit-risk ratio (BRR) of vaccination among the general adult population and health care sector workers (HCSWs). We estimated preference weights and expected vaccine uptake for different BRR levels for a vaccine recommended during an infectious disease emergence. In addition, we explored how far quali...

Fondo: En Francia, la aceptación de la vacuna contra el VPH recomendada sigue siendo baja. La vacuna no puede ser administrada sin el consentimiento de los padres, pero los estudios han demostrado que los adolescentes son capaces de tomar decisiones informadas sobre su salud. Nuestro objetivo fue comprender el peso de la intención de vacunación de...

Human Papillomavirus (HPV) vaccine coverage was <50% in France in 2022 and even lower among socially disadvantaged populations. We aimed to evaluate socio-demographic determinants of HPV vaccine awareness, uptake, and intention among parents of adolescents, and related attitudes and knowledge items. Parents of adolescents attending middle schools a...

With the aim to optimize communication during HPV vaccination campaigns in France, we elicited parental preferences around HPV vaccination. We conducted a single-profile discrete choice experiment (DCE) among parents of 11- to 14-year-old middle-school pupils, who completed an anonymous, self-administered, internet-based questionnaire during 2020–2...

Background Widely documented psychological antecedents of vaccination are confidence in vaccines, complacency, convenience, calculation, collective responsibility (5C model) with the recent addition of confidence in the wider system and social conformism. While the capacity of these seven antecedents (7C) to explain variance in COVID-19 vaccine int...

Background In France, human papillomavirus (HPV) vaccination coverage varies across socioeconomic levels. Aim We aimed at assessing HPV vaccine awareness, uptake and vaccination intention among adolescents in France. Methods In a cluster-randomised study, 13–15-year-old students in 61 French middle schools completed a web-based questionnaire. We...

Support for vaccine decision-making requires a tailored approach taking into account psychological antecedents of vaccine acceptance. We aimed at validating an extended 7C-model of antecedents in three different target population groups (healthcare workers [n = 3870], parents [n = 2002] and adolescents [n = 7118]) and two vaccinations (COVID-19, HP...

Background HPV vaccination is recommended in France for all adolescents aged 11-14. Coverage has increased over recent years but remains below 50% by age 15, with social disparities by area deprivation level, parental education and income. We analysed the effect of school-wide campaigns on adolescent vaccine uptake and related disparities. Methods...

Background The objective of healthy aging strategies is to support interventions targeting autonomy loss prevention, with the assumption that these interventions are likely to be efficient by simultaneously improving clinical outcomes and saving costs. Methods We compare the economic impact of two interventions targeting frailty prevention in olde...

Background Elimination of mother-to-child transmission of hepatitis B virus (HBV) requires infant immunoprophylaxis and antiviral prophylaxis for pregnant women with high viral loads. Since real-time polymerase chain reaction (RT-PCR), a gold standard for assessing antiviral eligibility, is neither accessible nor affordable for women living in low-...

Background: In August 2021, France enacted a COVID-19 certificate requirement (vaccination/recovery/test) to access specific services, with mandates for professional groups. We evaluated the impact of this incentive-coercive policy in terms of vaccine uptake equality, future vaccine intention and confidence in authorities' crisis management. Meth...

We introduce a new individual measure of healthy aging on a sample of more than 39,000 individuals and compare the results for France with 11 other European countries and the United States. Our healthy aging measure is based on the discrepancy between the calendar age of populations with their estimated physiological age, which corresponds to a mea...

Seasonal influenza vaccination rates remain low, and contribute to preventable influenza cases, hospitalizations, and deaths in the US. While numerous interventions have been implemented to increase vaccine uptake, there is a need to determine which interventions contribute most to vaccine willingness, particularly among age groups with vaccination...

Nursing home residents often are poly-medicated, which increases their risks of receiving potentially inappropriate medications. This problem has become a major public health issue in many countries, and in particular in France. Indeed, high uses of potentially inappropriate medication prescriptions can lead to adverse effects that are likely to in...

À partir d’une enquête originale menée fin novembre 2020, nous identifions les déterminants socio-démographiques et comportementaux d’adhésion aux mesures contre la Covid-19. Notre analyse porte sur l’acceptation du télétravail, les intentions de vaccination et la confiance dans la gestion de la crise par les autorités. Le goût pour les actions col...

Objectives Global comparisons and large samples are needed to inform policy makers about aging trends among people aged older than 60 years. Using harmonized data gathered from the Gateway to Global Aging data, we introduce a new framework to measure healthy aging across 13 OECD countries. Methods First, we developed an original measure of physiol...

Background There is a critical need to identify the drivers of willingness to receive new vaccines against emerging and epidemic diseases. A discrete choice experiment is the ideal approach to evaluating how individuals weigh multiple attributes simultaneously. We assessed the degree to which six attributes were associated with willingness to be va...

Background The MyPeBS study is an ongoing randomised controlled trial testing whether a risk-stratified breast cancer screening strategy is non-inferior, or eventually superior, to standard age-based screening at reducing incidence of stage 2 or more cancers. This large European Commission-funded initiative aims to include 85,000 women aged 40 to 7...

Little is known about care use decisions at the beginning of the disability process, when elderly people are vulnerable. This article investigates the impact of formal care (FC) consumption on informal care (IC) utilization in Europe in a population of frail elderly people. We use data from the Sarcopenia and Physical fRailty IN older people: multi...

Malgré l’absence de réforme du grand âge et de l’autonomie, le quinquennat qui s’achève a vu la réalisation de nombreuses actions, dont les plus importantes resteront les revalorisations salariales des métiers du grand âge et la création de la branche autonomie de la Sécurité sociale. On peut néanmoins regretter l’absence d’une stratégie globale po...

In this stated preferences study, we describe for the first time French citizens’ preferences for various epidemic control measures, to inform longer-term strategies and future epidemics. We used a discrete choice experiment in a representative sample of 908 adults in November 2020 (before vaccination was available) to quantify the trade-off they w...

Background We previously conducted a single-profile discrete choice experiment to elicit preferences of adolescents around HPV vaccine communication, finding that only half of participants made variable choices (non-uniform respondents) from which preferences were elicited. In this paper we provide a framework to evaluate post-choice certainty info...

Les métiers du grand âge sont au cœur des politiques du bien-vieillir des pays Européens. Les travailleurs du secteur apportent des soins en établissement et au domicile des personnes. Ces métiers sont pénibles et ont souvent un impact négatif sur la santé (fonctionnelle et mentale) des travailleurs. Si cet effet délétère des métiers du grand âge e...

This paper shows that prospect theory, extended to account for differences across individuals in their patience and their valuation of the vaccination as a common good can explain why more than 40% of the population has intent to reject the Covid-19 vaccination, as well as the differences in vaccination intentions across population subgroups. Indee...

Objectives To analyse preferences around promotion of COVID-19 vaccination among workers in the healthcare and welfare sector in Fance at the start of the vaccination campaign. Design Single-profile discrete-choice experiment. Respondents in three random blocks chose between accepting or rejecting eight hypothetical COVID-19 vaccination scenarios....

Like many OECD countries, Germany is currently facing a shortage of long-term care (LTC) workers. This situation is concerning in the context of the ageing of the German population. A potential reason why Germany fails to recruit and retain LTC workers is that LTC jobs are particularly demanding (physical and psychological strain) which may be harm...

In a context of population aging, providing assistance to frail older people and encouraging healthy aging have become policy priorities. A central question is related to the efficiency and people-centeredness of public policies. We show that indeed, there is a strong correlation between frail older people’s self-reported health and their long-term...

Background Human Papillomavirus (HPV) vaccine coverage in France is below 30%, despite proven effectiveness against HPV infections and (pre-)cancerous cervical lesions. To optimise vaccine promotion among adolescents, we used a discrete choice experiment (DCE) to identify optimal statements regarding a vaccination programme, including vaccine chara...

In this stated preferences study, we describe for the first time French citizens' preferences for various epidemic control measures, to inform longer-term strategies and future epidemics. We used a discrete choice experiment in a representative sample of 908 adults in November 2020 to quantify the trade-off they were willing to make between restric...

This paper explores the association between health measures and long-term care (LTC) use in the 70+ old population. We examine how different measures of health—subjective versus objective—predict LTC use, provided either formally or informally. We consider an absolute measure of subjective health, the grade given by the individual to his/her health...

This systematic literature review documents the link between frailty or sarcopenia, conceptualized as dimensions of physical health, and the use of long-term care services by older individuals. Long-term care services include formal and informal care provided at home as well as in institutions. A systematic review was performed according to PRISMA...

A partir d’une enquête originale, nous identifions les déterminants socio-démographiques et comportementaux d’adhésion aux mesures contre la COVID-19 : télétravail, intention d’accepter la vaccination et confiance aux autorités dans leur gestion de la crise. La coopération dans le jeu du bien public est fortement et significativement associée à la...

The individual determinants of vaccine acceptance among health workers (HCWs) have been described in the literature, but there is little evidence regarding the impact of vaccine characteristics and contextual factors (e.g., incentives, communication) on vaccination intentions. We developed a single profile discrete choice experiment (DCE) to assess...

Background: Healthcare workers (HCWs) are prioritised for COVID-19 vaccination. Analysing their vaccination preferences is crucial to understand suboptimal uptake and identify levers to increase acceptance among those hesitating. Methods: We administered an online single-profile discrete choice experiment among a snowballing sample of French HCWs,...

The long-term care (LTC) sector will soon face a shortage of care workers, which raises the needs for action. The consequences are potentially dramatic, urging the need to design policies aiming at reducing the turnover rate of LTC workers. Immigrant workers are an important part of the LTC workforce. Pooling data from the Annual Social and Economi...

Physical frailty and sarcopenia (PF&S) has received growing attention in empirical models of health care use. However, few articles focused on objective measures of PF&S to assess the extent of care consumption among the frail population at risk of dependency. Using baseline data from the SPRINTT study, a sample of 1,518 elderly people aged 70+ rec...

Background: Antidementia drugs (cholinesterase inhibitors and memantine) are still widely prescribed despite their controversial effects and 2011 guidelines that no longer encourage their prescription. The objective was to assess which factors remained determinants of antidementia drug prescriptions. Methods: A cross-sectional study was performe...

Objective: There is relative consensus that chronic conditions, disability, and time-to-death are key drivers of age-related health care expenditures. In this paper, we analyze the specific impact of frailty transitions on a wide range of health care outcomes comprising hospital, ambulatory care, and dental care use. Data source: Five regular wa...

Resource allocation decisions require information about individuals' preferences for goods and services. Survey based stated preference methods, such as discrete choice experiments (DCEs), are used to elicit preferences for non-market goods. A critique of stated preference research is that respondents to hypothetical surveys may not provide careful...

Discrete choice experiments (DCEs) are frequently used in health economics to measure preferences for nonmarket goods. Best–worst discrete choice experiment (BWDCE) has been proposed as a variant of the traditional “pick the best” approach. BWDCE, where participants choose the best and worst options, is argued to generate more precise preference es...

Introduction : Au cours de ces dix dernières années, la balance bénéfice-risque associée au dépistage du cancer du sein a été largement débattue. À ce jour, il n’existe cependant pas de données françaises interrogeant le point de vue des femmes et leurs préférences (au sens économique) vis-à-vis de ce dépistage, pourtant controversé. Méthodes : Un...

Introduction : Les médecins généralistes (MG) jouent un rôle clé dans l’offre de services de prévention et de dépistage ciblé, en particulier dans le cas des cancers du sein, du col de l’utérus et du côlon. Cependant, leur implication reste limitée et très variable selon les médecins et le type de cancer. En utilisant la méthodologie des choix disc...

Purpose Antibiotic prescription is a central public health issue. Overall, 90% of antibiotic prescriptions are delivered to patients in ambulatory care, and a substantial proportion of these prescriptions could be avoided. General Practitioner (GP) trainers are similar to other GPs in terms of sociodemographic and medical activities, but they may h...

Background The impact of adverse effects of drugs for dementia on the risk of hospitalization has not been much studied despite the impact of hospitalizations on cognitive decline. Objective To determine if the main adverse effects of cholinesterase inhibitors and memantine may be associated with excess of hospitalization and to quantify the subse...

Background Over the past decade, the benefits and harms balance of breast cancer (BC) screening has been widely debated. Objectives To elicit women’s trade-offs between the benefits and harms of BC screening and to analyze the main determinants of these trade-offs. Methods A discrete choice experiment with seven attributes depicting BC screening...

Background: Since the 2011 French guidance updates, cholinesterase inhibitors and memantine are considered optional in the management of dementia and leave physicians free to prescribe based on their clinical expertise. Objectives: The aims of this study were to analyze the influence of these recent guidance updates on the prescription rates of...

Background A voluntary-based pay-for-performance (P4P) program (the CAPI) aimed at general practitioners (GPs) was implemented in France in 2009. The program targeted prevention practices, including breast cancer screening, by offering a maximal amount of €245 for achieving a target screening rate among eligible women enrolled with the GP. Objectiv...

Pay-for-performance (P4P) has been increasingly used across different healthcare settings to incentivize the provision of targeted services. In this study, we investigated the effect of a nationwide P4P scheme for general practitioners implemented in 2012 in France, on cervical cancer screening practices. Using data from a nationally representative...

BACKGROUND: Early diagnosis of HIV infection is a major public health issue worldwide. In 2009, the French National Authority for Health (Haute Autorité de Santé) developed specific guidelines and recommended mass screening of 15-70-year-olds across the general population. The guidelines were supported by communication directed at healthcare profes...

General practitioners (GPs) play a key role in the delivery of preventive and screening services for breast, cervical, and colorectal cancers. In practice, GPs' involvement varies considerably across types of cancer and among GPs, raising important questions about the determinants of GPs' implication in screening activities: what is the relative im...

There is evidence of social disparities in the use of primary health services in most European countries, and these disparities particularly affect people with disabilities. Many determinants of disabilities interact to limit access to health care (e.g. impairments, functional limitations, educational level). However, these determinants have typica...

The CAPI (contract for improving professional practices) is a voluntary pay for performance scheme for primary care physicians introduced in France in 2009. Our objective was to analyze general practitioners’ (GPs) perceptions of the impact of the CAPI on their healthcare practices.

This thesis addresses several issues raised by the introduction in France of economic incentives such as pay-For-Performance applied to general practice. These incentive schemes are designed to improve the quality of care, but they are discussed both in terms of effectiveness and potential side effects. Initially, we assess the impact of the CAPI s...

In 2009, a voluntary-based pay for performance scheme targeting general practitioners (GPs) was introduced in France through the 'Contract for Improving Individual Practices' (CAPI). To study the impact of the CAPI on French GPs' consultation length. Univariate analysis, and multilevel regression analyses were performed to disentangle the different...

Background In France, equality in access to screening has been one of the main thrusts of public policies implemented between 2009 and 2013 (the national cancer plan). Our aim in this study was to analyse the obstacles to and levers for breast, cervical, and colorectal cancer screening uptake and their trends over time. Methods Based on representa...

Objectives We aimed to disentangle the effects of obesity and mobility limitation on cervical and breast cancer screening among community dwelling women. Methods The data source was the French national Health and Disability Survey - Household Section, 2008. The Body Mass Index (BMI) was used to categorize obesity status. We constructed a continuou...

/st>Pay-for-performance programmes have been widely implemented in primary care, but few studies have investigated their potential adverse effects on the intrinsic motivation of general practitioners (GPs) even though intrinsic motivation may be a key determinant of quality in health care. Our aim was to compare methods for developing a composite s...

In 2009, a voluntary pay for performance (P4P) scheme for primary care physicians was introduced in France through the 'Contract for Improving Individual Practice' (CAPI). Although the contract could be interrupted at any time and without any penalty, two-thirds of French general practitioners chose not to participate. We studied what factors motiv...

Background: Like many other OECD nations, France has implemented a pay-for-performance (P4P) model in primary care. However, the benefits have been debated, particularly regarding the possibly undesirable effects of extrinsic motivation (EM) on intrinsic motivation (IM). Objective: To examine the relationship between French GPs' IM and EM based...