Joliot Marc

Joliot Marc
Atomic Energy and Alternative Energies Commission | CEA · UMR 5293 IMN GIN (Neurofunctional imaging group)

PhD, HDR

About

142
Publications
36,039
Reads
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20,718
Citations
Citations since 2017
50 Research Items
10411 Citations
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201720182019202020212022202305001,0001,500
201720182019202020212022202305001,0001,500
Introduction
Resting-state, MRI, functional MRI, imaging , atlasing, cognition, deep-learning
Additional affiliations
January 2011 - present
January 2007 - present
French National Centre for Scientific Research
Position
  • Centre national de la recherche scientifique
January 2005 - December 2007

Publications

Publications (142)
Article
Full-text available
Is ongoing conscious thought spontaneous and situation-related, or is it recurrent and dependent on psychological dispositions? The answer is critical for resting-state functional connectivity (RSFC) paradigms that seek to correlate neuroanatomical states with conscious mental states. The goal of the present study was to characterize individual res...
Article
Full-text available
It has been suggested that engraved abstract patterns dating from the Middle and Lower Palaeolithic served as means of representation and communication. Identifying the brain regions involved in visual processing of these engravings can provide insights into their function. In this study, brain activity was measured during perception of the earlies...
Preprint
Full-text available
Over the past two decades, the study of resting-state functional magnetic resonance imaging (fMRI) has revealed the existence of multiple brain areas displaying synchronous functional blood oxygen level-dependent signals (BOLD)-resting-state networks (RSNs). The variation in functional connectivity between the different areas of a resting-state net...
Preprint
Full-text available
It has been suggested that engraved abstract patterns dating from the Middle and Lower Palaeolithic served as means of representation and communication. Identifying the brain regions involved in visual processing of these engravings can provide insights into their function. In this study, brain activity was measured during perception of the earlies...
Article
Full-text available
Significance Left-handedness occurs in roughly 10% of people, but whether it involves altered brain anatomy has remained unclear. We measured left to right asymmetry of the cerebral cortex in 28,802 right-handers and 3,062 left-handers. There were small average differences between the two handedness groups in brain regions important for hand contro...
Article
Full-text available
Functional connectivity analyses of fMRI data have shown that the activity of the brain at rest is spatially organized into resting-state networks (RSNs). RSNs appear as groups of anatomically distant but functionally tightly connected brain regions. Inter-RSN intrinsic connectivity analyses may provide an optimal spatial level of integration to an...
Article
Full-text available
Left–right hemispheric asymmetry is an important aspect of healthy brain organization for many functions including language, and it can be altered in cognitive and psychiatric disorders. No mechanism has yet been identified for establishing the human brain’s left–right axis. We performed multivariate genome-wide association scanning of cortical reg...
Article
Full-text available
We report on MRi-Share, a multi-modal brain MRI database acquired in a unique sample of 1870 young healthy adults, aged 18–35 years, while undergoing university-level education. MRi-Share contains structural (T1 and FLAIR), diffusion (multispectral), susceptibility-weighted (SWI), and resting-state functional imaging modalities. Here, we described...
Article
Full-text available
The relationship between hippocampal subfield volumetry and verbal list-learning test outcomes have mostly been studied in clinical and elderly populations, and remain controversial. For the first time, we characterized a relationship between verbal list-learning test outcomes and hippocampal subfield volumetry on two large separate datasets of 447...
Preprint
Full-text available
Roughly 10% of the human population is left-handed, and this rate is increased in some brain-related disorders. The neuroanatomical correlates of hand preference have remained equivocal. We re-sampled structural brain image data from 28,802 right-handers and 3,062 left-handers (UK Biobank population dataset) to a symmetrical surface template, and m...
Article
Full-text available
We implemented a deep learning (DL) algorithm for the 3-dimensional segmentation of perivascular spaces (PVSs) in deep white matter (DWM) and basal ganglia (BG). This algorithm is based on an autoencoder and a U-shaped network (U-net), and was trained and tested using T1-weighted magnetic resonance imaging (MRI) data from a large database of 1,832...
Article
Full-text available
The human cerebral hemispheres show a left-right asymmetrical torque pattern, which has been claimed to be absent in chimpanzees. The functional significance and developmental mechanisms are unknown. Here, we carried out the largest-ever analysis of global brain shape asymmetry in magnetic resonance imaging data. Three population datasets were used...
Preprint
Full-text available
We implemented a deep learning (DL) algorithm for the 3-dimensional segmentation of perivascular spaces (PVSs) in deep white matter (DWM) and basal ganglia (BG). This algorithm is based on an autoencoder and a U-shaped network (U-net), and was trained and tested using T1-weighted magnetic resonance imaging (MRI) data from a large database of 1,832...
Article
Full-text available
Currently, several human brain functional atlases are used to define the spatial constituents of the resting-state networks (RSNs). However, the only brain atlases available are derived from samples of young adults. As brain networks are continuously reconfigured throughout life, the lack of brain atlases derived from older populations may inf luen...
Article
Full-text available
Based on the joint investigation in 287 healthy volunteers (150 left-Handers (LH)) of language task-induced asymmetries and intrinsic connectivity strength of the sentence-processing supramodal network, we show that individuals with atypical rightward language lateralization (N = 30, 25 LH) do not rely on an organization that simply mirrors that of...
Article
Full-text available
Based on the joint investigation in 287 healthy volunteers (150 left-Handers (LH)) of language task-induced asymmetries and intrinsic connectivity strength of the sentence-processing supramodal network, we show that individuals with atypical rightward language lateralization (N = 30, 25 LH) do not rely on an organization that simply mirrors that of...
Article
Full-text available
Based on the joint investigation in 287 healthy volunteers (150 Left-Handers (LH)) of language task-induced asymmetries and intrinsic connectivity strength of the sentence-processing supramodal network, we show that individuals with atypical rightward language lateralization (N = 30, 25 LH) do not rely on an organization that simply mirrors that of...
Preprint
Full-text available
Currently, several human brain functional atlases are used to define the spatial constituents of the resting-state networks (RSNs). However, the only brain atlases available are derived from samples of young adults. As brain networks are continuously reconfigured throughout life, the lack of brain atlases derived from older populations may influenc...
Preprint
Full-text available
Functional connectivity analyses of fMRI data have shown that the activity of the brain at rest is spatially organized into resting-state networks (RSNs). RSNs appear as groups of anatomically distant but functionally tightly connected brain regions. Inter-RSN intrinsic connectivity analyses may provide an optimal spatial level of integration to an...
Preprint
Left-right hemispheric asymmetry is an important aspect of healthy brain organization for many functions including language, and can be altered in cognitive and psychiatric disorders1-8. No mechanism has yet been identified for establishing the human brain's left-right axis9. We performed multivariate genome-wide association scanning (mvGWAS) of co...
Preprint
We report on MRi-Share, a multi-modal brain MRI database acquired in a unique sample of 1,870 young healthy adults, aged 18 to 35 years, while undergoing university-level education. MRi-Share contains structural (T1 and FLAIR), diffusion (multispectral), susceptibility weighted (SWI), and resting-state functional imaging modalities. Here, we descri...
Preprint
Full-text available
We applied a multitask multimodal hierarchical classification (MMHC) to 287 volunteers (150 left-handers) to establish different brain language hemispheric dominance patterns (LangDom). MMHC was based on inter- and intrahemispheric measures of the sentence core network (SENT_CORE): 1) task-induced asymmetries (ACTIV) while listening to, reading, an...
Article
A pivotal question in modern neuroscience is which genes regulate brain circuits that underlie cognitive functions. However, the field is still in its infancy. Here we report an integrated investigation of the high-level language network (i.e., sentence processing network) in the human cerebral cortex, combining regional gene expression profiles, t...
Article
Full-text available
We aimed at identifying plurimodal large-scale networks for producing, listening to and reading word lists based on the combined analyses of task-induced activation and resting-state intrinsic connectivity in 144 healthy right-handers. In the first step, we identified the regions in each hemisphere showing joint activation and joint asymmetry durin...
Preprint
Full-text available
The average human brain is characterized by a global left-right asymmetry of shape, including a well-known 'torque' on the fronto-occipital axis, and less-studied differences on the dorsal-ventral axis. Torque has been claimed to be human-specific. However, the functional significance and developmental mechanisms underlying the global aspects of br...
Article
Following a first version AAL of the automated anatomical labeling atlas (Tzourio-Mazoyer et al., 2002), a second version (AAL2) (Rolls et al., 2015) was developed that provided an alternative parcellation of the orbitofrontal cortex following the description provided by Chiavaras, Petrides, and colleagues. We now provide a third version, AAL3, whi...
Article
Full-text available
The earliest human graphic productions, consisting of abstract patterns engraved on a variety of media, date to the Lower and Middle Palaeolithic. They are associated with anatomically modern and archaic hominins. The nature and significance of these engravings are still under question. To address this issue, we used functional magnetic resonance i...
Conference Paper
Full-text available
We propose two methodologies to better understand the inter-individual variability of functional Magnetic Resonance Imaging brain data. The aim is to quantify whether the “average” dendrogram is representative of the initial population and to identify its possible sources of instability. The first method identifies networks that can lead to unstabl...
Preprint
Full-text available
Even if speech perception and production have been revealed to share a common recruitment of both discrete auditory and motor areas, this overlap being also common to reading and listening, no study has investi- gated the involvement of larger networks in the three tasks yet. So, we first identified the multimodal bilateral brain areas conjointly a...
Preprint
Full-text available
We propose two methodologies in order to better understand the inter-individual variability of resting-state functional Magnetic Resonance Imag- ing (fMRI) brain data. The aim of the study was to quantify whether the average dendrogram is representative of the initial population and to identify its possible sources of instability. The average dendr...
Article
Full-text available
With the advances in diffusion MRI and tractography, numerous atlases of the human pyramidal tract (PyT) have been proposed, but the inherent limitation of tractography to resolve crossing bundles within the centrum semiovale has so far prevented the complete description of the most lateral PyT projections. Here, we combined a precise manual positi...
Article
Full-text available
We herein propose an atlas of 32 sentence-related areas based on a 3-step method combining the analysis of activation and asymmetry during multiple language tasks with hierarchical clustering of resting-state connectivity and graph analyses. 144 healthy right-handers performed fMRI runs based on language production, reading and listening, both with...
Preprint
Full-text available
The earliest human graphic productions dating to the Lower and Middle Palaeolithic are associated with anatomically modern and archaic hominins. These productions, which consist of abstract patterns engraved on a variety of media, may have been used as symbols, and their emergence is thought to be associated with the evolution of the properties of...
Preprint
Full-text available
A pivotal question in modern neuroscience is which genes regulate brain circuits that underlie cognitive functions. However, the field is still in its infancy. Here we report an integrated investigation of the high-level language network (i.e., sentence processing network) in the human cerebral cortex, combining regional gene expression profiles, t...
Preprint
With the advances in diffusion MRI and tractography, numerous atlases of the human pyramidal tract (PyT) have been proposed but the inherent limitation of tractography to resolve crossing bundles within the centrum semiovale have so far prevented the complete description of the most lateral PyT projections. Here, we combined a precise manual positi...
Chapter
Information Systems, used to share information, lead to the growth of heterogeneous data and then the dependencies between them. Thus, the links and dependencies among heterogeneous and distributed data are more and more complex during daily activities of users (researchers, engineers, etc.). Our contribution is to propose a methodology to facilita...
Preprint
Full-text available
We herein propose an atlas of 32 sentence-related areas based on a 3-step method combining the analysis of activation and asymmetry during multiple language tasks with hierarchical clustering of resting-state connectivity and graph analyses. 144 healthy right-handers performed fMRI runs based on language production, reading and listening, both with...
Article
We used a Support Vector Machine (SVM) classifier to assess hemispheric pattern of language dominance of 47 individuals categorized as non-typical for language from their hemispheric functional laterality index (HFLI) measured on a sentence minus word-list production fMRI-BOLD contrast map. The SVM classifier was trained at discriminating between D...
Article
Full-text available
Despite its significant functional and clinical interest, the anatomy of the uncinate fasciculus (UF) has received little attention. It is known as a ‘hook-shaped’ fascicle connecting the frontal and anterior temporal lobes and is believed to consist of multiple subcomponents. However, the knowledge of its precise connectional anatomy in humans is...
Article
Full-text available
The dysconnectivity theory of schizophrenia proposes that schizophrenia symptoms arise from abnormalities in neuronal synchrony. Resting-state Functional Connectivity (FC) techniques allow us to highlight synchronization of large-scale networks, the Resting-state Networks (RNs). A large body of work suggests that disruption of RN synchronization co...
Article
Introduction i-Share (internet–based Student Heath REsSaC) est la premiere enquete epidemiologique d’envergure (n = 30 000) sur la sante des etudiants. L’acquisition d’une IRM cerebrale multimodale est en cours dans une partie de la cohorte (n = 2000), afin d’etudier la maturation cerebrale post-adolescence (18–35 ans), en particulier l’impact des...
Article
Full-text available
The data management needs of the neuroimaging community are currently addressed by several specialized software platforms, which automate repetitive data import, archiving and processing tasks. The BIOMedical Imaging SemanTic data management (BIOMIST) project aims at creating such a framework, yet with a radically different approach: the key insigh...
Article
Full-text available
Major advances in resting-state functional magnetic resonance imaging (fMRI) techniques in the last two decades have provided a tool to better understand the functional organization of the brain both in health and illness. Despite such developments, characterizing regulation and cerebral representation of mind wandering, which occurs unavoidably du...
Article
The amount of heterogeneous information that researchers in bio-medical imaging (BMI) field have to manage has grown significantly, and their costs remain high. Large-scale sharing and reusing of this information has become unavoidable. Some data management systems have been developed in neuroimaging field, however they miss to integrate the data p...
Article
Full-text available
Information Systems, used to share information, lead to the growth of heterogeneous data and then the dependencies between them. Thus, the links and dependencies among heterogeneous and distributed data are more and more complex during daily activities of users (engineers, researchers, etc.). Ontology is currently used to enhance the knowledge shar...
Article
Full-text available
The aim of this study was to characterize, using fMRI, the functional asymmetries of hand laterality task (HLT) in a sample of 295 participants balanced for handedness. During HLT, participants have to decide whether the displayed picture of a hand represent a right or a left hand. Pictures of hands’ back view were presented for 150 ms in the right...
Conference Paper
Full-text available
The emergence of PLM for biomedical imaging lifecycle management highlights the needs for management and analysis of heterogeneous, complex and multidimensional data in PLM systems. Data provenance in biomedical imaging domain is complex, notably provenance of processing data, and to ensure full traceability in a purpose of reuse, processing operat...
Article
Full-text available
We combined the neuroanatomists' approach of defining a fascicle as all fibers passing through its compact stem with diffusion-weighted tractography to investigate the cortical terminations of two association tracts, the inferior fronto-occipital fasciculus (IFOF) and the uncinate fasciculus (UF), which have recently been implicated in the ventral...
Article
Asymmetry in intra-hemispheric intrinsic connectivity, and its association with handedness and hemispheric dominance for language, were investigated in a sample of 290 healthy volunteers enriched in left-handers (52.7%). From the resting-state FMRI data of each participant, we derived an intra-hemispheric intrinsic connectivity asymmetry (HICA) mat...
Article
We investigated the regional correlates of differences in hemispheric lateralization in 297 healthy volunteers [including 153 left-handers (LH)] previously classified into three types of language lateralization according to their hemispheric functional lateralization index measured with fMRI during covert sentence production versus word list produc...
Article
We report on a database, named BIL&GIN, designed for investigating the cognitive, behavioral, genetic, and brain morphological/functional correlates of hemispheric specialization. The database contains records from a sample of 453 adult participants enriched in left-handers (45%, N=205) as compared to the general population. For each subject, socio...