John Mina

John Mina
Teesside University · School of Science Engineering and Design

25.27
 · 
BPharm(Hons) MSc PhD Chem. Biol. MRSC AFHEA AMISTR

About

31
Publications
2,182
Reads
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257
Citations
Introduction
Skills and Expertise
Lipids
Chemical Biology
Protozoa
Trypanosoma
Parasitic Diseases
Molecular Parasitology
Tropical Diseases
Leishmania

Publications

Publications (31)
Exploring Leishmania major Inositol Phosphorylceramide Synthase (LmjIPCS): Insights into the ceramide binding domain
Article
Full-text available
  • Mar 2011
A plate-based assay system for analyses and screening of the Leishmania major inositol phosphorylceramide synthase
Article
  • Sep 2010
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target
Article
Full-text available
  • Jul 2009
Y Functional analyses of differentially expressed isoforms of the Arabidopsis inositol phosphorylceramide synthase
Article
Full-text available
  • Jul 2010
A Tandem C—H Insertion—Acetal Cleavage Sequence: Stereocontrolled Synthesis of Substituted Tetrahydrofurans.
Article
  • Oct 2005
The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity
Article
Full-text available
  • May 2019
Ceramides bind VDAC2 to trigger mitochondrial apoptosis
Article
Full-text available
  • Apr 2019
Supplementary Material 7
Data
  • Apr 2019
Supplementary Material 1
Data
  • Apr 2019
Supplementary Material 3
Data
  • Apr 2019
Supplementary Material 6
Data
  • Apr 2019
Supplementary Material 2
Data
  • Apr 2019
Supplementary Material 4
Data
  • Apr 2019
Supplementary Material 5
Data
  • Apr 2019
Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform
Article
Full-text available
  • Dec 2018
Supplementary data
Data
  • Oct 2018
Data Profile
Data
  • Oct 2018
Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania
Article
Full-text available
  • Oct 2018
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Article
Full-text available
  • Jan 2018
Supplemental Data
Data
  • Jul 2017
Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis
Article
Full-text available
  • Jun 2017
Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites
Article
Full-text available
  • Jun 2017
Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases
Article
Full-text available
  • Mar 2017
ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
Article
Full-text available
  • Jan 2017
Supplementary Information
Data
  • Jan 2017
Switching Head Group Selectivity in Mammalian Sphingolipid Biosynthesis by Active-site-engineering of Sphingomyelin Synthases
Article
Full-text available
  • May 2016
Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
Data
Full-text available
  • Jan 2013
Functional analyses of differentially expressed isoforms of the Arabidopsis Inositol phosphorylceramide synthase
Data
Full-text available
  • Jan 2013
Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
Article
Full-text available
  • Dec 2012
Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets
Article
Full-text available
  • Feb 2012
The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target
Article
  • Nov 2009

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