John M Reid

John M Reid
NHS Grampian | National Health Service · Neurology

Doctor of Philosophy

About

38
Publications
6,950
Reads
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822
Citations
Citations since 2017
5 Research Items
428 Citations
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2017201820192020202120222023020406080
2017201820192020202120222023020406080
2017201820192020202120222023020406080
Introduction
Skills and Expertise

Publications

Publications (38)
Article
Full-text available
Background Mortality remains a substantial problem after acute ischemic stroke, despite advances in acute stroke treatment over the past three decades. Mortality is particularly high among patients with Total Anterior Circulation Stroke (TACS), generally representing patients with middle cerebral artery occlusions. Notably however, these patients a...
Article
Full-text available
Background: Haemolacria is a rare condition not previously associated with migraine with aura. We report the first such case and speculate as to a possible cause. Case: A 47 year old lady presented with repeated attacks of migraine with visual aura, ipsilateral sensory symptoms, and at times associated with ipsilateral haemolacria and significantly...
Article
Full-text available
Background: Thrombolysis for acute ischaemic stroke (AIS) patients aged ˜80 years is evidence based, although its use in previously dependent patients is controversial. Methods: Data from 831 thrombolysed AIS patients in our centre from 2009-2017 were used to compare demographic trends and outcomes (haemorrhage, mortality, three-month independen...
Article
Full-text available
Objective: The Clock Drawing Test (CDT) is commonly used as a screening tool for the assessment of dementia. The association between the CDT in acute stroke and long-term functional and cognitive outcomes in this population is unknown. The present prospective study is the first to examine if CDT scores in the acute stage after stroke are related t...
Article
Full-text available
Cite this article: Clarke R, Bagchi A, Rana A, Tyagi V, Reid JM. Three cases of vomiting-associated cervical artery dissection. Abstract Extracranial Cervical Arterial Dissection (CAD) affects 10-25% of young onset Acute Ischaemic Stroke (AIS) patients. We report three cases of CAD in young AIS patients (ages 14, 18 and 49) associated with prior vo...
Article
Introduction: physicians are often asked to prognosticate soon after a patient presents with stroke. This study aimed to compare two outcome prediction scores (Five Simple Variables [FSV] score and the PLAN [Preadmission comorbidities, Level of consciousness, Age, and focal Neurologic deficit]) with informal prediction by physicians. Methods: de...
Article
Full-text available
Disappearance of the hyperdense middle cerebral artery sign (HMCAS) following intravenous thrombolysis for ischaemic stroke is associated with improved outcome. Debate exists over which radiological thrombus characteristics can predict disappearance of the HMCAS after thrombolysis such as vessel attenuation or extent of thrombus length. Methods Is...
Article
Full-text available
Intravenous thrombolysis increases disability-free survival after acute ischaemic stroke in a time-dependent fashion. We aimed to determine whether pre-hospital notification, introduction of a CT scanner near to assessment site and introduction of out-of-hours thrombolysis services affect thrombolysis timing. Methods Timings related to thrombolysi...
Article
Full-text available
Neuromyelitis optica typically presents at a median age of 40-50 years. The myelitis is usually of acute onset, long (>3 vertebral segments) and causes severe sensorimotor and bladder and bowel disturbances. We describe a 73-year-old Caucasian woman with aquaporin-4 antibody-positive neuromyelitis optica whose index event was intermittent paroxysma...
Article
Full-text available
Symptomatic intracerebral haemorrhage following thrombolysis for ischaemic stroke causes significant morbidity and mortality. This study assessed which of four risk scores (SEDAN, HAT, GRASPS and SITS) best predicts symptomatic intracerebral haemorrhage. Data from 431 patients treated at Aberdeen Royal Infirmary (2003-2013) were extracted from a th...
Article
Full-text available
There are many relative contraindications to administering intravenous thrombolysis (IVT) for acute ischemic stroke (AIS), such as rapidly improving symptoms. In addition there has been debate about whether certain stroke subtypes are less likely to respond to IVT (e.g. lacunar stroke). We describe a case with consent of a 63 year old man with Caps...
Article
Full-text available
Background Extracranial carotid and vertebral artery dissection is an important cause of stroke, especially in young people. In some observational studies it has been associated with a high risk of recurrent stroke. Both antiplatelet drugs and anticoagulant drugs are used to reduce risk of stroke but whether one treatment strategy is more effective...
Article
IntroductionDebate exists as to whether wake-up stroke (WUS) (i.e. symptoms first noted on waking) differs from stroke developing while awake [awake onset stroke (AOS)]. Unknown onset stroke (UOS) with unclear symptom onset time is infrequently studied.AimsThis study aimed to examine differences in stroke characteristics and outcomes in these three...
Article
Full-text available
Background: Predicting outcome after stroke may have utility in providing prognostic information to patients and relatives, and informing treatment decisions. We aimed to develop predictive risk scores derived from outcome prediction models for outcomes 6 months post-stroke. Methods: The Stroke Outcome Study (2001-2) enrolled 538 ischaemic and haem...
Article
Full-text available
We present the case of a patient who developed periorbital ecchymosis (panda sign) following an exacerbation of asthma with severe coughing. There was no history of cranial trauma. Investigations for a structural or haematological cause were negative. The panda sign is typically seen following a base of skull fracture, but rarely reported due to se...
Conference Paper
Introduction: Many hospitals struggle to reduce the door to needle time for thrombolysis of stroke patients. In Scotland the target is treatment within 60 minutes of symptom onset. In order to achieve this goal one must create a smooth pathway between patient notication, A&E, scan- ning and administration of thrombolysis. We analysed data from our...
Article
Full-text available
A significant proportion of patients presenting to hyperacute stroke units (HSUs) are diagnosed with non-stroke (NS). This study aimed to assess the rate and diagnoses of NS patients admitted to a HSU and the implications for clinical service provision. Admissions to the HSU at the Southern General Hospital, Glasgow, were retrospectively assessed (...
Article
Congenital abnormalities of the internal carotid artery (ICA) are infrequent and can be associated with aberrations of the Circle of Willis. A 47-year-old gentleman presented with transient neurological symptoms and cerebral infarction and carotid Doppler showed a stenotic right ICA. Subsequent computed tomographic angiography showed a hypoplastic...
Article
Full-text available
To present the results of the nonrandomized arm of the Cervical Artery Dissection in Stroke Study (CADISS-NR) trial, comparing anticoagulation and antiplatelets for prevention of recurrent stroke after carotid and vertebral dissection, and perform a meta-analysis of these results with previously published studies comparing the 2 therapeutic strateg...
Article
Full-text available
BACKGROUND AND PURPOSE: Intracranial haemorrhage in neurosarcoidosis (NS-ICH) is rare, poorly understood and the diagnosis of NS may not be immediately apparent. METHODS: The clinical features of three new NS-ICH cases are described including new neuropathological findings and collated with cases from a systematic literature review. RESULTS: Cases:...
Article
Full-text available
models to predict functional status post-stroke have utility in balancing groups in randomised trials, for outcome comparison between stroke centres and may assist in outcome prediction. This study aimed to develop models of both excellent [modified Rankin score (mRS) 0-1] and devastating outcomes (mRS of 5-6). patients admitted with ischaemic or h...
Article
Full-text available
we aimed to assess whether the performance of stroke outcome models comprising simple clinical variables could be improved by the addition of more complex clinical variables and information from the first computed tomography (CT) scan. 538 consecutive acute ischaemic and haemorrhagic stroke patients were enrolled in a Stroke Outcome Study between 2...
Article
Full-text available
The syndrome of limbic encephalitis (LE) associated with antibodies against voltage-gated potassium channels (VGKC-LE) has recently been described. The number of published cases is however small. We therefore aimed to review all cases seen at our centre and compare with published cases. Retrospective cases of VGKC-LE were identified using a questio...
Article
Full-text available
Intrigued by the recent assertion that the “ice-on-eyes” test is 100% specific for myasthenia gravis,1–3 we performed this test in a patient presenting with partial ophthalmoplegia and unilateral ptosis due to Miller Fisher syndrome. This was a 24-year-old female who developed a diarrhoeal illness lasting several days. A right ptosis developed 10 d...
Article
Studies suggest that women with stroke are investigated less aggressively and receive tissue plasminogen activator less frequently than men. We tested whether gender differences in the investigation, treatment, and outcome of stroke are due to confounding factors. Gender differences in the use of investigations, trial enrollment, treatment with int...
Article
Full-text available
This report is of an atypical case of neuralgic amyotrophy with a Horner's syndrome, bilateral brachial plexus, lumbar plexus and phrenic nerve involvement. The diagnosis isconfirmed based on a classical history and examination findings with typical neurophysiological investigations for this condition. This report also highlights the novel use of p...
Article
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We aimed to validate a previously described six simple variable (SSV) model that was developed from acute and sub-acute stroke patients in our population that included hyper-acute stroke patients. A Stroke Outcome Study enrolled patients from 2001 to 2002. Functional status was assessed at 6 months using the modified Rankin Scale (mRS). SSV model p...
Article
Full-text available
Randomized trials demonstrate that intravenous tissue plasminogen activator (tPA) improves outcome in acute ischemic stroke (AIS). To assess translation of this efficacy into effectiveness in routine clinical practice we performed a case-control study of tPA treatment for AIS in a single hospital. 151 tPA-treated AIS patients (1996-2005) were match...
Article
Full-text available
We describe the case of a male patient who presented with mononeuritis multiplex due to polyarteritis nodosa following recent hepatitis B infection. Despite immunomodulatory treatment, the condition progressed with renal and small bowel involvement and the patient died. This case illustrates the difficulty in treating this multisystem disorder and...
Article
We aimed to study the timing of aspirin prescription in ischaemic stroke comparing patients admitted to an acute stroke unit (ASU) directly or via a general medical ward. We also analysed prescription of secondary preventive therapies in stroke patients in an ASU. Retrospective analysis was made of medical notes and prescription records of 69 patie...

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