John Radke

John Radke
BioResearch Associates, Inc. · Research

Master of Business Administration

About

101
Publications
23,567
Reads
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1,262
Citations
Citations since 2016
62 Research Items
824 Citations
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
Introduction
My greatest interest is in masticatory function, using technology to differentiate between normal function and the many types of dysfunction and finding treatment solutions that can correct the various dysfunctions. Masticatory function is best described by recording jaw motion and muscle activity simultaneously. When the occlusion is the primary cause of dysfunction, the T-Scan can reveal where the excessively forceful contacts are located. Our current efforts are focused on discovering the real relationships between the physical parameters leading to dysfunction and the emotional factors secondary to them.
Additional affiliations
May 2014 - present
BioResearch Associates Inc.
Position
  • CEO
Description
  • Developing plans and organizing research studies.
May 1996 - May 2014
BioResearch Associates Inc.
Position
  • CEO
Description
  • Administration of the business
September 1983 - May 1996
BioResearch Associates Inc.
Position
  • Vice President
Description
  • Research and development electronic and software-based diagnostic products

Publications

Publications (101)
Article
Full-text available
Objective: Diagnosing and effectively treating Meniere's Disease (MD) remains a significant challenge. There exists no consensus on the etiology in the literature. The purpose of this study was to treat patients diagnosed with MD utilizing the T-Scan Novus and BioEMG III to guide measured occlusal corrections in bite force and timing. The null hypo...
Article
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In a typical case of TMJ internal derangement the disk is displaced anteriorly, antero-medially or medially. If it reduces, it does so with a large vibration during the opening movement and then the disc re-displaces with a less intense or minimal vibration on closing. Occasionally, this scenario is altered such that the opening vibration is less i...
Article
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Objective: Most studies suggest occlusion is not a causative factor for Trigeminal Neuralgia (TN) episodes, favoring that Trigeminal Neuralgia is caused by microvascular nerve compression. This study's objective was to determine if Trigeminal Neuralgia frequency and intensity changed after patients underwent occlusal changes to their Disclusion Tim...
Article
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Clinical methods for the diagnosis of temporomandibular joint (TMJ) internal derangements have been shown to be inadequate to consistently arrive at an accurate description of a joint's condition. Sophisticated imaging using MRI and CBCT are the most often used alternatives but have high per use costs associated with them. To avoid the unprofitable...
Article
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Statement of Problem. Most studies that tested T-Scan sensor force reproduction and repeatability have not used T-Scan clinical output data as the measure of system reproducibility. Purpose: To test the force reproduction and repeatability of the T-Scan HD sensor with a clinical output data set that is used to diagnose and adjust the occlusion. Mat...
Article
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Objective: To improve the readers' understanding and critical thinking when reading the dental literature on Vicious Cycle Theory (VCT) and the Pain Adaptation Model (PAM). Methods: Primary journal articles and systematic reviews from the dental literature about VCT and PAM were analyzed and reviewed. A Medline search of Pain Adaptation Model and T...
Article
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Objective: Evaluation of TMJ vibrations and range of motion (ROM) in subjects with muscular symptoms of temporomandibular disorders (TMDs) prior to and post Disclusion Time Reduction (DTR) therapy. The null hypothesis stated no change in TMJ vibrations and ROM. Methods and materials: The ROM and TM joint vibrations of 60 (44 F) subjects diagnosed a...
Article
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Introduction: Most theories about the etiology of Cold Sensitive Teeth suggest occlusion is not a causative factor, instead theorizing that cold sensitivity is a hydrodynamic phenomenon within open dentin tubules. Objective: This study’s objective was to determine if cold sensitivity changed after patients underwent Disclusion Time Reduction (DTR)...
Article
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Citation: Thumati, P.; Thumati, R.P.; Poovani, S.; Sattur, A.P.; Srinivas, S.; Kerstein, R.B.; Radke, J. A Multi-Center Disclusion Time Reduction (DTR) Randomized Controlled Occlusal Adjustment Study Using Occlusal Force and Timing Sensors Synchronized with Muscle Physiology Sensors. Sensors 2021, 21, 7804. https://doi.org/10.3390/ s21237804 Academ...
Article
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Objectives: The objectives of this research were; 1) to compare the changes in PHQ-15 scores to the changes in the EMG and EGN chewing data 2) to compare the progression of pain intensity, frequency of symptoms and functional restriction scores to the progression of EMG and EGN measurements. Methods: 6 TMD treatment centers recruited 82 TMD patient...
Article
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Objectives: The objectives of this research were; 1) to compare the Changes in PHQ-15 scores to the changes in the recorded Joint Vibration Analysis (JVA) data and 2) to compare the progression of pain intensity, frequency of symptoms and functional restriction scores to the concomitant progression of JVA data. Methods: Six TMD treatment centers re...
Article
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Objective: To objectively document improvements in masticatory function after full mouth reconstruction using routinely measurable variables (EMG and Jaw Motion). Methods: A series of 38 patients seeking full mouth reconstructions with severely damaged dentitions were recorded using a magnetic incisor-point tracker and a surface electromyograph. Mo...
Article
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Objective: Because no previously published migraine headache occlusal adjustment study was found, our objective was to use Disclusion Time Reduction (DTR) as a treatment for medically diagnosed migraine headache patients, to document the effects that measured occlusal adjustments have on migraine headache. Method and Materials: 120 headache and mig...
Article
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Objective: Comparing the speech motions of subjects with TMJ internal derangements to normal control subjects. Methods: The incisor-point motions of thirty subjects (19 F) with magnetic resonance imaging (MRI) verified TMJ internal derangements (ID) were recorded while reading "My Grandfather," a paragraph that contains all 44 of the phonemes of th...
Article
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Objective: The protocol included the Patient Health Questionnaire-15 (PHQ-15) to assess the apparent levels of Somatic Symptom Disorders (SSD) prior to and post successful physical treatment of TMD/orofacial pain without any psychosocial or behavioral therapy. Methods: 6 TMD treatment centers recruited TMD patients willing to answer PHQ-15 questi...
Article
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This study explains the biometric characteristics of all the three classes of Angle's Malocclusion and how important it is to examine the patient's temporomandibular joint , muscle and teeth before going for any complex restorative procedure in order to prevent any relapses or failures later . https://www.researchgate.net/publication/350159018_2154...
Article
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The article provides functional occlusion characteristics obtained with T-scan digital occlusal analysis in pre-orthodontic patients. Class I, II, and III malocclusion data are described with respect to functional occlusion.
Article
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The advent of Magnetic Resonance Imaging (MRI) and Cone Beam Computed Tomography (CBCT) have made the evaluation of the temporomandibular joint (TMJ) far more definitive than the previous X-ray technologies. However, there is a large gap between what can be accomplished diagnostically in a clinical practice setting compared to utilizing these sophi...
Article
Full-text available
Objective: Treating and managing Trigeminal Neuralgia (TN) remains a significant challenge. TN is thought to be either idiopathic in nature or related to vascular nerve compression. The purpose of this study was to treat patients diagnosed with TN utilizing the T-Scan to guide measured occlusal corrections in bite force and timing. The null hypothe...
Article
Full-text available
Introduction: Edentulous patients with conventional complete dentures (CD) are generally satisfied, but up to 30% of the patients have complaints. They suffer from a variety of problems with their dentures, especially with regard to the lower denture, such as insufficient stability, retention and pain during mastication. The quality of life in all...
Article
Full-text available
Introduction: Edentulous patients with conventional complete dentures (CD) are generally satisfied, but up to 30% of the patients have complaints. They suffer from a variety of problems with their dentures, especially with regard to the lower denture, such as insufficient stability, retention, and pain during mastication. The quality of life in all...
Article
Full-text available
Objectives: Calculate the average timing and the variability of the peak sEMG muscle activity from the bilateral masseter and anterior temporalis muscles during mastication. Compare the timings of a dysfunctional group to an asymptomatic control group. Methods: Previously recorded gum-chewing data of magnetic incisor-point tracking and simultaneou...
Article
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Objectives: Calculate the average timing and the variability of the peak sEMG muscle activity from the bilateral masseter and anterior temporalis muscles during mastication. Compare the timings of a dysfunctional group to an asymptomatic control group. Methods: Previously recorded gum-chewing data of magnetic incisor-point tracking and simultaneou...
Article
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Objective: Evaluate Radiographs from OPG, CBCT and MRI for Temporomandibular Joint Disorders (TMJD) and test for correlations with the signs and symptoms. Methods: 31 patients (62 TMJs) were included with TMJ complaints. OPG, CBCT and MRI of both the TMJ’s of each patient were taken. Associations between signs and symptoms of TMJD and the radiologi...
Article
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Objective: Retrospectively evaluate four parameters of recorded vibrations from 114 dysfunctional TMJs (69 F) divided into 4 categories when compared to 86 (48 F) age and gender matched asymptomatic control subjects’ TMJs. Methods: The TMJ vibration records of TMD patients previously diagnosed with; a.) permanently non-reducing disk displacement...
Article
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A highly biased systematic review, offered cumbrous conclusions based upon the fallacious assumption that etiology cannot be ascribed to any occlusion factor that does not have a strong association with the entire category of temporomandibular disorders. Inasmuch as association does not equal causation, the entire premise of the review is false to...
Poster
Full-text available
Objective Retrospectively evaluate four parameters of recorded vibrations from 114 dysfunctional TMJs (69 F) divided into 4 categories when compared to 86 (48 F) age and gender matched asymptomatic control TMJs. Methods The TMJ vibration records of TMD patients previously diagnosed with; 1) permanently non-reducing disk displacement DD [29], 2) dis...
Article
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Objective: The Aim of this study was to perform a computer-guided occlusal adjustment study using a Randomized Clinical Trial (RCT) design and to either corroborate or contradict the TMD symptom resolution efficacy reported in prior, non-RCT studies. Methods and Materials: 104 first year dental students were randomly assigned to a Treatment g...
Article
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Objective: Measure the median incidence and mean duration of Silent Periods (SP) in a TMD patient group and a matched control group during mastication of a tough, reproducible bolus. Methods: 20 TMD patients (11 F), with stable TMJs according to JVA and MRI, masticated a tough bolus of consistent size and texture. EMG activity was recorded from th...
Article
Full-text available
There is nothing inherently wrong with evaluating the emotional status of a temporomandibular disorders (TMD) patient. Offering sympathy for a patient’s struggles, previously known as “Bedside Manner,” may even contribute to a patient’s ultimate recovery. The strong correlation between chronic pain and emotional disturbance is very well established...
Article
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Objectives: Subjective Interpretation of articulating paper markings is still being taught as being safe for patients, despite that studies show dentists choose incorrect forceful and non-forceful contacts when using its principles. The Specific Aims of this study were to replicate or contradict prior Subjective Interpretation study findings, by us...
Article
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Costantinides, F. et al recently published a Systematic Review1 of just 3 of the 144 jaw tracking publications they found. They then concluded that: “The scientific evidence does not support the usefulness in clinical practice of Jaw Tracking devices to diagnose TMD because their diagnostic reliability is poor.” This conclusion was arrived at after...
Article
Full-text available
Drs. Dias, Rodrigues, Messias, Guerra, and Manfredini, are to be noted for their efforts in attempting to correlate Articulating Paper Markings, Optical Scanning, and T-Scan force data to each other. The authors reported a weak correlation existed between articulating paper mark area, optical scanning and T-Scan force output. The findings of a weak...
Experiment Findings
Abstract Objective: This study tested the efficacy of detecting masticatory dysfunction prior to prosthodontic treatment using incisor-point tracking and surface EMG. Additionally, the prospect of objectively detecting improvements in masticatory function post treatment was evaluated using the same measurements. Methods and materials: 30 subject...
Article
Full-text available
Objective: This study tested the efficacy of detecting masticatory dysfunction prior to prosthodontic treatment using incisor-point tracking and surface EMG. Additionally, the prospect of objectively detecting improvements in masticatory function post treatment was evaluated using the same measurements. Methods and materials: 30 subjects seeking...
Article
Full-text available
Although there are certainly more than just twelve myths regarding the diagnosis and treatment of Temporomandibular Disorders (TMD), these are some of the most confounding. Those who embrace these myths usually have just one or two favorites, but only the Deontologists among us, those who believe in following the rules regardless of the outcome, ca...
Article
Full-text available
Biometric instruments are routinely used to supply objective data that assists in the diagnosis of temporomandibular disorders (TMD). This analysis includes an organized approach to their usage. Objectives: This study sought to compare the condylar spacings of TMD patients to the normative data of Ikeda and Kawamura. A second objective was to com...
Article
Full-text available
Abstract Biometric instruments are routinely used to supply objective data that assists in the diagnosis of temporomandibular disorders (TMD). This analysis includes an organized approach to their usage. Objectives: This study sought to compare the condylar spacings of TMD patients to the normative data of Ikeda and Kawamura. A second objective w...
Chapter
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Adding modern technology to clinical diagnostic methods instead of replacing them, represents an improvement in patient care, because objective bio-physiologic measurements enhance the information obtained from the patient report of symptoms and the clinical observations made during a patient examination. Combining multiple tests has universally be...
Article
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Problem: Although Cervical Dentin Hypersensitivity (CDH) has historically been treated by the subjective use of dentin tubule medicament occluding agents, de-sensitizing agents, and other protocols, etiologic factors should be determined before treatment onset. Both cold and air stimulations for CDH have been proposed to arise from occlusal imbalan...
Article
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Objective: To test the effects of a computer-aided occlusal adjustment procedure, Immediate Complete Anterior Guidance Development (ICAGD) coronoplasty, on the smoothness, timing and velocity of gum chewing within a group of patients diagnosed with occluso-muscle dysfunction (OMD). Methods: The pre and post treatment gum-chewing jaw motion record...
Article
Full-text available
Objective: The objective was to test the efficacy of Immediate complete anterior guidance development (ICAGD) treatment applied to a select group of post orthodontic temporomandibular disorder (TMD) patients with specified myalgic symptoms. Materials and Methods: The symptoms of a carefully selected group of fifty post orthodontic myalgic TMD pati...
Article
Full-text available
Temporomandibular Disorders (TMD), always plural, constitute a category of many different mostly physical conditions. The key to successful treatment is the development of a definitive diagnosis, which allows the selection of the most appropriate treatment. TMD treatments should be aimed at all of the underlying causative factors, not limited to ma...
Article
Objective: The objective was to test the efficacy of immediate complete anterior guidance development (ICAGD) treatment applied to a select group of postorthodontic temporo‑mandibular disorder (TMD) patients with specified myalgic symptoms. Materials and Methods: The symptoms of a carefully selected group of fifty postorthodontic myalgic TMD patien...
Article
Objective: To compare the results obtained in instrumental analysis of temporomandibular joints function using joint vibration analysis and computerized axiography in healthy young adults. Methods: The study involved 187 people aged 18–21 years old. All the participants were subjected to a clinical examination and instrumental diagnostics that incl...
Article
Open Journal of Advanced Dental Technologies & Techniques 30 October 2018, Vol.1 No.1 Al-Sulaihi et al MASTICATORY ANALYSIS OF AN EDENTULOUS PATIENT, CASE REPORT Dr. Khulood Al-Sulaihi, Prof. Prafulla Thumati, Prof. Shwetha Poovani, John Radke Abstract: Objective: To evaluate any improvements in masticatory function as a patient progresses from...
Article
Full-text available
Abstract Objective: To evaluate the TMJ vibrations and Range of Motion (ROM) changes in Occluso-muscle disorder (OMD) subjects before and after undergoing the ICAGD coronoplasty. The null hypothesis = no change. Materials and Methods: Opening and closing Range of Motion (ROM) and TM joint vibrations were recorded from 43 muscularly symptomatic subj...
Article
Full-text available
This article describes the advantages of applying technology to the process of diagnosis. It focuses on the diagnosis of functional maladies of the masticatory system rather than conditions like caries or the more commonly diagnosed routine dental conditions. The discussion includes the recording and analysis of EMG activity, mandibular kinesiology...
Article
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ABSTRACT Introduction: There is limited literature describing the use of psychological testing on TMD patients who undergo occlusal treatment. Objective: The aim of this study of carefully selected muscular TMD subjects, was whether Beck Depression Inventory-II (BDI-II) scores could be reduced by the measured occlusal treatment, Immediate Complete...
Article
Full-text available
Objective: To evaluate the TMJ vibrations and Range of Motion (ROM) changes in Occluso-muscle disorder (OMD) subjects before and after undergoing the ICAGD coronoplasty. The null hypothesis = no change. Materials and Methods: Opening and closing Range of Motion (ROM) and TM joint vibrations were recorded from 43 muscularly symptomatic subjects wit...
Article
Full-text available
Objective of the study was to evaluate the clinical status of the masticatory system in young adults with full permanent dentition and no stomatognathic system complaints. The study involved 186 randomly selected people with full dental arches with normal occlusal conditions corresponding to Angle’s Class I aged 18 - 21 years with an average age of...
Article
Objective: The null hypothesis was that mandibular amplitude, velocity, and variability during gum chewing are not altered in subjects with temporomandibular joint (TMJ) internal derangements (ID). Methods: Thirty symptomatic subjects with confirmed ID consented to chew gum on their left and right sides while being tracked by an incisor-point jaw t...
Chapter
Adding technology to clinical diagnosis improves patient care, because objective measurements enhance the patient's report of symptoms and the observations made during an examination. The combination of multiple tests has universally been acknowledged to improve diagnostic sensitivity and specificity, as well as add value to treatment effectiveness...
Article
Full-text available
The process of mastication is an essential function for the survival of dentate organisms and has long been a subject of the study in the dental literature. PubMed lists 11,202 references to articles on mastication from 1914 to the present. Moreover, dentistry pays too little attention to a patient’s ability to chew food. The teeth that we fill, ex...
Article
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Objective: To verify the efficacy of treating dentin/dental hypersensitivity (DH) to Cold Ice Water Swish testing before and after subjects undergo the Immediate Complete Anterior Guidance Development (ICAGD) computer-guided occlusal adjustment. Methods: One hundred chronically dysfunctional patients with known cold sensitivity swished ice water in...
Article
Full-text available
Objectives: Studies involving electrognathographic (EGN) recordings of chewing improvements obtained following occlusal adjustment therapy are rare, as most studies lack 'chewing' within the research. The objectives of this study were to determine if reducing long Disclusion Time to short Disclusion Time with the immediate complete anterior guidan...
Article
Full-text available
The objective of the present study was to precisely characterize the temporomandibular joint (TMJ) vibrations of a youthful, adult and completely asymptomatic population, looking for differences between genders and with respect to age. Two hundred thirty-seven asymptomatic subjects (163 females, 74 males) from the Dayananda Sagar Institute in India...
Conference Paper
Full-text available
Objective: To test the null hypothesis that the mandibular movements during gum chewing do not differ significantly in the presence of a verified TMJ internal derangement. Methods: 30 symptomatic subjects with confirmed internal derangement of at least one TMJ (15 f, 15 m, 38.9 + 15.8 years old) consented to chew gum on their left and right sides...
Conference Paper
Full-text available
Objective: An internal derangement (ID) of the TMJ may affect the process of mastication. This research tested the null hypothesis: No difference in the Jerk function during mastication between ID patients and control subjects. Methods: Incisor-point motions were recorded from patients (56 F & 56 M) with documented ID of at least one TMJ while che...
Article
Full-text available
Objective: To compare 10 Hz wide segments of the 0 to 1000 Hz frequency distributions of vibrations recorded from five stages of internally deranged and asymptomatic temporomandibular joints (TMJs). Methods: TMJ vibrations were recorded from 236 patients with five stages of TMJ dysfunction: (1) reducing partial disc displacement (PDDR, n=39); (2...
Article
Full-text available
Aims: The objectives were to find specific factors that are mathematically distinct between the chewing timings, movement pattern shapes, variability, and movement velocities of: (1) normal asymptomatic subjects and (2) a group of subjects with verified temporomandibular joint (TMJ) internal derangements. Methodology: Left- and right-sided chewi...
Article
Full-text available
The aim of this study was to determine whether Subjective Interpretation of paper markings is a reliable method for identifying the relative occlusal force content of tooth contacts. 295 clinicians selected the "Most Forceful" and "Least Forceful" occlusal contacts in six occlusal-view photographs of articulating paper marks that were later compare...
Chapter
Full-text available
Adding technology to clinical diagnosis improves patient care, because objective measurements enhance the patient's report of symptoms and the observations made during an examination. The combination of multiple tests has universally been acknowledged to improve diagnostic sensitivity and specificity, as well as add value to treatment effectiveness...
Article
Full-text available
The null hypothesis was that pain pressure thresholds are the same for young healthy males and females and do not differ between the temporomandibular joint (TMJ) and muscle sites. The aim of the current study was to compare pain pressure threshold levels using an algometer with a convex-formed contact piece and pressure increase rates similar to t...