Johannes Jungilligens

Johannes Jungilligens
Universitätsklinikum Knappschaftskrankenhaus Bochum | UK RUB · Department of Neurology

Ph.D. (Dr. rer. nat.)

About

25
Publications
3,284
Reads
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145
Citations
Introduction
Clinical neuropsychologist and Ph.D. in psychology and neuroscience, working on the neural signature of affective and metacognitive processes in patients with functional/dissociative seizures. Skilled in the acquisition and analysis of structural neuroimaging data, behavioural, and psychometric data, as well as trained in working with neurological and psychiatric patients in clinical and research settings.
Additional affiliations
February 2021 - July 2021
Massachusetts General Hospital
Position
  • Visiting Post-Doctoral Researcher
February 2021 - July 2021
Harvard Medical School
Position
  • Visiting Post-Doctoral Researcher
November 2016 - present
Universitätsklinikum Knappschaftskrankenhaus Bochum
Position
  • Research Assistant
Education
November 2016 - September 2020
Ruhr-Universität Bochum
Field of study
  • Neuropsychology and Cognitive Neuroscience
October 2014 - September 2016
Ruhr-Universität Bochum
Field of study
  • Psychology and Cognitive Neuroscience
October 2011 - September 2014
Ruhr-Universität Bochum
Field of study
  • Psychology

Publications

Publications (25)
Article
Functional neurological disorder (FND) reflects impairments in brain networks leading to distressing motor, sensory, and/or cognitive symptoms that demonstrate positive clinical signs on examination incongruent with other conditions. A central issue in historical and contemporary formulations of FND has been the mechanistic and etiological role of...
Article
Background: Dissociative seizures (DS) are a common subtype of functional neurological disorder (FND) with an incompletely understood pathophysiology. Here, gray matter variations and their relationship to clinical features were investigated. Methods: Forty-eight patients with DS without neurological comorbidities and 43 matched clinical control...
Preprint
Objective: Adverse life experiences (ALEs) increase the susceptibility to functional (somatoform/dissociative) symptoms, likely through neurodevelopmental effects. This analysis aimed to illuminate potential genetic influences in neuroanatomical variation related to functional symptoms and ALEs in patients with functional seizures. Methods: Questio...
Article
Full-text available
Objective To determine the epidemiology of prolonged psychogenic non-epileptic seizures (pPNES) misdiagnosed as status epilepticus, as well as the risks associated with non-indicated treatment. Methods We performed an individual patient data analysis from the Rapid Anticonvulsant Medication Prior to Arrival Trial (RAMPART) and the Established Stat...
Article
Full-text available
Functional neurological (conversion) disorder (FND) was of great interest to early clinical neuroscience leaders. During the 20th century, neurology and psychiatry grew apart - leaving FND a borderland condition. Fortunately, a renaissance has occurred in the last two decades, fostered by increased recognition that FND is prevalent and diagnosed us...
Article
Full-text available
Visual and cognitive skills are key to successful functioning in highly demanding settings such as elite sports. However, their mutual influence and interdependencies are not sufficiently understood yet. This cross-sectional study examined in a cross-sectional study design the relationship of between visual skills and executive functions in elite s...
Article
Full-text available
Within stress-diathesis models, adverse life experiences (ALEs) increase the susceptibility to functional neurological symptoms through neuroplasticity effects. We aimed to characterize potential genetic influences on this relationship in 20 patients with functional seizures. Questionnaires, structural MRIs and Allen Human Brain Atlas gene expressi...
Poster
Full-text available
Objective: This study aimed to illuminate potential gene expression influences in neuroanatomical variation related to adverse life experiences (ALEs) and functional neurological symptom severity in patients with functional seizures. Background: ALEs increase the susceptibility to psychopathologies, likely through neurodevelopmental and genetic eff...
Presentation
Full-text available
Overview of structural neuroimaging findings in functional neurological disorder + a discussion of challenges and opportunities for the field.
Article
Full-text available
Neurocognitive screening instruments usually require printed sheets and additional accessories, and can be unsuitable for low-threshold use during ward rounds or emergency workup, especially in patients with motor impairments. Here, we test the utility of a newly developed neuropsychology pocketcard set for point-of-care testing. For aphasia and ne...
Article
Full-text available
Background: Consensus criteria for autoimmune limbic encephalitis (ALE) allow for a diagnosis even without neural antibodies (Abs), but it remains unclear which clinical features should prompt neural Ab screening in temporal lobe epilepsy patients. Methods: We identified 47 patients from a tertiary epilepsy center with mediotemporal lobe seizure...
Article
Purpose: To identify variations in white matter tract integrity related to behavioural control in response to emotional stimuli in patients with dissociative seizures (DS) and healthy controls (HC), and examine associations with illness characteristics and psychological trauma history. Methods: Twenty DS patients and 20 HC completed an emotional...
Thesis
Full-text available
Dissociative seizures are brief episodes of altered awareness and behavioural control which are assumed to be of psychological origin. In this dissertation, emotion processing and metacognitive functions in patients with dissociative seizures are investigated using an experimental-behavioural approach, self-report questionnaires, and high-quality d...
Article
Full-text available
Objective To determine the utility of suggestive seizure induction for inpatient work‐up of suspected psychogenic nonepileptic seizures (PNES). Methods Prospective study of epilepsy center inpatient admissions with suspected PNES. Patients were randomized to undergo suggestive induction first (group A) and then, if necessary, long‐term video–elect...
Article
Full-text available
Background: Dissociative seizures (DS) are brief episodes of disrupted awareness and behavioural control that may resemble epileptic seizures. They are thought to arise in the context of impaired emotion processing and disinhibition. In a multi-perspective neuropsychological study, we aim to assess specific metacognitive traits and behavioural fea...
Poster
Full-text available
Background: Dissociative seizures (DS) are thought to arise in the context of impaired emotion processing and disinhibition. Still, despite a wealth of theoretical considerations and pathophysiological models, experimental behavioural evidence of these critical affective and cognitive underpinnings of dissociative seizures is still scarce. In a mul...
Article
Increasing evidence from neuroimaging studies points towards a hippocampal role in resolving approach‐avoidance goal conflicts. Furthermore, previous neuroimaging findings suggest that the hippocampus (HC) contributes to successful conflict resolution as it is measured, for example, in a Stroop paradigm. However, it is still an open question whethe...
Poster
Full-text available
Dissoziative Anfälle sind in ihrer Ätiologie noch nicht vollständig verstanden. Als Schlüsselpunkte in der Krankheitsentstehung werden in aktuellen Modellen unter anderem Veränderungen in Emotionserkennen und Emotionsverarbeitung hervorgehoben; insbesondere sind hohe Alexithymie-Werte bei Patienten mit dissoziativen Anfällen typisch. Alexithymie be...
Article
Dissociative seizures are a common and often elusive differential diagnosis in epilepsy centers. Considering their high prevalence, long diagnostic delays, and disappointing rates of treatment response, scientific research dedicated to dissociative seizures is surprisingly scarce. In order to chart the scientific landscape of dissociative seizures...
Article
Psychogenic nonepileptic seizures (PNES) can remain undiagnosed for many years, leading to unnecessary medication and delayed treatment. A recent report by the International League Against Epilepsy Nonepileptic Seizures Task Force recommends a staged approach to the diagnosis of PNES (LaFrance, et al., 2013). We aimed to investigate its practical u...
Poster
Full-text available
Einleitung: Psychogene nicht-epileptische Anfälle (PNES) weisen symptomatische Ähnlichkeit zu epileptischen Anfällen auf, ohne die definierende pathologische neuronale Aktivität als Grundlage zu haben. Ihre Pathogenese basiert primär auf psychologischen Prozessen; unter anderem auf einer abnormen Verarbeitung von Stress. Zunehmend rückt bei der äti...
Article
The interplay of perception and memory is very evident when we perceive and then recognize familiar stimuli. Conversely, information in long-term memory may also influence how a stimulus is perceived. Prior work on number cognition in the visual modality has shown that in Western number systems long-term memory for the magnitude of smaller numbers...

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