Johanna Simin

Johanna Simin
Karolinska Institutet | KI

Doctor of Medicine
A passionate postdoctoral researcher and driven entrepreneur

About

11
Publications
487
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108
Citations
Introduction
Postdoctoral researcher at the Centre for Translational Microbiome Research (CTMR), focusing on the role of the human microbiome in our longer-term health, particularly within gastrointestinal, women's health and cancer projects. A strong focus is on biostatistics, state-of-art microbiome techniques and combining microbiome data with large registries. Supervision: Presently supervising 3 master students, of which 1 as a co-supervisor (Karolinska Institutet) and 2 as external supervisor.
Additional affiliations
December 2021 - present
Karolinska Institutet
Position
  • PostDoc Position
October 2021 - November 2021
University of Antwerp
Position
  • Lecturer
August 2021 - June 2022
University of Antwerp
Position
  • Master's Student
Education
December 2016 - June 2021
Karolinska Institutet
Field of study
  • Clinical Epidemiology
August 2014 - June 2016
Karolinska Institutet
Field of study
  • Epidemiology
January 2004 - June 2009

Publications

Publications (11)
Article
Full-text available
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that affects women in reproductive age and represents an unfavourable risk factor for several pregnancy and perinatal outcomes. Despite, no guidelines or pharmaceutical strategies for treating PCOS during pregnancy are available. The aim of this study is to determine the associa...
Article
Full-text available
Background: The net effect of menopausal hormone therapy on the risk of death is understudied, and current evidence is conflicting. Our aim was to investigate the association between menopausal hormones and risk of all-cause, cardiovascular, and cancer-specific mortality, based on the Swedish Prescribed Drug Registry and National Patient Registry....
Article
Full-text available
Hepatitis D virus (HDV) infection causes a severe chronic viral hepatitis with accelerated development of liver cirrhosis and decompensation, but whether it further increases the risk of hepatocellular carcinoma (HCC) is unclear. We performed a comprehensive systematic review of the published literature and meta‐analysis to assess the risk of HCC i...
Article
Full-text available
Background: Menopausal hormone therapy (MHT) has been associated with various malignancies. Aims: To investigate the association of various MHT regimens with the risk of colorectal cancer (CRC). Methods: All MHT ever-users (n = 290 186) were included through the Swedish Prescribed Drug Registry, with a 1:3 group-level matching to non-users. Ev...
Article
Full-text available
Background Menopausal hormone therapy (MHT) reduces the risk of developing colorectal cancer (CRC), yet it is largely unclear whether it could also influence survival in women with CRC. Therefore, we aimed to investigate the influence of prediagnostic MHT use on CRC-specific and all-cause mortality in women with CRC. Methods This nationwide nested...
Article
Full-text available
Background: It is understudied whether the posed association of oral antibiotics with colorectal cancer (CRC) varies between antibiotic spectrums, colorectal continuum, and if a non-linear dose-dependent relationship is present. Design: Three electronic databases and a trial platform were searched for all relevant studies, from inception until F...
Article
Objective Oral antibiotics are posed as a possible risk factor for breast cancer. Evidence is insufficient to determine whether the choice of antibiotic class could effect this potential association, and non-linearity has not been studied. We aimed to fill these important knowledge gaps. Methods PubMed, Web of Science, Embase and a trial registry...
Article
Although menopausal hormone therapy (MHT) seemingly increases the risk of ovarian cancer, evidence is insufficient whether the risk varies between various MHT formulations, regimens and administration modes. With the aim of filling these knowledge gaps, we investigated the effect of different MHT treatment options on the risk of ovarian cancer. Thi...
Article
Aim: We aimed to assess the overall cancer risk among contemporary menopausal hormone therapy (MHT) users in Sweden and the risk for different cancer types. Methods: A nationwide Swedish population-based cohort study including all 290,186 women aged ≥ 40 years having used systemic MHT during the study period (July 2005 and December 2012), compar...

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Project (1)