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Introduction
Current institution
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April 2011 - present
Publications
Publications (129)
Background
The prevalence of respiratory dysfunction in PD is unknown and a better understanding of determinants contributing to respiratory dysfunction is important to facilitate early recognition and treatment.
Objective
To examine the prevalence and determinants of self-reported symptoms of respiratory dysfunction among people with PD.
Methods...
Background
Persons with COVID‐19 may experience limitations in daily functioning and can be referred to occupational therapy.
Objectives
To evaluate changes in daily functioning, cognitive complaints, fatigue and self-management of persons with COVID-19 who received occupational therapy in primary care.
To get insights in the volume and duration o...
Background
Increasing evidence supports the merits of speech therapy in Parkinson's disease, but the current practice of multiple in-house treatments is demanding for patients. We therefore assessed the effectiveness of remotely delivered and personalised speech therapy on improving quality of life and speech quality in persons with Parkinson's dis...
People with Parkinson’s disease (PD) experience a range of progressive motor and non-motor symptoms, that negatively affect their daily functioning, social participation and quality of life. Allied health therapies have emerged as an effective treatment approach—complementary to pharmacological and neurosurgical treatments—which reduces the impact...
Dysarthria is disabling in persons with degenerative ataxia. There is limited evidence for speech therapy interventions. In this pilot study, we used the Voice trainer app, which was originally developed for patients with Parkinson’s disease, as a feedback tool for vocal control. We hypothesized that patients with ataxic dysarthria would benefit fr...
Background and Objectives
Oculopharyngeal muscular dystrophy (OPMD) is a rare progressive neuromuscular disease. MRI is one of the techniques that is used in neuromuscular disorders to evaluate muscle alterations. The aim of this study was to describe the pattern of fatty infiltration of orofacial and leg muscles using quantitative muscle MRI in a...
Background
Persons with dementia are at risk of developing nutritional problems. Theoretical models on nutritional problems have been developed, but have not been evaluated with healthcare professionals.
Objective
This study aimed to explore the comprehensiveness and applicability of a theoretical model of nutritional problems in persons with deme...
Background
Dysarthria is disabling in persons with degenerative ataxia. There is limited evidence for speech therapy interventions. In this pilot study, we used the Voice trainer app, which was originally developed for patients with Parkinson’s disease, as a feedback tool for vocal control. We hypothesized that patients with ataxic dysarthria would...
Background:
Females, people with young-onset PD and older individuals, and non-white populations are historically underrepresented in clinical Parkinson's disease (PD) research. Furthermore, research traditionally focused predominantly on motor symptoms of PD. Including a representative and diverse group of people with PD and also studying non-mot...
Background:
Communication difficulties are common in people with dementia, and often present from an early stage. However, direct treatment options for people with dementia that positively influence their daily communication are scarce.
Aims:
To evaluate the potential impact and feasibility of a personalized logopaedic intervention.
Methods & p...
Background
Patients recovering from COVID-19 often experience persistent problems in their daily activities related to limitations in physical, nutritional, cognitive, and mental functioning. To date, it is unknown what treatment is needed to support patients in their recovery from COVID-19.
Objective
This study aimed to evaluate the primary allie...
BACKGROUND
Patients recovering from COVID-19 often experience persistent problems in their daily activities related to limitations in physical, nutritional, cognitive, and mental functioning. To date, it is unknown what treatment is needed to support patients in their recovery from COVID-19.
OBJECTIVE
This study aimed to evaluate the primary allie...
Background and Objective: This study explored the feasibility and usefulness of a set of observer rated outcome measures for the joint verbal functional communication of people with dementia and their communication partners, in combination with a set of quantitative measures for the language ability of the person with dementia. We hypothesized that...
Objectives: To report the recovery of patients receiving primary allied healthcare after a COVID-19 infection at a six-month follow-up, and to explore which patient characteristics are associated with the changes in outcomes between the baseline and six-month follow-up.
Design: Prospective cohort study.
Setting: Allied healthcare in Dutch primary c...
Background:
Several conditions and diseases can result in speech problems that can have a negative impact on everyday functioning, referred to as communicative participation. Subjective problems with acquired speech problems are often assessed with the speech handicap index (SHI). To assess generic participation problems, the Utrecht Scale for Eva...
Introduction/aims:
Oculopharyngeal muscular dystrophy (OPMD) is a late onset, progressive muscle disease. Muscle ultrasound (QMUS) assesses structural changes in muscles and is a sensitive biomarker in neuromuscular disorders. The aim of this study was to assess whether QMUS can detect muscle pathology and can be used as longitudinal imaging bioma...
Objective:
To report the study protocol and baseline characteristics of a prospective cohort study to evaluate longitudinal recovery trajectories of patients recovering from COVID-19 who have visited a primary care allied health professional.
Design:
Prospective cohort study with a mixed-methods approach.
Patients:
Patients recovering from COV...
Background
Abnormal respiratory function tests can be observed early in the course of Parkinson’s disease (PD). A better understanding of the impact of respiratory dysfunction on daily life in PD is needed to prevent later occurring complications as a (aspiration) pneumonia.
Objective
To explain which respiratory symptoms people with PD or a form...
Objective
The purpose of this study was to explore lived experiences of rehabilitation professionals working in hospitals during the COVID-19 pandemic, including the ethical issues and moral distress that these professionals might have encountered.
Methods
An interpretative phenomenological study was performed. First-person experiences of rehabili...
Objective
To evaluate the effectiveness of personalized and home-based speech therapy on quality of life, intelligibility, and social participation for people with Parkinson’s disease (PD) who have a reduced intelligibility of speech.
Background
Speech problems in PD have a profound negative impact on social interaction and quality of life. Eviden...
COVID-19 has had an impact globally with millions infected, high mortality, significant economic ramifications, travel restrictions, national lockdowns, overloaded healthcare systems, effects on healthcare workers’ health and well-being, and large amounts of funding diverted into rapid vaccine development and implementation. Patients with COVID-19,...
Background and Objectives
Tools to measure self-perceived communication between persons with early-stage dementia and their caregivers are lacking. Therefore, we developed a questionnaire for Experienced Communication in Dementia (ECD) with a patient version (ECD-P) and a caregiver version (ECD-C), that contains items on (1) caregiver competence, (...
Purpose:
The Radboud Dysarthria Assessment (RDA) was published in 2014. Adaptation into a pediatric version (p-RDA) was required because of relevant differences between children and adults. The purpose of this study was to assess the feasibility of the p-RDA and to test intra-rater and inter-rater reliability as well as the validity of the two sev...
Objective
Oculopharyngeal muscular dystrophy (OPMD) is a late-onset, progressive muscle disease. Disease progression is known to be slow, but details on the natural history remain unknown. We aimed to examine the natural history of OPMD in a large nationwide cohort to determine clinical outcome measures that capture disease progression and can be u...
Communication problems with their caregivers are common in people with dementia. Although interventions for improvement of communication are being developed, a tool to measure how participants experience their communication is lacking. The objective of this article is to describe the development of a questionnaire that measures the “experienced com...
Background
The outbreak of COVID-19 led to a large number of hospitalizations in the Netherlands and worldwide. As a result, the work of hospital-based allied health professionals changed rapidly. In such a healthcare crisis, professionals may not be able to fulfill their own professional values about good care, resulting in ethical issues and mora...
Objective
To identify core practices for workforce management of communication and swallowing functions in COVID-19 positive patients within the ICU.
Design
A modified Delphi methodology was utilized, with 3 electronic voting rounds. AGREE II and an adapted COVID-19 survey framework from physiotherapy were used to develop survey statements. Sixty-...
Background
Signs of respiratory dysfunction can be present already early in the course of Parkinson’s disease (PD). Respiratory training could alleviate this, but its effectiveness is not well understood.
Objective
The purpose of this systematic review is to review the efficacy of different respiratory training interventions in PD.
Methods
A sear...
Background: Oculopharyngeal muscular dystrophy (OPMD) is a late onset progressive neuromuscular disorder. Although dysphagia is a pivotal sign in OPMD it is still not completely understood. Objective: The aim of this study was to systematically investigate oropharyngeal functioning in a large OPMD population. Methods: Forty-eight genetically confir...
Small non-coding microRNAs (miRNAs) are involved in the regulation of mRNA stability. Their features, including high stability and secretion to biofluids, make them attractive as potential biomarkers for diverse pathologies. This is the first study reporting miRNA as potential biomarkers for oculopharyngeal muscular dystrophy (OPMD), an adult-onset...
Background:
Oculopharyngeal muscular dystrophy (OPMD) is a late onset progressive neuromuscular disorder. Although dysphagia is a pivotal sign in OPMD it is still not completely understood.
Objective:
The aim of this study was to systematically investigate oropharyngeal functioning in a large OPMD population.
Methods:
Forty-eight genetically c...
Objective:
To identify the essential elements of a newly developed, practice-based logopaedic intervention, which focuses on communication between persons with dementia (PwDs) and their caregivers.
Methods:
The intervention of 6 one-hour sessions was conducted and evaluated with 4 PwD-caregiver dyads. Eighteen therapy sessions were video recorde...
Objective:
To translate and linguistically and culturally adapt to Brazilian Portuguese, and verify the reliability and validity of the Radboud Oral Motor Inventory for Parkinson's Disease (ROMP).
Methods:
The ROMP was translated and retranslated, and the instrument reliability was verified by analyzing the internal consistency and the reproducibi...
Purpose: Maximum performance tests examine upper limits of speech motor performance, as used by speech-language pathologists in dysarthria assessment protocols. The Radboud Dysarthria Assessment includes maximum repetition rate, maximum phonation time, fundamental frequency range and maximum phonation volume to assist in detecting pathological perf...
Objective:
In the absence of an adequate dysarthria assessment in the Netherlands, we developed the Radboud Dysarthria Assessment (RDA). This article describes its development and clinimetric evaluation.
Patients and methods:
Forty-three patients were assessed with the RDA. The recording forms were subjected to exploratory factor analysis and es...
Objective: To assess the feasibility of using 24-hours ambulatory impedance-pH monitoring (24-hAlpHM) to precisely measure saliva swallowing frequency (SSF) in patients with Parkinson’s disease (PD). Background: The pathophysiology of drooling is multifactorial, including reduced swallowing capacity, open mouth due to hypomimia, and stooped posture...
Background:
Endoscopic cricopharyngeal myotomy (ECPM) using CO2 laser surgery presents a less invasive treatment technique when compared to transcervical cricopharyngeal myotomy.
Methods:
Forty-seven patients who underwent ECPM from 2002 until 2013 were included in this study. Patient characteristics, and preoperative and postoperative outcome a...
Objectives:
Botulinum neurotoxin (BoNT) injections in the salivary glands and radiotherapy (RT) on these glands are commonly used to alleviate severe drooling in patients with amyotrophic lateral sclerosis (ALS). This study compares BoNT type A with RT based on patient-rated evaluations.
Materials & methods:
A prospective randomized controlled p...
Purpose: Reduced saliva swallowing frequency (SSF) is considered a causal factor of drooling in Parkinson's disease (PD), however not fully demonstrated and understood yet. SSF should preferably be measured during 24 h in everyday life. This study assessed the feasibility of using the 24-hours ambulatory impedance-pH monitoring (24-hAlpHM; used to...
Background: Dysphagia resulting in altered food intake is common among head and neck cancer patients. This randomized trial investigated the effect of combined individual dietary counseling (IDC) with individualized swallowing therapy (intervention) compared to IDC (control) on normalcy of food intake (NFI). Methods: Patients with stage II-IV head...
Oropharyngeal dysphagia in neurodegenerative diseases:
Neurodegenerative diseases are progressive degenerations of the brain with increasing movement disorders, like gait, speech and swallowing disorders combined with cognitive disorders, like dementia. Neurodegenerative diseases have in common that aspiration pneumonia is the most frequent cause...
Oropharyngeal swallowing disorders in parkinson's disease:
Parkinson's disease is one of the most common and best studied neurodegenerative diseases. The typical motor features, like hypokinesia and rigidity are also seen in chewing and swallowing, but this 'hypokinetic dysphagia' is a complaint that generally occurs in the later stages of the dis...
Stoornissen in het kauwen en slikken bemoeilijken het adequaat innemen van voedsel. Slikstoornissen ontstaan met name door neurologische aandoeningen (o.a. beroerte of spierziekte) of tumoren in het hoofd- en halsgebied. De diagnose wordt gesteld op basis van de klachten van de patiënt, observatie en testen van het slikken en zonodig radiologisch o...
Het NDO-V is in vijf fasen tot stand gekomen.
SamenvattingHet Nederlandstalig Dysartrieonderzoek voor volwassenen (NDO-V) is een onderzoeksinstrument, waarmee logopedisten in Nederland en Vlaanderen kunnen vaststellen of een patiënt1 een dysartrie heeft, en zo ja, wat de aard en de ernst daarvan zijn.Het NDO-V:
Dysartrie is een verzamelnaam voor een groep neurologische spraakstoornissen ten gevolge van afwijkingen in kracht, snelheid, bereik, stabiliteit, tonus of nauwkeurigheid van spieren die nodig zijn voor de realisatie van de ademhalings-, fonatie-, resonantie-, articulatie- en prosodische aspecten van de spraakproductie1.
Purpose:
Patients with a neuromuscular disease (NMD) can present with dysarthria and/or dysphagia. Literature regarding prevalence rates of dysarthria and dysphagia is scarce. The purpose of this study was to determine prevalence rates, severity and co-presence of dysarthria and dysphagia in adult patients with NMD.
Method:
Two groups of adult p...
Dysphagia and drooling are frequently reported consequences of Parkinson’s disease (PD) and this article aims to review their management. Several PD-specific and validated instruments are available for the screening and evaluation of dysphagia and drooling, including the Swallowing Disturbance Questionnaire (SDQ), Sialorrhea Clinical Scale for Park...
Stoornissen in het kauwen en slikken bemoeilijken het adequaat innemen van voedsel. Oorzaken van slikstoornissen zijn vaak neurologische ziekten of mechanische veranderingen door ingrepen in het hoofd- en halsgebied. Afhankelijk van de oorzaak en de slikfase die is aangedaan, bestaat de behandeling uit oefeningen om het kauwen en slikken efficiënte...
Dysphagia is a potentially harmful feature, also in Parkinson's disease (PD). As published prevalence rates vary widely, we aimed to estimate the prevalence of oropharyngeal dysphagia in PD in a meta-analysis. We conducted a systematic literature search in February 2011 and two independent reviewers selected the papers. We computed the estimates of...
Drooling is an incapacitating feature of Parkinson's disease. Better pathophysiological insights are needed to improve treatment. In this study, we tested the hypothesis that the cause of drooling is multifactorial. We examined 15 patients with Parkinson's disease with distinct diurnal saliva loss ("droolers") and 15 patients with Parkinson's disea...
To report on the development and psychometric evaluation of the Radboud Oral Motor Inventory for Parkinson's Disease (ROMP), a newly developed patient-rated assessment of speech, swallowing, and saliva control in patients with Parkinson's disease (PD).
Reliability and validity study.
Tertiary-care Parkinson center for multidisciplinary assessment....
Drooling as symptom of Parkinson's disease (PD) has thus far been poorly defined. This uncertainty is reflected by high variations in published prevalence rates. The aim of this study was to investigate the prevalence of saliva loss versus accumulation of saliva as a possible preliminary stage, and diurnal drooling versus nocturnal drooling. In add...
Improved diagnostic sophistication is increasingly enabling neurologists to differentiate between Parkinson's disease and other atypical parkinsonism (AP), such as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and dementia with Lewy bodies. The Handbook of Atypical Parkinsonism is a comprehensive survey of all...
De ICF, de Nederlandse vertaling van de International Classification of Functioning, Disability and Health (2001), beschrijft algemene en specifieke aspecten van communicatie via taal, tekens en symbolen, inclusief het begrijpen en produceren van boodschappen, converseren en het gebruiken van communicatieapparatuur en -technieken (d310 t/m d360).
Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder with a complex phenotype, featuring a wide variety of both motor and non-motor symptoms. Current medical management is usually monodisciplinary, with an emphasis on drug treatment, sometimes supplemented with deep brain surgery. Despite optimal medical management, most...
Drooling (saliva loss) is a frequently reported symptom in patients with Parkinson’s disease (PD), but an accurate estimate
of the prevalence of drooling is lacking. The aim of this study was to systematically review the prevalence of drooling in
published research papers. A systematic PubMed and CINAHL search was done, including studies published...
A 71-year-old man with a 13-year history of idiopathic Parkinson’s disease (PD) was referred to us because of severe and intractable drooling. His complaints started 4 years earlier with nocturnal drooling, but this had progressed to profuse drooling throughout the day. By that time he also suffered from severely impaired swallowing and severe hypo...
Kauw- en slikstoornissen zijn geen aandoeningen of ziekten op zichzelf, maar zijn het gevolg van een ziekte of beschadiging.
De oorzaken van kauwen slikstoornissen zijn grofweg in twee groepen te verdelen: neurologische oorzaken en niet-neurologische
oorzaken.(1-3)
Het vaststellen en analyseren van slikstoornissen en voedingsproblemen is het werk van verschillende disciplines. Bij de intake
van een patiënt in een ziekenhuis, verpleeghuis of polikliniek is de verpleegkundige meestal degene die het eerste met de
patiënt te maken krijgt. In dit hoofdstuk komen daarom verschillende screeningen aan bod om vast te...
Het vaststellen en analyseren van slikstoornissen en voedingsproblemen is het werk van verschillende disciplines. Bij de intake van een patiënt in een ziekenhuis, verpleeghuis of polikliniek is de verpleegkundige meestal degene die het eerste met de patiënt te maken krijgt. In dit hoofdstuk komen daarom verschillende screeningen aan bod om vast te...
Om gezond te blijven moeten patiënten met kauw- en slikstoornissen een voldoende inname van vocht en voeding kunnen bereiken
en een goede voedingstoestand kunnen handhaven. Vooral bij ernstige slikstoornissen en ADL-afhankelijkheid verdient dat veel
aandacht, ongeacht de etiologie en de setting. De oplossing in de vormvan een dieetbehandeling is af...
Om de diversiteit van stoornissen in het kauwen en slikken te kunnen begrijpen is het belangrijk de normale fysiologie van
het slikken te kennen. Volgens de klassieke indeling is het slikken verdeeld in vier fasen, een beschrijving die in 1983 bekend
werd door het eerste handboek over orofaryngeale slikstoornissen van Logemann(1) en sindsdien inter...
Dysphagia in Parkinson's disease. Parkinson's disease (PD) is characterised by a combination of progressive movement disorders and non-motor dysfunctions. Dysphagia is a common complaint, often with considerable physical and social consequences. This goal of this review is to present the epidemiology and pathophysiology of dysphagia in PD and to su...
Volgens het uitgangspunt van dit boek zijn bij de behandeling van kauw- en slikstoornissen in het algemeen meerdere disciplines betrokken. Het behandelproces en de resultaten daarvan worden bepaald door de manier waarop beroepsbeoefenaars met elkaar samenwerken. De mogelijkheden om deze samenwerking vorm te geven worden beïnvloed door een veelheid...
