Jing Zhang

Jing Zhang
The Northwest Normal University · Computer science

About

191
Publications
18,572
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3,391
Citations
Citations since 2016
63 Research Items
2410 Citations
20162017201820192020202120220100200300400500
20162017201820192020202120220100200300400500
20162017201820192020202120220100200300400500
20162017201820192020202120220100200300400500
Introduction
Skills and Expertise

Publications

Publications (191)
Article
Full-text available
Liver X receptors (LXRs) are important regulators of cholesterol metabolism and inflammatory responses. LXR agonists exhibit potently anti-inflammatory effects in macrophages, which make them beneficial to anti-atherogenic therapy. In addition to transrepressive regulation by SUMOylation, LXRs can inhibit inflammation by various mechanisms through...
Article
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For rapid discovery of novel SARS-CoV-2 main protease (Mpro) inhibitors, an optimized fluorescence resonance energy transfer (FRET)-based high-throughput screening (HTS) assay was developed. The recombinant Mpro was expressed in Escherichia coli Rosetta (DE3) cells and the specific activity of purified Mpro was assessed by a FERT assay using a fluo...
Article
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Because of the emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different regions of the world, the battle with infectious coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has been seesawing. Therefore, the identification of antiviral drugs is of particular importance. In order to rapidly identify inhibit...
Article
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Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible and has caused a pandemic named coronavirus disease 2019 (COVID-19), which has quickly spread worldwide. Although several therapeutic agents have been evaluated or approved for the treatment of COVID-19 patients, efficacious antiviral agents are still la...
Article
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Cryptosporidium is a life-threating protozoan parasite belonging to the phylum Apicomplexa, which mainly causes gastroenteritis in a variety of vertebrate hosts. Currently, there is a re-emergence of Cryptosporidium infection; however, no fully effective drug or vaccine is available to treat Cryptosporidiosis. In the present study, to better unders...
Article
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Echinococcosis is a zoonotic parasitic disease that is highly endemic to the Qinghai province of China. Limited data are available on the prevalence of the causal pathogen, Echinococcus spp., in definitive hosts in this region. Thus, the aim of this study was to evaluate the prevalence of Echinococcus spp. in wild foxes and stray dogs in Qinghai pr...
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Background: Contrast-enhanced ultrasound (CEUS) can detect lesions hidden in inflammatory regions and find necrosis or areas of severe fibrosis within the lesion. This retrospective study aimed to compare the diagnostic accuracy of solid pancreatic lesions using percutaneous ultrasound (US)-guided fine-needle aspiration (FNA) with or without CEUS...
Article
The OPG/RANKL/RANK pathway is a promising target for the design of therapeutic agents used in the treatment of osteoporosis. E09241 with an N-methylpyridine-chlorofuranformamide structural skeleton was previously identified to decrease bone loss and thus protect against osteoporosis in ovariectomized rats through increasing osteoprotegerin (OPG) ex...
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Giardia duodenalis is a common zoonotic intestinal pathogen. It has been increasingly reported in humans and animals; however, genotyping information for G. duodenalis in captive animals is still limited. This study was conducted to assess the prevalence and multilocus genotyping of G. duodenalis in captive animals in zoological gardens in Shanghai...
Article
This study aimed at assessing the occurrence of twelve mycotoxins, including deoxynivalenol (DON) and its derivatives, 3- and 15-acetyl-deoxynivalenol (3-ADON and 15-ADON), nivalenol (NIV), zearalenone (ZEN), fumonisins (FB1, FB2 and FB3) and aflatoxins (AFB1, AFB2, AFG1 and AFG2) in 338 unprocessed wheat samples harvested in 2018 from China by hig...
Article
The emerging applications of electrochemical gas sensors (EGSs) in Internet of Things-enabled smart city and personal health electronics bring out a new challenge for common EGSs, such as alcohol fuel cell sensors (AFCSs) to reduce the dependence on a pricy Pt catalyst. Here, for the first time, we propose a low-cost novel N,S-codoped metal catalys...
Article
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Background and aims: Schistosomiasis japonica is a widespread human zoonotic disease, and in China, there are many patients with schistosomiasis suffering from liver fibrosis. Many studies have shown that natural killer (NK) cells could reduce the progression of hepatic fibrosis by directly killing hepatic stellate cells (HSCs). However, NK cells...
Article
N-(5-Chlorobenzo[d]oxazol-2-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamideox-amide has been identified as a potent inhibitor of Mtb H37Rv, with a minimum inhibitory concentration (MIC) of 0.42 μM. In this study, a series of substituted 2-acylamide-1,3-zole analogues were designed and synthesized, and their anti-Mtb activities were analyzed. In total,...
Article
Zinc-iodine redox flow batteries (ZIFBs) have emerged as promising energy storage systems due to their high-energy density. However, their practical use has been limited by their poor stability, low efficiency and high cost. In this work, we implemented a novel strategy to improve the performance and cyclability of ZIFBs, as well as decrease the ch...
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Cystic echinococcosis is a worldwide chronic zoonotic disease that threatens human health and animal husbandry. Exosome-like vesicles (ELVs) have emerged recently as mediators in the parasite–parasite intercommunication and parasite–host interactions. Exosome-like vesicles from parasites can transfer non-coding RNAs (ncRNAs) into host cells to regu...
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A controllable generation of oxygen gas during the decomposition of hydrogen peroxide by the microreactors made of tubular catalytic nanomembranes has recently attracted considerable attention. Catalytic microtubes play simultaneous roles of the oxygen bubble producing microreactors and oxygen bubble-driven micropumps. An autonomous pumping of pero...
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The demand for novel antibiotics is imperative for drug-resistant Gram-negative bacteria which causes diverse intractable infection disease in clinic. Here, a comprehensive screening was implemented to identify potential agents that disrupt the assembly of β-barrel outer-membrane proteins (OMPs) in the outer membrane (OM) of Gram-negative bacteria....
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TiO2 is a promising environment friendly, low cost, and high electrochemical performance material. However, impediments like high internal ion resistance and low electrical conductivity restrict its applications as electrode for supercapacitor. In the present work, atomic layer deposition was used to fabricate TiO2 nanomembranes (NMs) with accurate...
Article
Atomic‐scale design of interfacial structure is an intriguing but challenging approach to developing efficient heterogenous catalysts for bifunctional oxygen electrocatalysis. Herein, an exquisite triphasic interfacial structure featuring the encapsulation of FexNi alloy in a graphitic shell with a partial exposure of the FeOy thin‐layered surface...
Article
Background: Deep learning-based computer-aided diagnosis (CAD) is an important method in aiding diagnosis for radiologists. We investigated the accuracy of a deep learning-based CAD in classifying breast lesions with different histological types. Methods: A total of 448 breast lesions were detected on ultrasound (US) and classified by an experie...
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Background: This preliminary study aimed to examine the feasibility of sentinel lymph node biopsy (SLNB) using contrast-enhanced ultrasound (CEUS) vs. indocyanine green fluorescence (ICG), combined with blue dye in patients with breast cancer. Methods: This was a retrospective study of consecutive female patients with invasive stage I-III (based...
Preprint
Background To explore the potential value of S-Detect™, a high-end computer-assisted diagnosis (CAD) software system for residents-in-training. Methods Routine breast ultrasound (US) examinations were conducted and assessed by an experienced radiologist. Archived images of the lesions (including grayscale, color Doppler flow and elastography images...
Article
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Glioma, the most common primary malignancy in the brain, has high recurrence and lethality rates, and thus, elucidation of the molecular mechanisms of this incurable disease is urgently needed. Poly-pyrimidine tract binding protein (PTBP1, also known as hnRNP I), an RNA-binding protein, has various mechanisms to promote gliomagenesis. However, the...
Article
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The present work deals with a poly(vinyl alcohol)‐based membrane mixed with poly(4‐styrenesulfonic acid) to be used as a proton‐conducting solid‐state electrolyte in an electrochemical gas sensor for the detection of alcohol. A cross‐linking bonding semi‐interpenetrating network is formed between the polymer backbones, providing the membrane with s...
Article
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Amorphous TiO2 thin films were respectively annealed by 13.56 MHz radio frequency (RF) atmospheric pressure plasma at discharge powers of 40, 60, 80 W and thermal treatment at its corresponding substrate temperature (Ts). Ts was estimated through three measurement methods (thermocouple, Newton’s law of cooling and OH optical emission spectra simula...
Article
Rolled‐up catalytic Ti/Cr/Pt microtubes, consisting of inorganic nanomembranes integrated on‐chip, are used to generate oxygen microbubbles in solutions of hydrogen peroxide. Oxygen bubble parameters (frequency, radius and volumetric flow rate) are optimized in different concentrations of hydrogen peroxide and common dish soap. Increasing the aspec...
Article
In this paper, the dual-frequency atmospheric-pressure glow discharge is operated in helium with a small amount of oxygen. It is found that the plasma density increases, but the reactive atomic oxygen density decreases with high-frequency (HF) power. The plasma density also increases with low-frequency (LF) power, but it is weak as with HF power. H...
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For the ever-increasing demand for highly safe lithium-ion batteries (LIBs), the common sol-gel process provides heat-resistance to separators with an inorganic coating, where the adhesion to the separator is the key to safety and stability. In this paper, we present a SiO2.01C0.23Hx-coated polyethylene (PE) separator through a roll-to-roll atmosph...
Article
Three deposition modes of red atmospheric pressure plasma enhanced chemical vapor deposition were applied to study the influences of plasma discharge and the external substrate temperature on improving its crystallization: deposition in plasma red zone with post-heat annealing [Mode (a)], deposition outside plasma zone with a heated substrate [Mode...
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The highly oxidative operating conditions of rechargeable zinc–air batteries causes significant carbon‐support corrosion of bifunctional oxygen electrocatalysts. Here, a new strategy for the catalyst support design focusing on oxygen vacancy (OV)‐rich, low‐bandgap semiconductor is proposed. The OVs promote the electrical conductivity of the oxide s...
Article
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Totals of 158 corn and corn-based samples and 291 wheat and wheat-based samples from Shandong province, China in 2017 were analyzed for five mycotoxins including beauvericin (BEA), enniatin A (ENA), enniatin A1 (ENA1), enniatin B (ENB), and enniatin B1 (ENB1) by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). BEA was t...
Article
Introduction The emergence of drug-resistant Gram-negative bacteria is a serious clinical problem that causes increased morbidity and mortality. However, the slow discovery of new antibiotics is unable to meet the need for treating bacterial infections caused by drug-resistant strains. Lipopolysaccharide (LPS) is synthesized in the cytoplasm and tr...
Article
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Redox flow batteries are of particular interest because of the flexible power and energy storage originating from their unique architecture, but the low energy density has inhibited their widespread dissemination. In this work, a novel strategy of tuning the pH of the electrolyte environment is put forward to enhance battery voltage, and eventually...
Article
Although mammography (MG) has been widely used for breast cancer screening in the western world, over-diagnosis remains controversial. Milestone studies showed that ultrasound (US) was an effective primary screening test for breast cancer both in the western world and in China. US improves the sensitivity of screening in Chinese women who have dens...
Article
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Rechargeable zinc–air batteries (ZnABs) are attracting great interest due to their high theoretical specific energy, safety, and economic viability. However, their performance and large-scale practical applications are largely limited by poor durability and high overpotential on the air-cathode due to the slow kinetics of the oxygen reduction and e...
Article
Objective: To explore the feasibility of sentinel lymph node (SLN) identification by contrast-enhanced ultrasound (CEUS) in pre-operative breast cancer patients and the value of enhancement patterns for diagnosing lymph node metastases and characterising axillary nodal burden. Methods: 110 consecutive breast cancer patients were enrolled. Before...
Article
Dielectric barrier discharge (DBD) plasma was used to modify polyethylene terephthalate (PET) films with gradient roughness and homogenous surface chemistry. Based on asymmetric electrode arrangement, the spatial distribution of the plasma on the films surface was non-uniform, leading to the formation of typical three discharge regions (central zon...
Article
T-UCRs, a class of long non-coding RNAs that are transcribed from ultra-conserved regions (UCRs), might play an important role in development and diseases. However, the amount of T-UCRs that are conservatively expressed in the developing nervous systems of mice, monkeys and humans is still unknown. In this study, we screened the RNA sequence signal...
Article
The present study aimed to determine the value of endorectal ultrasound (ERUS) and magnetic resonance imaging (MRI) for T3 rectal cancer, and substaging of T3 rectal cancer by measuring the extent of mesorectal invasion (EMI). The clinical data of patients with rectal cancer who were admitted to the general surgical department of Peking Union Medic...
Article
In this study, polyethylene terephthalate (PET) substrate was successfully coated Al2O3 and TiO2 films by atomic layer deposition (ALD). The experiment results demonstrate that the Al2O3 can be deposited more efficiently than TiO2 on PET substrates. Further characterization on the coated substrates reveals that the density of hydroxyl –OH groups pl...
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A co-functionalized cellulose/GO proton-conducting solid electrolyte with threedimensional interpenetrating network structure is developed in an efficient and green strategy, and successfully applied in an electrochemical gas sensor for the detection of alcohol, namely an alcohol fuel cell sensor. With grafted sulfonic acid groups onto the surface...
Article
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There are a total of 30 strains including 27 strains of Aspergillus niger intended used in Chinese food industry, two strains used as control and one strain isolated from corn for fumonisin (FB) production on 3 media. It was found that FB2 production by A. niger was function-dependent and highly related to culture media, as well as incubation time....
Article
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Polo-like kinase 1 (Plk1) is a promising target for cancer therapy due to its essential role in cell division. In addition to a highly conserved kinase domain, Plk1 also contains a Polo-Box domain (PBD), which is essential for Plk1's subcellular localization and mitotic functions. We adopted a fluorescence polarization assay and identified a new Pl...
Article
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In this study, TiO2 and TiO2-ZnO nanomembranes were fabricated by atomic layer deposition using the three-dimensionally porous template and their photocatalytic properties were investigated. The nanomembranes were firstly deposited onto the surface of polyurethane porous sponge templates (sacrificial templates), followed by a calcination at 500 or...
Article
The discharge operation regime of pulse modulated atmospheric radio frequency (RF) glow discharge in helium is investigated on the duty cycle and frequency of modulation pulses. The characteristics of radio frequency discharge burst in terms of breakdown voltage, alpha(?)-gamma(?) mode transition voltage and current are demonstrated by the discharg...
Article
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Two-dimensional TiO2 nanosheets were synthesized by atomic layer deposition (ALD) on dissolvable sacrificial polymer layer. The photocatalytic performance of free-standing TiO2 nanosheets prepared with different numbers of ALD cycles (100, 300, 500, and 1000) were investigated by evaluating the degradation rates of methyl orange solutions. It is sh...
Article
Objective: To survey the fungi contamination of four kinds of feed ingredients in 2013- 2014 from parts of China. Methods: A total of 795 feed ingredients including soybean meal, cottonseed meal, wheat bran and distillers dried grains with soluble( DDGS) were collected from representative enterprises in different parts of China. Food safety nati...
Article
In this paper, polyimide (PI) films are modified using an atmospheric pressure plasma generated by a dielectric barrier discharge (DBD) in argon. Surface performance of PI film and its dependence on exposure time from 0 s to 300 s are investigated by dynamic water contact angle (WCA), field emission scanning electron microscopy (FESEM), and Fourier...
Article
Dyeing of PET materials by traditional methods presents several problems. Plasma technology has received enormous attention as a solution for the environmental problems related with textile surface modifications, and there has been a rapid development and commercialization of plasma technology over the past decade. In this work, the synergistic eff...
Article
Nanomembrane self-rolling offers the manufacture flexibility of 3D architectures for various applications in photonics, robotics, electronics, etc. Rolled-up oxide microtubes fabricated by both wet chemical etching and dry-releasing methods enable a broad range tuning of diameters (from 1 to 15 μm) and therefore same to their optical whispering gal...
Article
Full-text available
A free-standing sulfonic acid functionalized graphene oxide (fSGO)-based electrolyte film is prepared and used in an electrochemical gas sensor, an alcohol fuel cell sensor (AFCS), for the detection of alcohol. The fSGO electrolyte film-based AFCS detects ethanol vapor with excellent response, linearity, and sensitivity, since it possesses a high p...
Article
Polyethylene terephthalate (PET) fiber and textile is one of the largest synthetic polymer commodity in the world. The great energy consumption and pollution caused by the high temperature and pressure dyeing of PET fibers and fabrics with disperse dyes has been caused concern these years. In this study, an atmospheric pressure plasma with fine and...
Article
Rechargeable zinc–air batteries, having high energy densities and cost-effectiveness, are important environmentally-benign energy storage solutions. Here we developed a facile strategy for fabricating a nanoporous alkaline-exchange electrolyte membrane from natural cellulose nanofibres, exhibiting high ionic-conductivity and water retention as well...
Article
The study described here sought to identify specific ultrasound (US) automated breast volume scanning (ABVS) features that distinguish benign from malignant lesions. Medical records of 750 patients with 792 breast lesions were retrospectively reviewed. Of the 750 patients, 101 with 122 cystic lesions were included in this study, and the results ABV...