Jie Wang

Ebola virus disease (EVD) caused by Zaire Ebolavirus (EBOV) infection is a major threat to public health in Africa and even worldwide, due to its extremely high mortality rate. However, there are still no effective antiviral therapies that can completely cure EVD. A comprehensive understanding of virus-host interactions would be beneficial for deve...

Although the damped triboelectric nanogenerator with an assisted pendulum and spring structure has the significant advantages in harvesting water‐wave energy, these designs have reduced the space utilization of devices. Meanwhile, the indispensable and high‐weight power take‐off device in the related researches greatly also reduces the space utiliz...

To investigate the infection of children with respiratory tract infection in Hangzhou from 2019 to 2023, and to explore the epidemiological characteristics of respiratory tract virus infection before and after the prevalence of novel coronavirus. A retrospective analysis was conducted on oral and pharyngeal swabs from 302,680 children with acute re...

Map matching is crucial to facilitating location-based services, and recent advancements in map matching have demonstrated excellent performance with high-quality data. However, the use of low-precision devices often introduces high measurement noise, and the slow update rate of maps may result in errors in digital maps. Consequently, multiple type...

This review systematically discusses performance limiting factors and materials-related strategies for high-performance AC-TENGs and DC-TENGs.

Background Improving angiogenesis in the ischemic myocardium is a therapeutic strategy for preventing, reducing, and repairing myocardial injury of coronary artery disease (CAD). Panax notoginseng saponins (PNS) have been widely used in the clinical treatment of cardiovascular diseases, demonstrating excellent efficacy, and can potentially improve...

Triboelectric nanogenerators (TENGs), among the most simple and efficient means to harvest mechanical energy, have great potential in renewable energy utilization. While the output performance of TENGs is still not high enough, which limits its practical application. Here, a poly(vinylidene fluoride) (PVDF)/fluorinated ethylene propylene nanopartic...

Objective Inflammation and nutritional status are closely associated with the mortality risk of survivors of cardio-cerebrovascular events. This study aims to evaluate the relationship between inflammation and nutritional indices and mortality among, identifying the most predictive indices. Methods This study included cohort data of the survivors...

The recent years have witnessed a surge in the development of traffic flow prediction methods, often deployed on cloud platforms to offer predictive services for entire transportation networks. However, the processes of training and executing a model for the entire traffic network are both time-consuming and computationally expensive. As a result,...

Triboelectric nanogenerator (TENG) harvesting ocean wave energy is an effective method to alleviate the energy crisis. However, the breakdown phenomenon is ubiquitous for the TENG with a large area of dielectric layer, which not only limits the output and reliability but also highly risks the device failure. Here, a self‐recovery TENG (SR‐TENG) fea...

Triboelectric nanogenerator (TENG) offers a novel approach for converting high‐entropy mechanical energy into electrical energy, yet achieving high charge density remains critical. Optimizations using dielectrics with high specific capacitance have mitigated air breakdown, but charge loss within dielectrics persists as a limiting factor. Here, base...

Acoustic sensor‐based human–machine interaction (HMI) plays a crucial role in natural and efficient communication in intelligent robots. However, accurately identifying and tracking omnidirectional sound sources, especially in noisy environments still remains a notable challenge. Here, a self‐powered triboelectric stereo acoustic sensor (SAS) with...

Non‐pharmaceutical interventions (NPIs) implemented to control SARS‐CoV‐2 have significantly influenced the activity of respiratory pathogens. This study investigated epidemiological changes among hospitalized patients with respiratory syncytial virus (RSV) before (2017–2019) and during (2020–2022) the COVID‐19 pandemic in Hangzhou, China. We also...

Cell death constitutes a critical component of the pathophysiology of cardiovascular diseases. A growing array of non-apoptotic forms of regulated cell death (RCD)—such as necroptosis, ferroptosis, pyroptosis, and cuproptosis—has been identified and is intimately linked to various cardiovascular conditions. These forms of RCD are governed by geneti...

Background: Aging is characterized by a decline in the adaptability and resistance of the body. In this study, Bushen Kangshuai Granules (BKG), as a kind of Chinese herbal formula, was developed and shown to alleviate aging-related symptoms. Methods: Self-controlled study combined with RNA-seq and metabonomics were used to expound the efficacy and...

Although a combination of immunoprophylaxis and antiviral therapy can effectively prevent mother-to-child transmission (MTCT) of hepatitis B virus (HBV), a considerable number of infants born to highly viremic mothers still develop occult HBV infection (OBI). To uncover the virological factor and risk predictor for OBI in infants, we found that the...

Genetic code expansion has emerged as a powerful tool for precisely introducing unnatural chemical structures into proteins to improve their catalytic functions. Given the high catalytic propensity of histidine in the enzyme pocket, increasing the chemical diversity of catalytic histidine could result in new characteristics of biocatalysts. Herein,...

Harvesting mechanical energy through triboelectric nanogenerators (TENGs) for effectively purifying water, self‐powered wastewater treatment system presents a promising solution to address both energy and environmental crises. However, issues such as side‐discharge and wear, resulting from interfacial charge transfer, seriously hinder the output an...

Direct‐current triboelectric nanogenerators (DC‐TENGs) arising from electrostatic breakdown have garnered significant attention due to their advantages of rectification‐free operation, constant current output, and high output power density. Previous studies have primarily concentrated on improving its performance through structural design and param...

Spontaneously occurred electrostatic breakdown releases enormous energy, but harnessing the energy remains a notable challenge due to its irregularity and instantaneity. Here, we propose a revolutionary method that effectively harvests the energy of dynamic interfacial electrostatic breakdown by simply imbedding a conductive wire (diameter, 25 micr...

Background Coronary heart disease (CHD) is representative of cardiovascular disease and the leading cause of death in humans. Previous studies have shown that kidney disease is associated with CHD, and current treatment options that can improve both cardiac and renal functions still have some limitations. The traditional Chinese medicine Bu-Shen-Hu...

Mechanical energy harvesting using triboelectric nanogenerators is a highly desirable and sustainable method for the reliable power supply of widely distributed electronics in the new era; however, its practical viability is seriously challenged by the limited performance because of the inevitable side-discharge and low Coulombic-efficiency issues...

The triboelectric nanogenerator (TENG) holds significant potential for applications in energy harvesting and environment monitoring. However, a notable challenge lies in developing a combined system capable of efficiently harvesting energy and providing real‐time self‐powered sensing. Here, a combined wind energy harvesting and speed sensing (EHSS)...

Triboelectric nanogenerator (TENG) is a promising solution to harvest the low‐frequency, low‐actuation‐force, and high‐entropy droplet energy. Conventional attempts mainly focus on maximizing electrostatic energy harvest on the liquid‐solid surface, but enormous kinetic energy of droplet hitting the substrate is directly dissipated, limiting the ou...

Human health and the environment face significant challenges of air pollution, which is predominantly caused by PM2.5 or PM10 particles. Existing control methods often require elevated energy consumption or bulky high‐voltage electrical equipment. To overcome these limitations, a self‐powered, convenient, and compact direct current high‐voltage tri...

SRY‐box transcription factor 6 ( SOX6 ) is a member of the SOX gene family and inhibits the proliferation of cervical cancer cells by inducing cell cycle arrest. However, the final cell fate and significance of these cell‐cycle‐arrested cervical cancer cells induced by SOX6 remains unclear. Here, we report that SOX6 inhibits the proliferation of ce...

Accurate measurement of complicated multiphase flow is crucial to the safety and efficiency of petroleum and chemical industrial facilities. However, the existing multiphase flow detection techniques are not applicable to pipelines in remote regions including deserts or deep seas, due to the high cost of providing a stable power supply. Herein, a s...

Objective: Post-myocardial infarction heart failure (post-MI HF) is a prevalent cardiovascular disease. The study aims to preliminarily explore the current research status and development trends in the field of post-MI HF, providing reference ideas and methods for clinical and scientific research. Methods: Publications related to post-MI HF from 20...

Cellular context is crucial for understanding the complex and dynamic kinase functions in health and disease. Systematic dissection of kinase-mediated cellular processes requires rapid and precise stimulation (‘pulse’) of a kinase of interest, as well as global and in-depth characterization (‘chase’) of the perturbed proteome under living condition...

Triboelectric nanogenerator (TENG) has aroused great interest in high-entropy energy field for its ability to convert environmental mechanical energy into electricity. However, TENG technology has typically focused on the performance...

Ultrahigh charge density (8.6 mC m ⁻² ) and energy density (0.808 J m ⁻² per cycle) are achieved in triboelectric nanogenerators by suppressing air breakdown via triboelectric polymer design.

Triboelectric nanogenerators (TENGs), serving as an innovative energy harvesting technology, have garnered significant attention and demonstrated promising potential applications across Internet of Things and Artificial Intelligence. However, developing an efficient...

Charge generation and charge decay are two essential factors that determine the surface charge density of a triboelectric nanogenerator (TENG). However, research mainly focuses on boosting charge generation, and little attention is paid to suppressing charge decay. Here, a strategy of suppressing charge decay, including the air breakdown and dielec...

With the continuous rise of environmental pollution and energy crisis, the global energy revolution is risen. Development of renewable blue energy based on the emerging promising triboelectric nanogenerators (TENG) has become an important direction of future energy development. The solid–liquid contact triboelectric nanogenerator (TENG) has the adv...

Objective This aim of this study is to screen the differential molecules of kidney deficiency and blood stasis (KDBS) syndrome in coronary heart disease by high-throughput sequencing. In addition, the study aims to verify the alterations in the expression levels of miR-4685-3p and its regulated downstream, namely, C1QC, C4, and C5, using quantitati...

Energy harvesters based on the tribovoltaic effect that can convert mechanical energy into electricity offer a potential solution for the energy supply of decentralized sensors. However, a substantial disparity in output current, exceeding 106 times, exists between micro- and macro-contact tribovoltaic nanogenerators (TVNGs). To tackle this challen...

Tribovoltaic nanogenerators (TVNGs) have the characteristics of high current density, low matched impedance and continuous output, which is expected to solve the problem of power supply for small electronic devices. However, wear occurrence in friction interface will seriously reduce the performance of TVNGs as well as lifetime. Here, we employ MXe...

Traditional Chinese medicine (TCM) with a long history in China has demonstrated unique advantages in treating a variety of cardiovascular diseases, with promising prospects. We exemplify the TCM advantages with 3 major cardiovascular diseases: coronary heart disease, hypertension, and chronic heart failure. With both national and international gui...

To meet the requirements of power grid operation control, constructing an extensive sensor network in the power grid is a future development trend. However, due to the high cost, the difficulty of continuous power supply for a long time, the large amount of energy consumption, and the environmental problems caused by abandoned batteries, the tradit...

The core protein allosteric modulators (CpAMs) have shown great potential as highly effective antiviral drugs against hepatitis B virus (HBV) in preclinical studies and clinical trials. In this study, we evaluated a small molecule compound called QL-007, which could potentially influence capsid assembly, using HBV replicated and susceptible cell mo...

Purpose: Viral myocarditis (VMC) is a life-threatening disease that can affect all ages and genders, with middle-aged adults being particularly susceptible. Numerous systematic reviews have been conducted to investigate the efficacy and safety of Chinese herbal medicine (CHM) in treating adult viral myocarditis (AVM). The objective of this study w...

Due to the simple installation and convenient maintenance, the floating water wave energy harvesting devices have significant economic advantages. Mass power density is the most important index to evaluate the advancement of floating wave energy harvesting devices. Herein, a self‐adaptive rotating triboelectric nanogenerator (SR‐TENG) with a compou...

Site-specific protein decaging by light has become an effective approach for in situ manipulation of protein activities in a gain-of-function fashion. Although successful decaging of amino acid side chains of Lys, Tyr, Cys, and Glu has been demonstrated, this strategy has not been extended to aspartic acid (Asp), an essential amino acid residue wit...

Acute myocardial infarction (MI), despite significant progress in its treatment, remains a leading cause of chronic heart failure and cardiovascular events such as cardiac arrest. Promoting angiogenesis in the myocardial tissue after MI to restore blood flow in the ischemic and hypoxic tissue is considered an effective treatment strategy. The repai...

Objective: Coronary heart disease, a prevalent cardiovascular disorder, has a well-established pathogenesis. However, uncertainty exists regarding the cellular response's chemical process. miRNAs are essential in silencing target genes and reducing the synthesis of corresponding proteins, thereby influencing cell functions. This study aims to explo...

The electrification of transportation in the past few decades has sparked the retirement of lithium‐ion batteries (LIBs) which hinders sustainability derived from environmental impact and valuable elements loss through improper disposal. The challenges of recycling spent LIB are contamination, complicated processes, massive chemical/energy consumpt...

Triboelectric nanogenerators (TENGs) have received intense attention due to their broad application prospects in the new era of internet of things (IoTs) as distributed power sources and self‐powered sensors. Advanced materials are vital components for TENGs, which decide their comprehensive performance and application scenarios, opening up the opp...

Background The distribution of ACE2 and accessory proteases (ANAD17 and CTSL) in cardiovascular tissue and the host cell receptor binding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are crucial to understanding the virus’s cell invasion, which may play a significant role in determining the viral tropism and its clinical manifest...

Online map matching is essential for some location-based services, such as car navigation. However, due to GPS measurement errors and/or the lack of sufficient information, the performance of most existing online algorithms will degrade in the increasingly complex traffic environment. In this paper, we propose an adaptive online map matching algori...

Direct-current triboelectric nanogenerator (DC-TENG) arising from electrostatic breakdown exhibits unique merits over conventional alternating-current TENGs, such as the constant-current output and high output charge density. The selection of appropriate triboelectric material pair (TMP) is important for improving its performance. Here, we propose...

Traditional Chinese medicine (TCM) has been practiced for thousands of years with clinical efficacy. Natural products and their effective agents such as artemisinin and paclitaxel have saved millions of lives worldwide. Artificial intelligence is being increasingly deployed in TCM. By summarizing the principles and processes of deep learning and tr...

The development of the Internet of Things (IoT) and artificial intelligence has accompanied the evolution of energy demand and structure in the new era, and the power sources for billions of distributed electronics and sensors have aroused worldwide interest. As an alternative energy harvesting technology, triboelectric nanogenerators (TENGs) have...

With the intrinsic characters of high voltage and low current, triboelectric nanogenerators (TENGs) serving as green high voltage (HV) power source exhibit excellent practicability and safety compared to traditional HV power sources. To further simplify the TENG‐based HV power source system, a single electrode mode TENG (SE‐TENG) with simple wiring...

Backgrounds Dyslipidemia is a prominent risk factor for cardiovascular diseases and one of the primary independent modifiable factors of diabetes and stroke. Statins can significantly improve the prognosis of dyslipidemia, but its side effects cannot be ignored. Traditional Chinese Medicine (TCM) has been used in clinical practice for more than 200...

This study aimed to analyze the biological foundation and biomarkers of stable coronary heart disease(CHD) with phlegm and blood stasis(PBS) syndrome based on RNA-seq and network pharmacology. Peripheral blood nucleated cells from five CHD patients with PBS syndrome, five CHD patients with non-PBS syndrome, and five healthy adults were collected fo...

The ocean, as one of the most important areas for human production and living, plays a vital role in transportation, food production, and energy supply. However, it is greatly desired to develop relevant advanced technologies to achieve efficient and safe ocean exploitation and utilization. The advanced triboelectric nanogenerator (TENG), which can...

Mother-to-child transmission (MTCT) is still the main route of hepatitis B virus (HBV) infection. However, the virological factors affecting HBV MTCT have not been fully elucidated. In this study, based on a prospective cohort of mother-infant pairs with positive maternal hepatitis B surface antigen (HBsAg), we found that the average nucleotide mut...

Mimicking the multilayered structure of blood vessels and constructing a porous inner surface are two effective approaches to achieve mechanical matching and rapid endothelialization to reduce occlusion in small-diameter vascular grafts. However, the fabrication processes are complex and time consuming, thus complicating the fabrication of personal...

Background Antibodies induced by viral infection can not only prevent subsequent virus infection, but can also mediate pathological injury following infection. Therefore, understanding the B-cell receptor (BCR) repertoire of either specific neutralizing or pathological antibodies from patients convalescing from Coronavirus disease 2019 (COVID-19) i...

Background and Aims Occult HBV infection (OBI) in children has proven to be associated with their immune response to hepatitis B vaccine (HepB). This study aimed to investigate the effect of a booster HepB on OBI, which is rarely investigated. Methods This study enrolled 236 maternal HBsAg-positive children who were followed up annually until 8 ye...

Synthetic hydrogels have made great progress in mechanical performance. But it is still a challenge to combine adequate stiffness, strength, and toughness in a single hydrogel. Herein, ultra-stiff, strong, and...

Triboelectric nanogenerator (TENG) has attracted broad attention owing to its potential applications in the internet of things era. However, an effective power management strategy to enable maximum energy extraction from...

A self-powered system composed of an electrochemical recycling reactor and a triboelectric nanogenerator is proposed for recycling spent lithium-ion battery with the advantages of high purity, self-powering, simplified procedure, and high profit.