Jianwei Li

Jianwei Li
University of Turku | UTU · Department of Chemistry

PhD

About

41
Publications
2,381
Reads
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982
Citations
Additional affiliations
August 2014 - July 2016
University of Oxford
Position
  • PostDoc Position
October 2009 - March 2014
University of Groningen
Position
  • PhD Student
September 2006 - June 2009
Nankai University
Position
  • Master's Student

Publications

Publications (41)
Article
Full-text available
Plastics are one of the most widely used polymeric materials. However, they are often undegradable and non‐recyclable due to the very stable covalent bonds of macromolecules, causing environmental pollution and health problems. Here, we report that liquid‐liquid phase separation (LLPS) could drive the formation of robust, stable, and sustainable pl...
Article
Plastics are one of the most widely used polymeric materials. However, they are often undegradable and non‐recyclable due to the very stable covalent bonds of macromolecules, causing environmental pollution and health problems. Here, we report that liquid‐liquid phase separation (LLPS) could drive the formation of robust, stable, and sustainable pl...
Article
Curcuminoids have been extensively investigated as metal ion probes, but the intrinsic aggregation-caused-quenching (ACQ) characteristic of curcumin would hinder their applications in aqueous solution. Fortunately, tetraphenylethylene (TPE) could endow the compounds with aggregation-induced emission (AIE)/aggregation-induced enhanced emission (AIEE...
Preprint
Full-text available
Supramolecular polymers self-assembled by small molecules are a type of new material with adaptive and biocompatible properties. However, the mechanical property of these materials is always weak, impeding their applications in practice. Here, we reported that coacervation can be used to explore robust and stable bulk materials without the compromi...
Article
Doping sulfur into TiO2 can narrow the bandgap of the native TiO2, offering an efficient way to improve its photocatalytic efficiency and extend its absorption from the ultraviolet to the...
Article
Pillararenes are a new type of supramolecular hosts, and they have been widely applied in drug delivery, catalysis, separation process, and sensors. However, they have rarely been used to produce hydrogen. Here, we report that pillararenes were used as functional molecules to explore photocatalysts and efficiently promoted hydrogen production from...
Article
Titanium dioxide (TiO2) has been limited in photocatalysis due to its wide band gap (3.2 eV) and limited absorption in the ultraviolet range. Therefore, organic components have been introduced to hybrid with TiO2 for enhanced photocatalytic efficiency under visible light. Here, we report that benzo[1,2-b:4,5-b']dithiophene polymer was an ideal orga...
Article
Room temperature phosphorescent (RTP) materials have a variety of applications ranging from bio-imaging, optoelectronic devices to information security protection. However, the preparation procedures for these materials are always tedious and time-consuming. Here, we report a micro-wave approach to prepare RTP carbon dots (CDs) in only 8 min. The m...
Article
Full-text available
Inspired by the lock and key principle, the development of supramolecular macrocyclic chemistry has promoted the prosperous growth of host-guest chemistry. The updated induced-fit and conformation selection model spurred the emerging research on responsive macrocycles (RMs). This review introduces RMs, covering their design, synthesis and applicati...
Article
Molecular self‐assembly has been widely used to develop nanocarriers for drug delivery; however, most have unsatisfactory drug loading capacity (DLC) and the dilemma between stimuli‐responsiveness and stability, stagnating their translational process. Here we overcame these drawbacks using dynamic combinatorial chemistry. A carrier molecule was spo...
Article
Dynamic combinatorial chemistry was employed to explore an ideal carrier molecule for anti‐cancer drug delivery. Driven by thermodynamics, the carrier molecule was quantitatively yielded by its co‐self‐assembly with a template and a drug doxorubicin (DOX). The self‐assembled nanocarrier with a drug‐loading content of 40 % was stable yet pH‐ and red...
Article
Full-text available
Dynamic combinatorial chemistry (DCC) is a powerful approach for creating complex chemical systems, giving access to the studies of complexity and exploration of functionality in synthetic systems. However, compared with more advanced living systems, the man‐made chemical systems are still less functional, due to their limited complexity and insuff...
Article
Full-text available
The specific interactions responsible for molecular recognition play a crucial role in the fundamental functions of biological systems. Mimicking these interactions remains one of the overriding challenges for advances in both fundamental research in biochemistry and applications in material science. However, current molecular recognition systems b...
Article
Fluorescent nanomaterials have gained momentum due to their specific properties and promising applications in various fields. Molybdenum disulfide quantum dots (MoS 2 QDs) are emerging as a new class of fluorescent nanomaterials that have generated tremendous research interests due to their unique optical properties and good biocompatibility. In th...
Article
Fluorescent nanomaterials have gained momentum due to their specific properties and promising applications in various fields. Molybdenum disulfide quantum dots (MoS2 QDs) are emerging as a new class of fluorescent nanomaterials that have generated tremendous research interests due to their unique optical properties and good biocompatibility. In thi...
Article
Full-text available
Assembly processes can drive the selection of self-assembling molecules in dynamic combinatorial libraries, yielding self-synthesizing materials. We now show how such selection in a dynamic combinatorial library made from an amphiphilic building block which, by itself, assembles into micelles, can yield membranous aggregates ranging from vesicles t...
Article
Water molecules always quench fluorescence, limiting the practical application of fluorophores in bio-imaging. Probes developed from the well-establised Aggregation Induced Emission (AIE) effects seem to be able to overcome the challenge. However, the background interference issue has lagged the development of the field for a long time. Herein, we...
Article
Full-text available
Protein engineering has been used to remodel pores for applications in biotechnology. For example, the heptameric α-hemolysin pore (αHL) has been engineered to form a nanoreactor to study covalent chemistry at the single-molecule level. Previous work has been confined largely to the chemistry of cysteine side-chains, or in one instance to an irreve...
Article
Self-assembly of a specific member of a dynamic combinatorial library (DCL) may lead to self-replication of this molecule. However, if the concentration of the potential replicator in the DCL fails to exceed its critical aggregation concentration (CAC) self-replication will not occur. We now show how addition of a template can raise the concentrati...
Article
Allosteric synthetic receptors are difficult to access by design. Herein we report a dynamic combinatorial strategy towards such systems based on the simultaneous use of two different templates. Through a process of simultaneous casting (the assembly of a library member around a template) and molding (the assembly of a library member inside the bin...
Article
Allosteric synthetic receptors are difficult to access by design. Herein we report a dynamic combinatorial strategy towards such systems based on the simultaneous use of two different templates. Through a process of simultaneous casting (the assembly of a library member around a template) and molding (the assembly of a library member inside the bin...
Article
New methodology for making novel materials is highly desirable. Here, an “ingredients” approach to functional self-assembled hydrogels was developed. By designing a building block to contain the right ingredients, a multi-responsive, self-assembled hydrogel was obtained through a process of template-induced self-synthesis in a dynamic combinatorial...
Article
A new azobenzene-based dithiol building block was developed which, upon oxidation, forms predominantly a [2]catenane consisting of two interlocked trimers. In the presence of cyclodextrin templates a series of [2] and [3]catenanes was formed instead. We developed a method that enabled estimating the equilibrium constants for catenation in all of th...
Article
Dynamic Combinatorial Chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other. Dynamic combinatorial libraries (DCLs) are powerful tools for discovering the unexpected and have given rise to many fascinating molecules, ranging from interlocked structure...
Article
Stacks of macrocycles, assembled using reversible disulfide-bond formation, are covalently captured by photoinitiated exchange of disulfide bonds, inducing the formation of hydrogels. This strategy allows access to structures beyond the thermodynamic minima traditionally targeted by dynamic combinatorial chemistry.
Article
Three anion receptors based on urea: 1N, N′-bis-(p-nitrophenylaminocarbonyl)-Hydrazine, 2N, N′-bis-(p-nitrophenylaminocar-bonyl)-ethylenediamine and 3N, N′-bis-(p-nitrophenylaminocarbonyl)-1, 3-propane-diamine are designed and synthesized. Studies of UV–vis spectra presented that 1 was an excellent sensor of F− and 2 was sensitive to H2PO4 −. Unfor...
Article
A colorimetric sensor 1,N,N'-di-(2-hydroxy-5-(phenldiazenyl)benzaldehyde)-1,3-diiminothiourea for acetate in DMSO and 9/1 DMSO/H(2)O (v/v) mixtures was designed and synthesized. The binding ability evaluated by UV-vis experiment reveals that sensor 1 can selectively recognize acetate. In addition, the color changes induced by anions can provide a w...
Article
A novel and efficient receptor based on the phenylhydrazone derivatives is successfully developed and applied to the acetate anion recognition, indicating that the origin of special preference for acetate (AcO−) anion maybe the structure well matching between the host and the guest. The sensor changes its color so obviously on addition of the aceta...
Article
Full-text available
An anion recognition receptor, a kind of thiourea derivative, was designed and synthesized by combining indoline-2,3-dione and 1,3-diaminothiourea. The anion recognition can be easily monitored by anion complexation induced changes in UV-vis absorption spectra. In particular, the binding ratio between the receptor and fluoride is 1:2 but in the cas...
Article
A sensitive colorimetric sensor (1) based on 4,5-dinitrobenzene-1,2-diamine was designed and synthesized. Binding of anions such as AcO(-), F(-) and H(2)PO(4)(-) results in a notable change in the visible region of spectrum (an approximately 90nm red shift), which can be detected by the 'naked-eye'. Furthermore, the binding ability was evaluated by...
Article
2′-(p-nitrophenyl)-imidazol[4′,5′-f]-1,10-phenanthroline[5,6-f] (1) and its complex (2) were synthesised and studied for the anion sensing by UV–vis, fluorescence and ¹H NMR titration experiments. Compounds 1 and 2 exhibited obviously different changes between reactions with AcO− , F− , and with other halogens, i.e. Cl− , Br− , I− , in any of the...
Article
An anion receptor was synthesized with ferrocene as binding frame. Anion recognition can be monitored by anion complexation-induced changes in UV-vis absorption spectra. Interaction between the receptor and acetate was described on the basis of H NMR experiments.
Article
A novel turn-on fluorescent and colorimetric sensor, N-(4′-nitrophenyl)-2-oxo-6-(phenylazo)-2H-chromene-3-carbohydrazide (1), for fluoride in dimethyl sulfoxide (DMSO) was designed and synthesized. The binding ability evaluated by UV–vis and fluorescence titration experiments reveals that 1 can selectively recognize fluoride. In particular, additio...
Article
A series of artificial receptors, based on a sulfonamido system, have been designed and synthesized. The interaction of these receptors with biologically important anions was determined by UV-vis, (1)H NMR titration and electrochemical experiments. Results indicate that these receptors show high recognition abilities for fluoride (F(-)) or acetate...
Article
A new and simple salicylaldehyde-based sensor 1 designed for fluoride sensing has been investigated in DMSO and even in the 9/1 DMSO/H(2)O (v/v) mixtures. The affinity constants of receptor 1 for anionic species in the 9/1 DMSO/H(2)O (v/v) reveal that it is sensitive to F. Also, the color changes induced by anions can provide a way of detection by...
Article
A new anion receptor: 1,1′-di-(2″,4″-di-nitrophenylhydrazino-β-carbonyl)-ferrocene (1) based on ferrocene has been designed and synthesized as a highly colorimetric and electrochemical sensitive sensor for F−. The binding mode with F− was further investigated by UV–vis titration and 1H NMR titration experiments. In addition, the cyclic voltammetry...
Article
A novel receptor based on phenylhydrazone derivative was developed and applied to the binding anion, showing a common preference for acetate (AcO−) ion, and the preference was related to structure matching between the host and the guest. The receptor exhibited a dramatic color change upon the addition of acetate ions so that we could finish anion r...
Article
A new compound, 1,1′-di-(p-nitrophenylhydrazino-β-carbonyl)-ferrocene (1) was designed as an anion receptor based on its hydrogen bonding interaction with anions. Investigation of UV–vis spectra showed that it was an excellent optical sensors for F−. Furthermore, the nature of interaction between it and F− was investigated by 1H NMR titration exper...
Article
A novel 1,3-di(2′,4′-dinitrophenylhydrazone)-5-nitrobenzene receptor has been synthesized by simple steps with good yields. The anion recognition properties were studied by ultraviolet-visible (UV-Vis) spectroscopy. The results showed that the receptor had a higher affinity to F−, CH3COO− and H2PO4−, but no evident binding with Cl−, Br−, and I−. Up...

Questions

Question (1)
Question
Dear colleagues,
We just prepared a gel-like material. However, when we checked its viscoelasticity, its loss modulus was higher than its storage modulus. Normally, if loss modulus is smaller than the storage modulus, the material is defined as a gel. So, I am wondering in our case, how to define such materials? Is it common to get such a material that looks like a gel, but its modulus does not consist with the gel definition? Just curiously, are there materials in nature whose loss modulus is higher than its storage modulus?
Many thanks and with best wishes,
Jianwei

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