Jianping Liu

Beijing University of Chinese Medicine · Centre for Evidence-Based Chinese Medicine

Introduction Chronic obstructive pulmonary disease (COPD) represents one of the leading causes of death worldwide. Published clinical trials suggest that the Chinese patent herbal medicine Shufeng Jiedu capsule (SFJD) is safe and may be effective for treating acute exacerbations of COPD (AECOPD). However, these effects have been reported with low o...

Objectives To evaluate the effectiveness and potential mechanism of traditional Chinese medicine Jiawei-Xiaoyao-San (JWXYS) as an adjunct or mono- therapy for antithyroid drugs (ATDs) in the treatment of hyperthyroidism. Methods Eight databases and three trial registries were searched from inception until May 2023. Randomized controlled trials (RC...

Objective To evaluate the effectiveness and safety of Linggui Zhugan decoction (LZD) as an adjunct treatment of premature contraction in patients with coronary heart disease.Methods PubMed, Embase, Web of Science, ClinicalTrials.gov Cochrane Library, Chinese Knowledge Infrastructure, Wanfang database, Sino Med, and VIP database were searched from i...

Background Psychological risk factors have been recognised as potential, modifiable risk factors in the development and progression of cardiovascular disease (CVD). Tai Chi, a mind-body exercise, has the potential to improve psychological well-being and quality of life. We aim to assess the effects and safety of Tai Chi on psychological well-being...

Background: Diarrhea is a ubiquitous digestive system disease, leading to loss of fluid and electrolytes, and may be life-threatening, especially in children and adults who are immunosuppressed or malnourished. Berberine has a broad-spectrum antibiotic activity and is very widely used to treat diarrhea in China. No systematic review has been carri...

Background The reliability of results can be compromised when subsets of participants who remain on a study differ from those who drop out. Although recent studies have investigated approaches for improving compliance, there has been very little investigation of process factors, regardless of the type of literature and the publication date. factors...

Background: The reliability of results can be compromised when subsets of participants who remain on a study differ from those who drop out. Although recent studies have investigated strategies for improving compliance and retention , there has been very little investigation of process factors, regardless of the type of literature and the publicati...

Background: This is the second part of a large spectrum systematic review which aims to identify and assess the evidence for the efficacy of non-pharmacological acupuncture techniques in the treatment of chronic obstructive pulmonary disease (COPD). The results of all techniques except for filiform needle are described in this publication. Method...

Objectives To investigate the consistency of adverse events (AEs) and adverse drug reactions (ADRs) reported in the literature, monitoring and social media data. Methods Using one Chinese patent medicine-Cordyceps sinensis extracts (CSE) as an example, we obtained safety data from the national monitoring system (July 2002 to February 2016), litera...

As a noninvasive technique, transcranial sonography (TCS) of substantia nigra (SN) has gradually showed its effectiveness not only in diagnosis but also in understanding clinical features of Parkinson’s Disease (PD). This study aimed to further evaluate TCS for clinical diagnosis of PD, and to explore the association between sonographic manifestati...

Objective: To investigate the efficacy and safety of Traditional Chinese Medicine (TCM) therapy combined with ultraviolet B light therapy in the treatment of moderate-to-severe psoriasis. Methods: Patients with moderate-to-severe psoriasis (skin lesion area > 10% of the body surface area) for 2 consecutive years were treated with TCM (oral and e...

Background: This is the first part of a larger spectrum systematic review which aims to identify and evaluates the effectiveness of all different non-pharmacological acupuncture techniques used for COPD. In this first publication, we describe the results of filiform needle acupuncture METHODS: Randomised controlled trials up to May 2019 were searc...

Selective serotonin reuptake inhibitors (SSRIs) are first-line antidepressants, however, only around 60% of patients could benefit from them. Acupuncture is supported by insufficient evidence to help with symptom relieving and SSRIs tolerance. This pragmatic randomized controlled trial compared SSRIs alone versus SSRIs together with manual acupunct...

Objectives: To explore doctors' knowledge, willingness, concerns and the countermeasures to the most stringent antimicrobial stewardship regulations of China which implemented in August 2012. Design: Cross-sectional survey. A pretested 32-point structured questionnaire was distributed to doctors by sending a web link via the mobile phone applica...

Background Herbal remedies have been widely utilized in treating chronic hepatitis C (CHC) worldwide. Selecting appropriate outcomes to reflect both beneficial and harmful effects is a crucial step in designing randomized controlled trials (RCTs). This study evaluated the outcomes reported in RCTs on herbal remedies for CHC with comparison to the c...

Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women. Clomiphene is regarded as the first-line medical treatment for ovulation induction in PCOS patients and acupuncture is often used as an alternative and complementary treatment for fertility issues such as those associated with PCOS. The effica...

Summary Eye-acupuncture, as a part of Chinese acupuncture, aims to treat diseases by needling or other stimulating methods around the orbital, which could be used in managing pain related disorders. To reveal its publishing situations for pain relief, a systematical collection of all clinical studies on eye-acupuncture for pain has been conducted....

Objective: To compare clinical practice guideline recommendations on the use of oral patent Traditional Chinese Medicines (PTCMs) for uncomplicated acute lower respiratory tract infections (ALRTIs) in adults with the existing evidence using results of a systematic review of randomized controlled trials (RCTs). Methods: A systematic review on RCT...

Background: As a multisystemic neurodegenerative disorder, Parkinson disease (PD) has a broad spectrum of symptoms including motor and nonmotor symptoms (NMS). As shown in studies, NMS can also impact patient's quality of life, and many of them often go untreated. Chinese herbal medicines with multiconstituent may alleviate NMS in PD patients. Thi...

Introduction Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. Psychological risk factors such as stress, anxiety and depression are known to play a significant and independent role in the development and progression of CVD and its risk factors. Tai Chi has been reported to be potentially effective for health and...

Acupuncture is used to induce ovulation in some women with polycystic ovary syndrome, without supporting clinical evidence. To assess whether active acupuncture, either alone or combined with clomiphene, increases the likelihood of live births among women with polycystic ovary syndrome. A double-blind (clomiphene vs placebo), single-blind (active v...

Background Traditional Chinese medicine (TCM) has a long history in the treatment of psoriasis vulgaris. We aimed to evaluate the clinical efficacy and safety of Chinese herbal Pulian ointment in treating psoriasis vulgaris of blood-heat syndrome. MethodsA multicenter, randomized, double-blind, placebo-controlled trial was conducted. Participants w...

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of direct-acting antivirals (DAAs) in patients with chronic hepatitis C virus infection.

Background Previous studies showed that high dose of caffeine intake may induce some specific human reproductive system diseases, even lead to infertility. Objectives In consideration of the high consumption of caffeine according to the latest population-based survey, this review is aimed to systematically review the evidence from all controlled cl...

Object: Traditional Chinese medicine (TCM) has been taught widely in the both Eastern and Western world countries. This study compared the origin, student source, duration, and curriculum design of TCM higher education programs in China and five Western countries. Method: We searched the Internet and the China National Knowledge Infrastructure (CNK...

Objective: To assess the effectiveness and safety of acupoint injection for the treatment of asthma. Methods: Six electronic databases were searched for randomized controlled trials (RCTs) of acupoint injection for asthma. Two authors extracted data and assessed methodological quality independently using the Cochrane Collaboration Risk of Bias tool...

Objectives: Homeopathy is a popular treatment modality among patient, however there is sparse research about adverse effects of homeopathy. A concept unique for homeopathy, is homeopathic aggravation that is understood as a transient worsening of the patients' symptoms before an expected improvement occurs. From a risk perspective it is vital that...

Introduction: There is a need for a structured approach to defining good practice of herbal medicines. This will enable a more targeted and efficient researching of individual herbs and herbal combinations. We explore the Five Phase model as a means of defining good practice of Chinese herbal medicines (CHM) which can be applied during clinical res...

Background: As a traditional treatment method, cupping therapy is widely used in Asian countries. This overview of systematic reviews (SRs) investigated the effectiveness and safety of cupping therapy through an evidence-based approach. Methods: SRs that assessed the effectiveness of cupping therapy for any type of disease were searched through 6 e...

The impact of transfusing fresher versus older red blood cells on patient-important outcomes remains controversial. Two recently published large trials have provided new evidence. We summarized results of randomized trials evaluating the impact of the age of transfused red blood cells. We searched MEDLINE, EMBASE, CINAHL, the Cochrane Database for...

Background: Summer acupoint herbal patching (SAHP) has been widely used in China for thousands of years. This bibliometric analysis aims to provide a comprehensive review of the characteristics of clinical studies on SAHP for any condition. Methods: We included clinical studies such as randomized clinical trials (RCTs), controlled clinical studi...

Ginkgo biloba is a natural medicine used for cognitive impairment and Alzheimer's disease. We conducted this review to evaluate the effectiveness and safety of Ginkgo biloba for mild cognitive impairment and Alzheimer's disease. We searched for randomized clinical trials of Ginkgo biloba for mild cognitive impairment and Alzheimer's disease in PubM...

This guideline aims to provide a methodological guidance for clinical studies in TCM and integrativemedicine in terms of study design, execution, and reporting. The commonly used methods includingexperimental and observational methods were introduced in this guideline such as randomized clinicaltrials, cohort study, case-control study, case series,...

There is no curative treatment for Alzheimer's disease (AD). Ginseng is widely used in the treatment of AD in Asian countries. To evaluate the effectiveness and safety of ginseng for AD. We searched six main databases for randomized clinical trials (RCTs) on ginseng for AD from their inception to December 2014. The Cochrane risk of bias tool was us...

OBJECTIVE: To explore consensus among Traditional Chinese Medicine (TCM)/ integrative medicine (IM) journal executive editors in China regarding: (a) Their perceptions about the differences between papers published in Chinese/English journals; (b) the key elements required for publishing a good quality paper; (c) how editors manage and decide on th...

Background: Acute urinary tract infection (UTI) is a common bacterial infection that affects 40% to 50% of women. Between 20% and 30% of women who have had a UTI will experience a recurrence, and around 25% will develop ongoing recurrent episodes with implications for individual well-being and healthcare costs. Prophylactic antibiotics can prevent...

ABSTRACT Background: Evidence-based medicine promotes and relies on the use of evidence in developing clinical practice guidelines (CPGs). The Chinese healthcare system includes both traditional Chinese medicine (TCM) and Western medicine, which are expected to be equally reflected in Chinese CPGs. Objective: To evaluate the inclusion of TCM-relate...

Objective. The aim of this systematic review is to evaluate effect of Chinese medicine combined with conventional therapy on blood pressure variability (BPV) in hypertension patients. Methods. All randomized clinical trials (RCTs) comparing Chinese medicine with no intervention or placebo on the basis of conventional therapy were included. Data ext...

Background: Persons with diabetes are at high risk of developing diabetic kidney disease (DKD), which is associated with high morbidity and mortality. Current drug therapies for DKD, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), are not entirely satisfactory. This study aimed to evaluate the add...

Background: Acupoint herbal patching (AHP) alone or as an adjuvant therapy with conventional treatment (CT) has been widely used for prevention and treatment of chronic obstructive pulmonary disease (COPD). However, current clinical evidence from a systematic review of RCTs is lacking.

Background Melasma is a common facial skin disorder seen in women. Manual acupuncture (MA) is widely used alone or in combination with conventional treatments for melasma in China. Objectives To assess the effectiveness and safety of MA for melasma, and explore the range of treatments applied. Methods Six databases were searched systematically for...