Jesus Simal-GandaraUniversity of Vigo | UVIGO · Department of Analytical and Food Chemistry
Jesus Simal-Gandara
Highly-Cited Researcher
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1,033
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Introduction
Jesus Simal-Gandara, Professor in Nutrition and Food Science at the Faculty of Food Science and Technology, University of Vigo (Spain)
He was 1st Spanish Award of Completion of Pharmacy and PhD Prize at the Faculty of Pharmacy, University of Santiago de Compostela (Spain). He also was Associate Professor in 1991 at the University of Vigo, where he is Full Professor since 1999. He now leads a research group of excellence at NW Spain, in addition to CIA3 (Environmental, Agricultural and Food Research Center) formed by 10 research groups from different fields (botany, plant physiology, soil science and agricultural chemistry, biochemistry and molecular biology, nutrition and food science, biotechnology, food technology, food rheology, chemical engineering, and colloidal chemistry), and also is the Head of the Department of Analytical Chemistry and Food Science at the University of Vigo.
He performed research stays at the Université de Paris-Sud (Paris, France), University of Delaware (Newark, USA), Fraunhofer-Institut für Lebensmitteltechnologie und Verpackung (Munich, Germany), Central Science Laboratory (Norwich and York, UK), TNO-Voeding (Zeist, Netherlands), Packaging Industries Research Association (Leatherhead, UK) and The Swedish Institute for Food and Biotechnology (Gothenburg, Sweden). He is editor of 4 national books. He published book chapters in 10 national and 14 international books. He directed 15 doctoral theses and participated in lots of competitive research projects, of which he was principal investigator at 20. He has numerous publications in international journals (http://scholar.google.es/citations?user=rmeHFXIAAAAJ&hl=es&oi=ao).
His research group is specialized in chromatographic separations (GC-MS and LC-MS) and molecular biology and proteomics. He investigates the distribution of agricultural and environmental organic chemical contaminants in the food production chain, and how improving the sensory and functional quality of food, with an eye on the food chain globally, integrating environment, agriculture and food with nutrition and public health issues. His focus today is on the study of persistent organic pollutants (POPs) from the point of view of public health (epidemiology, toxicity of mixtures, metabolites ...), and on the study of secondary metabolites in plant foods, exploring the molecular mechanisms that explain their activity.
Additional affiliations
November 1991 - present
Education
September 1988 - July 1991
Publications
Publications (1,033)
Resistance to apoptosis stands as a roadblock to the successful pharmacological execution of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an understanding of the mechanisms of apoptosis resistance are crucial to unveil new drug targets. At this juncture, researchers are heading towards natural sources in par...
The agri-food industry creates a vast amount of waste each year. This is not just a problem for waste management, in terms of finding space to store waste and preventing escape of harmful waste into the environment; it also represents a loss of resources: the chemicals and energy which have gone into the production of this waste. If current waste s...
Dietary flavonoids are abundant in natural plants and possess multiple pharmacological and nutritional activities. In this study, apigenin, luteolin, and baicalein were chosen to evaluate their anti-diabetic effect in high-glucose and dexamethasone induced insulin-resistant (IR) HepG2 cells. All flavonoids improves the glucose consumption and glyco...
Phytochemical-rich antioxidant extracts were obtained from Ascophyllum nodosum (AN) using microwave-assisted extraction (MAE). Critical extraction factors such as time, pressure, and ethanol concentration were
optimized by response surface methodology with a circumscribed central composite design. Under the optimal
MAE conditions (3 min, 10.4 bar,...
Cancer is a leading cause of mortality worldwide, and conventional cancer therapies such as chemotherapy and radiotherapy often result in undesirable and adverse effects. Natural products have emerged as a promising alternative for cancer treatment, with comparatively fewer side effects reported. Opuntia ficus-indica (L.) Mill., a member of the Cac...
Citrus, a genus of flowering plants in the Rutaceae family, holds substantial market importance as a crop worldwide. After prolonged periods of breeding and extensive hybridization, numerous species have emerged, each possessing a unique metabolism that produces a diverse array of secondary metabolites. It is important to note that phenolic compoun...
ABSTRACT: In this study, the removal of Crocein Orange G dye (COG) from aqueous solution was investigated using an
innovative green catalyst to overcome problems with chemical techniques. Clay bentonite El Hamma (HB)-supported nanoscale
zero-valent iron (NZVI) was used as a heterogeneous Fenton-like catalyst for the oxidation of harmful COG. Palm w...
To date, enumerable fungi have been reported to participate in the biodegradation of several notorious plastic materials following their isolation from soil of plastic-dumping sites, marine water, waste of mulch films, landfills, plant parts and gut of wax moth. The general mechanism begins with formation of hydrophobin and biofilm proceding to sec...
Citation: Chamorro, F.; Garcia-Oliveira, P.; Seyyedi-Mansour, S.; Echave, J.; Pereira, A.G.; Otero, P.; Simal-Gandara, J.; Prieto, M.A.; Cassani, L.; Fraga-Corral, M. Pectin Recovery Based on the Exploitation of Kiwi By-Products and the Application of Green Extraction Techniques. Eng. Proc. 2023, 48, 60. Abstract: The Actinidia genus comprises 54 s...
A R T I C L E I N F O Keywords: ZnO NPs Sol gel method XRD UV RAMAN analysis Ascochytafabae and antifungal activity A B S T R A C T The current work focuses on analysing the structural, optical, and anti-fungal efficacy of ZnO nanoparticles using well diffusion agar methods and minimum inhibitory concentration (MIC). ZnO nanoparticles were created...
The income and residue production from agriculture has a strong impact in Spain. A circular economy and a bioeconomy are two alternative sustainable models that include the revalorization of agri-food by-products to recover healthy biomolecules. However, most crops are conventional, implying the use of pesticides. Hence, the reutilization of agri-f...
In this study, an efficient, sensitive, and convenient magnetic solid-phase extraction method combined with ultra-high performance liquid chromatography-tandem mass spectrometry (MSPE-UHPLC-MS/MS) was developed for the simultaneous determination of 19 succinate dehydrogenase inhibitor fungicide residues in six different food matrices The synthesize...
Cognitive disorders, including dementia, Parkinson's and Alzheimer's disease, pose significant public health issues. Preventing/delaying their onset is essential as effective medical treatments are unavailable. Nuts contain bioactive compounds, including fatty acids, macronutrients such as proteins and dietary fibers, micronutrients, and polyphenol...
Al buscar los recursos turísticos de Dumbría, aparece esta curiosa lista, que podemos consultar al clicar sobre la imagen… Y, al observar que no menciona el Dolmen de Regoelle, por la proximidad a este lugar de Dumbría, aunque, en realidad pertenece al Concello de Vimianzo donde se cita como DOLMEN PEDRA DA ARCA (https://www.turismo.gal/recurso/-/d...
The Camellia genus (Theaceae) comprises more than 200 species, including the most famous Camellia sinensis (L.) Kuntze, Camellia oleifera Abel, and Camellia japonica (L.). The commercial interest in these plants linked to their seed fatty acid content increased in the last decades due to their quality and health-enhancing properties, which signific...
In recent decades, plants have strengthened their relevance as sources of molecules potentially beneficial for health. This underpinning effect also arises from the extensive research that has been conducted on plants that are typically undervalued, besides being scarcely used. This is the case with Camellia japonica in Galicia (NW Spain), where, d...
Fucoxanthin (Fx) has been proven to exert numerous biological properties, which makes it an interesting molecule with diverse industrial applications. In this study, the kinetic behavior of Fx was studied to optimize three variables: time (t-3 min to 7 days), temperature (T-5 to 85 °C), and concentration of ethanol in water (S-50 to 100%, v/v), in...
Patulin (PAT) is one of the most common mycotoxins produced by Penicillium and Aspergillus species and are often associated with fruits and fruit by-products, mostly apple derivatives, although it has been detected in infant food and cereals. This toxin has shown a mutagenic and carcinogenic effect. Thus, the development of rapid and accurate metho...
![Fig. 2. Phytochemicals targeting apoptotic pathways in cancer cells [125].](profile/Jesus-Simal-Gandara/publication/372149586/figure/fig1/AS:11431281174984153@1689456226543/Phytochemicals-targeting-apoptotic-pathways-in-cancer-cells-125_Q320.jpg)
Pomegranate, scientifically known as Punica granatum, has been a traditional medicinal remedy since ancient times. Research findings have shown that using pomegranate extracts can positively affect a variety of signaling pathways, including those involved in angiogenesis, inflammation, hyperproliferation, cellular transformation, the beginning stag...
Nowadays, coffee (Coffea Arabica L.) is among the most significant agricultural products of the world and drinking coffee has become one of the most popular habits in the world. The main contamination of stored coffee beans is related with the mycotoxin produced by the toxigenic fungi belonging the genus Aspergillus. Fungal infection followed by my...
In the present study bioactive methanolic extract along with chloroform and hexane extracts obtained from shade dried leaves of the Himalayan aromatic medicinal plant Nepeta leucophylla Benth. Were screened for the presence of triterpenoids, especially oleanolic acid (OA). Total three compounds oleanolic acid, squalene and linoleic methyl ester wer...
Macroalgae and microalgae are two sources of natural ingredients that are of interest for industrial sectors because of their multiple potential applications. Algal extracts are known to be rich in valuable compounds such as fatty acids, minerals, and secondary metabolites, among others. Bioactivities disclosed for these biocompounds include their...
Screening suitable allelopathic crops and crop genotypes that are competitive with weeds can be a sustainable weed control strategy to reduce the massive use of herbicides. In this study, three accessions of common buckwheat Fagopyrum esculentum Moench. (Gema, Kora, and Eva) and one of Tartary buckwheat Fagopyrum tataricum Gaertn. (PI481671) were s...
In this study, the clay was interwoven with cellulose to change its structure. The product clay/cellulose was used to assess the efficacy of the methylene blue (MB) dye removal from aqueous solutions (CC25). The response surface methodology and Box-Behnken design were used to optimize the influence of crucial parameters (cellulose load, adsorbent d...
Ochradenus baccatus Delile (Resedaceae) is a desert plant with edible fruits native to the Middle East. Few investigators have reported antibacterial, antiparasitic and anti-cancer activities of the plant. Herein we evaluate the cytotoxic activity of O. baccatus using four cell lines and a zebrafish embryo model. Additionally, liquid chromatography...
Currently, the incidence of metabolic disorders is increasing, setting a challenge to global health. With major advancement in the diagnostic tools and clinical procedures, much has been known in the etiology of metabolic disorders and their corresponding pathophysiologies. In addition, the use of in vitro and in vivo experimental models prior to c...
Special purple-colored leaf tea products rich in γ-aminobutyric acid (GABA) have recently gained popularity. Although anaerobic treatment could effectively increase the GABA content in tea products, it also imparted an unknown unpleasant aroma. This study aimed to elucidate the dynamic effects of anaerobic treatment on volatile components during th...
miRNAs are emerging as a novel proto-oncogene or tumor suppressor in the initiation and progression of cancer. Several plants naturally contain asparanin A (AA), which has potent anticancer properties. Previously, we discovered that AA exposure increased the expression of miR-6236-p5_4 and caused cytotoxicity in endometrial carcinoma (EC) Ishikawa...
La presencia de un Rollo en esta ciudad, se intuye por la toponimia, CALLE EL ROLLO, como podemos comprobar en la siguiente imagen de Google Maps-Street View de 2018. (clicar sobre la imagen) Además, el aspecto del crucero, situado delante de la "Estatua, en homenaje al Peregrino", en cuyo arranque del fuste circular, apoyado sobre un dado cuadrang...
En nuestro viaje a Gijón, antes de entrar a Asturias, desde Santiago, hicimos un interesante recorrido que traemos en esta reseña porque, además, encontramos unas interesantísimas imágenes atribuidas a Ribadeo ("Ribadeo, 1ere-ville-de-galice-sur-le-camino-del-norte-galicia-espana") https://ber-dranreb04.overblog.com/2018/03/eglise-de-ribadeo-1ere-v...
Al localizar esta parada de las Atarazanas (antiguos Astilleros Reales) en Google Maps, todavía
encontramos al río Daule, en la imagen dos veces mal indicado…, pues, como ya hemos
publicado, los ríos Daule y Babahayo, desde LA PUNTILLA, en Samborondón, unen sus aguas
para formar el río GUAYAS, que verterá sus aguas en el Golfo de Guayaquil en el Oc...
Al reseñar la desaparecida Puerta de Margarita de las antiguas murallas urbanas de Burgos, el
Ayuntamiento de Burgos, ha colocado una Placa para perpetuar su recuerdo, en la esquina de
la Plaza Alonso Martínez, se puede ver un lienzo de muralla con numerosas saeteras en buen
estado,
como podemos comprobar en la foto realizada en estos primeros días...
En el libro de Isidro Gil, 1913, https://www.iberlibro.com/buscar-libro/titulo/burgosprovincia/
autor/gil-isidro/ , del que representamos estas dos páginas iniciales
y otra tercera, la nº 100, esta vez descargada del Archivo Municipal de Burgos.También
llamada “De Doña Lambra o de la Judería”, por su proximidad a este torreón
https://twitter.com/Ar...
Al recorrer las calles de Santiago de Compostela suele sorprendernos los escudos, inscripciones y otras marcas menores que son
consideradas como “Marcas de Propiedad” que han sido objeto de diferentes publicaciones, sobre papel y/o digitales [1,2,3,4…],
atribuidas a una decena de Instituciones (Cabildo, Monasterios o Conventos, Ayuntamiento, Hospit...
Melons (Cucumis melo L.) are highly popular due to its delicate and delightful flavor in the worldwide. However, the flavor of the melon juice was easily affected by thermal treatments and unpleasant cooking smell during production process. Sugarcane (Saccharum officinarum) juice is a proven nutritious beverage with high levels of antioxidants, pol...
Esta vez queremos establecer la posición correcta del Mirador Bellavista en Cerro Paraíso de Guayaquil, pues, como puede verse en la imagen de Google Maps, una está situada bastante abajo, adonde llega el autobús turístico (1) y la segunda marca, en la zona de aparcamiento, de coches, algo más arriba, con bastante subida, a la que no todas las pers...
Estas ruinas están dentro de una ruta de senderismo que iniciamos en Novais, hasta donde se
puede llegar en coche desde Portomouro km 28,35, dirección “Sartego de Pedra do Home”,
Trazo/Ordes, hasta Ruinas de Capilla prerrománica(?), (unos 3 km, 1,3 km por la DP-5903 y
1,7Km hasta el final del camino asfaltado en Novais).
Desde aquí hemos caminad...
Al hacer una reseña sobre la Aerovia en Guayaquil, Ecuador, hemos situado en Google Maps y
estimado su recorrido sobre el río Guayas, y nos hemos encontrado con el nombre de rio
Daule, que entendemos no es correcto.
Por lo que adjuntamos documentación para corregir este error en esta capa de 500m, en
Google Maps, veamos:
El río Guayas, resultado de...
Instroducción En un reciente viaje a Santiago de Guayaquil, Ecuador, hemos utilizado para nuestros desplazamientos esta económica, rápida, sencilla, bonita, ágil, mirador móvil… forma de desplazarnos desde nuestro Hotel, a unos 250 m de la Estación Parque del Centenario (E01), en la avenida 9 de octubre a la Estación E04, "Cuatro Mosqueteros" en el...
Algunos comentarios para su vistita: En Google Maps, aparecen dos marcadores: uno, "JARDIM BOTÁNICO" frente a la entrada 4 PORTÃO DE BROTERO y el otro, más al Oeste, "Jardin Botanico de la Universidad de Coimbra Jardin tranquilo con plantes y fuentes" El Jardín, tiene 6 puertas de las cuales la 2, no es pública, como se expone en las entradas:
La ciudad de Coímbra, la AEMINUM ROMANA, ha tenido numerosos recintos como puede comprobarse en la obra de Isabel de Moura Anjinho-2016, Volumen 1,
Lignocellulosic biomass is a powerful material for producing sustainable biofuels because it converts into second-generation clean energy capable of coping with the depletion of fossil reserves and rising energy demands. However, pretreatment is required in the conversion process to overcome the recalcitrance of the lignocellulosic biomass, acceler...
Supercritical fluid extraction (SFE) is a non-conventional extraction technique that can be 15 used in the food industry because it can recover both polar and non-polar compounds. This 16 technique is carried out above the critical point of the extraction solvent, allowing for the control 17 and manipulation of different properties such as diffusiv...
Olive family (Oleaceae) contains several species among which Olea europaea L. is mostly used for production of olive oils. Various parts of olive tree are rich source of diverse bioactive compounds such as Apigenin, elenolic acid, Hydroxytyrosol, Ligstroside, Oleoside, Oleuropein, Oleuropein aglycone, Tyrosol, etc. Among these, oleuropein, a secoir...
Hydroxymethylfurfural (HMF) is a naturally occurring compound that arises because of the thermal processing and storage of honey. The Codex Alimentarius Commission has established a threshold of 40 ppm as the upper limit for HMF content in honey. This research aimed to inves-tigate the impact of varying heating temperatures (55, 65, and 75°C) and h...
Plants are producers of many secondary metabolites with biological activities like alkaloids, terpenes, lignans, tannins, and phenolic compounds which can be used in the development of pharmaceutical drugs. Because of the complex chemical structure, these compounds are difficult to synthesize at an industrial level. Thus, using appropriate extracti...
Cannabidiol (CBD), a medically active component of hemp, is a popular ingredient in healthcare and personal-care products. The increasing demand for CBD and the legalization of hemp growth may promote chronic exposure of non-target organisms to CBD. In this study, the reproductive toxicity of CBD was investigated on adult zebrafish. With CBD treatm...
Hydroxymethylfurfural (HMF) is a naturally occurring compound that arises because of the thermal processing and storage of honey. The Codex Alimentarius Commission has established a threshold of 40 ppm as the upper limit for HMF content in honey. This research aimed to investigate the impact of varying heating temperatures (55, 65, and 75°C) and he...
The antimicrobial activity of plants, algae and derived extracts has been a subject of interest for the scientific community. Algae extracts have demonstrated their potential as a source of natural antimicrobial agents. Because of their antibacterial capacity and low toxicity, algal extracts have been studied as natural preservatives in food and co...
Camellia japonica is an underexplored medicinal plant with associated bioactivities [1]. Innovative approaches are proposed in regard to the large-scale application of C. japonica, being one of the main lines the extraction of phenolic compounds [2]. The optimum conditions for the extraction of phenolic compounds form the flowers of C. japonica var...
In this work, we studied the potential of supercritical fluid CO2 technology to extract almond wastes and obtain a fiber product rich in minerals and phenolics without the use of extraction co-solvent. The analysis of phenolics in the resulting extracted product was performed by liquid chromatography tandem mass spectrometry (LC-MS/MS) and showed v...
The present study strengthens the food preservative potential of Chamaerops humilis extracts viz. hexane extract, chloroform extract, ethanol extract, chloroform extract, and methanol extract based on their antifungal, antiafla-toxin, and antioxidant efficacy. The isolation of molds from peanuts were carried out by the suspension-dilution technique...
Small berries have become an attractive topic of research due to their high content in phenolic compounds and reported antioxidant activity. However, there are currently few reports on the deep characterization of their polyphenol composition. Five kinds of berries (raspberry, blackberry, blueberry, mulberry and black chokeberry) were studied to co...
Edible mushrooms are popular functional foods attributed to their rich nutritional bioactive constituent profile influencing cardiovascular function. Edible mushrooms are omnipresent in various prescribed Dietary Approaches to Stop Hypertension,
Mediterranean diet, and fortified meal plans as they are rich in amino acids, dietary fiber, proteins, s...
Polyhydroxy flavonols readily degraded during thermal processing. In this study, the UPLC-Q-tof-MS/MS was applied to explore the stability of dietary polyhydroxy flavonols, myricetin, kaempferol, galangin, fisetin, myricitrin, quercitrin and rutin, in boiling water. The decomposition of flavonols was mainly caused by the heterocyclic ring C opening...
Despite advancements in food preservation ways, the nature of preservatives remains one of the real problems that must be taken into account for the preservation of consumer health. To cope with the problems of contamination and oxidation of foodstuffs, the chemistry development has favored the appearance and application of new chemical substances...
Grape is the third most produced fruit in the world, owing to its taste and its use as raw material for winemaking. Due to this fact, large volumes of waste biomass are generated as a result of grape juice and wine production, mainly grape seeds (GS) and peels. In recent decades, scientific research has highlighted the high content of polyphenols i...
The number of preclinical and clinical studies evaluating natural products-based management of dementia has gradually increased, with an exponential rise in 2020 and 2021. Keeping this in mind, we examined current trends from 2016 to 2021 in order to assess the growth potential of natural products in the treatment of dementia. Publicly available li...
Configuración del móvil con WI-FI, y proxy
Macroalgae are an extensive resource for the obtention of bioactive compounds, mainly phenolic compounds, phlorotannins, and pigments. Fucoxanthin (Fx) is the most abundant pigment present in brown algae and has shown several useful bioactivities that can be used to fortify products in the food and cosmetic industries. Nevertheless, to date, there...