Jesus Simal-Gandara

University of Vigo | UVIGO · Department of Analytical and Food Chemistry

Marine polysaccharides have gained attention for their abundance, low cost, and beneficial properties, making them ideal for smart delivery systems in nanotechnology. Fucoidan (FU), a polysaccharide from brown algae, offers significant biological activities such as anticancer, anticoagulant, antiviral, antioxidant, and anti-inflammatory effects. Du...

The present study aimed to optimize the extraction conditions (time, temperature, and ethanol concentration) of pressurized-liquid and microwave-assisted extraction (PLE and MAE, respectively) to maximize the recovery of phenolic compounds from Arnica montana flowers. To this aim, response surface methodology (RSM) with an experimental design was a...

Carica papaya (Family Caricaceae) is endowed with a myriad of biological activities as gastroprotective, antidiabetic, antimalarial, antiviral, and anti-inflammatory agent. We performed for the first time an extensive comparative metabolite profiling of different plant organs considering both male and female leaves, seeds, and fruits of different m...

In recent years, consumers have been increasingly interested in natural, healthier, functional foods, with a focus on sea-based products such as algae. Bifurcaria bifurcata (BB) is a macroalga that belongs to the Phaeophyceae class. These brown algae are recognized as the source of bioactive molecules of great interest to the pharmaceutical and nut...

Marine biodiversity has acquired greater significance across the world, and it is increasingly being utilized as a source of natural products. Considering that marine resources comprise a wide range of intriguing antioxidant molecules and other appealing biotechnological compounds, they are drawing the interest of industry sectors such as foods, ph...

Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology, and future prospe...

This study aimed to optimize phenolic compound extraction from Arnica montana (AM) L. flowers, comparing heat- and ultrasound-assisted extraction (HAE and UAE) through a multivariate approach. Critical parameters, including time, temperature or ultrasonic power, and ethanol concentration, were evaluated through a circumscribed central composite des...

Sargassum muticum (SM) poses a serious environmental issue since it is a fast-expanding invasive species occupying key areas of the European shoreline, disrupting the autochthonous algae species, and disturbing the ecosystem. This problem has concerned the general population and the scientific community. Nevertheless, as macroalgae are recognized a...

Citation: Pereira, A.G.; Fraga-Corral, M.; Silva, A.; Barroso, M.F.; Grosso, C.; Carpena, M.; Garcia-Perez, P.; Perez-Gregorio, R.; Cassani, L.; Simal-Gandara, J.; et al. Unraveling the Bioactive Potential of Camellia.es (A.G.P.); mprieto@uvigo.es (M.A.P.) † These authors contributed equally to this work. Abstract: In recent years, the search for n...

Algae are considered a valuable and varied source of natural compounds and ingredients which presence is highly demanded in the market by consumers. Algae have attracted the attention of industrial sectors for their cost-effective and sustainable production. They are photosynthetic organisms capable of sequestering huge amounts of CO2 from the atmo...

Pomegranate peel is the by-product of pomegranate processing, which contains a lot of triterpene compounds. In this study, the total triterpenes of pomegranate peel (TPP) were extracted using an ultrasonic-assisted ethanol extraction method under optimal conditions, purified using D-101 macroporous resin to obtain a purity of 75.28%. The triterpene...

Chronic inflammation-induced diseases (CID) are the dominant cause of death worldwide, contributing to over half of all global deaths. Sulforaphane (SFN) derived from cruciferous vegetables has been extensively studied for its multiple functional benefits in alleviating CID. This work comprehensively reviewed the biosynthesis, metabolism, bioavaila...

Recently, nanoscale biotechnology has emerged as an essential field of contemporary science and a new era in the study of materials. It draws the attention of many scientists from all over the world due to its versatility in various fields. Many physical, chemical, and biological processes are used to create biomaterials. Among the materials of int...

This study investigated the potential use of fish paste from two pelagic species (Cetengraulis mysticetus or carduma in Colombia and Opisthonema sp. or plumuda in Colombia), either separately or combined, as a substitute for external fat sources in a Leberkäse product. Three stages were analyzed, evaluating biometric proportions, body performance,...

A Potato (Solanum tuberosum L.) is a major staple food consumed worldwide. Potato peel is an important constituent that is generally discarded and considered agricultural waste before processing or cooking. The present investigation is an attempt to utilize different contents of potato peels (PP) with potato flesh (PF) of processing cultivar (Kufri...

Vitamin D deficiency is currently a significant public health issue closely linked to numerous diseases, such as breast cancer. This study aims to determine the estimated optimal serum levels of vitamin D to have a protective effect against breast cancer, in addition to exploring the biological mechanisms and risk factors involved. A literature sea...

This studỳs aim was to evaluate the quality of water for human consumption in a rural area of Ecuador. For this purpose, two water quality indexes were used: the Water Quality Index (WQI) and the Simplified Water Quality Index (SWQI). Sampling campaigns were carried out during the years 2018 and 2019, and 18 parameters were analyzed, including pH,...

Al revisar los Moinhos de Maré en el Estuario del Tejo, Molinos de Marea en el Estuario del Tajo en español, entre los 18 que tenemos localizados en el mapa que estamos creando en Google Maps, nos hemos encontrado con esta zona de Alburrica de Barreiro, en la que, además del Moinho de Maré Pequeno, convertido en Centro de interpretación, y que pued...

En la Reserva Natural do Estuario do Sado, al localizar en Google Maps los “Moinho de Maré”, aparece, a 5 km en vista satélite, dos Moinhos de Maré, el de Mourisca al norte de la Foz o Estuario del río Sado, que por cierto no aparece en este mapa…? Moinho de Maré da Mourisca, rio Sado vista en Google Maps, 3D, (3m), mostrando al fondo la ciudad de...

Over the years, foodborne pathogens have caused countess health problems and massive financial losses. Therefore, an essential goal for the food industry is to prevent food contamination and the related foodborne illnesses as microbial contamination of food items during their acquiring and distribution processes is still a hygienic issue. Moreover,...

Resistance to apoptosis stands as a roadblock to the successful pharmacological execution of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an understanding of the mechanisms of apoptosis resistance are crucial to unveil new drug targets. At this juncture, researchers are heading towards natural sources in par...

Macroalgae are sustainable and natural sources of proteins, their content may reach values up to 40% of their total weight. Besides, they are especially attractive for their rich and abundant amount of essential amino acids with proportions of 30%–40% which are comparable to other terrestrial organisms, such as legumes. Hence, protein from macroalg...

The agri-food industry creates a vast amount of waste each year. This is not just a problem for waste management, in terms of finding space to store waste and preventing escape of harmful waste into the environment; it also represents a loss of resources: the chemicals and energy which have gone into the production of this waste. If current waste s...

Dietary flavonoids are abundant in natural plants and possess multiple pharmacological and nutritional activities. In this study, apigenin, luteolin, and baicalein were chosen to evaluate their anti-diabetic effect in high-glucose and dexamethasone induced insulin-resistant (IR) HepG2 cells. All flavonoids improves the glucose consumption and glyco...

Phytochemical-rich antioxidant extracts were obtained from Ascophyllum nodosum (AN) using microwave-assisted extraction (MAE). Critical extraction factors such as time, pressure, and ethanol concentration were optimized by response surface methodology with a circumscribed central composite design. Under the optimal MAE conditions (3 min, 10.4 bar,...

Cancer is a leading cause of mortality worldwide, and conventional cancer therapies such as chemotherapy and radiotherapy often result in undesirable and adverse effects. Natural products have emerged as a promising alternative for cancer treatment, with comparatively fewer side effects reported. Opuntia ficus-indica (L.) Mill., a member of the Cac...

Citrus, a genus of flowering plants in the Rutaceae family, holds substantial market importance as a crop worldwide. After prolonged periods of breeding and extensive hybridization, numerous species have emerged, each possessing a unique metabolism that produces a diverse array of secondary metabolites. It is important to note that phenolic compoun...

Food spoilage concerns from ethical, social, economic, and environmental points of view because of its direct link to food insecurity. At every stage of the value chain, food products are subject to spoilage due to the loss of freshness resulting from contamination caused by flaws in the traceability or adulteration events. The existing quality con...

ABSTRACT: In this study, the removal of Crocein Orange G dye (COG) from aqueous solution was investigated using an innovative green catalyst to overcome problems with chemical techniques. Clay bentonite El Hamma (HB)-supported nanoscale zero-valent iron (NZVI) was used as a heterogeneous Fenton-like catalyst for the oxidation of harmful COG. Palm w...

To date, enumerable fungi have been reported to participate in the biodegradation of several notorious plastic materials following their isolation from soil of plastic-dumping sites, marine water, waste of mulch films, landfills, plant parts and gut of wax moth. The general mechanism begins with formation of hydrophobin and biofilm proceding to sec...

Citation: Chamorro, F.; Garcia-Oliveira, P.; Seyyedi-Mansour, S.; Echave, J.; Pereira, A.G.; Otero, P.; Simal-Gandara, J.; Prieto, M.A.; Cassani, L.; Fraga-Corral, M. Pectin Recovery Based on the Exploitation of Kiwi By-Products and the Application of Green Extraction Techniques. Eng. Proc. 2023, 48, 60. Abstract: The Actinidia genus comprises 54 s...

A R T I C L E I N F O Keywords: ZnO NPs Sol gel method XRD UV RAMAN analysis Ascochytafabae and antifungal activity A B S T R A C T The current work focuses on analysing the structural, optical, and anti-fungal efficacy of ZnO nanoparticles using well diffusion agar methods and minimum inhibitory concentration (MIC). ZnO nanoparticles were created...

The income and residue production from agriculture has a strong impact in Spain. A circular economy and a bioeconomy are two alternative sustainable models that include the revalorization of agri-food by-products to recover healthy biomolecules. However, most crops are conventional, implying the use of pesticides. Hence, the reutilization of agri-f...

In this study, an efficient, sensitive, and convenient magnetic solid-phase extraction method combined with ultra-high performance liquid chromatography-tandem mass spectrometry (MSPE-UHPLC-MS/MS) was developed for the simultaneous determination of 19 succinate dehydrogenase inhibitor fungicide residues in six different food matrices The synthesize...

Cognitive disorders, including dementia, Parkinson's and Alzheimer's disease, pose significant public health issues. Preventing/delaying their onset is essential as effective medical treatments are unavailable. Nuts contain bioactive compounds, including fatty acids, macronutrients such as proteins and dietary fibers, micronutrients, and polyphenol...

Al buscar los recursos turísticos de Dumbría, aparece esta curiosa lista, que podemos consultar al clicar sobre la imagen… Y, al observar que no menciona el Dolmen de Regoelle, por la proximidad a este lugar de Dumbría, aunque, en realidad pertenece al Concello de Vimianzo donde se cita como DOLMEN PEDRA DA ARCA (https://www.turismo.gal/recurso/-/d...

The Camellia genus (Theaceae) comprises more than 200 species, including the most famous Camellia sinensis (L.) Kuntze, Camellia oleifera Abel, and Camellia japonica (L.). The commercial interest in these plants linked to their seed fatty acid content increased in the last decades due to their quality and health-enhancing properties, which signific...

In recent decades, plants have strengthened their relevance as sources of molecules potentially beneficial for health. This underpinning effect also arises from the extensive research that has been conducted on plants that are typically undervalued, besides being scarcely used. This is the case with Camellia japonica in Galicia (NW Spain), where, d...

Fucoxanthin (Fx) has been proven to exert numerous biological properties, which makes it an interesting molecule with diverse industrial applications. In this study, the kinetic behavior of Fx was studied to optimize three variables: time (t-3 min to 7 days), temperature (T-5 to 85 °C), and concentration of ethanol in water (S-50 to 100%, v/v), in...

Patulin (PAT) is one of the most common mycotoxins produced by Penicillium and Aspergillus species and are often associated with fruits and fruit by-products, mostly apple derivatives, although it has been detected in infant food and cereals. This toxin has shown a mutagenic and carcinogenic effect. Thus, the development of rapid and accurate metho...

Pomegranate, scientifically known as Punica granatum, has been a traditional medicinal remedy since ancient times. Research findings have shown that using pomegranate extracts can positively affect a variety of signaling pathways, including those involved in angiogenesis, inflammation, hyperproliferation, cellular transformation, the beginning stag...

Nowadays, coffee (Coffea Arabica L.) is among the most significant agricultural products of the world and drinking coffee has become one of the most popular habits in the world. The main contamination of stored coffee beans is related with the mycotoxin produced by the toxigenic fungi belonging the genus Aspergillus. Fungal infection followed by my...

In the present study bioactive methanolic extract along with chloroform and hexane extracts obtained from shade dried leaves of the Himalayan aromatic medicinal plant Nepeta leucophylla Benth. Were screened for the presence of triterpenoids, especially oleanolic acid (OA). Total three compounds oleanolic acid, squalene and linoleic methyl ester wer...

Macroalgae and microalgae are two sources of natural ingredients that are of interest for industrial sectors because of their multiple potential applications. Algal extracts are known to be rich in valuable compounds such as fatty acids, minerals, and secondary metabolites, among others. Bioactivities disclosed for these biocompounds include their...

Screening suitable allelopathic crops and crop genotypes that are competitive with weeds can be a sustainable weed control strategy to reduce the massive use of herbicides. In this study, three accessions of common buckwheat Fagopyrum esculentum Moench. (Gema, Kora, and Eva) and one of Tartary buckwheat Fagopyrum tataricum Gaertn. (PI481671) were s...

In this study, the clay was interwoven with cellulose to change its structure. The product clay/cellulose was used to assess the efficacy of the methylene blue (MB) dye removal from aqueous solutions (CC25). The response surface methodology and Box-Behnken design were used to optimize the influence of crucial parameters (cellulose load, adsorbent d...

Ochradenus baccatus Delile (Resedaceae) is a desert plant with edible fruits native to the Middle East. Few investigators have reported antibacterial, antiparasitic and anti-cancer activities of the plant. Herein we evaluate the cytotoxic activity of O. baccatus using four cell lines and a zebrafish embryo model. Additionally, liquid chromatography...

Currently, the incidence of metabolic disorders is increasing, setting a challenge to global health. With major advancement in the diagnostic tools and clinical procedures, much has been known in the etiology of metabolic disorders and their corresponding pathophysiologies. In addition, the use of in vitro and in vivo experimental models prior to c...

This study aims to biocontrol of Bacillus cereus by Lactobacillus plantarum in Kareish cheese and yogurts. The minimum inhibitory concentrations (MICs), antioxidant potentials, total flavonoids content (TFC) and total phenolic content (TPC) of L. plantarum were also estimated. Results showed that incidence of B. cereus in Kareish cheese and yogurt...