Jesús Armando Sánchez

• MD, MSc.
• Professor (Associate) at Pontifical Xavierian University

In Caucasians and Native Americans living at altitude, hemoglobin mass is increased in spite of erythropoietin concentrations ([Epo]) not markedly differing from sea level values. We hypothesized that a nocturnal decrease of arterial oxygen saturation (SaO2) causes a temporary rise of [Epo] not detected by morning measurements. SaO2 (continuous, fi...

La importancia de la Epo como hormona central en los procesos de ambientación a la altura es clara dado su efecto estimulante sobre la producción eritrocitaria. Su naturaleza hormonal ha llevado a que algunas investigaciones evalúen su circadianidad con reportes no contundentes e inclusive contradictorios al respecto. Objetivo: Analizar la circadia...

Erythropoietin Epo is the key hormone in the process of erythropoiesis and, therefore, essential for acclimation to altitude. Although circadian variation in Epo levels has been reported before, the results are often contradictory. Here, we tested the hypothesis that Epo levels follow a circadian variation and that such variation depends on gender...

The venoms of coral snakes (genus Micrurus) are known to induce a broad spectrum of pharmacological activities. While some studies have investigated their potential human effects, little is known about their mechanism of action in terms of the ecological diversity and evolutionary relationships among the group. In the current study we investigated...

This chapter focuses on the molecular and cellular properties of the lung, and the mechanisms involved in the respiratory control throughout three integrative models: The defense mechanisms of the airways. The lung response to mechanical stress. Regulatory components of the respiratory regulation.

Organic evolution has been essentially linked to oxygen (O2) since it was first introduced in the earth’s atmosphere by photosynthesis of early cyanobacteria species some 2.5 billion years ago. In the steady state (i.e., normoxia), most of the oxygen consumed by a cell is used by mitochondria in the generation of adenosine triphosphate (ATP) via ox...

En la práctica clínica un común efecto adverso del litio es la aparición de temblor en reposo. Actualmente no existe una explicación satisfactoria de este fenómeno, por lo que se dificulta su manejo. El objetivo del presente estudio fue determinar el efecto del litio sobre la excitabilidad de la unión neuromuscular en una preparación in vitro, con...

is diffi cult. This study evaluated the lithium’s effect on neuromuscular junction excitability using an in vitro preparation. In order to investigate a peripheral mechanism that could explain lithium induced tremor. The in vitro rat phrenic nerve-diaphragm preparation was exposed to increasing concentrations of Lithium (0,25-8 mmol/l). The prepara...

Disponible en: http://www.redalyc.org/articulo.oa?id=91012103.