Jesús Escanero

• University of Zaragoza

Plasma lipid changes during incremental exercise are not well known. The aim of this study was to investigate the relationship among fat oxidation rate, plasma lipids, and hormone concentrations in well-trained athletes. Twenty-six trained triathletes completed a graded cycle ergometer test to exhaustion increasing by 0.5 W·kg−1 every 10 minutes. F...

Background Different laboratory methods are used to quantify ferritin concentrations as a marker of iron status. A systematic review was undertaken to assess the accuracy and comparability of the most used methods for ferritin detection. Methods and findings National and regional databases were searched for prospective, retrospective, sectional, l...

Summary of studies reporting Bland-Altman (B-A) statistics: Mean and standard deviation of the regression intercept and slope between different detection techniques. (DOCX)

Characteristics of the studies included in meta-analysis. (DOCX)

PRISMA checklist ferritin methods. (DOC)

Review ferritin methods PROSPERO registration. (PDF)

Laboratory assessment data from a quality control program of the Spanish Society of Clinical Biochemistry and Molecular Pathology (2014). (DOCX)

Introducción: La aplicación de la teoría de los estilos de aprendizaje sirve para mejorar aquellos que tienen baja puntuación y capacitar a los estudiantes a aprender en las mejores condiciones en cualquier contexto. Para ello, la determinación de estilos por los distintos cuestionarios debe ser superponible. Por otro lado, la relación entre estilo...

Background: Blood hemoglobin (Hb) concentration within the reference interval does not exclude iron deficiency (ID): individuals with normal stores lose iron during a long period before their Hb falls below of the level that is defined as anemia. The process entails a decrease of storage iron, shown by serum ferritin below reference range, followe...

Background: Iron deficiency (ID) is the most common cause of anemia in fertile women and hemoglobin (Hb) within the reference interval does not exclude ID. The consequence of an imbalance between the iron requirements and supply is a reduction of red-cell Hb content, which causes hypochromic cells. The aim of this study was to assess the reliabili...

Introduction. About the style term there are different definitions and a lot of questionnaires to determine them; moreover, rankings are heterogeneous and meaning of different styles is not coincident. Subjects and methods. In order to clarify some points, this paper presents a new tool (CESEA) and compares the results obtained with those provided...

This study analyzes the relationship between hormonal changes induced by exercise and variations in trace elements associated with oxidative stress during incremental exercise. Nineteen well-trained endurance athletes performed a cycle ergometer test: after a warm-up of 10 min at 2.0 W kg(-1), workload increased by 0.5 W kg(-1) every 10 min until e...

Variants of the solute carrier SLC16A1 gene have been associated with alterations in MCT1 expression, due to a lactate (La-) transport deficiency across the cell membrane and a blood La- accumulation. The aim of the present study was to associate the allelic and genotypic frequencies of 1470T>A, 2917(1414) C>T and IVS3-17A>C variants relative to th...

This study analyzed the variation and relationship of several trace elements, metabolic substrates and stress hormones activated by exercise during incremental exercise. Seventeen well-trained endurance athletes performed a cycle ergometer test: after a warm-up of 10min at 2.0Wkg(-1), the workload was increased by 0.5Wkg(-1) every 10min until exhau...

This year (2014) we are celebrating the 80 th anniversary of Dr Maxwell Myer Wintrobe's pioneer works, one of the most important contributions in clinical laboratory and medicine. Red cell indices continue to provide an essential support to the diagnosis and classification of anaemia. The erythrocyte indices, such as mean cell volume, mean cell hem...

This year (2014) we are celebrating the 80 th anniversary of Dr Maxwell Myer Wintrobe's pioneer works, one of the most important contributions in clinical laboratory and medicine. Red cell indices continue to provide an essential support to the diagnosis and classification of anaemia. The erythrocyte indices, such as mean cell volume, mean cell hem...

Abstract To investigate the effects of sulphurous mineral water (SMW) after a hydroponic treatment on muscle damage, antioxidant activity and peripheral blood changes induced by submaximal exercise. Thirty well-trained male triathletes were supplemented with SMW or placebo: 3 weeks of placebo, 30 days of wash out and 3 weeks of SMW. After both peri...

Microcytic anemia is frequently due to iron deficiency (IDA) or thalassemia. Other causes are Anemia of chronic disease (rheuma-toid arthritis, Hodgkin lymphoma) and hereditary or acquired sideroblastic anemia or lead poisoning. Both diseases are endemic; represent a problem of public health particularly in the developing countries. The World Healt...

Microcytic anemia is frequently due to iron deficiency (IDA) or thalassemia. Other causes are Anemia of chronic disease (rheuma-toid arthritis, Hodgkin lymphoma) and hereditary or acquired sideroblastic anemia or lead poisoning. Both diseases are endemic; represent a problem of public health particularly in the developing countries. The World Healt...

The hemochromatosis term describes a group of diseases caused by excess iron in the body. Hemochromatosis is the inborn error of metabolism most frequent (80%) and is considered a potentially serious illness due to cell damage that occur in different organs such as liver, heart, joins, skin or pancreas because for much of the life can develop witho...

Introducción: El conocimiento metacognitivo que posee un individuo le permite sentirse más motivado y a medida que es más consciente de los mecanismos de autorregulación de los procesos que utiliza para el aprendizaje aprende mejor y más eficazmente. En este trabajo se analiza la relación existente entre los estilos de aprendizaje y el conocimiento...

Iron status is the result of the balance between the rate of erythropoiesis and the amount of the iron stores. Direct consequence of an imbalance between the erythroid marrow iron requirements and the actual supply is a reduction of red cell hemoglobin content, which causes hypochromic mature red cells and reticulocytes. The diagnosis of iron defic...

The percentage of hypochromic red cells (% Hypo-He) is now available on the Sysmex analyzer XE 5000 (Sysmex Corporation, Kobe, Japan). In this study the reliability of % Hypo-He in the assessment of iron status in the presence of inflammation is investigated. Ninety healthy subjects, 91 patients with iron deficiency anemia (IDA) previous to therapy...

The purpose of this study was to assess the effects of oral iron supplementation on hematological and iron metabolism in elite soccer players. Thirty-five members of the Real Zaragoza SAD soccer team took part in this study: group A (GA, n = 24; Spanish Premier League) took an oral iron supplement of 80 mg day(-1) for 3 weeks, and group B (GB, n = ...

We analyse magnesium levels in amniotic fluid to establish normal values for the 14th to 18th week of pregnancy and establish critical values that could be useful diagnostic and therapeutic guidelines for possible complications. Ninety-two samples of amniotic fluid obtained by amniocentesis as well as the corresponding serum samples of pregnant wom...

The purpose of this study was to assess the effect of exercise intensity during an incremental exercise test on plasma Mg concentration in well-trained euhydrated athletes. Twenty-seven well-trained endurance athletes carried out a cycloergometer test: after a warm-up of 10 min at 2.0 W·kg(-1), the workload increased by 0.5 W·kg(-1) every 10 min un...

Cell counter based formulas have been used in the differential diagnosis of microcytic anemia. The measurement of RBC subpopulations is now available on the Sysmex XE 5000 analyzer (Sysmex, Kobe, Japan). We describe the new formulas: % microcytic % hypochromic; and % microcytic - % hypochromic - - red cell distribution width (RDW), derived from the...

Cell counter-based formulas have been used in the differential diagnosis of microcytic anemia. The measurement of RBC subpopulations is now available on the Sysmex XE 5000 analyzer (Sysmex, Kobe, Japan). We describe the new formulas: % microcytic - % hypochromic; and % microcytic - % hypochromic - red cell distribution width (RDW), derived from the...

Red blood cells (RBCs) extended parameters or erythrocyte subsets are now reported by the new Sysmex XE 5000 analyzer. This study was aimed at establishing a characteristic analytical feature, including the new erythrocyte and reticulocyte parameters, in case of thalassemia trait and iron deficiency (IDA). Ninety healthy individuals, 136 β-thalasse...

The purpose of this study was to assess the effect of relative exercise intensity on various plasma trace elements in euhydrated endurance athletes. Twenty-seven well-trained endurance athletes performed a cycloergometer test: after a warm-up of 10 min at 2.0 W kg⁻¹, workload increased by 0.5 W kg⁻¹ every 10 min until exhaustion. Oxygen uptake, blo...

The aim of this study is to analyze the variation of the elements (Ca, Mg, Cu, Fe, Zn and Mn) in normal and pathological CSF and develop a classification basing on the increases in cells and proteins and taking into account these variations. A total of 173 cerebrospinal fluids were analyzed. Of these, 37 fulfilled the criteria of normality and, aft...

Reticulocyte hemoglobin content (CHr) and percentage of hypochromic cells (%Hypo) are restricted to the Siemens analysers. The aims of the study were to investigate the correlation of Red cells size factor (RSf) and low Hemoglobin density (LHD%), reported by Beckman-Coulter analysers, with CHr and %Hypo in the assessment of iron status in the pres...

The aim of this study was to characterize the learning styles of different groups of athletes grouped according to level of performance and sport. Seventy-one male athletes completed a questionnaire on learning styles at the beginning of the 2008-2009 training season. Learning styles were assessed using the Honey-Alonso Learning Styles Questionnair...

New erythrocyte parameters are reported by the Sysmex XE 5000 analyzer. This instrument measures the hemoglobin (Hb) content of individual red cells, calculates the percentage of hypochromic red cells (%Hypo He) and the percentage of hyperchromic red cells (%Hyper He) and quantifies the proportion of marginally sized erythrocytes (%Micro R and %Mac...

PURPOSE: To assess the effects of a sprint distance duathlon laboratory simulation on FAToxr and CHOoxr. METHODS: 8 national level duathletes performed two incremental laboratory tests until exhaustion on a cycle ergometer (Initial workload: 60 W, stages: 30 W·min-1) and on a treadmill (Initial workload: 5 km·h-1, stages: 1 km·h-1) respectively to...

Stricter regulations and controls for environmental lead have resulted in significantly lower frequency and reduced severity of chronic and acute lead intoxication. The aim of the present study was to update established reference ranges for lead in whole blood of healthy adults residing in Zaragoza and its region in northeastern Spain. The mean blo...

The aim of this study was to assess which of the equations that estimate peak power output and maximal oxygen uptake (VO2max) in the velodrome adapt best to the measurements made by reference systems. Thirty-four endurance cyclists and triathletes performed one incremental test in the laboratory and two tests in the velodrome. Maximal oxygen uptake...

Serum Mg is an important biochemical parameter in the context of clinical medicine for monitoring patients and for helping to diagnose some pathologies. The clinical laboratories must offer analytical results of quality in all parameters determined, demonstrating this way the laboratory "skill competence". The aim of this study was to revalidate (I...

Stricter regulations and controls for environmental lead have resulted in significantly lower frequency and reduced severity of chronic and acute lead intoxication. The aim of the present study was to update established reference ranges for lead in whole blood of healthy adults residing in Zaragoza and its region in northeastern Spain. The mean blo...

ISO 15189 standard establishes a requirement to periodically revalidate analytical methods for the determination of trace elements like Pb in blood, as conditions change and technical advances are made. The aim of this study was to revalidate an electrothermal atomic absorption spectrometry (ETAAS) method for determination of Pb in blood over the m...

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The aim of this study was to typify cardiorespiratory and metabolic adaptation capacity at race pace of high-level triathletes during simulations of short distance triathlon swimming sector, first transition and cycling sector. Six national and international-level triathletes performed a 1500 m swimming trial followed by a transition and one hour o...

In mammalian erythrocytes, outward fluxes by the Na-K-Cl cotransporter NKCC have been clearly characterized, but NKCC fluxes are small and their physiological role, if any, is poorly understood. Avian erythrocytes are nucleated cells, in which a physiologically relevant NKCC acts as a cell volume regulator. Therefore, we further investigated outwar...

Soy-based diets reduce blood pressure in spontaneously hypertensive rats, but apparently not in hypertensive humans. In the present study, the antihypertensive potential of soy milk (500 mL twice daily) compared with cow's milk was investigated in a 3-mo double-blind randomized study of 40 men and women with mild-to-moderate hypertension. Before in...

This study evaluates the consequences of a session of intensive short-duration exercise and Zn supplementation on different hematological variables. Forty male Wistar rats were divided into four groups (n=10): the first nonsupplemented, maintained at rest (R); the second nonsupplemented, undergoing exercise (E); the third supplemented with Zn, kept...

In order to study the response of plasma trace minerals during exercise in cold water at varying temperatures, three groups of ten male Wistar rats each were forced to swim until exhaustion in water at different constant temperatures (10, 20 and 32°C), while another 3 groups were kept at rest in water at the same temperatures and another group at r...

Bibliografía Conocer el interés de un grupo de estudiantes sobre las materias de primer ciclo, para algunos con unas ya cursadas y otras sin conocer su contenido para otros con todas conocidas, 163 alumnos del Colegio Universitario de Huesca, distribuidos como sigue: 58 de primero, 57 de segundo y 50 de tercero

Soy-based diets reduce blood pressure in spontaneously hypertensive rats, but apparently not in hy- pertensive humans. In the present study, the antihyperten- sive potential of soy milk (500 mL twice daily) compared with cow's milk was investigated in a 3-mo double-blind randomized study of 40 men and women with mild-to- moderate hypertension. Befo...

Bibliografía al final de los capítulos El objetivo general es comparar el rendimiento académico de un grupo de alumnos con Enseñanza asistida por ordenador (EAO) con otro que sigue un método de Enseñanza tradicional en la asignatura de Bioquímica, 24 alumnos elegidos al azar de la Escuela Universitaria de Medicina de Soria. Se les explicó conjuntam...