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14
Publications
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68
Citations
Citations since 2017
Introduction
saniva diagnostics GmbH, a spinoff of Jena University Hospital (Germany) develops a screening tool for early detection of neurodegenerative diseases (e.g. Parkinson's or Alzheimer's disease) and has applied for a European patent. With a specific motor screening instrument, patients at risk of neurodegenerative diseases should be identified earlier and thus benefit from a curative treatment approach, which is unique.
Skills and Expertise
Additional affiliations
August 2019 - July 2022
Saniva Diagnostics GmbH
Position
- Research Director
May 2015 - March 2020
Education
October 2010 - November 2014
Publications
Publications (14)
Aims:
Metabolic and structural perturbations in skeletal muscle have been found in patients with heart failure (HF) both with preserved (HFpEF) and reduced (HFrEF) ejection fraction in association with reduced muscle endurance (RME). We aimed in the current study to create phenotypes for patients with RME and HFpEF compared to RME HFrEF according...
Aims:
Both left atrial strain (LAS) and skeletal muscle endurance demonstrate a linear relationship to peak VO2 . Less is known about the relationship between central (cardiac) and peripheral (muscle endurance) limitations of exercise capacity in patients with heart failure (HF). We investigated this relationship using novel cardiac markers such a...
Aims
Left atrial strain (LAS) and skeletal muscle endurance demonstrate a linear relationship to peak VO2. Less is known about the relationship between central (cardiac) and peripheral (muscle endurance) limitations of exercise capacity in patients with heart failure (HF). We investigated this relationship using novel cardiac markers such as LAS an...
Mild motor abnormalities can herald the beginning of Parkinson´s disease but their diagnostic value is limited by multifactorial ageing-related influences on motor function. We characterized mild motor abnormalities in different motor domains by conducting a systematic motor assessment in 20 patients with clinically isolated REM sleep behaviour dis...
Aims:
Patients with heart failure (HF) suffer from reduced quality-of-life (QoL). We aimed to compare QoL, depression, and anxiety scores among outpatients with preserved (HFpEF) and reduced (HFrEF) ejection fraction and non-HF controls and its relationship to coordination capacity.
Methods and results:
Fifty-five participants were recruited pro...
BACKGROUND: Reduced exercise capacity in patients with heart failure (HF) could be partially explained by skeletal muscle dysfunction. We compared skeletal muscle function, structure, and metabolism among clinically stable outpatients with HF with preserved ejection fraction, HF with reduced ejection fraction, and healthy controls (HC). Furthermore...
Background The FED method (Fixation, Elongation, Derotation) is a treatment method approach to Patients with scoliosis. The FED method is especially established in Spain and Poland, whereby in Germany it is less well-known. Nevertheless the FED method is within the scope of a research project (Project Number: 19200 BR/3). The purpose of the paper i...
Treatment modalities of spinal pain patients are discussed diversely, and different multimodal therapy programs have been developed. Purpose of the present study was to evaluate therapy outcome and effectiveness of an inpatient interdisciplinary and multimodal treatment program.
This prospective multicentre clinical trial has been performed with pa...
Purpose: Patients with heart failure (HF) showed changes in skeletal muscle function structure and metabolism. We aimed to elucidate the differences in expression of growth factors and atrophy-related genes in skeletal muscle between clinically stable outpatients with HF with preserved (HFpEF) and reduced ejection fraction (HFrEF) and age-matched h...
Purpose: To elucidate exercise capacity, muscle strength and Quality of life (QoL) and the associated gene expression regulating metabolic, mitochondrial and structural characteristics among symptomatic and clinically stable outpatients with heart failure (HF) with both preserved (HFpEF) and reduced ejection fraction (HFrEF) and age-matching health...
Purpose In general, the purpose is to give a currently overview about conservative treatment methods (scoliosis specific physiotherapy) applied to treat adolescent idiopathic scoliosis (AIS). In particular, the FED-Method (Fixation, Elongation, Derotation), which is within the scope of a research project (Project Number: 19200 BR/3), is an object o...
Background
In order to keep up with developments in manual medicine (MM), at the turn of the millennium an extension of the corresponding curriculum was put forward. The continuing teaching of scientific knowledge and clinical experience could profit from this. The organizational and structural content in Germany is not restricted to university ins...
Background
The application of manual medicine in prevention is not a major topic. Within the framework of a research group project an attempt was made to find out whether the development of dysfunction and pain in the musculoskeletal system can be determined using manual diagnostic symptoms and signs of a developing dysfunction in an early time per...
