Jenny Alongi

Jenny Alongi
University of Milan | UNIMI · Department of Chemistry

Ph.D.

About

157
Publications
27,743
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
6,746
Citations
Introduction
J. Alongi currently works at the Department of Chemistry, University of Milan. She does research in Polymer Chemistry, Materials Chemistry and Nanotechnology. Research interests: •Synthesis and characterization of: • Chiral polymers with adhesion cellular properties • Bioactive, biodegradable and biocompatible polymers with antimalarial activity • Hydrogels as scaffolds for tissue engineering applications •Synthesis and characterization of polymers with high thermal stability and flame retardant properties; •Chemical grafting of synthesised polymers with desired properties, i.e. anti-bacterial, flame retardant properties, on cellulosic substrates.
Additional affiliations
October 2015 - present
University of Milan
Position
  • Research Assistant
September 2007 - September 2015
Politecnico di Torino
Position
  • Research Assistant
March 2003 - February 2006
Università degli Studi di Genova
Position
  • Research Assistant
Education
September 1996 - July 2002

Publications

Publications (157)
Article
Full-text available
The aza-Michael polyaddition of L-arginine and N,N′-methylene-bis-acrylamide gives the biocompatible and easily cell-internalized polyamidoamine ARGO7. By controlled synthesis, two ARGO7 oligomers, namely a trimer and a pentamer, bearing acrylamide terminal units, were obtained as precursors of the β-cyclodextrin-end-terminated oligomers P3 and P5,...
Article
The eco-compatibility of the glycine-derived polyamidoamine M-GLY, chosen as the benchmark for water-soluble polyamidoamines, was investigated by means of the seed germination test using watercress seeds. The percent germinated seeds and their root elongation were measured, and the corresponding germination index (GI) calculated for each set of dat...
Article
Full-text available
Linear polyamidoamines (PAAs) derived from the polyaddition of natural α-amino acids and N,N′-methylene bis(acrylamide) are intumescent flame retardants for cotton. Among them, the glycine-derived M-GLY extinguished the flame in horizontal flame spread tests at 4% by weight add-on. This paper reports on an extensive study aimed at understanding the...
Article
Full-text available
In this paper, bioinspired polyamidoamines (PAAs) were synthesized from N,N0 -methylene bisacrylamide and nine natural α-amino acids: L-alanine, L-valine, L-leucine (M-LEU), L-histidine, L-serine, L-asparagine, L-glutamine (M-GLN), L-aspartic acid and L-glutamic acid (M-GLU) and their performance as flame retardants (FRs) for cotton were determined...
Article
Full-text available
The hitherto known polyamidoamines (PAAs) are not suitable as structural materials because they are usually water-soluble or swellable in water. This paper deals with the synthesis and characterization of semi-crystalline hydrophobic PAAs (H-PAAs) by combining different bis-sec-amines with bis-acrylamides obtained from C6–C12 bis-prim-amines. H-PAA...
Article
Full-text available
This paper aims at elucidating the degradation mechanism of linear polyamidoamines (PAAs) in water. PAAs are synthesized by the aza-Michael polyaddition of prim-monoamines or bis-sec-amines with bisacrylamides. Many PAAs are water-soluble and have potential for biotechnological applications and as flame-retardants. PAAs have long been known to degr...
Article
Full-text available
D-and L-arginine-based polyamidoamino acids, called D-and L-ARGO7, retain the chirality and acid/base properties of the parent amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or surfaces was studied by choosing sodium deoxycholate (NaDC) as a m...
Article
Full-text available
This paper reports on synthesis, acid-base properties, and self-structuring in water of a chiral polyamidoamino acid, M-L-Gln, obtained from the polyaddition of N,N'-methylenebisacrylamide with L-glutamine, with the potential of establishing hydrogen bonds through its prim-amide pendants. The M-L-Gln showed pH-responsive circular dichroism spectra,...
Book
Full-text available
Recent disasters caused by the spread of fire in buildings and in transportations remind us of the importance of fire protection. Using flame-retardant materials is one important element of the firefighting strategy, which aims to prevent fire development and propagation. These materials are used in different applications, such as in textiles, coat...
Article
Full-text available
Gold nanoparticles are elective candidate for cancer therapy. Current efforts are devoted to developing innovative methods for their synthesis. Besides, understanding their interaction with cells have become increasingly important for their clinical application. This work aims to describe a simple approach for the synthesis of extra-small gold nano...
Article
Full-text available
The polyamidoamine derived from N,N′-methylenebisacrylamide (M) and glycine (G), M-G, has been shown to be an effective flame-retardant (FR) for cotton in horizontal flame spread tests (HFST), extinguishing the flame at 5% add-on. Its activity was attributed to its intrinsic intumescence. In vertical flame spread tests (VFST), M-G failed to extingu...
Article
Linear polyamidoamines containing disulphide groups (SS-PAAs) were prepared by polyaddition of L-cystine with 2,2-bisacrylamidoacetic acid (B-CYSS), N,N′-methylenebisacrylamide (M-CYSS) and 1,4-bisacryloylpiperazine (BP-CYSS). They were evaluated as flame retardants for cotton, alone or with cellulose-derived nano-graphene oxide (nGO) carbon dots,...
Article
Full-text available
Polyamidoamino acids (PAACs) are synthetic polymers prepared by the polyaddition of bisacrylamides with natural α-amino acids, which in the process maintain both their chirality and their amphoteric nature. This polymerization process is slow, but has the merits of taking place in water and of neither involving protection/de-protection steps nor re...
Article
The fate of macromolecules of biological or pharmacological interest that enter the mucus barrier is a current field of investigation. Studies of the interaction between the main constituent of mucus, mucins, and molecules involved in topical transmucoidal drug or gene delivery is a prerequisite for nanomedicine design. We studied the interaction o...
Article
Full-text available
The high flame-retardant loading required for ethylene-vinyl acetate copolymer blends with polyethylene (EVA-PE) employed for insulation and sheathing of electric cables represents a significant limitation in processability and final mechanical properties. In this work, melamine triazine (TRZ) and modified bentonite clay have been investigated in c...
Article
Full-text available
Chiral polyamidoamino acids were obtained by polyaddition of N,N'-methylenebisacrylamide with D-, D,L-and L-tryptophan (M-D-Trp, M-D,L-Trp and M-L-Trp). L-tryptophan/glycine copolymers, M-G-L-Trp 5 , M-G-L-Trp 10 , M-G-L-Trp 20 and M-G-L-Trp 40, were prepared from L-tryptophan/glycine mixtures. These polymers were amphoteric, with acid-base propert...
Article
Full-text available
This paper reports on synthesis, acid-base properties and self-structuring in water of chiral polyamidoamino acids (PAACs) obtained by polyaddition of N,N-methylenebisacrylamide with L-alanine, L-valine and L-leucine (M-L-Ala, M-L-Val, M-L-Leu) with potential for selective interactions with biomolecules. The polymers maintained the acid-base proper...
Article
Full-text available
The present manuscript deals with the reuse and valorisation of agricultural wastes and by-products (namely, hemp fibres and rice husk particles) to produce fire retardant fibreboards and particleboards for applications in biobuilding. Since fire retardancy is one of the most important challenges, a detailed study on the thermal and flame retardant...
Article
The layer-by-layer (LbL) assembly of chitosan (CH) and phosphorylated cellulose nanofibrils (P-CNF) is presented as a novel, sustainable and efficient fire protection system for polyurethane foams. The assembly yields a linearly growing coating where P-CNF is the main component and is embedded in a continuous CH matrix. This CH/P-CNF system homogen...
Article
Bioinspired polyamidoamines containing disulfide-groups in the main chain (SS-PAAs), prepared by Michael polyaddition of 2,2-bis(acrylamido)acetic acid with l-cystine (B-CYSS) and of N,N′-bis(acryloyl- l-cystine) with either glycine or 2-methylpiperazine (BACYSS-GLY and BACYSS-MP), were investigated as intumescent surface-confined flame retardants...
Article
Full-text available
Multilayered coatings deposited using the layer-by-layer (LbL) assembly technique have attracted great interest in recent years as a sustainable and efficient solution for conferring flame retardant properties to fabrics. The unique structure and interaction established upon the coating assembly are the key factors for successful flame retardant pr...
Article
Full-text available
In the present study, long hemp fibers and rice husk particles have been used for producing all natural-based boards for building, automotive and in-door furniture, employing a simple and economic transformation process (namely, compression molding). In order to have the required consistence and mechanical strength, cornstarch was employed as binde...
Article
Eight linear polyamidoamines (PAAs) prepared by polyaddition of amines to bisacrylamides are investigated as intumescent surface-confined flame retardants for cotton textiles. The structure of the amine-derived subunits governs their performances. In ignitability tests, aminoacid-deriving PAAs exposed to direct flame for 10 s do not burn, but produ...
Article
This work deals with the Layer by Layer (LbL) assembly of hybrid organic/inorganic flame retardant coatings made of Octa-ammonium POSS (polyhedral oligomeric silsesquioxane) and sodium montmorillonite clay on polyester (PET) fabrics. The effects of ionic strength on the achieved flame retardancy properties were investigated. The coating growth asa...
Article
Rice husk particles from agro-wastes have been treated with a Layer by Layer (LbL) deposition of polyelectrolytes and further assembled to prepare a bio-based particle board. The all polymer system employed uses a branched polyethyleneimine combined with a polyacrylic acid. The two polyelectrolytes show a super-linear growth as demonstrated by infr...
Article
AGMA1, a prevailingly cationic, guanidine-bearing, linear, amphoteric polyamidoamine is an effective siRNA condensing agent. Here two AGMA1 samples of different molecular weight, i.e. AGMA1-5 and AGMA1-10 were evaluated as siRNA condensing agents and transfection promoters. AGMA1-10 formed stable polyplexes with a size lower than 50 nm and positive...
Article
Full-text available
This work deals with the use of hydrotalcite nanoparticle post-diffusion in layer by layer (LbL) coatings with the aim of improving their flame retardant action on cotton. The selected LbL components, which encompass polydiallyldimethylammonium chloride and deoxyribonucleic acid, aim at the deposition of an intumescent coating. Infrared spectra poi...
Article
In this work, keratin fibres (KFs) were recovered from tannery industry wastes and reused for preparing completely green materials based on poly(lactic acid) (PLA) composites. A specific process for extracting and treating KFs as reinforcing and flame retardant agents for PLA was used. KFs were characterized by scanning electron microscopy, thermog...
Article
Full-text available
In the present manuscript a new concept of completely inorganic intumescent flame retardant nanocoating comprised of sodium montmorillonite nanoplatelets embedded in an ammonium polyphosphate matrix has been investigated using cotton as model substrate. The coating, deposited by multistep adsorption from diluted water-based suspensions/solutions, h...
Article
Full-text available
Over the last ten years a new trend of research activities regarding the flame retardancy of polymeric materials has arisen. Indeed, the continuous search for new flame retardant systems able to replace the traditional approaches has encouraged alternative solutions, mainly centred on nanotechnology. In this context, the deposition of nanostructure...
Article
Purpose – The cotton and its blends is the most commonly used textile material in the design and production of protective clothing. However, as the cellulose textiles are the most flammable materials it is necessary to improve its flame retardancy. The government regulations have been the driving force for developing durable flame retardants finish...
Article
One of the most important challenges for thermoplastic polymers is to find flame retardants (FRs) capable of efficiently protecting them. At the same time, these desired FRs should be environmentally sustainable, cheap and suitable for most of the polymers employed at industrial scale. Obviously, it is almost impossible to design such a universal F...
Article
The use of Layer by Layer (LbL) assembly for modifying the thermal stability and flammability of acrylic fabrics is proposed. Many efforts have been devoted to improve the flame retardancy of acrylic materials that vigorously burn, releasing dense smoke when exposed to a flame or a heat flux. In spite of this, no one has still attempted LbL as new...
Article
In this letter, we are presenting a novel approach for the deposition of Layer-by-Layer (LbL) coatings capable of conferring flame retardant properties to flexible polyurethane foams exploiting sub-second deposition times. The process yields nanoscale coatings able to reduce by 33% one of the main fire safety parameters, namely the heat release rat...
Article
The present article is addressed to investigating the effect of different fabric grammages (mass per area unit) on cotton combustion. To this aim, 100, 200 and 400 g/m2 cotton fabrics were tested when exposed to (1) two different heat fluxes (25 and 35 kW/m2) under a cone calorimeter, (2) a methane flame in horizontal or vertical flame spread tests...
Article
In the last five years, Layer by Layer (LbL) assembly has proven to be one of the most innovative solutions for conferring flame retardancy to fabrics. In spite of this, two main issues for the breakthrough of this approach at an industrial scale are still unsolved: namely, the use of few efficient layers characterized by washing durability. In thi...
Chapter
This chapter is aimed to thoroughly describe the thermal degradation of cellulose and cellulosic substrates (like cotton and paper), investigating the involved reaction mechanisms. After a brief introduction about the real reasons that motivated the study on cellulose degradation, a first general introduction on cellulose thermal degradation (namel...
Article
This paper deals with the Layer by Layer assembly of an all-polymer chitosan/poly(allylamine diphosphonate) coating characterized by high efficiency in reducing the flammability of open cell polyurethane foams. The Layer by Layer assembly of the two components yields a supralinear growing coating that can be easily deposited on the complex 3D struc...
Article
The present study was aimed to compare the effect of the presence of deoxyribose nucleic acid (DNA) or ammonium polyphosphate (APP) in ethylene vinyl acetate (EVA) copolymers, as far as their thermal and flame retardant properties are considered. Indeed, although DNA has been recently discovered as a novel green flame retardant, its performances ha...
Conference Paper
Flame retardant properties on semi-finished leather using sodium montmorillonite during retanned process were studied. Clay particles were dispersed within the leather structure. A flame retardant leather suitable for the aeronautic industry as upholstery product was obtained.
Article
The objective of current research on intumescent formulations is on consolidated approaches for conferring flame retardancy properties to polymers and polymer blends. Numerous academic and industrial efforts have been carried out in the last fifteen years, by revisiting the traditional concept of intumescence on the basis of the new chemical synthe...
Article
Cotton fabrics have been treated with two different finishing compositions based on urea (U) and ammonium dihydrogen phosphate (AP) in order to enhance their flame retardancy properties, particularly referring to the resistance to a flame application (namely, Limiting Oxygen Index tests) and to an irradiative heat flux of 35 kW/m2 (by cone calorime...
Article
Starch has been employed via layer by layer assembly for building an efficient and sustainable bio-based coatings capable of protecting cotton from fire. In order to obtain a better understanding of the coating to substrate relationship, the coating efficiency has been tested on cotton fabrics having different densities (i.e. 100, 200 and 400 g/m(2...
Article
First, polyamide (PA) 10,10-based compounds with enhanced flame retardant properties have been prepared by melt-blending. To this aim, a traditional intumescent formulation consisting of ammonium polyphosphate (APP) and pentaerythritol (PER) derived from oil chemistry has been added to PA 10,10 (30 wt.-% loading) and the resulting morphological, me...
Article
Deoxyribonucleic acid (DNA) has been mostly considered as a carrier of genetic information and gene expression. Recently, we have demonstrated that this biomacromolecule is very effective in providing cellulosic fabrics with flame retardant features, thanks to its intrinsic intumescent-like behaviour. Here, we have investigated the role played by d...
Article
Very recently, deoxyribonucleic acid (DNA) has proven to be an efficient renewable, natural flame suppressant and retardant, due to its intrinsic intumescent features. In our previous work, we have explored its flame retardant activity by applying as a surface coating on cotton fabrics and observed that on exposure to heat, the DNA was able to form...
Article
The preparation of 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide-functionalised polysilsesquioxane (Si-DOPO)-coating was described and its flame retardant efficiency for cotton fabric was thoroughly investigated. The 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide–vinyltrimethoxysilane (DOPO–VTS) was synthesized and applied to cotton fabric...
Article
As clearly reported in the scientific literature, the history of cotton flame retardancy is very old: this is easily attributable to the chemical and physical properties of this fibre that made it predominant during the 20th century; at present, it is only exceeded in volume by polyester. As a consequence, the huge number of papers published in the...
Article
The present work aims to investigate the layer by layer deposition of flame retardant thin coatings on closed cell polyethylene terephthalate foams. To this aim, two coating architectures have been selected in order to evaluate the efficiency of ammonium polyphosphate (APP) versus the freshly proved flame retardant deoxyribonucleic acid (DNA). Both...
Article
In the present paper we have demonstrated how the change of the layer by layer deposition parameters can influence the final properties of cotton fabrics in terms of coating morphology, thermal stability and flammability. To this aim, novel synthetized oligoallylamines and phosphonated oligoallylamines have been assembled on the surface of cotton e...
Article
Full-text available
The present paper critically analyzes the potential for commercially available nanoparticles for enhancing the flame-retardant properties of synthetic and natural fabrics and their corresponding blends. Each nanoparticle has been applied to the fabric through a finishing-like process (namely impregnation/exhausting or, more simply, nanoparticle ads...
Article
Full-text available
Silica powder has been extracted from rice husk, employing a simple extraction procedure for preparing poly(lactic acid) bio-composites with differ filler contents (namely, 5, 10, 20 and 30 wt.-%). These materials have been obtained through a semi-industrial process of extrusion. The thermal, mechanical and morphological properties have been invest...
Article
The selective and serial extraction of natural additives from hazelnut skin and cocoa by-products has been carried out for giving a high-added value to poly(lactic acid) and poly(propylene) (PLA and PP). Through the proposed process, three fractions mainly containing plasticizers, antioxidants and reinforcement fillers have been consecutively separ...
Article
The field of flame retardancy of polymeric materials (i.e. plastics, foams and in particular textiles) is currently facing several changes and challenges, as some of the current halogenated or phosphorus-based flame retardants (FRs) have proven to be persistent, bioaccumulative, carcinogenic and/or toxic for animals and humans. Thus, the seeking fo...
Article
In the present work, UV-curable layers have been exploited for assembling hybrid organic-inorganic Layer by Layer (LbL) coatings, able to enhance the thermo-oxidative stability and flame retardancy of polycarbonate (PC) films (500μm thick). More specifically, 5 or 10 quad-layers (QL), each consisting of a branched polyethylene imine, negative silic...
Article
Are nucleic acids and proteins intumescent molecules? In order to get an answer, in the present manuscript, powders of deoxyribose nucleic acids (DNA) and caseins have been exposed to different heat fluxes under a cone calorimeter source and to the direct application of a propane flame. Under these conditions, DNA and caseins exhibited a typical in...
Article
The present paper is aimed to review the state of the art on the novel and emerging techniques recently developed in the textile field for conferring flame retardant properties to natural and synthetic fibres. In particular, a comprehensive description of the results achieved by depositing (nano)coatings on the fabric surface through nanoparticle a...