Jennifer L Fore

• Northeastern University

To develop quantitative structure−spectroscopic property relationships in platinum acetylides, we investigated the triplet state behavior of nominally centrosymmetric chromophores trans-Pt(PBu3)2(C≡C-Phenyl-X)2, where X = diphenylamino, NH2, OCH3, t-Bu, CH3, H, F, benzothiazole, CF3, CN, and NO2. We measured ground state absorption, phosphorescence...

Operando Raman micro-spectroscopy of the membrane electrode assembly (MEA) of a fully operating hydrogen/oxygen Nafion electrolyte fuel cell is described. Coarse depth profiling of the fuel cell system enabled appropriate positioning of the microspectroscopy laser focal point for MEA catalytic layer spectroscopy. An increase in the ionomer state-of...

Instrumental advances in vibrational microspectroscopy have made possible the observation of individual human cells and even subcellular structures. The observed spectra represent a snapshot of the biochemical composition of a cell; this composition varies subtly but reproducibly with cellular effects such as progression through the cell cycle, cel...

Three two-photon absorption (TPA) dyes (Donor-π-Donor (DPA2F), Donor-π-Acceptor (AF240), and Acceptor-π-Acceptor (BT2F) type; specifically D is Ph2N-, A is 2-benzothiazoyl, and π-linker is 9,9-diethylfluorene) are examined in a variety of aprotic solvents. Because the TPA cross section is sensitive to the polarity of the local environment, this rep...

We study instantaneous two-photon absorption (2PA) in a series of nominally quasi-centrosymmetric trans-bis-(tributylphosphine)-bis- (4-((9,9-diethyl-7-ethynyl-9H-fluoren-2-yl) ethynyl)-R)-platinum complexes, where eleven different substituents, R = N(phenyl)2 (NPh2), NH2, OCH3, t-butyl, CH3, H, F, CF3, CN, benzothiazole (BT) and NO2, represent a r...

During the last 15years, vibrational spectroscopic methods have been developed, which can be viewed as molecular pathology methods that depend on sampling the entire genome, proteome, and metabolome of cells and tissues, rather than probing for the presence of selected markers. First, this review introduces the background and fundamentals of the sp...

During the last 15years, vibrational spectroscopic methods have been developed, which can be viewed as molecular pathology methods that depend on sampling the entire genome, proteome, and metabolome of cells and tissues, rather than probing for the presence of selected markers. First, this review introduces the background and fundamentals of the sp...

Platinum group metals (PGMs), i.e., palladium (Pd), platinum (Pt) and rhodium (Rh), are found at pollutant levels in the environment and are known to accumulate in plant and animal tissues. However, little is known about PGM toxicity. Our previous studies showed that chick embryos exposed to PGM concentrations of 1mL of 5.0ppm (LD(50)) and higher e...

The first study interpreting B-lymphocyte activation in normal lymph nodes using vibrational micro-spectral imaging is reported. Lymphocyte activation indicates the presence and response against a pathogen, regardless of the inciting pathogen's etiology, whether a benign, reactive or malignant process. Understanding the biochemical makeup of lympho...

We present results of an experimental photophysical study of a series of novel brominated and non-brominated porphyrins that contain phenyl, carbazole, or triphenylamine in the meso-position. In addition we have looked at the effects of incorporating a zinc metal into the porphyrin system relative to the free base. Structure-property relationships...

To develop a structure-spectroscopic property relationship in platinum acetylides having poly(aromatic hydrocarbon) ligands, we synthesized a series of chromophores with systematic variation in the number of fused aromatic rings (nFAR) and ligand topology (polyacene (L), polyphenanthrene (Z), or compact(C)). We measured ground-state absorption, flu...

A novel laboratory experiment was successfully implemented for undergraduate and graduate students in physical chemistry and nanotechnology. The main goal of the experiment was to rigorously determine the surface-enhanced Raman scattering (SERS)-based sensing capabilities of colloidal silver nanoparticles (AgNPs). These were quantified by estimatin...

To explore spectroscopic structure-property relationships in platinum acetylides, we synthesized a series of complexes having the molecular formula trans-bis(tributylphosphine)-bis(4-((9,9-diethyl-7-ethynyl-9H-fluoren-2-yl)ethynyl)-R)-platinum. The substituent, R = NH(2), OCH(3), N(phenyl)(2), t-butyl, CH(3), H, F, benzothiazole, CF(3), CN, and NO(...

A proposed tangential flow ultrafiltration method was compared to the widely used ultracentrifugation method for efficiency and efficacy in concentrating, size selecting, and minimizing the aggregation state of a silver nanoparticle (AgNP) colloid while probing the AgNPs' SERS-based sensing capabilities. The ultrafiltration method proved to be more...

To develop a structure-spectroscopic property relationship in platinum acetylides having poly(aromatic hydrocarbon) ligands, we synthesized a series of chromophores with systematic variation in the number of fused aromatic rings(nFAR) and ligand topology(polyacene(L), polyphenanthrene(Z) or compact(C)). We measured ground state absorption, fluoresc...

Silver nanoparticles (AgNPs) are currently receiving considerable attention because of their numerous applications in biology, pharmacy, and medicine. However, very little is known about their bioaccumulation and toxicity in living organisms. Animal model: To examine these aspects, developing chick embryos were injected twice with AgNPs (borohydrid...

The nonlinear photophysical properties of two-photon absorbing materials have been of great interest but have not been well understood. The Air Force Research Laboratory has developed a two-photon absorbing dye termed AF240 which consists of an electron donating group linked to a pi-conjugated center then to an electron withdrawing group. A solvent...

Recent studies showed that platinum group metals (PGMs) such as Pt, Pd, and Rh from automobile catalytic converters, can accumulate in the soft tissues of a variety of living organisms. However, the effects of PGMs on bone and organs development of animals are not clearly understood. To examine these aspects, developing chick embryos were injected...

There has been much interest in the development of two-photon absorbing materials and many efforts to understand the nonlinear absorption properties of these dyes. We have recently explored a new type of two photon absorbing dye containing a platinum center with ligands that vary in length that contain electron withdrawing benzothiazole. With incre...