Jelle Boonekamp

Jelle Boonekamp
University of Glasgow | UofG · Institute of Biodiversity, Animal Health and Comparative Medicine

PhD

About

38
Publications
5,510
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Citations
Introduction
Jelle Boonekamp is a lecturer/researcher and currently works at the IBAHCM, University of Glasgow. Jelle does research in life-history trade-offs, including senescence, oxidative stress and telomeres.
Additional affiliations
July 2020 - present
University of Glasgow
Position
  • Lecturer
Description
  • Lecturer and researcher in ecophysiology
September 2018 - present
University of Exeter
Position
  • Fellow
January 2014 - present
University of Groningen
Position
  • PostDoc Position

Publications

Publications (38)
Article
Full-text available
Telomere length and telomere shortening predict survival in many organisms. This raises the question of the contribution of genetic and environmental effects to variation in these traits, which is still poorly known, particularly for telomere shortening. We used experimental (cross‐fostering) and statistical (quantitative genetic ‘animal’ models) m...
Article
Full-text available
Understanding how species can thrive in a range of environments is a central challenge for evolutionary ecology. There is strong evidence for local adaptation along large‐scale ecological clines in insects. However, potential adaptation among neighbouring populations differing in their environment has been studied much less. We used RAD‐sequencing...
Article
Full-text available
Many organisms are capable of growing faster than they do. Restrained growth rate has functionally been explained by negative effects on lifespan of accelerated growth. However, the underlying mechanisms remain elusive. Telomere attrition has been proposed as a causal agent and has been mostly studied in endothermic vertebrates. We established that...
Preprint
Telomere length (TL) and shortening rate predict survival in many organisms. Evolutionary dynamics of TL in response to survival selection depend on the presence of genetic variation that selection can act upon. However, the amount of standing genetic variation is poorly known for both TL and TL shortening rate, and has not been studied for both tr...
Article
Because females produce and lay eggs or nurture embryos, they are constrained in the timing of their investment in reproduction. Males may have more opportunity to concentrate reproductive investment earlier in life, mating with as many females as possible soon after becoming adult. This fundamental difference leads to the prediction that because m...
Preprint
Full-text available
Many organisms are capable of growing faster than they do. Restrained growth rate has functionally been explained by negative effects on lifespan of accelerated growth. However, the underlying mechanisms remain elusive. Telomere attrition has been proposed as a causal agent and has been studied in endothermic vertebrates. We established that telome...
Article
Full-text available
1.The assumption that reproductive effort decreases somatic state, accelerating ageing, is central to our understanding of life‐history variation. Maximal reproductive effort early in life is predicted to be maladaptive by accelerating ageing disproportionally, decreasing fitness. 2.Optimality theory predicts that reproductive effort is restrained...
Article
Full-text available
Life-history theories of senescence are based on the existence of a trade-off in resource allocation between body maintenance and reproduction. This putative trade-off means that environmental and demographic factors affecting the costs of reproduction should be associated with changes in patterns of senescence. In many species, competition among m...
Article
Full-text available
Telomere length (TL) predicts health and survival across taxa. Variation in TL between individuals is thought to be largely of genetic origin, but telomere inheritance is unusual, because zygotes already express a TL phenotype, the TL of the parental gametes. Offspring TL changes with paternal age in many species including humans, presumably throug...
Article
Full-text available
The disposable soma theory of ageing predicts that when organisms invest in reproduction they do so by reducing their investment in body maintenance, inducing a trade‐off between reproduction and survival. Experiments on invertebrates in the lab provide support for the theory by demonstrating the predicted responses to manipulation of reproductive...
Article
Full-text available
Declines in survival and performance with advancing age (senescence) have been widely documented in natural populations, but whether patterns of senescence across traits reflect a common underlying process of biological ageing remains unclear. Senescence is typically characterised via assessments of the rate of change in mortality with age (actuari...
Article
Full-text available
Ecological conditions affect fitness, but mechanisms causing such effects are not well known, while evolved responses to environmental variation may depend on the underlying mechanisms. Consequences of environmental conditions vary strongly between traits, but a framework to interpret such variation is lacking. We propose that variation in trait re...
Preprint
Full-text available
Telomere length (TL) predicts health and lifespan in humans and other organisms, making the identification of the causes of TL variation of interest. At conception, zygotes inherit genes that regulate TL during early development, but at the same time already express a phenotype, which is the TL of the parental gametes that formed the zygote. Whethe...
Article
Full-text available
Telomere length (TL) has become a biomarker of increasing interest within ecology and evolutionary biology, and has been found to predict subsequent survival in some recent avian studies but not others. Here, we undertake the first formal meta-analysis to test whether there is an overall association between TL and subsequent mortality risk in verte...
Article
Full-text available
Oxidative stress shortens telomeres in cell culture, but whether oxidative stress explains variation in telomere shortening in vivo at physiological oxidative stress levels is not well known. We therefore tested for correlations between six oxidative stress markers and telomere attrition in nestling birds (jackdaws Corvus monedula) that show a high...
Article
Full-text available
Oxidative stress shortens telomeres in cell culture, but whether oxidative stress explains variation in telomere shortening in vivo at physiological oxi-dative stress levels is not well known. We therefore tested for correlations between six oxidative stress markers and telomere attrition in nestling birds (jackdaws Corvus monedula) that show a hig...
Article
Full-text available
Food availability modulates survival in interaction with (for example) competition , disease and predators, but to what extent food availability in natural populations affects survival independent of these factors is not well known. We tested the effect of food availability on lifespan and actuarial senescence in a large population of captive zebra...
Article
Full-text available
1. Biomarkers that predict fitness are instrumental in unravelling mechanisms that link environmental conditions to fitness. However, development is likely to be better canalized for traits with stronger fitness effects. As a consequence, traits that are sensitive to developmental conditions may be poor fitness predictors and vice versa, and we tes...
Article
Iteroparous organisms face a trade-off between reproduction and survival but knowledge of whether, how and when costs of long-term increases in workload are paid is scant. We increased locomotion costs for a whole year by equipping male great tits with a backpack during breeding, removing the backpacks one year later. We applied three different tre...
Article
Full-text available
Food and sex often go hand in hand because of the nutritional cost of reproduction. For Drosophila melanogaster females, this relationship is especially intimate because their offspring develop on food. Since yeast and sugars are important nutritional pillars for Drosophila, availability of these foods should inform female reproductive behaviours....
Article
Full-text available
Behaviour may contribute to changes in fitness prospects with age, for example through effects of age dependent social dominance on resource access. Older individuals often have higher dominance rank, which may reflect a longer lifespan of dominants, and / or an increase in social dominance with age. In the latter case, increasing dominance could m...
Article
Full-text available
Optimality theories of ageing predict that the balance between reproductive effort and somatic maintenance determines the rate of ageing. Laboratory studies find that increased reproductive effort shortens lifespan, but through increased short-term mortality rather than ageing. In contrast, high fecundity in early life is associated with accelerate...
Article
Full-text available
Developmental stressors often have long-term fitness consequences, but linking offspring traits to fitness prospects has remained a challenge. Telomere length predicts mortality in adult birds, and may provide a link between developmental conditions and fitness prospects. Here, we examine the effects of manipulated brood size on growth, telomere dy...
Article
Full-text available
Biomarkers of aging are essential to predict mortality and aging related diseases. Paradoxically, age itself imposes a limitation on the use of known biomarkers of aging, because their associations with mortality generally diminish with age. How this pattern arises is however not understood. With meta-analysis we show that human leucocyte telomere...
Data
Biomarkers of aging are essential to predict mortality and aging-related diseases. Paradoxically, age itself imposes a limitation on the use of known biomarkers of aging because their associations with mortality generally diminish with age. How this pattern arises is, however, not understood. With meta-analysis we show that human leucocyte telomere...
Article
Full-text available
The phenomenon of primary offspring sex ratio adjustment is being extensively studied, yet knowledge of the underlying proximate mechanism is still mainly hypothetical. Female birds are the heterogametic sex, thus potentially controlling the sex of the gamete to be fertilized. In several bird species, independent studies showed effects of maternal...
Article
Full-text available
Females often select mates on the basis of sexual signals, which can be reliable indicators of male quality when the costliness of these signals prevents cheating. The immunocompetence handicap hypothesis (ICHH) provides a mechanistic explanation of these costs, by proposing a trade-off between immune function and sexual displays. This trade-off ar...
Article
Full-text available
Submitted 126 The phenomenon of primary offspring sex ratio adjustment is being extensively studied, yet knowledge of the underlying proxi-mate mechanism is still mainly hypothetical. Female birds are the heterogametic sex, thus potentially controlling the sex of the gamete to be fertilized. In several bird species, independent studies showed effec...

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Projects

Projects (3)
Project
We aim to unravel mechanisms underpinning local adaptation using genetically divergent populations of wild field crickets along an altitude gradient. We are currently investigating the role of oxidative stress, telomere attrition and behavior as mechanisms underpinning life history trade-offs.
Project
Demographic, social and physiological aspects of life histories of free-living jackdaws
Project
Causes and consequences of variation in telomere length and dynamics in humans and animals