Jehad Yasin- Doctor of Medicine
- Student at University of Jordan
Jehad Yasin
- Doctor of Medicine
- Student at University of Jordan
Interested in Computational Systems Oncology and AI in Healthcare.
About
44
Publications
15,075
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
34
Citations
Introduction
Seeking multidisciplinary and methodologically-sound solutions for problems in Biology and Medicine.
Skills and Expertise
Current institution
Publications
Publications (44)
After asking the question: "Is reality (objective and independent) OR (subjective and perceived/interpreted)?" Here, I propose a framework of multiple subjective "realities" under one objective higher reality, shedding light on the dynamics of instantaneous objective reality. I introduce the idea of epistemic efficiency, defined as the ratio betwee...
e16257
Background: Biliary tract cancers (BTCs)—encompassing tumors of the bile ducts, gallbladder, or ampulla of Vater—are notoriously hard to manage, especially when surgery is off the table. Standard chemotherapy provides only modest benefits, and while emerging treatments such as immune checkpoint inhibitors and targeted drugs have shown promis...
Background:
Vault proteins, including MVP, VPARP, and TEP1, are components of the vault complex, and are involved in drug resistance, DNA repair, and cell survival. However, their role in low-grade gliomas (LGG) remains unclear. This study explored the expression and prognostic significance of LGG with the aim of uncovering their potential as bioma...
Introduction
Data regarding the role of dual antiplatelet therapy in patients with ischemic stroke or transient ischemic attack are limited. This study aimed to systematically review and analyze the efficacy and safety of dual antiplatelet therapy compared with aspirin alone in patients with acute ischemic stroke or transient ischemic attack.
Meth...
Background
Luminal A breast cancer (BC), the most common subtype of BC, often expresses the androgen receptor. This study explores androgen-regulated miRNA-mRNA interactions and their roles in metastasis, anoikis resistance, and metabolism.
Methods
Luminal A cell lines, MCF-7 and T47D, and the luminal androgen receptor (LAR) MDA-MB-453 cells, were...
Triple negative breast cancer (TNBC) is an aggressive form of cancer that has been subclassified into six molecular subtypes. One subtype, the luminal androgen receptor (LAR), which is characterized by over-expression of the androgen receptor (AR), confers the worst survival. In this work, we aimed to elucidate the androgen-regulated expression pro...
Background
Hepatobiliary cancers, which affect the liver, gallbladder, and bile ducts, are aggressive malignancies with a poor prognosis. Factors such as perineural invasion (PNI) can further complicate these cancers, as it can facilitate the spread of cancer cells to distant organs, reducing treatment effectiveness and overall survival. In this st...
Background: Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy with a higher case-fatality rate than melanoma. The prognosis of MCC is complex and depends on many factors. In this study, we aimed to develop predictive survival models using machine learning (ML) algorithms and statistical techniques for patients with head and...
Introduction
Cilostazol has been widely used to prevent peripheral vascular events after PCI. However, guidelines in cilostazol-based triple antiplatelet therapy for patients with ischemic heart disease undergoing PCI remain unclear. The purpose of this study was to assess the efficacy and safety of DAPT (aspirin and clopidogrel) compared to cilost...
Background and Objectives: Postoperative nausea and vomiting (PONV) notably affects up to
30% of surgical patients, resulting in elevated medical service costs, dehydration, discomfort,
and delayed recovery. Although standard antiemetic medications are effective, but they may not
completely prevent PONV due to complicated underlying pathophysiology...
Background
Prostate cancer treatment involves hormonal therapies that may carry cardiovascular risks, particularly for long-term use. Gonadotropin-releasing hormone (GnRH) antagonists, such as degarelix, may offer advantages over agonists, but comprehensive comparative cardiovascular outcomes are not well established. This study aimed to systematic...
Background: Stroke is the leading cause of neurological disability worldwide and contributes substantially to mortality. Colchicine is a microtubule inhibitor that has anti-inflammatory properties. In recent years, colchicine has been investigated as a potential therapeutic agent for reducing the risk of adverse cardiovascular events. Few studies h...
Background
Neural precursor cell expressed developmentally downregulated 9 (NEDD9) is considered an important factor in the progression of cancer, acting as a modulator of cellular migration, adhesion, and metastatic potential. Its significance as a prognostic factor, however, remains unclear, which necessitated a comprehensive review and meta-anal...
Background: Femoral access is predominantly used for mechanical thrombectomy in stroke patients with large vessel occlusions. Following interventional cardiology guidelines, routine radial access has been proposed as an alternative, though its safety and efficacy remain controversial. We aimed to evaluate the efficacy and safety of radial versus fe...
Background
Several screening models have recently been applied to study awareness and help people make informed decisions regarding cancer screening.
Aims
This study aimed to explore the knowledge, attitudes, and lung cancer screening health beliefs (LCSHBs) among Jordanians. Moreover, we intended to translate the LCSHBs scale into the Arabic lang...
Objective:
Indoleamine 2,3-dioxygenase-1 (IDO1) is a promising antitumor target and predictive biomarker in a variety of cancers. Hence, we performed this meta-analysis to evaluate the clinicopathological and prognostic significance of IDO1 in head and neck squamous cell carcinoma (HNSCC).
Methods:
We searched PubMed, Embase, Web of Science and Sco...
Hepatocellular carcinoma (HCC), the most common primary liver malignancy and the sixth most common cancer globally, remains fatal for many patients with inappropriate responses to treatment. Recent advancements in immunotherapy have transformed the treatment landscape for advanced HCC. However, variability in patient responses to immunotherapy high...
230
Background: Adrenocortical carcinoma (ACC) is a rare malignant neoplasm of the adrenal gland. Progressive forms of this cancer carry a dismal prognosis with 5-year survival rates < 40%. As such, predictors of stage progression and prognostic biomarkers are a must. Taste 2 receptors (TAS2Rs) are localized on the surface of bitter receptor cells....
Infective endocarditis (IE) is a severe infection of the inner lining of the heart, known as the endocardium. It is characterized by a range of symptoms and has a complicated pattern of occurrence, leading to a significant number of deaths. IE poses significant diagnostic and treatment difficulties. This evaluation examines the utilization of artif...
BACKGROUND: Cardiovascular diseases (CVDs) are a significant global health concern, causing an estimated 17.9 million deaths annually, which represents 31% of worldwide deaths. A significant proportion of CVD deaths are due to heart attacks and strokes, with one-third of these deaths occurring prematurely in individuals under 70 years old. Heart fa...
(1) Background: Earthquakes are natural disasters that often result in significant loss of life and property. The objective of this study is to explore the frequency of symptoms associated with posttraumatic stress disorder (PTSD), levels of meaning in life (ML), and perceived social support (SS) among university students in the aftermath of the ea...
Multilayer Perceptron (MLP) is a type of artificial neural network that is widely used in machine learning and data analysis. It is composed of multiple layers of interconnected nodes or neurons that process input data and generate output predictions. On the other hand, Tree-based models use a decision tree to represent how different input variable...
Introducing the main theoretical principles behind Bulk RNA-Sequencing. From RNA extraction into statistical and data analysis-based methods utilized to analyze RNA-Seq data.
All living organisms are made
up of small basic units called cells. Cells carry out a lot of metabolic processes, metabolic processes could be either catabolic or anabolic. Catabolic processes or reactions inside the cells use digested food molecules such as glucose to release energy. Respiration chain reactions take place to release energy from gl...
Genome editing is becoming more easy and efficient, CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 technology is significantly contributing to the improvement of gene editing processes. The CRISPR/Cas9 system allows site specific genomic targeting in all organisms. The new level of targeting, efficiency and ease of use of g...
Across the world, infertility affects about 15% of couples. Males are found to be solely responsible for 20-30% of infertility cases and contribute to 50% of cases overall. In the Middle East, the male factor is involved in 60-70% of infertile couples. Infertility can also be due to female factors or a combination of low infertility in both partner...
Inroducing the autonomic nervous system. Relating to deep links between the ANS and other organ systems, and the pathophysiology as well.
BACKGROUND: Cardiovascular diseases (CVDs) are a significant global health concern, causing an estimated 17.9 million deaths annually, which represents 31% of worldwide deaths. A significant proportion of CVD deaths are due to heart attacks and strokes, with one-third of these deaths occurring prematurely in individuals under 70 years old. Heart fa...
