Jeffrey V LazarusInstituto de Salud Global de Barcelona | ISGLOBAL
Jeffrey V Lazarus
MA, MIH, PhD
About
883
Publications
177,013
Reads
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53,165
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Introduction
Leading a research group at Spain's global public health centre of excellence, the Barcelona Institute for Global Health (ISGlobal), that is working at the interface of health systems and communicable diseases - with a particular focus on viral hepatitis and HIV. Chair of The Lancet HIV Fourth 90 Commission and working group chair of the EASL-Lancet European Liver Health Commission. Recognised for launching the "Fourth 90" in HIV and the "micro-elimination" approach in HCV.
Additional affiliations
November 2017 - present
May 2016 - April 2019
June 2015 - present
BioMed Central
Position
- Editor-in-Chief
Description
- HMAP considers articles on the prevention and management of viral and non-viral hepatitis and other liver disorders, including articles on the public health, policy and biomedical dimensions of these conditions: http://www.hmap.biomedcentral.com/
Education
March 2014 - March 2014
September 2004 - March 2008
January 2002 - August 2003
Publications
Publications (883)
https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2023
https://www.aasld.org/the-liver-meeting
https://www.aasld.org/the-liver-meeting
https://www.aasld.org/the-liver-meeting
https://www.aasld.org/the-liver-meeting
Current treatment of metabolic dysfunction-associated steatotic liver disease focuses on adjusting patients’ lifestyles, including promoting weight loss and physical activity. Here, we suggest adopting a holistic preventive hepatology approach encompassing social nutrition, social prescribing and broader societal changes to facilitate individuals’...
About Non alcoholic fatty liver disease-Policy
While gastroenterologists and hepatologists may be pivotal in addressing the huge unmet need of managing prevailing obesity-related sequelae, we would also suggest that, beyond these professionals, there are other key stakeholders, including specialists in public health, metabolic medicine, endocrinology and obesity, maternal medicine, paediatrics...
The hepatitis C virus (HCV), a single-stranded RNA virus belonging to the Flaviviridae family, is a major cause of hepatocellular carcinoma (HCC) worldwide. Tumors caused by HCC have an increased mortality rate globally, which is more accentuated in Western countries. The carcinogenic potential of this virus is mediated through a wide range of mech...
Background and Aims: Fatty liver disease is highly prevalent, resulting in overarching wellbeing and economic costs. Addressing it requires compre
Background:
HIV stigma and discrimination are drivers of adverse HIV outcomes because they deter individuals from engaging in the HIV care continuum. We estimate the prevalence of public stigma towards people with HIV, investigate individuals' sociodemographic determinants for reporting stigmatizing attitudes, and test the impact of HIV stigma on...
Background:
In 2016, the World Health Assembly adopted the resolution to eliminate viral hepatitis by 2030. This study aims to provide an overview of the burdens of hepatitis B virus (HBV) and hepatitis C virus (HCV) in Europe and their changes from 2010 to 2019 using estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (...
The AIDS epidemic has been a global public health issue for more than 40 years and has resulted in ~40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted via body fluids and secretions. After infection, the virus invades host cells by attaching to CD4 receptors and thereafter one of two major chemokine coreceptors, CCR5 o...
"“Action without vision is only passing time, vision without action is merely daydreaming, but vision with action can change the world.” - Nelson Mandela"
On 22 May 2023, at the Geneva headquarters of the European Association for the Study of the Liver (EASL), we convened a groundbreaking event on the sidelines of the 76th World Health Assembly (W...
Summary
Background
The 2016 World Health Assembly endorsed the elimination of hepatitis B virus (HBV) infection as a public health threat by 2030; existing therapies and prophylaxis measures make such elimination feasible, even in the absence of a virological cure. We aimed to estimate the national, regional, and global prevalence of HBV in the gen...
Objectives
This study aimed to report the prevalence and identify potential risk factors of chronic conditions among West African migrants living in the greater Barcelona area, Spain, and explore the relationship between years of residence in Spain and chronic disease burden.
Methods
This cross-sectional study included 436 adult African migrants w...
Background aims:
Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions are urgently needed to target disease prevention, treatment, and care.
Approach results:
We developed an aligned, prioritized action agenda for the global fatty liver diseas...
Unlabelled:
The principal limitations of the terms nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favour of a change in nomenclature a...
Unlabelled:
The principal limitations of the terms nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favour of a change in nomenclature a...
https://easl.eu/event/easl-congress-2023/
https://www.easlcongress.eu/
Background:
The number of migrants in the European Union (EU) has been growing, including migrants at risk of using drugs. Little information is available on the actual drug use among first-generation migrants who use drugs in the EU, nor on their access to drug dependency services. This study aims to reach consensus among experts in the EU on the...
Background & aims
An estimated 38% of adults worldwide have NAFLD. From individual impacts to widespread public health and economic consequences, the implications of this disease are profound. This study aimed to develop an aligned, prioritised research agenda for the global fatty liver disease community of practice.
Methods
Nine co-chairs drafted...
Unlabelled:
The principal limitations of the terms nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favour of a change in nomenclature a...
Background
COVID-19 has hindered hepatitis C virus (HCV) and HIV screening, particularly in marginalised groups, who have some of the highest rates of these conditions and lowest rates of COVID-19 vaccination. We assessed the acceptability of combining HCV testing with COVID-19 vaccination in a centre for addiction services (CAS) in Barcelona and a...
Globally, the use of digital health interventions (DHIs) is expanding, along with growing scientific evidence of their effectiveness. Given the high and increasing prevalence of noncommunicable liver disease, we surveyed 295 physicians across Spain about their knowledge, beliefs, attitudes, practices, and access with regard to DHIs for patient care...
One of the key at-risk populations for hepatitis C virus infection (HCV) are people who use drugs (PWUD) given that they are a vulnerable population due to the stigma, discrimination and socioeconomic inequalities. They often have difficulties in accessing healthcare and are therefore at increased risk of infection, access treatment less often, and...
The COVID-19 pandemic has hindered efforts to address the hepatitis C virus (HCV) and HIV by reducing testing, particularly in marginalised groups, who have some of the highest rates of these conditions and lowest rates of COVID-19 vaccination.
Background & Aims:
Fatty liver disease is highly prevalent, resulting in overarching wellbeing and economic costs. Addressing it requires comprehensive and coordinated multisectoral action. We developed a fatty liver disease-Sustainable Development Goal (SDG) country score to provide insights into country-level preparedness to address fatty liver...
https://www.eccmid.org/
COVID-19 vaccination has resulted in decreased hospitalization and mortality, particularly among those who have received a booster. As new effective pharmaceutical treatments are now available and requirements for non-pharmaceutical interventions (e.g. masking) are relaxed, perceptions of the risk and health consequences of SARS-CoV-2 infection hav...
https://hr23.hri.global/
Background:
Limitations of current global health governance revealed during the COVID-19 pandemic can inform the ongoing deliberations for an international treaty on pandemics.
Objectives:
To report on World Health Organization (WHO) definitions for governance and the enforcement of treaties in the context of a proposed international treaty on p...
Hepatitis D virus (HDV) infection occurs as a coinfection with hepatitis B and increases the risk of hepatocellular carcinoma, decompensated cirrhosis, and mortality compared to hepatitis B virus (HBV) mono-infection. Reliable estimates of HDV infection prevalence and disease burden are essential to formulate strategies to find coinfected individua...
https://amcpannual.org/about/about-amcp-2023
The Russian military invasion of Ukraine on February 24, 2022, resulted in the largest refugee crisis in Europe since World War II. As a neighboring country to Ukraine, Poland was the main country to initially receive refugees. Between February 24, 2022, and February 24, 2023, 10.056 million refugees from Ukraine, mainly women and children, crossed...
INTRODUCCIÓN En España los antivirales de acción directa (AAD) para tratar la infección del virus de la hepatitis C (VHC) han sido accesibles para toda la población desde el 2017. Aun así, hay poblaciones vulnerables y con escasa vinculación a la asistencia sanitaria que tienen dificultades para acceder al tratamiento del VHC, como son las personas...
Over the past few decades, the life expectancy of people living with HIV has markedly improved due to the advances in HIV diagnosis, linkage to care, and treatment. However, with these advances, a new set of challenges has emerged that must be addressed to ensure the long-term well-being of people living with HIV. In this article, as part of a wide...
Objectives:
In recent decades, the needs of people living with HIV have evolved as life expectancy has greatly improved. Now, a new definition of long-term success (LTS) is necessary to help address the multifaceted needs of all people living with HIV.
Methods:
We conducted a two-phase research programme to delineate the range of experiences of...
http://www.optimisingcare.com.au/
Left unaddressed, NAFLD will continue to have substantial health, economic and social implications. To address the challenge, a paradigm shift is needed in the way NAFLD is conceptualised. Concerted, collaborative action across medical specialities, industry sectors and governments will be vital to tackling this public health threat. To drive this...
NAFLD is a multisystem condition and the leading cause of chronic liver disease globally. There are no approved NAFLD-specific dugs. To advance in the prevention and treatment of NAFLD, there is a clear need to better understand the pathophysiology and genetic and environmental risk factors, identify subphenotypes, and develop personalized and prec...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continued to mutate and spread in 2022 despite the introduction of safe, effective vaccines and medications. Vaccine hesitancy remains substantial, fueled in part by misinformation. Our third study of Coronavirus Disease 2019 (COVID-19) vaccine hesitancy among 23,000 respondents in 23 cou...
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent globally and requires multidisciplinary care. Here, we report key findings of a NAFLD care workshop, address knowledge gaps and highlight a path to optimise healthcare resource use, to improve outcomes in patients with steatotic liver disease. Schattenberg et al. outline discussions from...
