Jeffrey A Larson

Washington University in St. Louis | WUSTL , Wash U · Division of Urologic Surgery

Purpose The goal of this study was to compare the rate of systemic inflammatory response syndrome (SIRS) in high-risk patients undergoing percutaneous nephrolithotomy (PCNL) between patients who received 7, 2, or 0 days of preoperative antibiotics. Materials and Methods We retrospectively reviewed a series of consecutive PCNLs performed at our ins...

Objective: To evaluate the outcomes of robot-assisted partial nephrectomy RAPN after major prior abdominal surgery (PAS) using a large multicentre database. Patients and methods: We identified 1 686 RAPN from five academic centres between 2006 and 2014. In all, 216 patients had previously undergone major PAS, defined as having an open upper midl...

Objective: To develop an evidence-based approach to the diagnostic workup of suspicious upper urinary tract lesions. Methods: The PubMed database was searched using the following terms with a filter for English language: "upper tract urothelial carcinoma," "upper tract transitional cell carcinoma," along with the corresponding terms: "cost," "ep...

Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS) commonly affect older men. Age-related changes associated with metabolic disturbances, changes in hormone balance, and chronic inflammation may cause of BPH development. The diagnosis of BPH hinges on a thorough medical history and focused physical examination, wi...

Introduction Expert reported outcomes and complications may not reflect the standardized coding that can be provided by independent, third party evaluations. The goal of this paper is to compare expert reported complications to standardized coding by the National Surgical Quality Improvement Program (NSQIP). The procedures evaluated were laparoscop...

The objective of this study was to evaluate surgical outcomes with respect to the experience level of the bedside assistant during robot-assisted partial nephrectomy. A retrospective review was conducted of a prospectively maintained database of 414 consecutive robot-assisted laparoscopic partial nephrectomies performed by experienced robotic surge...

Purpose: To compare perioperative outcomes, specifically hospital length of stay (LOS), after retroperitoneal and conventional transperitoneal robot-assisted partial nephrectomy (RAPN). Patients and methods: We retrospectively compared consecutive patients with a posterior renal mass undergoing retroperitoneal RAPN (n=116) versus transperitoneal...

The incidence of renal cell carcinoma continues to increase with utilization of diagnostic abdominal imaging with migration towards a proportionally greater detection of small renal masses (SRM). Robot-assisted partial nephrectomy (RAPN) has become an attractive minimally invasive treatment modality for SRM's due to the technical advantages and sho...

Introduction/objective: Robotic-assisted partial nephrectomy (RPN) offers a mean length of stay (LOS) of 2 to 3 days. The purpose of this study is to determine the impact of modifiable and nonmodifiable risk factors on hospital LOS after RPN. Patients and methods: We retrospectively reviewed our prospectively maintained database to identify all...

Objective To compare the perioperative outcomes of RPN with LPN performed for SRMs, in a large multi-institutional series.To define a new composite outcome measure, termed “ optimal outcome” for the RPN group.Patients and Methods Retrospective review of 2392 consecutive cases of RPN and LPN performed in 5 high volume centres from 2004 to mid 2013.W...

Objective To evaluate the outcomes of robot‐assisted partial nephrectomy RAPN after major prior abdominal surgery (PAS) using a large multicentre database. Patients and methods We identified 1 686 RAPN from five academic centres between 2006 and 2014. In all, 216 patients had previously undergone major PAS, defined as having an open upper midline/...

Objective: To determine if patients with pathological, medical renal disease, defined as evidence of pathological abnormalities indicative of renal damage in the non-neoplastic partial nephrectomy specimens, have worsened functional outcomes following robot-assisted partial nephrectomy (RPN). Materials and methods: Sixty patients with and 101 wi...

Purpose: To compare the perioperative outcomes of robot-assisted partial nephrectomy (RAPN) with open partial nephrectomy (OPN) in solitary kidneys. Methods: Records of 1542 consecutive RAPN performed in five high-volume centers (2007-2013) were reviewed for patients with solitary kidneys. Results were compared with solitary OPN cases performed d...

Purpose: We evaluated a published biopsy directed small renal mass management algorithm using a large cohort of patients who underwent robotic partial nephrectomy for tumors 4 cm or smaller. Materials and methods: A simplified algorithm of biopsy directed small renal mass management previously reported using risk stratified biopsies was applied...

To evaluate the effects of a reverse thermosensitive polymer during ureteroscopy with laser lithotripsy in an in-vivo porcine model. Six pigs underwent general anesthesia followed by bilateral ureteroscopy with laser lithotripsy of stone phantoms while measuring intrapelvic renal pressures through bilateral nephrostomy tubes. The procedures were pe...