Jeanne Hersant

Jeanne Hersant
University of Angers | UA · vascular medicine

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41
Publications
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Introduction

Publications

Publications (41)
Article
Introduction La thromboangéite oblitérante (TO) est une maladie inflammatoire non athéroscléreuse, segmentaire, qui affecte les artères et veines de petits à moyens calibres au niveau des membres supérieurs et inférieurs principalement, chez des hommes jeunes, de 20 à 40 ans, tabagiques. Son étiologie exacte reste mal connue, mais on sait qu’il exi...
Article
Objective It was hypothesised that there is a linear relationship between the severity of exercise induced calf ischaemia and the prevalence of calf claudication on a treadmill until a plateau is reached. It was expected that no pain would be present in the absence of ischaemia and all severely ischaemic calves would be symptomatic. Methods This w...
Article
Background Behçet’s disease (BD) is a rare form of systemic vasculitis that affects small to large vessels. It is characterized by mucocutaneous, pulmonary, cardiovascular, gastrointestinal, and neurological manifestations. Large vessel involvement may occur in a third of cases. Veins are usually more affected than arteries. Furthermore aneurysms a...
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Objective Thoracic outlet syndrome (TOS) should be considered of arterial origin only if patients have clinical symptoms that are the result of documented symptomatic ischemia. Simultaneous recording of inflow impairment and forearm ischemia in patients with suspected TOS has never been reported to date. We hypothesized that ischemia would occur in...
Article
The aim of this study was to identify clinical factors associated with exercise-induced vasculitis (EIV). This study included EIV cases and controls matched for age. Cases included were all members of a hiking club and participated in extended hiking trips. Exercise-induced vasculitis was diagnosed based on clinical signs occurring only after prolo...
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Objective: Fingertip photoplethysmography (PPG) resulting from high-pass filtered raw PPG signal is often used to record arterial pulse changes in patients with suspected thoracic outlet syndrome (TOS). Results from venous (low-pass filtered raw signal) forearm PPG (V-PPG) during the Candlestick-Prayer (Ca + Pra) maneuver were recently classified i...
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Aim: A better knowledge of the biological consequences in the blood of these exercise-induced ischemic events in lower extremity artery disease (LEAD) may improve the prospects of disease management. We explored the preminus postexercise metabolomic difference in 39 patients with LEAD referred for a treadmill oximetry test [transcutaneous oximetry...
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Purpose: This study investigated the correlations of hemodynamic parameters measured to quantify stenosis between the gold-standard duplex ultrasonography and the dual-gate Doppler mode. Methods: Patients examined due to suspicion of carotid artery stenosis or for surveillance of known stenosis were invited to participate in this prospective sin...
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PurposeMany tasks, sports or leisure activities require maximal knee flexion. We hypothesized that this position could result in reduced calf perfusion, in young European subjects.Methods We quantified calf ischemia resulting from the knee flexion with transcutaneous oxygen pressure (TcpO2) sensors by assessing the decrease from rest of TcpO2 (DROP...
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Aortic wall ¹⁸ F-fluorodeoxyglucose (FDG)-uptake does not allow differentiation of aortitis from atheroma, which is problematic in clinical practice for diagnosing large vessel vasculitis giant-cell arteritis (GCA) in elderly patients. The purpose of this study was to compare the FDG uptake characteristics of GCA aortitis and aortic atheroma using...
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The level of pulse amplitude (PA) change in arterial digital pulse plethysmography (A-PPG) that should be used to diagnose thoracic outlet syndrome (TOS) is debated. We hypothesized that a modification of the Roos test (by moving the arms forward, mimicking a prayer position (“Pra”)) releasing an eventual compression that occurs in the surrender/ca...
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Background Upper extremity venous thrombosis (UEVT) represents about 10% of venous thrombo-embolic disease. This is mainly explained by the increasing use of central venous line, for oncologic or nutritional care. The factors associated with venous recanalization are not known.Objective The aim of this study was to investigate prognosis factor asso...
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Objective: Post-thrombotic syndrome (PTS) is one of the main complications that occurs after venous thrombosis. There is little data on the proportion of patients that will develop upper extremity PTS (UE-PTS) after upper extremity venous thrombosis (UEVT). The main objective of the study was to assess the prevalence of PTS in a UEVT cohort and to...
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Objective: Hemodynamic investigations in thoracic outlet syndrome (TOS) remain difficult, even in trained hands. Results are generally reported as either presence or absence of venous compression. In fact, in patients with suspected TOS but without chronic venous occlusion, the forearm volume changes may result from various combinations of forearm...
Article
Background: Thromboangiitis obliterans (TAO) is a distal non atherosclerotic thrombotic vasculitis affecting tobacco smokers. The role of cannabis co-exposure remains controversial. The study aims to assess how cannabis consumption influences clinical presentation and outcome of TAO in tobacco smokers. Patients and methods: TAO patients, according...
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Background and aims Transcutaneous oxygen pressure (TcpO2) is used in patients with suspected critical limb ischemia (CLI). Sinusoidal changes (SC~) in TcpO2 are found in patients with Cheyne-Stokes respiration (CSR). We aimed to determine the characteristics of TcpO2 changes at rest in patients with suspected CLI, define the objective criteria for...
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Background Previous studies in patients with arterial claudication have focused on calf hemodynamic recovery. We hypothesized that the duration of hemodynamic recovery with TcpO2 at calf and non-calf levels would be shorter than 10 min. We analyzed the factors that influence the recovery time. Methods We monitored limb changes minus chest changes...
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Background and aims Calf pain is the most frequent symptom of arterial claudication. We hypothesized that patients with self-reported isolated calf claudication have frequent exertional non-calf symptoms during objective laboratory testing, and that many would show not only distal, but also proximal ischemia. Methods We retrospectively analyzed th...
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Background Galvanic current-induced vasodilation (CIV) is impaired in patients under low-dose aspirin (ASA; ≤ 500 mg/day), but potential covariates and the impact of the time since the last ASA intake are unknown. Objectives We used tissue viability imaging (TiVi) in patients at risk of cardiovascular disease and examined its association with self...
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Background: Epidemiological, imaging, and anatomical studies suggest an association between proximal arterial atherosclerosis and development of low back pain (LBP). Objectives: We aimed to define (1) the frequency and (2) factors associated with exercise-induced proximal ischemia (EIPI) in individuals with LBP and (3) develop a clinical screeni...
Article
Transcutaneous oxygen pressure (TcpO2) measurement has been used for years at rest in patients with lower extremity artery disease. It was proposed for exercise testing (Ex-TcpO2) in the 80ies to evaluate regional blood flow impairment (RBFI) at the proximal and distal levels simultaneously and on both sides, in case of claudication. It was suggest...
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Aim: To compare the transcutaneous oxygen pressure results observed in patients with severe walking limitation during standard procedures (3.2 km/h, 10% slope) versus during a test performed at a low speed (2 km/h, 10% slope). Methods: In 31 patients the decrease from rest of oxygen pressure (DROP) index was measured on both buttocks, both thigh...
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To study the concordance of exercise-oximetry and of ankle-brachial pressure index (ABI) and ankle pressure (AP) at rest, and after exercise, in patients complaining of vascular-type claudication to diagnose lower extremity artery disease (LEAD). Treadmill test in 433 patients with exercise-oximetry included constant load (3.2 km/h, 10% slope) phas...
Article
Objective: To compare the different techniques for the treatment of carotid restenosis after carotid artery endarterectomy (CAE). Methods: Among 1218 carotid surgeries carried out in our center between January 2010 and November 2017, 45 procedures were performed for carotid restenosis after CAE, including 11 by iterative conventional surgery and...
Article
Background: Non-invasive tests are still required to improve the holistic diagnostic approach of thoracic outlet syndrome (TOS). Objectives: We aimed to analyze the diagnostic accuracy of the decrease from rest oxygen pressure (DROP) index of transcutaneous oximetry (TcpO2) in TOS. Methods: Seventy-six patients and 40 asymptomatic volunteers (...
Article
BACKGROUND: Measurement of ankle and brachial blood pressure after maximal exercise is largely used to diagnose exercise-induced arterial endofibrosis (EIAE). AIMS AND OBJECTIVES: We aimed to compare the different available methods and combination of these and propose a method based on graphical interpretation, for the diagnosis of EIAE. MATERIAL...
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Background: The prevalence of cardiovascular diseases is increasing in low-income countries. Various questionnaires to estimate walking capacity in patients are available in multiple languages but they are not suitable for illiterate patients. Objective: The walking estimated limitation stated by history (WELSH) tool aims at rating individual wa...
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Objective: To determine if using a telephone can induce forearm pain and ischemia. Design: Prospective case-control trial. Setting: Vascular laboratory in the university hospital in Angers between September 2018 and March 2019. Participants: Fifteen apparently healthy subjects (controls) and 32 patients with suspected thoracic outlet syndrom...
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Tyrosine kinase inhibitors are considered as highly effective and relatively safe drugs for the treatment of chronic myeloid leukemia. If several side effects on short and long term are well known and described, their involvement in the development of carotid stenosis remains unclear. Here, we describe a case of carotid stenosis in a patient receiv...
Article
Objective: Determining the maximum walking time (MWT) using the treadmill test is the gold standard method for evaluating walking capacity and treatment effect in patients with peripheral arterial disease (PAD). However, self reported functional disability is important when assessing quality of life. Changes in the Walking Estimated Limitation Cal...
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Introduction Le Nilotinib est un inhibiteur de tyrosine kinase (ITK) de seconde génération et constitue un des traitements majeurs de la leucémie myéloïde chronique (LMC). Ses effets indésirables à court terme ont été bien étudiés mais de nombreuses interrogations persistent sur le long terme. Suite à différentes études montrant le rôle de ce trait...
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Background: Exercise oximetry allows operator-independent recordings of microvascular blood flow impairments during exercise and can be used during upper arm provocative maneuvers. Objective: To study the test-retest reliability of upper-limb oximetry during the Roos test in patients with suspected thoracic outlet syndrome (TOS). Materials and Meth...
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Background The prevalence of exercise-induced ischemia in the asymptomatic limb of patients with unilateral claudication based on history and treadmill evaluation, and with unilateral ipsilateral peripheral artery disease (i.e ankle-to-brachial systolic pressure index <0.90) is unknown. Methods We detected exercise-induced ischemia in the asymptom...
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Background: Forearm cutaneous blood flux (CBF) measurement with post-occlusive reactive hyperemia (PORH) is uncomfortable and may not be devoid of risks. We aimed to investigate post-compression reactive hyperemia (PCRH) with a custom-made indenter that was designed to be easily used routinely by inexperienced observers. Methods: Medical students e...
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We read with interest the recent article by Vriens et al. published in Diabetic Medicine [1]. The authors question the screening tools used to test for the presence of peripheral artery disease in people with diabetic foot ulcers. This is important because the complications of diabetes limit all commonly used, non‐invasive, bedside tests for periph...
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BACKGROUND: This study is to assess the applicability and performance of the near-infrared spectroscopy (NIRS) in the diagnosis of exercise-induced arterial endofibrosis (EIAE). METHODS: NIRS was measured on each thigh, in 12 highly trained asymptomatic cyclists (controls) and 14 EIAE patients highly trained competition cyclists. All patients had...

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