Jeanet Rodriguez Mayusa

• University of Applied and Environmental Sciences

Ethanol and n-hexane extracts obtained from the leaves and inflorescences of Gnaphalium gracile, were tested at different concentrations to evaluate their antineoplastic activities on pancreatic, colon, and prostate cancer cell lines by examining mitochondrial function. The polar extracts of both, leaves and inflorescences which contain gnaphalin,...

Background: Flavonoids isolated from plants have demonstrated an important role in cancer chemoprevention and chemotherapy. The genus Cromolaena has been shown to have active principles against this disease and found in species such as C. odorata, and C. laevigata in a concentration lower than 100 mg/L, however, flavonoids from C. leivensis has not...

Objetive: To determine the antioxidant and antiproferative activity of the flavonoids isolated from the leaves of Chromolaena tacotana. Methods: Extraction was carried out with dichloromethane (CH2Cl2) from the leaves by soxhlet, the flavonoids were isolated by column chromatography (Si gel G 60-200 microns 4 x 60cm) eluted with CHCl 3 , mixtures o...

From the extract in dichloromethane (CH2Cl2) from the leaves of Chromolaena tacotana, flavonoids were isolated by column chromatography (Si gel G 60-200 microns 4x60cm) eluted with CHCl3 , mixtures of CHCl3: MeOH and MeOH:These compounds were identified as (Ct1) 3,5,4'-trihydroxy-7-methoxyflavone, (Ct2) 3,5,8-trihydroxy-7,4'dimethoxyflavone (Ct3) 4...

To obtain a scientific basis and justification of plant domestication in the use of Ageratina gracilis, we did an in vitro study of the anticancer potential of extracts and fractions from its leaves and inflorescences. Firstly, cytotoxicity was evaluated against five human tumorigenic cell lines by MTT assay. Subsequently, the chloroformic fraction...

Over 5000 flavonoids have been identified so far and many of these are known to have antineoplastic properties. The relationships between the targeting activities by these compounds on cancer cells and the specific features that determine their molecular structures are not completely elucidated. Here we report the differential cytotoxic effects of...

The flavone 3,5,7-trihydroxy-6-methoxyflavone was isolated from leaf extracts of Chromolaena leivensis (Hieron), commonly named plant of cancer. It was identified based on their physicochemical propierties and spectroscopic data. This compound presented a methoxylation at C6, this is uncommon in flavonoids and which may confer some specificity of i...

To obtain a scientific basis and justification of plant domestication in the use of Ageratina gracilis, we did an in vitro study of the anticancer potential of extracts and fractions from its leaves and inflorescences. Firstly, cytotoxicity was evaluated against five human tumorigenic cell lines by MTT assay. Subsequently, the chloroformic fraction...

RESUMEN En este trabajo se analizó la producción del flavonoide 5,7-dihidroxi-3,7,8-trimetoxi flavona y del diterpeno ácido Kaur 9 (11) – 16-eno – 19 oico en hojas y flores durante las diferentes etapas de crecimiento de la especie Gnaphalium elegans, por medio de cromatografía de capa delgada de alta resolución (HPTLC). SUMMARY In this work was ev...