
Jean-Marie AnnoniUniversity of Fribourg · Neuroscience
Jean-Marie Annoni
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605
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Introduction
Additional affiliations
January 2011 - May 2023
January 2000 - October 2010
January 1992 - October 2010
Publications
Publications (605)
Background/Objectives: Although the embodiment of action-related language is well-established in the mother tongue (L1), less is known about the embodiment of a second language (L2) acquired later in life through formal instruction. We used the high temporal resolution of ERPs and topographic ERP analyses to compare embodiment in L1 and L2 and to i...
Objective: To determine the falsifiability of the proposed etiology of static mechanical allodynia (SMA) as a paradoxical painful touch-evoked slight tactile HYPO-aesthesia caused by Aβ axonal lesions in patients treated for Complex Regional Pain Syndrome (CRPS) of the foot.
Methods: This is a retrospective analysis of prospectively collected clini...
Individual differences in working memory and musical aptitude, as well as task complexity are crucial in predicting the performance of word stress perception in a second language (L2). The present study investigated the interactive effects of these factors with the listeners’ first language. French and German listeners, both without knowledge of Sp...
Introduction
Primary progressive aphasia (PPA) is a neurodegenerative syndrome that causes
speech and language decline1,2. The nonfluent variant (nfvPPA), typically associated
with predominant left posterior fronto-insular atrophy and underlying tau pathology, is
characterized by impaired syntax and/or motor speech. Previous studies have
demonstrat...
(1) Background: Bilingualism has been reported to shape the brain by inducing cortical changes in cortical and subcortical language and executive networks. Similar yet different to bilingualism, diglossia is common in Switzerland, where the German-speaking population switches between an everyday spoken Swiss German (CH-GER) dialect and the standard...
Objectives: Cognitive biases (CB), an important source of medical errors, have been investigated in many clinical specialties. They have never been demonstrated in the field of neurocognitive disorders and Alzheimer’s disease, where the diagnostic accuracy is complex, particularly regarding their differential diagnoses. This study aims to establish...
The present research examines the neural predisposition for L2 stress learning, and investigates whether this predisposition is driven by the learners' native language (free-vs. fixed-stressed). fMRI and behavioral experiments were run with French-and German-speaking listeners. Participants performed stress-related tasks in Spanish (an unknown lang...
Background
Patient and Public Involvement (PPI) in aphasia research requires researchers to include people with aphasia as research partners from the beginning of the study. Yet the quality of reporting on the level and type of involvement is poorly documented in the absence of a framework to guide PPI in aphasia research. This study aimed to extra...
Theories of embodied cognition postulate that language processing activates similar sensory-motor structures as when interacting with the environment. Only little is known about the neural substrate of embodiment in a foreign language (L2) as compared to the mother tongue (L1). In this fMRI study, we investigated embodiment of motor and non-motor a...
Smell and taste disorders are recognized as frequent, and often the only, signs occurring in the early phase of SARS-Cov-2 infection and in many cases perdure as post-viral symptoms. This evidence raised a general reconsideration of chemosensory deficits, further suggesting that their appearance can be considered as a discriminative and predictive...
Dementia is a global public health problem with increasing prevalence and incidence worldwide. The African continent is expected to bear the biggest brunt of the burden of dementia by 2050 because of the rapid demographic changes, including rapid population growth, an increase in life expectancy, and ageing. However, French-speaking Sub-Saharan Afr...
Objective: To examine existing evidence on the effect of bilingualism on cognitive outcomes in the stroke population.
Introduction: Stroke is associated with an increased risk of vascular cognitive impairment. Bilingualism promotes cognitive reserve and resilience through the effect of language switching on the cognitive control systems and is sugg...
Background: Patient and Public Involvement (PPI) in aphasia research obliges researchers to include people with aphasia (PWA) as research partners from the beginning of the study. Yet the quality of reporting on the level and type of involvement is poorly documented in the absence of a guideline to document contribution. This study aimed to extract...
Lexical stress is an essential element of prosody. Mastering this prosodic feature is challenging, especially in a free-stress foreign language for individuals native to a fixed-stress language, a phenomenon referred to as stress deafness. By using functional magnetic resonance imaging, we elucidated the neuronal underpinnings of stress processing...
Introduction
The paper examines the discrimination of lexical stress contrasts in a foreign language from a neural perspective. The aim of the study was to identify the areas associated with word stress processing (in comparison with vowel processing), when listeners of a fixed‐stress language have to process stress in a foreign free‐stress languag...
Lexical stress is an essential element of prosody. Mastering this prosodic feature is challenging, especially in a stress-free foreign language for individuals native to a stress-fixed language, a phenomenon referred to as stress deafness. By using functional magnetic resonance imaging, we elucidated the neuronal underpinnings of stress processing...
Research Objectives
To explore the views of people who live with chronic stroke and aphasia on their potential involvement as research partners.
Design
Qualitative study: semi-structured interviews. Participatory research model with a Patient and Public Involvement (PPI) partner: a person with chronic stroke-induced aphasia.
Setting
On line inter...
Background and aims: Porphyrias constitute a group of rare genetic diseases due to various, mostly autosomal dominant mutations, causing enzymatic deficiency in heme biosynthesis. As a result, neurotoxic porphyrin precursors and light-sensitive porphyrins accumulate, while dysfunction in their targets determines the disease symptoms. Variegate porp...
This scientific commentary refers to ‘Unclassified fluent variants of primary progressive aphasia: distinction from semantic and logopenic variants’ by Watanabe et al. (https://doi.org/10.1093/braincomms/fcac015)
The impact of aphasia on the everyday life of Greek-speaking people with aphasia (PWA) is often underestimated by rehabilitation clinicians. This study explores the adaptation and psychometric properties of the Greek (GR) version of The Aphasia Impact Questionnaire-21 (AIQ-21-GR) to address this issue. The aim of this study is to determine the reli...
Background:
Patient and Public Involvement (PPI) is the active partnership between researchers, patients and laypeople in the process of creating research. PPI in stroke aphasia research aims to ensure equal opportunities for informed decision-making and guarantee democratic representation of patient partners within the research team. Yet, little...
Primary progressive aphasia (PPA) is a neurodegenerative disorder with a progressive loss of language. Long-term support requires speech therapy but also individually set training programs. Here we propose an 8-month individualized speech-training program which alternates 3-week periods of transcranial direct current stimulation (tDCS) treatment wi...
This study aims to determine which factors within the first week after a first-ever transient ischemic attack (TIA) or minor ischemic stroke (MIS) are associated with stroke survivors' ability to return to either partial or full time paid external work (RTpW). In this single-center prospective cohort study, we recruited 88 patients with first-ever...
Mechanical allodynia is a hypersensitivity to touch affecting one-third of people living with neuropathic pain. One of its peculiarities is that the stimulation of the concerned territory can cause delayed pain. The objectives of this article are: 1) Inform clinicians about the existence of mechanical allodynia; 2) Describe the non-nociceptive stim...
Background:
Evidence-based assessments for people with aphasia (PWA) in Greek are predominantly impairment based. Functional communication (FC) is usually underreported and neglected by clinicians. This study explores the adaptation and psychometric testing of the Greek (GR) version of The Scenario Test. The test assesses the everyday FC of PWA in...
Service Organization/Quality Improvement and Patient-Centred Outcomes
Riassunto
Una lesione parziale dei nervi periferici può portare a fenomeni dolorosi neuropatici, associati a disturbi della sensibilità, come un’ipoestesia tattile o un’allodinia meccanica. Se non trattato, il dolore neuropatico può divenire cronico e influenzare la qualità di vita dei pazienti. La metodica di rieducazione sensitiva del dolore è un...
One of the strengths of the method of Somatosensory Pain Rehabilitation (SPR) is that it leads therapists to the management of sometimes, very complex neuropathic pain conditions with, at the start, a very simple question “either – or”. May the patient’s condition be a stage I of Aβ axonal lesions, stage IV with mechanical allodynia, or CRPS, may t...
Laughter and yawning can both occur spontaneously and are highly contagious forms of social behavior. When occurring contagiously, laughter and yawning are usually confounded with a social situation and it is difficult to determine to which degree the social situation or stimulus itself contribute to its contagion. While contagious yawning can be r...
Resumen
Las lesiones parciales de los nervios periféricos pueden dar lugar a síntomas de dolor neuropático, asociados a trastornos de la sensibilidad, como la hipoestesia táctil o la alodinia mecánica. Si no se trata, el dolor neuropático puede volverse crónico y afectar a la calidad de vida de los pacientes. El método de rehabilitación sensitiva d...
Background
Alzheimer’s disease (AD) remains to date an incurable disease with a long asymptomatic phase. Early diagnosis in peripheral biofluids has emerged as key for identifying subjects at risk and developing therapeutics and preventative approaches.
Objective
We apply proteomics discovery to identify salivary diagnostic biomarkers for AD, whic...
Introduction:
Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts.
Methods:
To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeho...
This review focuses on embodied semantic theories of language, which assume a concomitant activation of sensorimotor areas during verbal processing. Behavioural and functional studies showing the influence of semantic treatment on perceptuo- and sensori-motor cortices are here presented. We focus on embodiment of the second language (L2) in bilingu...
Background
Confusion and hallucinations in geriatric patients are frequent symptoms and typically associated with delirium, late-life psychosis or dementia syndromes. A far rarer but well-established differential in patients with rapid cognitive deterioration, acute psychosis, abnormal movements and seizures is autoimmune encephalitis. Exemplified...
Background Patient and Public Involvement (PPI) is the active partnership between researchers and patients. PPI in stroke aphasia research aims to ensure equal opportunities for informed decision-making and guarantee democratic representation in citizen control of PPI projects. Yet, little is known about the factors that hinder and/or promote the a...
Linguistic processes in the bilingual brain are partially shared across languages, and the degree of neural overlap between the languages is influenced by several factors, including the age of acquisition, relative language proficiency, and immersion. There is limited evidence on the role of linguistic distance on the performance of the language co...
The Memory Centres of several Swiss hospitals have set up a national online registry for Alzheimer's research, called www.BHR-suisse.org. This type of registry already exists in the United States (www.brainhealthregistry.org/) and the Netherlands (https://hersenonderzoek.nl/). It contributes, as do these initiating sites, to the creation of a globa...
Les centres de la mémoire de plusieurs hôpitaux suisses ont créé un Registre national suisse en ligne pour la recherche sur Alzheimer, intitulé www.bhr-suisse.org. Ce type de registre existe déjà aux États-Unis (www.brainhealthregistry.org/) et aux Pays-Bas (hersenonderzoek.nl/). Il contribue, au même titre que ces sites initiateurs, à constituer u...
Bilingual word recognition has been the focus of much empirical work, but research on potential modulating factors, such as individual differences in L2 exposure, are limited. This study represents a first attempt to determine the impact of L2-exposure on bilingual word recognition in both languages. To this end, highly fluent bilinguals were split...
Life is becoming possible
I move forward with difficulty. Each day, one step. Some steps are more difficult, others are hesitant, and even in the wrong direction. The path is long. Too long. The sensations are devastating and unbearable. The ground on which I walk, once covered with freshly mown grass, gives way to sharp, burning coals. My foot suf...
Status epilepticus is a feared complication in patients with epilepsy with a mortality rate of almost 10%. It is important to recognize this clinical entity quickly. A delay in diagnosis or treatment has significant consequences on mortality and morbidity. This article is a review of the current literature and aims to provide management of status e...
Background and aim: There is a large body of literature on the use of questionnaires to describe the impact of aphasia on stroke survivors’ quality of life (QOL). The findings demonstrate robust evidence for the severe effects of communication deficits on social integration and well-being for people with aphasia (PWA) post stroke. Traditionally, PW...
Une atteinte partielle des nerfs périphériques peut entraîner des phénomènes douloureux neuropathiques, associés à des troubles de la sensibilité, tels qu’une hypoesthésie tactile ou une allodynie mécanique. Si elles ne sont pas traitées, les douleurs neuropathiques peuvent devenir chroniques et affecter la qualité de vie des patient·e·s. La méthod...
BACKGROUND
Obsessive-compulsive disorder (OCD) is characterized by intrusive and irrational thoughts as well as repetitive behaviours. OCD-like behaviours have been described in a wide range of neurological disorders. In cerebrovascular accidents, the semiology arises mostly from lesions to the basal ganglia – though cortical regions may also be in...
Zusammenfassung. Psychotische Erkrankungen im Alter umfassen ein grosses Spektrum an Ursachen und Manifestationen. Häufig treten sie im Rahmen einer Depression, einer demenziellen Entwicklung, eines Substanz- und Medikamentenmissbrauchs oder eines Delirs auf. Während im Alter neue Erkrankungen auftreten können, erreichen zunehmend auch mehr Persone...
The present document represents the position of Swiss health-care associations, clinical and research centers, research-supporting foundations, and the association Alzheimer Switzerland regarding the care of persons with dementia and Alzheimer’s disease. We claim that dementia is not part of normal aging but a disease developing more frequently in...
Background
The COVID-19 pandemic has been associated with significant psychological and social distress worldwide. We investigated fear and depression among adults in Cameroon during different phases of the COVID-19 outbreak.
Methods
An online survey was conducted in Cameroon from June–December 2020 using a structured questionnaire. Socio-demograp...
According to embodied theories, motor and language processing bidirectionally interact: Motor activation modulates behavior in lexico-semantic tasks (semantic resonance), and understanding motor-related words entails activation of the corresponding motor brain areas (motor resonance). Whereas many studies investigated such interaction in the first...