Jean-François Uhl

Paris Descartes, CPSC | Paris 5 · UFR biological (Saints-Pères)

Virtual Reality has become an important educational tool, due to the pandemic and increasing globalization of education. This paper presents a framework for teaching Virtual Anatomy at the university level. Virtual classes have become a staple of today's curricula because of the isolation and quarantine requirements and the increased international...

Objective: To carry out a 3D vector reconstruction of the nerves of the ventral region of the neck from anatomical sections of the “Korean Visible Human” for educational purposes. Materials and Methods: The anatomical subject was a 33-year-old Korean man who died of leukemia. He was 164cm tall and weighed 55kgs. A cryomacrotome sectioned the frozen...

Objective: To carry out a 3D vector reconstruction of the nerves of the ventral region of the neck from anatomical sections of the “Korean Visible Human” for educational purposes. Materials and Methods: The anatomical subject was a 33-year-old Korean man who died of leukemia. He was 164cm tall and weighed 55kgs. A cryomacrotome sectioned the frozen...

Objective Fractures of the pelvis are serious pathologies that can be life-threatening. Surgical treatment of complex fractures is difficult, due to the proximity of neighboring vessels and organs. Our goal was to create a practical educational simulation model printed in 3 dimensions (3D) from CT scans images of a patient who had a complex fractur...

Computer-Assisted Anatomical Dissection (CAAD) is a new method of 3D reconstruction of anatomical structures from histological or anatomical slices. It uses staining and immunomarking of the tissues for a more precise identification, in particular for the nerves and the vessels, leading to an easy morphological segmentation. Starting from a digital...

As the oldest medical craft, anatomy remains the core and foundational field of medicine. That is why anatomy is in perpetual advancement, thanks to the technical progress in exploring the human body through computer science and biomedical research. Knowledge of the human body is the basis of medicine. Classical cadaver dissection, the standard dis...

Teaching morphological sciences’ suffers from the lack of human corpses for dissection due to ethical or religious issues, worsened by increasing students’ demand for educational anatomy. Fortunately, the technological revolution now put at our disposal new virtual reality tools to teach and learn anatomy. These multimedia tools are changing the wa...

Purpose Digital anatomy is a novel emerging discipline. Use of virtual reality brings a revolution in educational anatomy by improving retention and learning outcomes. Indeed, virtual dissection is a new learning tool for students and surgeons. Three-dimensional vectorial models of the human body can be created from anatomical slices obtained by le...

Background: Adjustable compression wraps are used for treating lymphedema and chronic venous insufficiency. These diseases often affect elderly patients with associated pathologies or other limiting factors. These can prevent the self-application of the device by patients on themselves. A better understanding of these factors or the associated pat...

Zusammenfassung Die Perforansvenen (PV) der unteren Extremitäten sind nicht nur gerade und direkte Verbindungen zwischen den tiefen und oberflächlichen Venennetzen, sondern bilden gemeinsam ein weit verzweigtes Netz. Trotz ihrer starken anatomischen Variabilität ist ihre Position bemerkenswert konstant und prognostizierbar. Dies ist durch ihre enge...

This book offers readers fresh insights on applying Extended Reality to Digital Anatomy, a novel emerging discipline. Indeed, the way professors teach anatomy in classrooms is changing rapidly as novel technology-based approaches become ever more accessible. Recent studies show that Virtual (VR), Augmented (AR), and Mixed-Reality (MR) can improve b...

Introduction Malignant bone tumors of the sternum are rare. Their surgical treatment remains largely based on precise knowledge of preoperative imaging in order to define appropriate margins during tumor resection. We provide a practical 3-dimensional (3D) modeling method to better understand the relationships between these tumors and neighboring o...

A must have book for anatomists, phlebologists, radiologists and surgeons Deep knowledge of venous anatomy illustrated with 618 color figures

Objective To assess the feasibility of 3D modelisation of fetal anatomy by using the Computer-assisted anatomic dissection (CAAD) based on immunolabeled histologic slices and MRI slices with a specific 3D software. Study design For pelvis and lower limbs, subjects came from legal abortion, medical pregnancy termination, or late miscarriage. Specim...

Objective The purpose of this comprehensive review is to give a historical account of iliac vein compression and to analyse the pathophysiological aspects and their clinical implications. Methods An extensive search of the databases was performed from inception until 2019. The patterns, length and site of compression, wall and luminal changes, and...

The CEAP (Clinical-Etiology-Anatomy-Pathophysiology) classification is an internationally accepted standard for describing patients with chronic venous disorders and it has been used for reporting clinical research findings in scientific journals. Developed in 1993, updated in 1996, and revised in 2004, CEAP is a classification system based on clin...

3D reconstruction from anatomical slices allows anatomists to create three dimensional depictions of real structures by tracing organs from sequences of cryosections. However, conventional user interfaces rely on single-user experiences and mouse-based input to create content for education or training purposes. In this work, we present Anatomy Stud...

APPORT DE L’ÉCHOGRAPHIE À L’IMAGERIE DES VAISSEAUX LYMPHATIQUES PAR RAPPORT AUX AUTRES MÉTHODES D Matter, E Grosshans, J Muller, C Furderer, C Mathelin, S Warter, JP Bellocq et C Maillot ABSTRACT RÉSUMÉ Sonographic imaging of lymphatic vessels compared to other methods This paper reviews for the first time the normal and abnormal appearances of lym...

Introduction: In surgical approaches to condylar fractures, there is a risk of damage to the transverse facial artery (TFA) which may in turn account for impaired blood supply to the temporomandibular joint (TMJ). In order to investigate the risk of damage to the TFA, and prevent lesions to this artery resulting from TMJ surgical procedures, we st...

Background The compliance to compression stockings in India is poor. One of the reasons is related to the inadequacy of sizing tables of compression stockings sold in India by western companies. Methods In 922 Indian patients, three circumference measurements of leg were taken in a standing position at different levels: Instep (level Y), Ankle (le...

Introduction: The aim of this study is to make an anatomical description of the bony venous perforators (PVs) at the knee level witch are frequently missed during investigation of patients with chronic venous disease. Material and methods: Multiple series of anatomical slices of fresh cadavers injected with green latex and series of CT venographies...

Introduction: The virtual dissection is a new and remarkable learning tool in anatomy. The authors present here a 3D reconstruction of the upper limb from the Visible Korean human slices. [1–4 Park HS, Choi DH, Park JS. Improved sectioned images and surface models of the whole female body. Int J Morphol. 2015;33(4):1323–1332. doi:10.4067/S0717-9502...

Introduction: “Adductor canal syndrome”, or “Jogger’s syndrome” has been described as an unusual cause of acute arterial occlusion in younger men. It is also been identified as a cause of compressive neuropathy of the saphenous nerve. Nevertheless, femoral vein compression in the canal has never been described. Our aim is to describe the anatomy an...

Introduction: Direct mechanical compression of the veins seems to be the main mechanism of action of compression therapy in venous disease. New imaging techniques allow a quantitative evaluation of the biophysical impact of compression on the 3D anatomy of the leg, particularly on the venous system The aim is to use 3D modeling and volume quantific...

Introduction: Our objective is to highlight the role of the semi-membranosus muscle, which is surprisingly not described in the major books of anatomy, as main thigh pump in the venous return [1 Uhl J.F, Gillot C. Anatomy of the veno-muscular pumps of the lowerlimbs. Phlebology. 2015;30(3):180–193. doi:10.1177/0268355513517686.[Crossref], [PubMed],...

Introduction: The development of digital research at the level of the anatomy laboratory with the vascular surgery unit by anatomo-radiological interpretation based on 2D segmentation and 3D reconstruction [1 Uhl JF, Chahim M, Cros F, A Ouchene - 3D modeling of the vascular system. Journal of Theoretical and Applied Vascular Research - JTAVR 2016;1...

Introduction: The aim of this work is to build a new educational tool to better understand venous anatomy of the lower limbs by the help of embryology, Duplex color assessment and 3d modeling by CT venography (CTV) Materials and methods: Pictures of anatomical drawings from the Atlas book of Gillot [1 Gillot C. Atlas book of the superficial veins o...

Introduction: Teaching of the morphological sciences suffers today from the lack of human corpses for dissection (due to ethic or religious issues), worsened by an increasing demand for educational anatomy. Fortunately, the technological revolution now put at our disposal educational tools to teach and learn anatomy: virtual dissection table, virtu...

Advanced venous anatomy Multimodality imaging: - anatomical disection - Dulex color investigation - CT venography HANS-ON SESSION with patients

Objectif Décrire la disposition anatomique des veines perforantes (VPs) du genou qui sont le plus souvent négligées ou ignorées lors des explorations des patients atteints de maladie veineuse chronique (MVC). Materiel et methodes De nombreuses séries de coupes anatomiques réalisées après injection de latex sur des cadavres frais, des explorations...

Background/aims: This study aims to describe the autonomic nervous network of the female pelvis with a 3D model and to provide a safe plane of dissection during radical hysterectomy for cervical cancer. Methods: Pelvises of 3 human female fetuses were studied by using the computer-assisted anatomic dissection. Results: The superior hypogastric...

Background: Prolonged immobility in the sitting position in the elderly is known to produce venous stasis with leg edema and possible skin changes. Methods: The authors have tested a treatment protocol in 30 patients to quantify the reduction of volume caused by an adjustable compression Velcro® wrap (Circaid Juxtalite®) after 15 days and to com...

Objectives The objective of the Vein Glossary was to develop a consensus document that defines commonly used terms in phlebology and gives them a precise and accurate understanding. Methods To achieve the goal, the three organizing physicians (M. Perrin, B. Eklöf, O. Maleti) first developed a list of terms used in the published literature and in p...

Introduction/Objectifs Réaliser une modélisation tridimensionnelle du foie chez le fœtus à partir de coupes IRM fœtales et d’un logiciel de reconstruction en 3D pour analyser la morphogenèse hépatique et celle du tronc porte. Matériels/patients et méthodes Les foies de 2 fœtus de 26 et 39 SA, indemnes de malformations, ont été modélisés à partir d...

Introduction/Objectifs Le but de cette étude était de décrire la topographie et la fréquence des différentes lésions d’endométriose pelvienne profonde. Matériels et méthodes Revue de littérature de 2003 à 2017 en utilisant les mots clés suivants : « anatomical distribution », « deeply infiltrating endometriosis », « deep endometriosis », « surgery...

Introduction/Objectifs Étudier la morphologie du cerveau et du tronc cérébral à l’aide d’un modèle 3D réalisé à partir de coupes d’IRM 3 Tesla de 3 fœtus indemnes de malformations encéphaliques et d’un logiciel de reconstruction 3D. Matériels/patients et méthodes Les cerveaux de 3 fœtus de 29 à 39 SA ont été reconstitués, à partir de coupes d’IRM...

MASTERCLASS OF MULTIMODALITY VENOUS IMAGING PARIS Descartes University 15-16th JUNE 2019 First announcement J.F UHL & M. LO VUOLO www.anatomy-masterclass.com

Background: Prolonged immobility in the sitting position in the elderly is known to produce venous stasis with leg edema and possible skin changes. Compression stockings are often applied for this clinical problem. There are few experienced nursing staff available to supervise the difficult task of stocking application. Methods: The authors have...

Objectif Contrairement à la fameuse pompe du mollet, les pompes musculaires de cuisse sont mal connues et jouent un rôle important dans le retour veineux du membre inférieur. Matériel et méthodes L’injection du système veineux de cadavres frais au Lalex suivie de la dissection anatomique de 300 membres inférieurs, des reconstructions 3D par scanne...

The embryogenesis of the venous network of the lower limbs explains the main variations of the venous network superficial veins, perforating veins, and deep venous system. It is likely that the number of the so-called primitive chronic venous disease could be explained by unknown underlying anatomical abnormalities [1].

The imaging is essential in vascular medicine for diagnosis and treatment. New imaging techniques since the advent of the spiral CT scan, invented by Hounsfield and Mac Cormack in 1972, brought us a revolution in whole medicine. This has been possible thanks to the development of new standards for imaging, particularly DICOM format. The aim of this...

Objectif Analyser le développement cérébral fœtal et de sa gyration à partir d’une modélisation vectorielle en 3D par dissection assistée par ordinateur à partir de coupes IRM du cerveau fœtal et d’un logiciel de reconstruction en 3D. Matériel et méthodes Les cerveaux normaux de 5 fœtus de 19 à 37 SA ont été reconstruits en 3D à partir de coupes I...

La litterature sur l’insuffisance veineuse prend tres peu en consideration les varices du pied au profit de la varicose jambiere malgre la plainte esthetique et les possibles complications thrombotiques. Souvent les varices du pied sont dependantes du reflux tronculaire sus-jascent. Mais parfois, l’examen minutieux revele l’absence de connexion a l...

Contexte La compliance est la clé de voûte de l’efficacité du traitement compressif. Cependant, l’auto-évaluation du patient lui-même est le seul moyen de l’évaluer ce qui n’est pas fiable. Plusieurs études ont montré une compliance très faible, de 30 à 50 % après 3 mois (Raju JVS 2004), mais à notre connaissance, la compliance réelle n’a jamais ét...

Cas clinique Madame Christine M, 75 ans, consulte pour douleurs, œdèmes et hypodermite des membres inférieurs. À l’examen, il existe des lésions multiples, godet, Stemmer positif, classé C5s. Dans ses antécédents, on note une HTA traitée par diurétique thiazidique, et des antécédents familiaux d’insuffisance veineuse. L’échographie Doppler artério-...

Objectives: To precise key-points of surgical neuroanatomy of the female pelvis to improve nerve-sparing radical hysterectomy (RH). Material and Methods: Review of the literature, computer-assisted anatomical dissection, and classic dissection of a female cadaver. Results: The superior hypogastric plexus (SHP) divides into two hypogastric nerves (H...

Background: The foot venous pump is located in the plantar veins, where both its anatomy and connections with the saphenous roots and the foot perforator veins are not well known, and therefore, they are underinvestigated in daily practice. The aim of this paper is to describe the unique anatomy and the functional role of the foot perforator veins...

The 3D modeling of the vascular system could be achieved in different ways: In the venous location, the morphological modeling by MSCT venography is used to image the venous system: this morphological modeling tool accurately investigates the 3D morphology of the venous network of our patients with chronic venous disease. It is also a fine educatio...

Background: Patient compliance is the cornerstone of compression therapy success. However, there has been up to now no tool to assess it other than self-reporting by the patient, which is not reliable. Material and methods: Forty active females classified C2S were enrolled to wear compression stockings (CS) providing a pressure of 15-20 mmHg at...

After a cure varicose veins, surgery, phlebectomy, sclerotherapy or other, judging oneself its own performance look easy. We always seem to have done well, the goal being the improvement of symptoms and signs, even their disappearance. The evaluation of our results can be: - by our own physical examination; - by other people, doctors or not; - by s...

Monsieur Jacques B., 75 ans, 175 cm, 86 kg, consulte son angiologue en urgence pour une douleur du membre inférieur gauche survenue au décours d’un voyage en avion de courte durée (3 h). Dans ses antécédents, on note une thrombose veineuse de la petite saphène gauche variqueuse en 2009, un stripping de la petite saphène gauche en 2010, une HTA depu...

Objectif Les PVVI forment un large reseau veineux continu, avalvule intrarachidien allant du sacrum jusqu’a l’endocrâne. Notre but est de demontrer leur role majeur comme voie de derivation en cas d’obstruction ilio-cave. Materiel et methodes Des reconstructions 3D par scanner helicoidal ou IRM apres injection du systeme veineux de 30 cadavres au l...

Objectives: To achieve a 3D vectorial model of a female pelvis by Computer-Assisted Anatomical Dissection and to assess educationnal and surgical applications. Materials and method: From the database of "visible female" of Visible Human Project(®) (VHP) of the "national library of medicine" NLM (United States), we used 739 transverse anatomical...

Nos connaissances portent principalement sur des mammifères en particulier le travail de Lewis (1906) sur le lapin. Mais on ne peut transposer ces données à l’humain et il n’existe aucune observation directe disponible. Objectif Décrire et analyser les premières étapes de l’embryogenèse veineuse des membres inférieurs. Méthodes La DAAO permet de...

Objet Réaliser une reconstruction 3D vectorielle du pelvis féminin à partir de coupes anatomiques dans un but essentiellement pédagogique. Méthodes Nous avons utilisé la base de données du Korean visible human. Neuf cent trente-deux coupes anatomiques de 0,33 mm 2523 à 3455 ont été utilisées sur les 8508 coupes du corps entier. La segmentation man...

Objectifs Réaliser une modélisation 3D de l’os coxal de l’homme à partir des coupes de Visible Human afin d’améliorer la compréhension de cet os de la part des étudiants. Matériel et méthodes Deux cent dix-neuf coupes du dataset de VisHum de 1732 à 1951. Le logiciel WINSURF est utilisé pour réaliser le contourage et la modélisation 3D. Résultats...

Objet Réaliser une reconstruction 3D vectorielle du pelvis féminin à partir de coupes anatomiques dans un but essentiellement pédagogique. Méthodes Nous avons utilisé la base de données de « visible female » du Visible Human Project® (VHP) de la « national library of medicine » NLM (États-Unis). 750 coupes anatomiques de 0,33 mm d’épaisseur allant...

Introduction La technique de la DAAO a été décrite en premier par Yucel et Baskin [1]. Nous l’avons implémentée dans une série de travaux sur les nerfs du pelvis réalisés en collaboration avec l’université Paris 13 [1–3]. La faisabilité de cette technique a été également démontrée pour étudier les stades de l’embryogenèse veineuse [4]. Objectif Ré...

Introduction Le territoire distal du membre inférieur par l’arcade dorso-plantaire est vascularisé dans la majorité des cas par les artères tibiales antérieure et postérieure. Objet Montrer que dans de rares cas (5 %) l’artère fibulaire participe à cette vascularisation distale. Démontrer que ces variations anatomiques sont explicables par l’embry...

Introduction Les veines perforantes (VP) du pied ont un mode de fonctionnement unique : contrairement à toutes les autres VP du membre inférieur, elles drainent le sang des veines profondes (veines plantaires) vers le réseau superficiel. Objet Décrire l’anatomie des VP du pied qui sont des voies de drainage vers le réseau saphène lors de la systol...

Embryogenesis of the venous system is a complex phenomenon that is not fully understood. In spite of the studies done by Born, Hochstetter, and Lewis, we do not know the precise chain of events leading to vasculogenesis of the venous network in humans. Yet, this is an important topic in order to improve our anatomical knowledge, which is of the hig...

To describe the anatomy of the lymph node venous networks of the groin and their assessment by ultrasonography. Anatomical dissection of 400 limbs in 200 fresh cadavers following latex injection as well as analysis of 100 CT venograms. Routine ultrasound examinations were done in patients with chronic venous disease. Lymph node venous networks were...

Les nécroses cutanées sont des complications rares des traitements anticoagulants oraux par antivitamine K (AVK). Elles surviennent approximativement chez 1 patient sur 1000 à 10 000 patients. Cette réaction survient classiquement chez des patients chez qui l’anticoagulation a été trop forte au départ. Les lésions sont précédées de paresthésies, de...

Introduction Les veines perforantes (VP) du pied ont un mode de fonctionnement unique : contrairement à toutes les autres VP du membre inférieur, elles drainent le sang des veines profondes (veines plantaires) vers le réseau superficiel. Objectif Décrire l’anatomie des VP du pied qui sont des voies de drainage vers le réseau saphène lors de la sys...

Objectif Décrire et illustrer en anatomie 3D un cas clinique de malformation veineuse congénitale, la veine marginale persistante (VMP). Matériel et méthodes Homme de 29 ans, présentant de volumineuses varices douloureuses du bord externe de la jambe et du pied droits, avec dilatation d’un volumineux tronc tubulaire de 9 mm de la face postéro-laté...

Objective: To study of the microcirculatory effects of elastic compression stockings. Materials and methods: In phlebology, laser Doppler techniques (flux or imaging) are widely used to investigate cutaneous microcirculation. It is a method used to explore microcirculation by detecting blood flow in skin capillaries. Flux and imaging instruments...

Background: The "Adductor canal syndrome" has been described as an unusual cause of acute arterial occlusion inside the Hunter's canal in young sportsmen. It may also produce a compressive neuropathy of the saphenous nerve. To our knowledge, femoral vein compression in the canal has never been reported. Objective: To describe the anatomy, to pro...