Jean-François Huon

Jean-François Huon
University of Nantes | UNIV Nantes · UFR des Sciences Pharmaceutiques et Biologiques

PharmD, PhD

About

49
Publications
3,630
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84
Citations

Publications

Publications (49)
Article
Full-text available
Purpose The aim of this study was to explore the beliefs, perceptions and representations of patients in order to identify the determinants of oral anticancer drugs adherence and to take action in current practice to improve patient support in digestive oncology. Methods We constructed a semi-directed interview guide which aimed to explore the pat...
Article
Echinocandins are noncompetitive inhibitors of the GSC1 subunit of the enzymatic complex involved in synthesis of 1,3-beta-D-glucan, a cell wall component of most fungi, including Pneumocystis spp. Echinocandins are widely used for treating systemic candidiasis and rarely used for treating Pneumocystis pneumonia. Consequently, data on P. jirovecii...
Article
Objectives This multicenter study aimed to assess the performances of gradient diffusion (GD) method in comparison to broth microdilution (BMD) method for susceptibility testing of dalbavancin, daptomycin, vancomycin, and teicoplanin. Methods Minimum Inhibitory Concentrations (MICs) were retrospectively determined concomitantly by BMD and GD metho...
Article
Résumé Introduction–objectifs La pharmacie clinique se développe en France depuis une décennie. Cependant, l’intégration du pharmacien clinicien au sein de l’équipe médico-soignante dans le service de chirurgie est encore à ses balbutiements, tandis que son positionnement dans le parcours chirurgical est insuffisamment défini. Le groupe de travail...
Article
Full-text available
Diabetes is marked by a range of complications, including chronic infections that can lead to limb amputation. The treatment of infected wounds is disrupted by arteriopathies that reduce tissue perfusion as well as by the critical development of bacterial resistance. We evaluated the impact of a local application of bacteriophages compared to that...
Article
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Background The pathogenic and oncogenic roles of papillomavirus (HPV) infections have been documented and shown to occur in women as well as in men. While other countries have already extended their vaccination guidelines to include boys, in 2019 the French National Authority for Health validated implementation of HPV vaccination in the 2020 vaccin...
Article
Résumé Position du problème Si le rapport bénéfice risque clairement favorable de la vaccination est depuis longtemps démontré, la méfiance de la population à l’égard des vaccins, elle, est croissante et la couverture vaccinale perfectible. La question se pose alors de rechercher des moyens concrets pour l’améliorer. Nous avons interviewé des prof...
Article
Complications with bilateral sagittal split osteotomy (BSSO) can sometimes result from surgical inexperience. Our aim was to present a 3-dimensional printed mandibular model for BSSO training in a maxillofacial surgical education programme. A polymethacrylate mandibular model obtained from mandibular cone-beam computed tomographic (CT) images was d...
Article
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Résumé L’évolution de la prise en charge des patients a conduit le pharmacien à changer de posture et se rendre au plus près du patient. Afin d’assurer au mieux cette prise en charge, plusieurs dispositifs éducatifs et d’accompagnement sont apparus. « Conseils », « consultations » et «entretiens pharmaceutiques », « bilan de médication partagé » ou...
Article
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Résumé Objectifs: L’impact économique du Patient blood management (PBM) doit être évalué au-delà du seul coût d’acquisition des produits sanguins. L’estimation des coûts indirects peut varier selon les organisations et les éléments pris en compte. La transposition des données de la littérature dans un contexte local spécifique s’avère ainsi délicat...
Article
Phytotherapy is the main complementary medicine for which patients afflicted with cancer have recourse but the associated consumption of phytotherapy products gives rise to a risk of interaction with anticancer agents. The aim of this prospective study was to measure the prevalence of the consumption of phytotherapy products as well as their intera...
Article
Purpose Fibrous dysplasia (FD) is a benign fibro-osseous developmental disorder of growing bone, sometimes involving the craniofacial skeleton (CFD). We wish to present a patient series with CFD of the orbital region and discuss treatment modalities. Methods Twelve patients were referred for orbital CFD in the Nantes University Hospital between 20...
Article
Résumé Position du problème : En France, de nombreux parents perdent confiance en la vaccination, ce qui impacte directement la couverture vaccinale. Les pharmaciens d’officine, comme les autres professionnels de santé, sont souvent confrontés à des parents montrant une défiance vaccinale. Méthodes: A l’aide d’une enquête diffusée dans une école et...
Article
Full-text available
Diabetic wound infection is a frequent complication that may result in limb amputation. To develop new treatment strategies in response to increasing bacterial resistance, animal models are needed. We created a diabetic mouse model with chronically infected wounds. Diabetes was induced using streptozotocin, and wounds were performed using a biopsy...
Conference Paper
Full-text available
Background and importance Since 2011, the French drug agency has sponsored an expanded access programme to make Malacef (artesunate) available for the treatment of severe malaria. This drug has not yet been approved by European and US pharmaceutical agencies, while it is available in China and several African countries. Aim and objectives The aim...
Conference Paper
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Background and importance Since 2015, a pharmacist/resident duo has been conducting drug reconciliation and medication review in the orthopaedic surgery department. They participate in multidisciplinary team (MDT) meetings to discuss patient with osteomyelitis. These clinical case conferences take place every week to determine the most suitable sur...
Conference Paper
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Background and importance Following the computerisation of prescriptions in the plastic surgery department of our hospital, some protocols have been modified, leading to an increase in iron supplementation (IS) prescriptions by anaesthetists in postoperative care. Aim and objectives The aim of our study was to perform an inventory of iron prescrip...
Conference Paper
Background and importance There are few data on the use of herbal medicines and the potential risks of herbal drug interactions (HDI) with oral anticancer drugs (OACD), even though their consumption is increasing. Aim and objectives The aim of this study was to collect data on consumption of medicinal plants by patients on OACD and to assess the p...
Article
Objectives: Numerous adverse drug events (ADEs) are not identified by doctors in medical emergencies, and they are a barrier to optimal treatment of patients. Identification of the factors that influence awareness of ADEs by doctors could allow events that compromise patient safety to be avoided. The aims of this study were to quantify the recogni...
Article
BACKGROUND: In France, many parents have lost confidence in vaccinations, which has a direct impact on immunization coverage. Pharmacists, like other health professionals, often encounter parents exhibiting vaccine distrust. METHODS: Using a survey distributed in a school and in a number of volunteering pharmacies, the objective of this study was t...
Article
Pressure therapy (PT) is commonly used to manage hypertrophic scars. It is often based on the use of elastic pressure garments, which are poorly suited for a facial localization. We describe the conception, fabrication, and use of a custom-made PT facial mask for primary prevention of hypertrophic scarring of complex facial wounds. The main advanta...
Article
Résumé L’entretien pharmaceutique est un moment d’échange privilégié entre le patient et son pharmacien, à l’officine ou en établissement de santé, durant lequel le pharmacien recueille des informations, conseille le patient, émet des messages d’éducation et de prévention. Selon l’étape du parcours de soins du patient, cet entretien n’a pas les mêm...
Article
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This study aimed to assess patient investigational medication knowledge and to identify factors associated with medication understanding by adult outpatients included in clinical trials. A cross-sectional prospectively designed survey was conducted on consecutive volunteers at 21 university teaching hospitals (in France) from February to December 2...
Article
Objective: Staphylococcusaureus is involved in around 20% of nosocomial pneumonia cases. Vancomycin used to be the reference antibiotic in this indication, but new molecules have been commercialized, such as linezolid. Previous studies comparing vancomycin and linezolid were based on models. Comparing their real costs from a hospital perspective w...
Article
Introduction En France, le vaccin contre le HPV est recommandé chez les jeunes filles de 11 à 19 ans et chez les hommes ayant des relations sexuelles avec des hommes (HSH), jusqu’à l’âge de 26 ans. La généralisation de la vaccination chez les jeunes garçons permettrait de protéger aussi les HSH avant l’infection et d’induire une immunité de groupe,...
Conference Paper
Full-text available
Background Invasive fungal infections (IFI) have a substantial morbidity and mortality, and their incidence has steadily increased over the past 20 years due to the increase in immunocompromised patients. The complex medical care, the expensive treatments and the emergence of antifungal resistance require appropriate prescribing. Purpose The aim o...
Conference Paper
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Background Like other cancerous diseases, there are now many oral treatments for haematological malignancies. These oral products have a lot of advantages, but their effectiveness depends on patient compliance. Do they have a good effect? Purpose This study aimed to assess patient medication compliance for myeloma oral treatments (Imids: Thalidomi...
Conference Paper
Full-text available
Background In the paediatric surgery unit (38 beds), due to the multiplicity of prescribers (anaesthetists and surgeons) and to the parents’ presence who are accustomed to looking after their child’s medications, the management of patients’ home medications is a critical point. The two main specialties of the unit are orthopaedic and visceral surge...
Article
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The treatment of cancer in elderly patients is complex and requires multi professional collaboration. Objectives: The aim of the study is to do an assessment of oral chemotherapy treatment information pathway between healthcare professionals. The objective is to propose measures to improve and strengthen the link betweenliberal and hospital healthc...
Article
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Introduction Les carbapénèmes sont des antibiotiques de dernier recours utilisés pour traiter des infections à bactéries multi-résistantes, comme les entérobactéries productrices de β-lactamases à spectre étendu (BLSE). Afin de préserver l’efficacité de ces antibiotiques, leur utilisation doit être encadrée. Une évaluation des pratiques professionn...
Article
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Multiple myeloma is a cancer that is considered to be a chronic disease today, due to novel therapies prolonging survival. It is therefore necessary to formally define the content of therapeutic education programs. The French Association of Multiple Myeloma Patients produced a competency framework for multiple myeloma patients and created tools hel...
Article
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Iatrogenic effects represent a large part of emergency admissions among elderly people. Throughout the care pathway of a patient, whether he is at home or hospitalized, many different health professionals are involved regarding the patient's medication. Medication reconciliation is one way to prevent adverse drug events at all care transitions for...
Article
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Background In France the most recent data on drug use by the elderly living at home were published in 2000. Since then the available drugs and their use have changed. Objective We compared data collected in 2011 with the 2000 data to evaluate how drug use has changed in France. Methods The study analysed retrospectively the 2011 data collected pros...
Article
We had for aim to assess antibiotic consumption and to better understand their use in nursing homes so as to target messages on relevant practice procedures sent to prescribers. The MedQual network asked nursing homes with in-house pharmacies to participate in a retrospective collection of yearly antibiotic consumption data with an Excel(®) spread...
Article
Full-text available
Background In France, inpatients receive prescribed drugs necessarily from hospital pharmacy. Since all medications are not available at the hospital pharmacy, drugs are substituted. Therefore, some patients bring their own outpatient medications despite the regulation. Objective The objective is to study the frequency and circumstances of use of...

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