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Golestan University of Medical Sciences | GOUMS · Journal of Clinical and Basic Research

Journal of Clinical and Basic Research

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35
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Publications (35)
Article
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Background: Testicular regression syndrome (TRS) is defined as the partial or total absence of testicular tissue in 46XY patients with normal external genitalia. The incidence of TRS has been reported to be less than 5% in patients with cryptorchidism. Herein, we report a case of a one-year old boy who underwent surgical exploration with an initial...
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The Olfactory bulb is a crucial structure involved in olfaction that is located in the ventral anterior of the forebrain. Due to physiological and anatomical connection between olfactory and emotion processing networks, olfactory dysfunction is seen in some psychiatric disorders. Strong evidences suggest that olfactory bulb volume can mirror olfact...
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Background and objectives: Breast cancer is one of the most common types of cancer in women. According to studies, cancer patients who hope to live longer will live longer. Living hope relies on life satisfaction in general as well as on marital satisfaction and social support. The aim of the present study was to investigate the relationship betwee...
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Background and objectives: Hemorrhage is the most common complication of tonsillectomy. However, the incidence of post-tonsillectomy hemorrhage may be affected by various factors including weight, age, medications, surgical technique, etc. This study was carried out to determine prevalence of post-tonsillectomy hemorrhage in patients undergoing ton...
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The clinical outcome of coronavirus disease 2019 (COVID-19) varies considerably from one individual to another and severe illness occurs only in a minority of cases. Evidence supports the role of genetic background alongside host, viral and environmental factors for COVID-19 severity. It seems that host genetic background affects the balance of imm...
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Background: Assessing patient satisfaction with community clinic (CC) services can contribute to promotion of quality of care. This study aimed to investigate the satisfaction level of patients with CC services and to identify the influential determinants of patient satisfaction in a rural area of Bangladesh. Methods: A cross-sectional study using...
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The most important aspect of cancer treatment is early diagnosis. The best serum marker currently available for diagnosis of prostate cancer (CaP) is serum prostate-specific antigen (PSA). However, PSA test does not have high specificity and is not reliable for differentiating benign prostate hyperplasia, non-aggressive CaP and aggressive CaP. In t...
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Background and objectives: Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to defects in insulin secretion or action. One of the consequences of diabetes is depression, which itself is related to complication of diabetes. Given the lack of enough studies on the relationship between psychological variables of parents and...
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Background and objectives: Educational appraisal plays a pivotal role in determining and promoting the educational quality and ensuring its continuous improvement. The performance of faculty members, characterized as the major building blocks of universities, makes significant contribution to the output of an educational system. Thus, the current s...
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Background and objectives: Despite advances in prenatal care, there is a high rate of morbidity and mortality in infants of diabetic mothers. Interventricular septal hypertrophy is a well-known congenital heart abnormality in neonates of mothers with gestational diabetes. In this study, we investigate the effect of gestational diabetes mellitus on...
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Background and objectives: Bladder filling and severe urgency to urinate may affect the cardiovascular system through viscero-visceral reflexes. In the cardiovascular system, post-micturition syncope is a well-known and clinically important consequence of this phenomenon. Despite the importance of such reflexes, limited numbers of studies have inve...
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Background and objectives: Pre-hospital emergency medical services (EMS) personnel are responsible for transferring patients. In case of improper patient handling, these individuals become vulnerable to various musculoskeletal problems including back pain. In this study, we aimed to evaluate the impact of an eight-hour training intervention about p...
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Since their discovery, non-coding RNAs have been known as key regulators of gene expression. Gaining a better understanding about their biogenesis and function may provide valuable knowledge about the heterogeneity of malignancies and contribute to identification of diagnostic, prognostic and therapeutic targets. Long non-coding RNAs (lncRNAs) are...
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Background and objectives: Pregnancy is one of the most important and stressful periods of women's lives. Recent studies have indicated an increasing trend in caesarean section rates. Although women are becoming more impatient and less resilient about vaginal delivery, raising awareness on stress management and resilience increases women's readines...
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Background and objectives: Obesity has become a global epidemic. Previous studies have reported a relationship between obesity in adults and socioeconomic factors, but the results regarding such relationship in the case of childhood obesity have been inconsistent. Therefore, this study aimed to determine the relationship between socioeconomic inequ...
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Background: HELLP syndrome is a multisystemic disorder characterized by elevated liver enzymes, hemolysis and low platelet count. If left untreated, it is associated with high risk of maternal and fetal mortality. It usually occurs in the third trimester of pregnancy but may sometimes occur after pregnancy. Herein, we report a patient with postpart...
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Background: Systemic lupus erythematosus (SLE) is a multi-systemic inflammatory disease that mainly affects women of childbearing age. Development of SLE during pregnancy increases the risk of some maternal and fetal complications. We herein present a pregnant woman with new-onset SLE during pregnancy. Case description: A 30-year-old pregnant woman...
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Background: Delayed postpartum hemorrhage is a midwifery emergency that occurs following vaginal or cesarean delivery. It is one of the leading causes of postpartum hysterectomy and maternal death. The condition may be caused by dehiscence of uterus incision after cesarean section, which can lead to severe and fatal bleeding. We herein report a cas...
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Backgrounds and objectives: Esophageal squamous cell carcinoma (ESCC) is a prevalent subtype of esophageal cancer in certain areas of the world. Molecular evaluations can provide a better understanding of the disease that could contribute to earlier diagnosis and treatment. Amplification or absence of microRNA (miRNA) genes has been described in ma...
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Background and objectives: One of the adverse effects of prone positioning in spine surgery is the occurrence of skin damage. Due to the high rate of spine surgeries and the frequent use of prone positioning during these procedures, we aimed to investigate postoperative skin complications after spine surgery in the prone position. Methods: This des...
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Background and objectives: Aging and its consequences are one of the major demographic issues in the world. The aim of this study was to determine quality of life and some related factors in elderly people living in Turkmen County (Iran) in 2017. Methods: This cross-sectional, descriptive-analytic study was conducted on 300 elderly people aged 60 y...
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Background and objectives: Anxiety is one of the most common psychiatric disorders that can cause functional impairment, which necessitates development of novel diagnostic and therapeutic methods. The aim of this study was to compare the effectiveness of cognitive-behavioral therapy and neurofeedback in reducing symptoms of anxiety. Methods: This w...
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Background and objectives: Liver and esophageal cancers are common among the Iranian population. This study aims to explore the common up-regulated genes in liver and esophageal cancer tissues using expressed sequence tags (ESTs) and to identify the role of key genes in cancer development. Methods: EST profiles of protein-coding genes in normal and...
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Background and objectives: Drug poisoning is a serious global health problem that sometimes requires hospitalization and intensive care. This study investigates clinical and demographic profile of acute poisoning cases admitted to the intensive care unit (ICU) of 5 Azar hospital in Gorgan, Iran. Methods: This cross-sectional descriptive study was c...
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Background and objectives: Breast cancer is the most common type of cancer and the second leading cause of cancer death in women aged 35-54 years. Belief in God and spiritual experiences can help the patients endure physical pain and enhance their physical and mental well-being. The purpose of this study was to compare spiritual experiences and hop...
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Background and objectives: Promoting and influencing the formation of professional behavior is one of the most challenging issues in education. The purpose of this study was to compare effects of context-based learning (CBL) and cooperative learning on professional behavior and critical thinking of anesthesiology students. Methods: This was a semi-...
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Background and objectives: Patient safety culture is one of the basic principles of health care. Nurses are the first to be involved in the implementation of this culture in clinical settings. The aim of this study was to determine effect of in-person and E-training on patient safety culture of nurse managers working in hospitals affiliated to the...
Article
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Background: Delayed hyponatremia is a common phenomenon following transsphenoidal surgery. Recent evidence suggests that the risk of developing intensive care unit-acquired hyponatremia is high following cardiac surgery. Herein, we report management of persistent hyponatremia after off-pump coronary artery bypass in a patient with diabetes and hypo...
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Background and objectives: Patients with thalassemia are at high risk of hepatitis B, hepatitis C, HIV infections because of the frequent and long-term need for blood transfusion. In the present study, we aimed to determine prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV in patients with thalassemia major in a hospital in Zah...
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Background and objectives: The developing process is necessary for converting a latent image into a visible image in conventional dental x-ray films. Despite the considerable advances made in development of radiographic equipment, there are also still some unresolved issues in this field. New self-developing film is an alternative to manual process...
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Background and objectives: Despite the importance of physiological changes that occur in the aging process, monitoring the nutritional status of the elderly has been neglected in developing countries. Nutrition has a significant impact on the quality of life and risk of morbidity and mortality among the elderly. In this study, we evaluated nutritio...
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Background and objectives: Diabetes is one of the main causes of morbidity and mortality worldwide. Spiritual experiences and religious belief can reduce tension and improve physical and mental health in diabetic patients. The purpose of this study was to compare spiritual experiences and distress tolerance between women with type 2 diabetes and he...
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Background and objectives: Diabetes mellitus is a major public health issue worldwide. Poorly managed type 1 and type 2 diabetics are at risk of developing several complications, including cardiovascular disease. Therefore, monitoring lipid profile and glycemic control in such patients are of great importance for reducing the risk of developing dia...
Article
Full-text available
Background and objectives: Patient safety culture is one of the basic principles of health care. Nurses are the first to be involved in the implementation of this culture in clinical settings. The aim of this study was to determine effect of in-person and E-training on patient safety culture of nurse managers working in hospitals affiliated to the...
Article
Full-text available
Background and objectives: Atopic dermatitis is a chronic inflammatory allergic disease that specifically affects the skin. The incidence of this disease is influenced by genetic and physical stimuli, hormones, stress and food and inhalant allergens. Given the increasing prevalence of atopic dermatitis, it is important to identify food and inhalant...

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