Javier Garcia-Alba

Complutense University of Madrid | UCM · Department of Evolutionary and Educational Psychology

The aim of this study is to adapt and validate the global deterioration scale (GDS) for the systematic tracking of Alzheimer’s disease (AD) progression in a population with Down syndrome (DS). A retrospective dual-center cohort study was conducted with 83 participants with DS (46.65 ± 5.08 years) who formed the primary diagnosis (PD) group: cogniti...

Background Down syndrome (DS) is considered the most frequent cause of early-onset Alzheimer’s disease (AD), and the typical pathophysiological signs are present in almost all individuals with DS by the age of 40. Despite of this evidence, the investigation on the pre-dementia stages in DS is scarce. In the present study we analyzed the complexity...

In this study, we examined normative data and diagnostic accuracy of a pictorial screening test to detect memory impairment for mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in Spanish-speaking adults with intellectual disability (ID). A total of 94 volunteers with ID (60 controls, 17 MCI, and 17 AD), were evaluated by neuropsycholog...

Background Despite presenting higher risk of dementia, mild cognitive impairment (MCI) is not well defined in Down syndrome population. Objective We aimed to describe cognitive and neuropsychological patterns associated with MCI in Down syndrome individuals. Method Two groups of adults with Down syndrome (control and prodromal) were studied throu...

Introduction: The majority of individuals with Down syndrome (DS) show signs of Alzheimer's disease (AD) neuropathology in their fourth decade. However, there is a lack of specific markers for characterizing the disease stages while considering this population's differential features. Methods: Forty-one DS individuals participated in the study a...

Introduction: This pilot study analyzes the effect of a cognitive training program in adults with intellectual disability (ID). Method: Twenty subjects (mean age 52.7 ± 9.77 years) with mild and moderate ID were divided in control and experimental group. Only the experimental group received the training program. This program was applied through the...

Introduction The Health of the Nation Outcome Scales for People with Learning Disabilities (HoNOS-LD) is a brief instrument that assesses functioning in people with intellectual development disorder and mental health problems/behaviour disorders. The aim of the present study was to examine the evidence on the validity of the scores based on the Spa...

Background We longitudinally assessed Down syndrome individuals at the age of risk of developing dementia to measure changes in brain anatomy and their relationship to cognitive impairment progression. Methods Forty-two Down syndrome individuals were initially included, of whom 27 (mean age 46.8 years) were evaluable on the basis of completing the...

Despite how important it is to assess executive functioning in persons with Intellectual Disability (ID), instruments adapted and validated for this population are scarce. This study’s primary goal was to find evidence for the validity of the ID version of the Tower of London (TOL DXtm ) test in persons with mild (ID Mi ) and moderate (ID Mo ) leve...

Introduction: Neuropsychological assessment in individuals with intellectual disability is of utmost importance in order to determine the cognitive deficits underlying brain dysfunction and limiting intellectual functioning and adaptive behavior. However, no neuropsychological batteries in Spanish language have been created and validated for this...

Background: Neural tissue alterations in Down syndrome are fully expressed at relatively late developmental stages. In addition, there is an early presence of neurodegenerative changes in the late life stages. Objective: The aims of this study were both to characterize white matter abnormalities in the brain of adult Down syndrome patients using...

Introduction: The Health of the Nation Outcome Scales for People with Learning Disabilities (HoNOS-LD) is a brief instrument that assesses functioning in people with intellectual development disorder and mental health problems/behaviour disorders. The aim of the present study was to examine the evidence on the validity of the scores based on the S...

UNIVERSITY STUDENTS REMEMBERING ATTACHMENT PATTERNS LEARNED THROUGH ROLE PLAYINGThis paper forms part of the studies for the improvement of the teaching-learning processes. The main aim is to observe the memory retention level of university students when asked about attachment and attachment patterns, which were explained through simulations and ro...

Introduction: Dementia caused by Alzheimer's disease commonly affects the adult population with Down's syndrome. This population presents two characteristic clinical features: a semiologic pattern that differs from the typical Alzheimer's disease, and previous intellectual deficits that may confound the clinical diagnosis. There is a clear need to...

Down syndrome (DS) they are practically non-existent studies that have valued the changes hemodynacs interhemispherical with Transcranial Doppler (TCD). To study changes mean velocity (MV) of the middle cerebral arteries (MCA) of both hemispheres during tasks of linguistic activation in people with DS. 10 subjects with DS and 10 subjects control. T...

Esta investigación analiza la imagen corporal y el riesgo de padecer trastornos de la conducta alimentaria en un grupo de estudiantes universitarios españoles (n=563), mediante la aplicación de dos cuestionarios: el EDI-3-RF y el IMAGEN. Los resultados muestran una proporción elevada de universitarios que se encuentran en riesgo de padecer un trast...

It is well known that Down syndrome (DS) is associated to neuropsycological deficits. However, less is known about their evolution from childhood to adulthood and the neuropsychological differences between the masculine and feminine sex. To study differences in the neurophycological state in DS in two different age groups between boys and girls. We...

niños con síndrome de Down Battery-ECODI. Battery of cognitive evaluation for persons with mental disability. Proposal of a new instrument to evaluate cognitive function of persons with Down syndrome Abstract: The aim of this study article is to present the guidelines followed for production of the Battery-ECODI (Battery of cognitive evaluation for...

Resumen La presente investigación se centra en la identificación de tipologías de personalidad eficaz en niños y adolescentes de altas capacidades, con el objeto de facilitar una posterior intervención psicoeducativa. La muestra está formada por un total de 34 niños y 20 adolescentes de la Asociación de Padres de Alumnos de Altas Capacidades del Pr...