Javed Ahamad

Javed Ahamad
Tishk International University, Erbil Iraq · Pharmacy

PhD Pharmacognosy & Phytochemistry
Javed Ahamad currently works as Assistant Professor at the Department of Pharmacy, Tishk International University

About

115
Publications
62,228
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738
Citations
Citations since 2017
85 Research Items
645 Citations
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2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
Introduction
Javed Ahamad currently works as Assistant Professor at the Department of Pharmacy, Tishk International University. Javed does research in Pharmacognosy and Phytochemistry. He is currently working on phyto-pharmacology of Kurdish plants.
Additional affiliations
September 2018 - present
Tishk International University
Position
  • Professor (Assistant)
October 2015 - June 2018
Mettu University
Position
  • Professor (Assistant)
June 2011 - August 2012
Jamia Hamdard University
Position
  • Senior Researcher
Education
June 2011 - March 2015

Publications

Publications (115)
Article
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Despite considerable studies, thrombocytopenia is still affecting millions of people with an increasing rate of morbidity and mortality around the globe. Therefore, we aimed to identify pharmacologically active polyphenolic compounds such as quercetin, apigenin and kaempferol in Psidium guajava for the management of thrombocytopenia using network p...
Article
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Piperine, known for its vast biological profile, is obtained from black pepper (Piper nigrum, Family: Piperaceae) which is one of the most commonly used spice in major parts of the world and is known for its pungent taste. Piperine is also found to act as an important bioenhancer by increasing the bioavailability of drug molecules and reducing thei...
Article
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Hemidesmus indicus (Apocynaceae) has been utilized traditionally in the Indian subcontinent for the treatment of snakebites and scorpion stings. It has also several beneficial bioactivities in human beings such as antidiabetic, anti-inflammatory and skin diseases. The purpose of this study was to assess the anti-venom capability of Hemidesmus indic...
Article
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Olea europaea Linn. (Olive; Oleaceae) commonly known as Zaytoon in the Mediterranean region. Olive oil and fruits are an important component of the Mediterranean diet as cooking oil and as a salad. Adulteration in Olive oil is very common with cheap edible oils. Thorough literature shows that there is no study conducted to check adulteration in Oli...
Article
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Lavandula angustifolia Linn. (Lavender) is an important source of high-quality fragrance and possesses several pharmacological activities such as antianxiety, antidepressant and hypnotic. Because of its high market price and medicinal values, adulteration is very common with L. angustifolia essential oil. The aim of present study is to characterize...
Article
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Osteoporosis, a chronic bone disorder, is one of the leading causes of fracture and morbidity risk. Numerous medicinally important herbs have been evaluated for their efficacy in improving bone mass density in exhaustive preclinical and limited clinical studies. Nigella sativa L. has been used as local folk medicine, and traditional healers have us...
Chapter
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Alkaloids are the most important class of secondary plant metabolites that have been considered as the major source of phytomedicine. These alkaloids are a group of phytochemicals that contains two fused, five-membered rings that share a bridgehead nitrogen atom, forming a tertiary alkaloid. Pyrrolizidine alkaloids are known for their hepatotoxic a...
Chapter
Food toxins of natural origin cover a wide diversity of macromolecules; generated by plants, algae, fungi, or degraded products of metabolism with destructive effects even at very low concentration/dose or when consumed in sufficient quantities. These toxins have diverse chemical structures and may serve definite purposes in plants or are developed...
Chapter
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Nuclear magnetic resonance (NMR) spectroscopy is a robust method, which can rapidly analyze compounds or their mixtures in complex matrices without separating or purifying them. This makes the technique ideal for analysis of foods and related products. NMR continues to be an underutilized methodology in the area of food authentication and analysis,...
Chapter
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Glycoalkaloids are abundantly found among the members of the Solanaceae family. Potatoes (Solanum tuberosum L.), tomatoes (Solanum lycopersicum L.), and eggplant (Solanum melongena L.) are the most common sources of glycoalkaloids. The most predominant glycoalkaloids present in potatoes are α-solanine and α-chaconine, and several other glycoalkaloi...
Article
Syzigium aromaticum Linn. (clove) essential oil is known for its dental analgesic property, and traditionally used as antiseptic, carminative and as important condiment in foods. Clove essential oil has high medicinal values and its adulteration is done very often with cheap edible oils. The aim of the present study was to characterize the essentia...
Article
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Background: Tongkat Ali (TA) or Eurycoma longifolia is a herbal medicine (HM) plant traditionally used to treat sexual dysfunction and enhance libido in men. Websites containing information about HM are abundant. However, studies have shown that in general the quality of websites containing information on HM is low. The present study aims to asses...
Article
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Corona virus disease (COVID-19) is a pandemic disease caused by SARS-COV2 that attacks primarily the respiratory system of the host. This disease was first reported in early December 2019, and the World Health Organization (WHO) classified the ongoing COVID-19 outbreak as a pandemic disease causing global public health emergency by mid-January 2020...
Article
Trachyspermum ammi L. Sprague syn. Carum copticum Benth. & Hook, commonly known as ajwain, is an annual aromatic and herbaceous plant of the family Apiaceae. The fruits of T. ammi are native to Egypt and widely cultivated in Iraq, Iran, Afghanistan, Pakistan, and distributed throughout India. Ajwain is commercially cultivated in Rajasthan, Madhya P...
Article
Toxicity profiles of the hydroalocholic seed extract of Psoralea Corylifolia L Fabaceae in Wistar rats
Chapter
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Foodomics has recently emerged as a new discipline that studies food and nutritional products with modern analytical tools, including mass spectrometry (MS), to ensure food quality and safety. Foodomics is currently being used as a powerful tool in food authentication. It has been used to authenticate food items such as cereals, wine, honey, chocol...
Chapter
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For both quantitative and qualitative applications, mass spectrometry (MS) has evolved to become an effective analytical instrument. The first mass spectrometer was designed in 1912 and has since progressed from studying only small inorganic molecules to biological macromolecules, with virtually no mass constraints. Research in drug discovery, in g...
Chapter
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Metabolic syndrome, formerly termed ‘Syndrome X’, is a disease of energy metabolism and storage. Metabolic syndrome is characterized by hyperglycemia/impaired glucose tolerance, dyslipidemia, hypertension, and obesity. Swertiamarin is a secoiridoid glycoside extensively found in the Gentianaceae family, which has been reported to cure many diseases...
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Chapter
Diabetes has emerged as one of the major health problems of the modern world. It is often described as a syndrome rather than a disease. It is considered to result in abnormalities in carbohydrate, fat and protein metabolism. It signifies a condition where body is unable to regulate carbohydrate metabolism due to partial or complete absence of insu...
Article
Pistacia terebinthus Linn. (Anacardiaceae) is an important species of Pistacia commonly found in Kurdistan region of Iraq. P. terebinthus is traditionally used for the treatment of several human ailments including asthma, stomach ache, sunstroke, and rheumatism. The plant is known for its antioxidant, antimicrobial, and antifungal activities. The p...
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Liquid-chromatography tandem mass spectrometry (LC-MS/MS) is a hyphenated analytical technique that combines the separating power of liquid chromatography with mass analysis capabilities. The aim of present study to identify and characterize different chemical compounds present in different (roots, leaves, stems and flowers fractions) parts of Pran...
Article
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Pistacia atlantica var. kurdica (Anacardiaceae) is a major subspecies found in the Kurdistan region of Iraq and has several beneficial bioactivities such as antioxidant, antibacterial, and antiviral. P. atlantica growing in the Kurdistan region is not yet studied phytochemically and pharmacologically. Hence, the goal of the present study is to char...
Article
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Background and Objective: High Performance Thin Layer Chromatographic (HPTLC) is a planner chromatographic technique used for the detection and quantification of natural products. An HPTLC densitometric method was developed and validated for the estimation of berberine in Berberis aristata stem bark accessions from the different sub-Himalayan regio...
Article
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Lavandula angustifolia is an important aromatic plant and rich source of linalool. L. angustifolia and its bioactive compounds have been reported to possess several bioactivities such as antioxidant, antifungal, antibacterial and antidiabetic etc. The aim of the present study is to characterize chemical compounds present in volatile oil and ethyl a...
Article
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Abstract: Background and Objective: The safety and efficacy of natural products mostly depend upon the standardization of medicinal plants. Salacia reticulata widely used traditionally, the hence present study was designed to develop a safety profile and antimicrobial activity of different extracts of S. reticulate root. Materials and Methods: Anti...
Article
Mentha spicata Linn. abundantly growing in the Kurdistan Region, and traditionally used as a flavouring agent in foods, and medicinally utilized in the treatment of stomach discomfort specifically in dyspepsia and indigestion, also used in the treatment of a common cold. The present study aims to characterize the aroma profile of essential oil obta...
Article
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Background and Objective: Hypercholesterolemia is the leading cause of the development of various diseases that made pharmaceutical companies turn towards herbal products with fewer side effects. Hyperlipidemic and reactive oxygen species in the body are important factors for the development of cardiovascular disease such as hypercholesterolemia. T...
Chapter
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Abstract: Natural products broadly incorporate plant-based product as well as marine, plants, microorganisms and minerals. There are several animal products that are also consumed by humans as a food health supplement and also medicine. Herbal products have a variety of phytocompounds. . The identification of these molecules is essential for standa...
Article
Lavandula angustifolia is a major source of high-quality fragrance and extensively used in aromatherapy. Lavender is widely found in the Jammu and Kashmir region of India. The aim of the present study to determine chemical constituents present in the essential oil of L. angustifolia flowers by gas chromatography-mass spectrometry and to evaluate it...
Article
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Pelargonium graveolens (Geranium) is a source of the finest quality of fragrance and its essential oils are used as antibacterial, and antifungal agents. The aim of the current research is to determine chemical constituents in the essential oil of P. graveolens by GC-MS and evaluate its antidiabetic activity via α-glucosidase inhibition assay. The...
Article
Gymnemic acids are triterpenoid glycosides with gymnemagenin as common aglycone found in Gymnema sylvestre (Gurmar). G. sylvestre is often used in herbal formulations because of its beneficial actions in diabetes, hyperlipidemia, and gastric problems. The purpose of the present study is to evaluate gymnemic acid-rich fraction of G. sylvestre in in-...
Article
Background Azadirachta indica (Neem) is an important medicinal plant that is traditionally known for its insecticidal, and antimicrobial properties. Objective The objective of present study was to evaluate the in-vitro antidiabetic activity and characterize the chemical constituents of Neem extract. Materials and Methods The chemical constituents...
Article
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Ayurveda captured almost all herbs in its indications for therapeutics from the period of Vedas. More than 700 plants are discussed elaborately in various classics of Ayurveda of different periods. Berberis aristata DC (Berberidaceae) an Indian medicinal plant, is an Ayurvedic herb used since ancient times. It is commonly known as Daruharidra and D...
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The success of pharmacological or analytical study depends upon proper choice of the extraction method. As extraction process is the starting step in the evaluation of any herbal drug, hence it should be designed in such a way that the extracts contain maximum amount of desired secondary metabolites. Several classical extraction methods are used si...
Chapter
This chapter deals with the structural elucidation of natural products using UV-visible, FT-IR, NMR (1D and 2D) spectroscopy and Mass spectrometry. Key concepts associated with these techniques are introduced here. Various spectra of natural compounds have been included with a brief discussion of the functional groups and structural features that t...
Chapter
Various forms of natural products such as plant extracts, pure phytochemicals and herbal formulations containing natural products offer tremendous opportunities for new drug discoveries and the credit goes to its chemical diversity. Since time immemorial medicinal plants in its various forms and have been used to treat chronic diseases such as mala...
Chapter
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The quality control of medicinal agents derived from natural sources is of paramount in ensuring safety and efficacy. The major hindrance in the acceptance of herbal medicines into modern medical practices is the lack of scientific and clinical data on the safety and efficacy of the herbal products. In general, there is a lack of strict guideline f...
Book
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Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the p...
Chapter
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Medicinal plants are recognized to fulfill human necessities like food, clothes, shelter and health. The search for eternal health and longevity to seek remedy to relieve discomfort prompted mankind to develop many ways and means of health care systems. Traditional medicines were practiced in ancient civilizations for the cure of ailments. In recen...
Chapter
This chapter deals with the structural elucidation of natural products using UV-visible, FT-IR, NMR (1D and 2D) spectroscopy and Mass spectrometry. Key concepts associated with these techniques are introduced here. Various spectra of natural compounds have been included with a brief discussion of the functional groups and structural features that t...
Article
Background Eucalyptus camaldulensis Dehnh abundantly found in Erbil, Iraq and commonly used as antispasmodic and antipyretic remedy for treating respiratory tract diseases. The present study aimed to evaluate the effectiveness of E. camaldulensis in achieving glucose homeostasis through the inhibition of α-glucosidase enzyme using in-vitro model an...
Article
The fact that Gymnema sylvestre is often used in various herbal formulations has led us to develop an HPTLC densitometric method for the quantification of its bioactive constituents i.e. gymnemic acids. Gymnemic acids are a group of triterpenoids saponins with gymnemagenin as the common aglycone. For the development of the HPTLC based analysis meth...
Chapter
Proteins and amino acids are minor constituents of wine and most wine proteins are in the range of 20–30 kDa. Proteins and amino acids make a significant contribution to the quality of wine, since they affect its taste, clarity, and stability. The proteomic technique is defined as the large-scale analysis of proteins and amino acids in a particular...
Chapter
Since ancient times, honey has been consumed for its health benefits and nutritional value, and it has been used as an adjuvant in pharmaceutical formulations. This chapter discusses types of honey, the chemical composition of honey, the extraction and separation of honey protein, and the authentication of honey protein using proteomics. Honey can...
Article
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The essential oil of Rosmarinus officinalis L. leaves growing in Erbil, Iraq was investigated by GC/MS. The essential oil (EO) was extracted by hydro-distillation method. The EO of R. officinalis leaf was examined in-vitro for antidiabetic and anticancer effects. The in-vitro α-glucosidase enzyme inhibition assay was performed to determine antidiab...
Article
Enicostemma littorale Blume (Gentianaceae) is traditionally used medicinal plant. It is locally known as Chota Chirata. It is used for the treatment of various ailments including diabetes in Indian subcontinent. Its main constituent is a secoiridoid glycoside namely swertiamarin. The aim of current study was to evaluate swertiamarin-rich fraction o...
Article
Background Olive oil and fruits are essential components of Mediterranean diets. Olive tree is a prevalent plant species and one of the important cultivated crops of Mediterranean region. The present study aimed to evaluate the effectiveness of olive in achieving glucose homeostasis through the inhibition of carbohydrate metabolizing enzymes using...
Article
Olive (Olea europaea Linn., Fam. Oleaceae) is commonly known as Zaytoon in Mediterranean region. Its fruits and oil are essential components of Mediterranean diets. Olive tree is a prevalent plant species and one of the important cultivated crops of Mediterranean region. Oleuropein is a phenolic constituents of olive, which, along with its related...
Article
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The genus Pterocephalus, one of the most important genera of Caprifoliaceae family, comprises about 30 species which are usually found in sunny, dry, rocky crevices, mostly in Europe and Western Asia. Nine species are native to the Kurdistan region of Iraq. Pterocephalus nestorianus Nab. is an important plant of this genera and locally known as Law...
Article
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Background: Andrographis paniculata Wall. commonly known as Kalmegh and widely used for the treatment of the liver complications in Indian sub-continent. It is important ingredient of several traditional herbal
Article
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Anchusa azurea (Syn. Anchusa italica) belong to the Boraginaceae family and were distributed in the temperate, especially in Mediterranean regions. Chemical studies showed that A. azurea contains mainly triterpenes and polyphenols. A. azurea possessed many pharmacological effects; these included anticancer, antioxidant and antiviral effects etc. Th...
Article
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The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. India has rich history of using many plants for medicinal purposes. Remedial plants are cooperating extremely dynamic position in customary drugs for the action of a variety of illness. However a key obstacle, which has hindere...
Article
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Traditionally Terminalia arjuna Roxb. (T. arjuna) is being used widely to cure various diseases like cardiovascular diseases, liver diseases, and cancer etc. The aim of the present study is to phytochemical analysis of petroleum ether, ethyl acetate and methanolic fractions of T. arjuna bark by GC-MS analysis. The present investigation was carried...
Article
A mixture of gymnemic acids was precipitated from the water extract of leaves of Gymnema sylvestre (Retz.) R.Br. ex Sm. (Asclepiadaceae) by acidifcation with 2 N H2SO4. The chromatographic separation of the mixture afforded fve new gymnemic acids (1-5). The compounds were characterized as Δ15 oleanane glycosides on the basis of extensive spectral d...
Article
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Key Words Gymnema sylvestre, Gymnemic acid, Asclepiadaceae, Phytochemistry, Pharmacology This review aims to present the potential information related to pharmacological actions and chemical composition of Gymnema sylvestre R.Br. (Asclepiadaceae), which is used in many Asian countries as a traditional medicine especially for the treatment of diabet...
Presentation
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Artemisia, being the widely distributed genus of the plant family Asteraceae encompasses about 500 species. Among them, Artemisia absinthium (A. absinthium) is a well-known herb commonly known as Wormwood and Afsanteen. A. absinthium reported to possess several therapeutic benefits in fever, inflammation, epilepsy, gastric problems and urinary diso...
Article
A mixture of gymnemic acids was precipitated from the water extract of leaves of Gymnema sylvestre (Retz.) R.Br. ex Sm. (Asclepiadaceae) by acidification with mineral acid. The chromatographic separation of gymnemic acids mixture afforded four new arylated gymnemic acids (1–4) along with a gymnemasaponin (5). The compounds were characterized on the...
Article
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In recent years, there has been an increased interest in the development of alternative medicines for maintaining glucose homeostasis in diabetes, specifically by screening plant extracts as well as their isolated compounds for their ability to delay or prevent glucose metabolism and absorption. The objective of present study was to evaluate the in...
Article
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Objective: Swertiamarin is a common secoiridoid found among the members of Gentianaceae. The present study aimed to establish the effectiveness of swertiamarin in achieving glucose homeostasis via inhibition of carbohydrate metabolizing enzymes by in-vitro and in-vivo studies. Materials and methods: Swertiamarin was obtained from dried whole plant...
Article
Secoiridoid glycosides comprise a group of important phyto-components from members of Gentianaceae. They possess significant antipyretic, anti-inflammatory, antidiabetic and hypolipedimic activities. This study is designed for the development of an effective method for extraction of a bioactive secoiridoid glycoside namely swertiamarin, from the wh...
Article
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Background: Momordica charantia Linn. (Cucurbitaceae) fruits are well known for their beneficial effects in diabetes that are often attributed to its bioactive component charantin. Objective: The aim of the present study is to develop and optimize an efficient protocol for the extraction of charantin from M. charantia fruits. Materials and meth...
Article
Phytochemical investigation of the methanolic extract of the stem bark of Berberis aristata (Berberidaceae) yields three new isoquinoline alkaloids characterized as 14β-hydroxy-15β-(3′,4′-dimethoxyphenyl ether)-5,6-methylenedioxy- 9(10),11(16)-tetradehydroberbinium 1, 14β-hydroxy-15β-(3′,4′-dimethoxybenzoate)-5,6-methylenedioxy-9(10),11(16)-tetrade...
Article
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Plant bitters, traditionally used against loss of appetite and fever, owe their therapeutic efficacy to the content of iridoids such as swertiamarin. The aim of the study was to develop a simple, precise, rapid, and reliable high-performance thin-layer chromatography (HPTLC) method for the estimation of swertiamarin in traditional bitters and formu...