Jason E. Warnick

• Ph.D.
• Professor (Full) at Arkansas Tech University

The zebrafish (Danio rerio) is increasingly used in a broad array of biomedical studies, from cancer research to drug screening. Zebrafish also represent an emerging model organism for studying complex brain diseases. The number of zebrafish neuroscience studies is exponentially growing, significantly outpacing those conducted with rodents or other...

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by motor, social and cognitive deficits that develop during childhood. The pathogenesis of ASD is not well characterized and involves a multifaceted interaction between genetic, neurobiological and environmental factors. Animal (experimental) models possess evolut...

Despite high prevalence of neuropsychiatric disorders, their etiology and molecular mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized as a powerful animal model in neuropharmacology research and in-vivo drug screening. Collectively, this makes zebrafish a useful tool for drug discovery and the identification...

Introduction: Anxiety spectrum disorders (ASDs) are highly prevalent psychiatric illnesses that affect millions of people worldwide. Strongly associated with stress, common ASDs include generalized anxiety disorder, panic, social anxiety, phobias and drug-abuse related anxiety. In addition to ASDs, several other prevalent psychiatric illnesses repr...

Warnick and Landis provide an overview of the major models of intercultural relations to serve as a foundation for the subsequent chapters in this text. The reader will gain a greater understanding of how the emerging field of cultural neuroscience can be applied to intercultural relations. Additionally, this chapter offers a brief guide to the boo...

This breakthrough volume brings together cultural neuroscience and intercultural relations in an expansive presentation. Its selected topics in reasoning, memory, and other key cognitive areas bridge the neuroscience behind culture-related phenomena with the complex social processes involved in seeing the world through the perspective of others. Co...

The recent challenge to the long-held assumption that emotions are natural kinds (i.e., discreet naturally-distinguishable phenomena) has raised the necessity for a closer look into the nature of affective research. If emotions are not natural kinds, there will be widespread consequences for the theoretical foundations of behavioral neuroscience an...

Scientific research and theoretical analysis of the educational enterprise have reached impressive levels of participation, funding and public support. However, when the pedagogical techniques and classroom management strategies employed are examined, an overwhelming number of teachers relying on outdated, long-disproved practices (e.g., corporal p...

The development of reliable pharmacological screening assays is an important task. However, it is based upon the ability of animal models, such as the zebrafish, to demonstrate predictive validity for a specific set of drug classes. A popular assay used for this purpose is the novel tank diving paradigm, where zebrafish behavior can easily be modul...

One of the predominate training models in graduate programs in the United States is the scientist-practitioner model (Stricker, 2000). This model is founded on the idea that graduates from such training programs would be consumers and disseminators of research. The need for such training has been made increasingly clear by the current utilization o...

While pharmacological screening assays are commonly utilized in academia and the pharmaceutical industry, the conceptual basis of these animal models has rarely been discussed. This chapter seeks to explore and understand the pharmacological screens described by the two employment strategies developed by Paul Willner. This new account of pharmacolo...

The use of animal models is an integral component of psychopharmacological research. While theoretical advancements have been made in the development and characterization of simulations and biobehavioral assays, little attention has been paid to the cross-validation, improvement and comparison of pharmacological screening assays. This article descr...

This chapter summarizes a series of investigations conducted to determine the variables predictive of positive and negative boxing performances. These studies found that previous success was the main predictor of winning a boxing bout while increased age, previous defeat and fighting in the United States when it is your homecountry were the predict...

The home-field advantage is a topic of much debate in the research literature. Thisexperiment attempted to assess whether there was an advantage for boxers performing ina home country in championship bouts due to judging bias. Official records of allchampionship bouts in 2006 were analyzed to see if the number of judges that shared thechampion's ho...

The development of the maximum predictive value measure as an evaluative standard for pharmacological screening assays could be of much value to researchers across the domain of psychopharmacology. This chapter further develops this novel assessment method by offering suggestions of alternate calculations to correct for minimally provided data. Als...

Combative sports, like boxing and the martial arts, have been a mainstay of competitive athletics throughout the history of mankind. While these sports are controversial in nature, the athletic endeavors of boxing and mixed martial arts have become multi-billion dollar industries enjoyed by millions of fans around the world. Research on these sport...

Increased attention to certain events tends to promote certain biases, like the availability heuristic, in decision making tasks. In professional boxing, the heavyweight division receives more attention than all other weight divisions. This investigation demonstrates that heavyweight boxers have received significantly more fighter of the year award...

Scientific research and theoretical analysis of the educational enterprise have reached impressive levels of participation, funding and public support. However, when you examine the pedagogical techniques and classroom management strategies employed, you find an overwhelming number of teachers relying on outdated, long-disproved practices. Further,...

The purpose of this book is to focus on breakthroughs in translational neuroscience and bio-behavioral research. This book is divided into three separate sections with each reflecting a domain in which advancements have been made. Collectively, these chapters serve to highlight the advancements made in translational neuroscience that have lead to i...

The chick anxiety-depression model is a hybrid simulation, which may prove useful as an early preclinical dual pharmacological screen for novel therapeutics. Separate dose-response studies were conducted with seven test compounds that have screened positive for antidepressant effects in rodent depression models and included prasterone (5.0-40.0 mg/...

Previous success, i.e., performance in the preceding bout and total number of wins and losses, was predictive of victory. Clarification of this effect was sought in examining whether the prior performance against a particular opponent or in a common location would be predictive of a victory in a bout against that opponent or in that locale. The car...

While development of tics during childhood for a short period of time is fairly normative (Kurlan, Behr, & Medved, 1988), youth with full-blown Tourette’s Syndrome (TS) experience a wide range of functional impairments and behavioral difficulties. These typically include school-related problems (Abwender et al., 1996; Erenberg, Cruse & Rothner, 198...

In two separate studies, sex differences in modal-specific elements of working memory were investigated by utilizing words and pictures as stimuli. Groups of men and women performed a free-recall task of words or pictures in which 20 items were presented concurrently and the number of correct items recalled was measured. Following stimulus presenta...

The clinical syndromes of anxiety and depression are now thought to exist along a temporal continuum and this construct has been modelled in a preclinical setting in chicks separated from conspecifics. This research sought to further the validity of the chick anxiety-depression continuum model. Dose-response studies using two classes of anxiolytics...

Compared to other sports, very little research has been conducted on which variables can predict victory in the sport of boxing. This investigation examined whether boxers' age, weight change from their preceding contest, country of origin, total number of wins, total number of losses, performance in their preceding contest, or the possession of a...

Anxiety and depression are currently classified as separate clinical syndromes despite considerable similarities in their symptoms, pathophysiological substrates and response to treatment interventions. An alternative hypothesis views anxiety and depression along a temporal continuum, a construct that the current research attempts to model in a pre...

While previous research has sought to validate the chick separation stress paradigm as an anxiolytic screening assay, it is unknown whether the paradigm better models a nonspecific anxiety-like state or something similar to panic disorder or generalized anxiety disorder. To characterize the anxiety model pharmacologically, cockerels were administer...

Salvinorin A, is a structurally unique, non-nitrogenous, kappa opioid receptor (KOP) agonist. Given the role of KOPs in analgesic processes, we set out to determine whether salvinorin A has antinociceptive activity in thermal and chemo-nociceptive assays. The tail-flick assay was employed to investigate 1) salvinorin A's (0.5, 1.0, 2.0, and 4.0 mg/...

Opioid systems are implicated in social attachment processes. This research sought to determine the functional contribution of each opioid receptor in modulating social attachment/separation distress. Following ICV administration of opiate probes, 7-day-old cockerels were isolated from conspecifics for a 3 min test period under either a mirror or n...

Sesquiterpene lactones possess a variety of biological activities, including anti-inflammatory activity. Two plants native to the southeastern United States, Magnolia grandiflora (L.) and Smallanthus uvedalius (L.) [syn Polymnia uvedalius (L.)], are novel sources of the sesquiterpene lactones parthenolide and enhydrin, respectively. In this study,...

Xanthohumol (XN) is the major prenylated flavonoid in hop plants and as such a constituent of beer. Pharmacological studies have shown that XN possesses marked antioxidant and antiproliferative effects. In order to study the resorption and metabolism of this compound, reversed-phase high-performance liquid chromatography is used for the determinati...

To expand the generalizability of the chick separation stress paradigm as a high-throughput anxiolytic screen, six positive drug probes (doses in mg/kg: meprobamate 15-120, pentobarbital 2.5-20.0, chlordiazepoxide 2.5-15.0, buspirone 2.5-10.0, imipramine 1-15, and clonidine 0.10-0.25) and five negative drug probes (amphetamine 0.5-4.0, scopolamine...

M.A.--Psychology. Typescript. Vita. Thesis (M.A.)--University of Mississippi, 2004. Includes bibliographical references (leaves 45-64).

In each of three experiments, participants received successive daily practice sessions on the task of recognizing inverted faces. In all practice sessions, an initial study series of 25 inverted faces was followed immediately by a test series of 17 pairs of inverted faces. Each test pair comprised a face from the study series and a new face. Comple...

Corticosterone response to separation stress and its sensitivity to the anxiolytic, chlordiazepoxide (CDP), were examined in 7-day-old domestic fowl (Gallus gallus). Saline or CDP (8.0 mg/kg) was injected intramuscularly 30 min before tests. Chicks were placed in isolation either with or without mirrors for a 15-min observation period, in which dis...

Reports two errors in the original article by S. J. Haggbloom et al (Review of General Psychology, 2002[Jun], 6[2], 139-152). The errors are noted by S. L. Black of the Dept of Psychology at Bishop's U, Lennoxville, Quebec, Canada. Black calls for a reassessment and revision of the list. The original author responds with corrections. (The following...

Reports two errors in the original article by S. J. Haggbloom et al (Review of General Psychology, 2002[Jun], 6[2], 139-152). The errors are noted by S. L. Black of the Dept of Psychology at Bishop's U, Lennoxville, Quebec, Canada. Black calls for a reassessment and revision of the list. The original author responds with corrections. (The following...

A rank-ordered list was constructed that reports the first 99 of the 100 most eminent psychologists of the 20th century. Eminence was measured by scores on 3 quantitative variables and 3 qualitative variables. The quantitative variables were journal citation frequency, introductory psychology textbook citation frequency, and survey response frequen...

Writing about emotionally salient topics to influence a participant's mood is a common experimental technique in emotion research. This study attempted to begin the biological characterization of this research paradigm. Thirty- eight participants were: 1) administered the Positive and Negative Affect Schedule (PANAS) and asked to provide a saliva s...

This investigation sought to begin detailing the biochemical changes that occur in response to a mood induction writing task. The level of positive emotion found in the participant writing samples was found to be predictive of increased levels of secretory immunoglobulin A, dehydroepiandrosterone and cortisol. These findings are in congruence with...