Janmajoy Banerjee

GITANJALI COLLEGE OF PHARMACY · Pharmacy

Background - The present work aimed to isolate one steroidal molecule from Dendrobium ochreatum. From phytochemical analysis, the presence of steroids was observed only in chloroform extracts of the stem, and the antimicrobial activities supported the extracts to be the most significant one, so work was aimed at isolating the chloroform extracts of...

This research focus to see the effect of different pre-treatment on reduction of oxalic acid content of Spinach having the oxalate content as 0.937% on dry basis. Spinach was first dried at temperature of 60 ° C, 70°C and 80°C. Dried samples were rehydrated for 2 hours before processing. Different treatments such as hot water blanching reduce the o...

Received: 9 th May 2017 Bombax ceiba, commonly known as the red silk-cotton tree, is a large, briefly deciduous tree occurring in warm monsoon forests in southern Asia. Various phytochemical constituents present in different plant parts has been already reported earlier to possess many biological activities, here in this work extraction was perform...

Achyranthes aspera is the important medicinal herb found as weed throughout tropical region of Nepal and famous for its folk medicine use, here in this work the different plant parts (root, stem and leaves) were subjected to extractions with different polarity solvent (gradient elution) and based on the presence of phytoconstituents in different ex...

Conventionally, a series of five derivatives of oxazolone were synthesized by two schemes using different carbonyl compounds with benzoyl glycine in presence of acetic anhydride as dehydrating agent, zinc oxide as catalyst and ethanol as solvent. The yield values and rate of reaction in term of time was compared which concluded the aldehydes are ef...

A simple, highly efficient and green procedure for the condensation of aryl and alkyl 1, 2-diamines with 1,2-diketones or alphahydroxyketones in the presence of different catalyst, method and solvent is described. Using this method, quinoxaline derivatives as biologically interesting compounds are produced in high to excellent yields and short reac...

Helminthes infections are more common in poor countries where people suffer from poor health hygiene and sanitation, though there are lot of marketed drugs available for these disease but the interesting thing about antihelminthics is that they are either pypirazine or benzimidazole derivatives, so as medicinal chemist the attention will be drawn t...

A series of novel pyrazolone derivative were synthesized by two different schemes (scheme-1 by the reaction of phenyl hydrazine and ethyl acetoacetate with substituted benzaldehydes PYR-1 to PYR-4) and (by the reaction of synthesized chalcone with phenyl hydrazine PYR-5) and characterised with its physical parameters (M.P, colour, %yield, solubilit...

A study on the pretreated banana and wheat bran incorporated milkshake was carried out to develop a fiber enriched milk product at an acceptable level and extended shelf life at room temperature. Milk shake was prepared in laboratory using skimmed milk, stabilized wheat bran and pretreated banana pulp. Different eight samples were formulated taking...

Imidazole is a five membered, heterocyclic ring containing two hetero (nitrogen) atoms and two double bonds. Many imidazoles molecules are synthesized either through fusion or substituting various functional groups in the lead moiety. Several methods of synthesis were reported till date. Imidazole has already been reported to possess many biologica...

This study was performed to evaluate the presence of phytoconstituents, antimicrobial and antioxidant activity of Dendrobium ochreatum. (Orchidaceae) stem, root leaf extracts. In this study nine different solvent extracts were subjected to examination. Preliminary phytochemical analysis revealed that the ethanolic extract of root, stem and hexane:...

This study was performed to evaluate the presence of phytoconstituents, antimicrobial and antioxidant activity of Dendrobium ochreatum. (Orchidaceae) stem, root leaf extracts. In this study nine different solvent extracts were subjected to examination. Preliminary phytochemical analysis revealed that the ethanolic extract of root, stem and hexane:...

Oxazolones are five membered heterocyclic entity containing oxygen and Nitrogen. It is important synthons for the synthesis of various biologically active compounds and is an important pharmcophore of synthesized drugs. Oxazolone is being synthesized in many ways since 1883. It shows marked pharmacological activity such as: antimicrobial, anifungal...

Oxazolones are five membered heterocyclic entity containing oxygen and Nitrogen. It is important synthons for the synthesis of various biologically active compounds and is an important pharmcophore of synthesized drugs. Oxazolone is being synthesized in many ways since 1883. It shows marked pharmacological activity such as: antimicrobial, anifungal...

INTRODUCTION Diabetes mellitus (DM) is a chronic disease characterized by a deficiency in insulin production and its action or both. That leads to prolonged hyperglycemia with disturbances in most metabolic processes inside the human body. Untreated cases show severe tissue and vascular damage leading to serious complications such as retinopathy, n...

Achyranthes aspera is the important medicinal herb found as weed throughout tropical region of Nepal. It belongs to the family amaranthaceae. It is known as dattiwan in nepali, Apamarg in Sanskrit, prickly chaff flower in English and Naayuruvi in tamil. The medicinal plants are used for treatment of various diseases because of their safety and effe...

Benzimidazole is a heterocyclic aromatic organic compound. It is an important pharmacophore and privileged structure in medicinal chemistry. It plays a very important role with plenty of useful therapeutic activities such as: antiulcers, antihypertensives, analgesic, anti-inflammatory, anti-virals, antifungals, anticancers, and antihistaminics. The...

: Various novel, mild, eco-friendly and efficient methods has been developed for the preparation of quinoxaline derivatives in high yields via condensation of aromatic diamine and 1,2-dicarbonyl compounds or alphahydroxyketones in the presence of different catalyst such as CuSO4/KMno4 , iodine, phenol similarly by using different solvents such as w...

Benzimidazole is a heterocyclic aromatic organic compound. It is an important pharmacophore and privileged structure in medicinal chemistry. It plays a very important role with plenty of useful therapeutic activities such as: antiulcers, antihypertensives, analgesic, anti-inflammatory, anti-virals, antifungals, anticancers, and antihistaminics. The...

Bergenia ciliata of Nepalese origin has been investigated for pharmacognostical, phytochemical and biological activities. The plant was subjected for extraction by ethanol, distilled water, and butanol: hexane (2:1) successfully. The preliminary phytochemical studies of the plant showed the presence of alkaloids, carbohydrates, cardiac glycosides,...

Bergenia ciliata of Nepalese origin has been investigated for pharmacognostical, phytochemical and biological activities. The plant was subjected for extraction by ethanol, distilled water, and butanol: hexane (2:1) successfully. The preliminary phytochemical studies of the plant showed the presence of alkaloids, carbohydrates, cardiac glycosides,...

Thiazoles the five member ring system with two hetro atoms (S, N) in the heterocyclic ring at 1, 3 positions. Thiazoles are useful structural units in the field of medicinal chemistry and have been reported to exhibit a variety of biological activity. Thiazoles are a class of organic compounds related to azoles with a common thiazole functional gro...

Thiazoles the five member ring system with two hetro atoms (S, N) in the heterocyclic ring at 1, 3 positions. Thiazoles are useful structural units in the field of medicinal chemistry and have been reported to exhibit a variety of biological activity. Thiazoles are a class of organic compounds related to azoles with a common thiazole functional gro...

Bergenia ciliata is a potent indigenous folk medicine that has been proved fruitful in the treatment of various adverse conditions of the body. The major chemical constituents of plant include tannic acid, gallic acid, glucose, metarbin, albumen, bergenin, (+)-catechin, gallicin. Bergenia ciliata was subjected to bioactivity analysis. The plant has...

Pyrazoline is a five member heterocyclic ring which is a versatile lead compound for designing potent bioactive agents. The review of the literature shows that the pyrazoline derivatives are quite stable and has inspired the chemists to synthesize the new pyrazoline derivatives. The past studies of pyrazoline derivative revealed that they are usefu...

Ten novel oxazolone derivatives 2a‐j were synthesized by microwave synthesizer by reacting 2‐furoyl glycine with substituted aromatic and hetero aromatic aldehyde in presence of sodium acetate and acetic anhydride. All these compounds were characterized by UV, IR, 1 HNMR, mass spectroscopy and elemental analysis. The synthesized compounds were scre...

A novel series of benzothiazole derivatives were synthesized and assayed in vivo to investigate their hypoglycemic activity by streptozotocin-induced diebetic model in rat. These derivatives showed considerable biological efficacy when compared to glibenclamide, a potent and well known antidiabetic agent as a reference drug. All the compounds were...

Ginger, (Zingiber officinale Roscoe, Zingiberacae) is one of the important medicinal plant which naturally occurs in various country like India, China, South East Asia, West Indies, Mexico and other parts of the world. This natural gold has been consumed worldwide as a spice and flavoring agent from the ancient time. Ginger plants are generally 1-3...