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Project leader e-Proteins which is the world leader in avidin derivatives production which are the best alternatives to streptavidin. Our derivatives are superior and address the main challenges of previously used streptavidin in: - Non-specific binding protein : Neutralite avidin - High binding capacity for purification : UltraCoat50 - High binding capacity Anny question? DO not hesitate to ask me directly.
Objectives: Monoclonal antibodies are important in the treatment of rheumatoid arthritis (RA). This is the first trial to monitor the effect of adalimumab dose escalation in persistently active RA. The aim of this study was to identify the response to adalimumab to improve the basis for making decision in relation to actual drug capacity in serum....
*authors are listed in alphabetical order The aim of the open source imaging initiative (OSI²) is to collaboratively share research in MR technology and building a quality, affordable open source MR scanner. Combining innovation and open source (OS) approaches will generate global value by reproducible science and development and will allow a majo...
A slow response to omalizumab (anti-IgE) in CSU patients is strongly correlated with IgG-anti-FcεRI-mediated serum-induced basophil histamine release suggesting that, in these patients, effects on FcεRI are critical for the mechanism of action of omalizumab.
Multiple myeloma (MM) is an aggressive incurable plasma cell malignancy with a median life expectancy of less than seven years. Antibody-based therapies have demonstrated substantial clinical benefit for patients with hematological malignancies, particular in B cell Non-Hodgkin's lymphoma. The lack of immunotherapies specifically targeting MM cells...
Stomatin proteins oligomerize at membranes and have been implicated in ion channel regulation and membrane trafficking. To obtain mechanistic insights into their function, we determined three crystal structures of the conserved stomatin domain of mouse stomatin that assembles into a banana-shaped dimer. We show that dimerization is crucial for the...
The stomatin-domain defines a family of proteins that are found in all classes of life. The ubiquity of stomatin-family proteins and their high degree of homology suggest that they have a unifying cellular function, which has yet to be defined. The five stomatin family proteins in mammals show varying expression patterns and different sub-cellular...
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated. It is currently unclear whether Leishmania-infected phagosomes uniformly pass through a Rab5(+) stage on their intracellular path to compartmen...
If you work in the laboratory setting, or in the diagnostic field, it is very likely that you use Streptavidin or NeutrAvidin. I would like to hear your opinion and the experiences on the difference between NeurAvidin vs. Streptavidin
I´m working on a protein complex bigger than 1500 kDa and search for protein marker to detect the protein complex on SDS or SEC. Any suggestion is welcome.
This would give the author more flexibility so that there do not have to wait three month before submitting to the next journal.