Janani Manochkumar

Janani Manochkumar
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Janani verified their affiliation via an institutional email.
Vellore Institute of Technology University | VIT · Division of Plant Biotechnology

Doctor of Philosophy*
Research Scholar at Vellore Institute of Technology

About

11
Publications
733
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131
Citations

Publications

Publications (11)
Article
Full-text available
Astaxanthin (ASX), “king of carotenoids”, is a xanthophyll carotenoid that is characterized by a distinct reddish-orange hue, procured from diverse sources including plants, microalgae, fungi, yeast, and lichens. It exhibits potent antioxidant and anti-ageing properties and has been demonstrated to mitigate ultraviolet-induced cellular and DNA dama...
Article
Introduction: The marine microalga Isochrysis galbana is prolific producer of fucoxanthin, which is a xanthophyll carotenoid with substantial global market value boasting extensive applications in the food, nutraceutical, pharmaceutical, and cosmetic industries. This study presented a novel integrated experimental approach coupled with machine lear...
Preprint
Full-text available
The marine microalgae, Isochrysis galbana is a prolific producer of fucoxanthin which is a xanthophyll carotenoid with substantial global market value boasting extensive applications in the food, nutraceutical, pharmaceutical, and cosmetic industries. Although supplementation of different phytohormones to medium enhances fucoxanthin production, the...
Article
Advancements in genome mining, high-throughput sequencing and experimental techniques have generated an enormous amount of data on natural products. This has led to the design and development of advanced machine learning (ML) and artificial intelligence (AI) algorithms which have simplified the search for novel natural products in the 21st century....
Article
During the last decade, genomic, transcriptomic, proteomic, metabolomic, and other omics datasets have been generated for a wide range of marine organisms, and even more are still on the way. Marine organisms possess unique and diverse biosynthetic pathways contributing to the synthesis of novel secondary metabolites with significant bioactivities....
Chapter
The proposal on the Anthropocene suggests that the Earth has entered a contemporary ecological era, in which climate changes and human activities massively impact the environment universally. This new anthropogenic epoch brings exceptional challenges to the plant diversity in biocultural landscapes, thus preventing their benefits to human well-bein...
Article
Background Recent studies revealed a substantial role of carotenoids to treat respiratory diseases. This review aimed to give an updated overview of the investigational evidence on the preventive properties of carotenoids against respiratory diseases both in vitro and in vivo along with their pathophysiology and mechanisms of action. Hypothesis Ca...
Article
Background Despite the advancements in cancer research, cancer's molecular mechanism and therapeutic response frequently remain a mystery. Previous reports mainly focused on natural therapeutic compounds as drugs. Over the past few decades, several initiatives focused on isolating and identifying novel marine compounds as anticancer agents. This re...
Article
Background Despite advances in research on neurodegenerative diseases, the pathogenesis and treatment response of neurodegenerative diseases remain unclear. Recent studies revealed a significant role of carotenoids to treat neurodegenerative diseases. The aim of this study was to systematically review the neuroprotective potential of carotenoids in...

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