Jana Parízková

Institute of Endocrinology · Department of Obesitology

Normal-weight obesity appears to be an extended diagnosis/syndrome associated with insufficient physical fitness levels and inadequate eating habits at least from school years. However, its relation to long term health parameters in pre-school children remains unknown, even though pre-school age is crucial for the determining healthy lifelong habit...

Changes in lifestyle can be significantly reflected in growth and development. Adaptations to reduced levels of physical activity, together with non-corresponding nutritional intakes, can result in body build and body composition changes at an early age. The present cross-sectional study aimed to evaluate the secular trend of modifications of body...

Introduction Adipose tissue distribution is one of the factors influencing development of cardiometabolic complications associated with overweight and obesity. Waist circumference and waist/height ratio (WHtR) are markers of central adipose tissue distribution The aim of the study was to compare overweight/obesity and adipose tissue distribution in...

Background: Normal weight obesity in children has been associated with excessive body fat, lower bone density and decreased total lean mass. However, no studies have been done into whether normal weight obese children differ in skeletal robustness or lean mass development on the extremities from normal weight non-obese, overweight, and obese peers...

BMI, skinfold thickness, and circumferential measures were assessed in groups of normal healthy Czech boys ( n=1764 ) and girls ( n=1762 ) 3–6 years of age in the late 1950s and 1960s (sample C), in the 1990s (sample B), and in 2014–2016 (sample A). During these decades BMI has not changed significantly, and in selected groups (boys 3, 5, and 6, gi...

Secular trends of adiposity and motor development in preschool children since the fifties of the last century up to the beginning of this millennium were analyzed so as to reveal possible changes due to continuously differentiating lifestyle. In preschool children ( n = 3678 ) height, weight, skinfold thickness over triceps, subscapular, and supr...

The main aim of this article is the review of selected longitudinal studies (lasting from several months up to fourteen years in the same groups) investigating body fat indicators in relationship to physical activity, exercise and fitness levels in normal weight, obese children and adolescents from preschool age. Special attention was focused on co...

Background. Childhood overweight prevalence increases worldwide. The aim of the study was to clarify the change in underweight, overweight and obesity in seven year old Czech children since 1951. Data on underweight, overweight and obesity prevalence were obtained using repeated cross-sectional surveys. In 1951-2001 six Czech National Anthropologic...

Nutritional and motor individuality vary significantly among human subjects, and their mutal relationship is decisive for a desirable energy balance and turnover with regard to body composition, physical fitness level and health. Early establishment of optimal individualities, with regard to genetic, epigenetic and other factors which influence the...

Published in Endocrine Abstracts 2010; 22: P716.

The objective of this paper was an evaluation of change in prevalence of overweight and obesity in Czech children, and a comparison of cut-off points for body mass index references from the Czech Republic (CzR), International Obesity Task Force and WHO. The authors conducted a survey in 7-year-old children, and compared data from 1951, 1981, 1991,...

To achieve a higher level of overall fitness and to prevent obesity with accompanying comorbidities requires life-long effort starting early in life during the prenatal period. A sufficiently intense, regular, and ongoing physical activity regime and adequate exercise are indispensable, along with monitored diet. Once acquired, a desirable level of...

Published in Obesity Reviews 2010; 11(Suppl. 1): 412.

Childhood obesity is a global health problem. For monitoring of trends in obesity prevalence and comparison between countries standardized methods are necessary. WHO/Europe launched the "Childhood Obesity Surveillance Initiative" project in 2006 aiming to monitor childhood obesity and associated factors in European countries. This paper provides an...

With regard to the increasing prevalence of obesity already during growth, special attention has been focused on all the possible factors, which can cause and/or contribute to its development. In addition to genetic and environmental influences over the course of the whole life, information was found on the early factors, which influence the organi...

The classification of a new clinical unit DSD - Disorders of Sexual Development is provided. Emphasis is placed on the lifelong consequences and social problems faced by patients with these disorders.

This article describes a web page which offers miscellaneous and widespread educational material about machine oriented languages.Príspevok dáva do povedomia webovú stránku, ktorá ponúka rozmanitý a rozsiahly náučný materiál k téme strojovo orientovaných jazykov z rôznych aspektov.

The increasing prevalence of obesity during growth and development is significantly related to the education of children, and also to that of parents who influence food intake and physical activity from the beginning of life. The effect of maternal level of education has been shown in regular anthropometric surveys in 10-year intervals since 1951....

Experimental and epidemiological studies suggest that calcium intake is inversely related to weight gain. Calcium of dairy origin has been shown to be more effective in promoting weight loss. However, clinical studies yielded controversial results concerning the role of calcium intake in weight change. The aim of this study was to ascertain whether...

Among the factors influencing weight loss and maintenance, psychobehavioral, nutritional, metabolic, hormonal and hereditary predictors play an important role. Psychobehavioral factors influence adherence to lifestyle changes and thus weight loss maintenance. The outcome of short-term weight reduction treatment is mainly affected by changes in ener...

Aim: To reveal a role for short-term spa weight management in changes of select anthropometric, psychobehavioural and hormonal indices. Methods: Sixty seven overweight/obese women participated in 4-wk comprehensive obesity management programme in the Spa Obesity Unit. The energy and nutrient content of meals prepared in the central kitchen was calc...

Reduction of energy output due to lowered physical activity is considered as one of the most important factors in the development of obesity, especially during childhood. Questionnaires, pedometers, sports testers (which register pulse frequency), or doubly labelled water (D218O) method are used to assess physical activity and energy output. The WH...

The aim of the study was to compare and evaluate psychological traits of eating behaviour assessed using the Eating Inventory (El) known also as the Three Factor Eating Questionnaire (TFEQ) and their relationship to body adiposity, health and social characteristic in a quota sample of Czech adults. The sample included 1624 women and 1429 men who we...

The purpose of this study was to estimate the change in overweight and obesity prevalence and the influence of socioeconomic status and parental obesity on overweight and obesity of children and adolescents in the Czech Republic. The roles of family history of obesity, dietary factors and physical activity were evaluated. The quota sample of 1,417...

[corrected] A protective effect of breast feeding on the development of obesity has been clearly demonstrated. Several studies associated higher protein intake in postnatal period with the earlier "adiposity rebound" and the higher BMI in later life. Twenty eight girls born at 34th week of pregnancy (weight: 2.22+/-0.31 kg, length: 45.2+/-2.5 cm, B...

Obesity is the most widespread global metabolic disease and is a significant public health problem. During the last three decades, many countries in Asia are facing a looming health crisis of obesity because of rapid modernization, dramatic changes in lifestyle, high fat and sugar diet, and reduced physical activity resulting partly from the Wester...

To study the relationships between the Eating Inventory (EI) factors (restraint, disinhibition and hunger), body adiposity and prevalence of selected diseases in a quota sample of Czech adults. The sample included 1429 men and 1624 women who were interviewed individually by trained investigators. The sample was quota representative--for gender, age...

Polyunsaturated fatty acids of n-3 series (n-3 PUFA) were shown to increase basal fat oxidation in humans. The aim of the study was to compare the effect of n-3 PUFA added to a very low calorie diet (VLCD), with VLCD only during three-week inpatient weight reduction. Twenty severely obese women were randomly assigned to VLCD with n-3 PUFA or with p...

Childhood Obesity Prevention and Treatment, Second Edition summarizes the latest scientific knowledge on obesity in children. This edition focuses on the developmental aspects of obesity, especially on the influences and factors predisposing individuals to obesity from early periods of life. This new body of knowledge stems from both basic research...

Controversy about the proportion of animal protein to be included in humans' Recommended Daily Allowance has affected the quantity of meat consumed, as well as the type of meat, and this has varied over the years. This study of meat consumption in the Czech Republic until the end of the last millennium concludes that meat protein must be balanced w...

Changes of fat distribution were followed up in Czech and Slovak children from 1.5 to 15 years of age, using centrality indices, which relate the values of skinfolds on the trunk to the skinfolds on the extremities, head and neck. Up to 5 years of age, subcutaneous fat was deposited relatively more on the extremities, head and neck than on the trun...

To study whether or not the amount of vitamin A consumed affects the resting metabolic rate (RMR) and fat oxidation at rest in severely obese subjects. In 239 obese subjects, RMR and fasting respiratory quotient (RQ) were determined by indirect calorimetry. Vitamin A consumption was calculated by the Czech PC program 'Nutrition'. The relation betwe...

Modifications of social, political, cultural, nutritional and behavioral factors in the Czech Republic during the nineties were not homogeneous, and/or of the same rate and character; however, the effect on child population was manifested. In all former socialist countries social contrasts have increased along with the modifications of the availabi...

Fourteen pairs of obese female monozygotic twins were recruited for a study of genetic influences on serum and adipose fatty acid (FA) composition. Following 1 wk of inpatient stabilization, fasting serum and adipose tissue obtained by surgical excision were analyzed by thin-layer and gas chromatography. Intrapair resemblances (IPR) for individual...

We have reported strong intrapair resemblances (IPRs) in serum phosphatidylcholine (PC) fatty acid composition within adult monozygotic twins living apart. This study assessed the contribution of genetic factors to changes in serum and adipose tissue fatty acids resulting from weight loss and followed by a subsequent year of weight maintenance. Ele...

Fasting plasma levels of both cortisol and sex hormone binding globulin (SHBG) in obese women were significantly inversely related to anthropometric characteristics of body fat distribution. It means that a central accumulation of body fat might be partly mediated by cortisol and SHBG levels. Significant within-pair resemblance observed in plasma c...

Adipose tissue distribution predicts development of obesity complications better than total adipose tissue content. The aim of the study was to evaluate the role of the hormonal factors contributing to the adipose tissue distribution in obese females. The cohort examined consisted of 94 women in the range of overweight to obesity, aged 44.2 +/- 11....

The first aim of the present study was to evaluate the changes in serum levels of cortisol, testosterone, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEA-S) and sex hormone-binding globulin (SHBG) in response to weight loss induced by one month of treatment with a very low-calorie diet (VLCD) in twelve pairs of female obese mon...

To assess the genetic contribution to determinants of therapeutic weight loss in obese female identical twins. Subjects were studied for 40 days on an inpatient unit in three phases: 7 baseline days; 28 days of weight reduction by a very low calorie diet (1.6 MJ per day); and 5 days after weight reduction. Fourteen pairs of premenopausal obese fema...

Obesity which starts to develop during early growth predisposes to more frequent and more serious obesity in later periods of life, which is also accompanied in greater extent by increased morbidity by cardiovascular, metabolic etc. diseases. This follows from a number of unfavourable changes accompanying not only the amount and type of distributio...

To assess intrapair resemblance in changes of body weight, total body fat, fat distribution, resting metabolic rate, fasting respiratory quotient and cardiovascular disease risk factors in response to therapeutic weight loss in female obese identical twins. Patients stayed for 40 days on an inpatient metabolic unit under careful supervision. The st...

The overall situation as regards dietary intake and nutritional status in the countries of Central and Eastern Europe has varied considerably during previous decades; however, after the political, social and economic changes during the nineties these differences have increased further, especially in the areas with low GDP and war, and in the region...

The overall situation as regards dietary intake and nutritional status in the countries of Central and Eastern Europe has varied considerably during previous decades; however, after the political, social and economic changes during the nineties these differences have increased further, especially in the areas with low GDP and war, and in the region...

A high fasting respiratory quotient (RQ) was observed during the treatment by very low calorie diet (VLCD) in obese patients who regained weight at two-year follow-up (weight regainers) or in those who exhibited repeated cycles of weight loss with a subsequent weight regain (weight cyclers). In contrast obese patients who succeeded to retain the we...

It has been rare to find studies of the influence of nutrition on growth that have incorporated careful measurements of physical activity. This paper reviews interactions between physical activity and nutrition in early life and finds that such interactions have a significant influence on growth and later metabolism. Young animals are generally cha...

Guidelines for the management of obesity include recommendation about diet, exercise, behavioral modification, drug therapy and bariatric surgery in the comprehensive management of an obese patient. It is emphasized that the treatment of obesity should be individually tailored according to the age of the patient, degree and phase of obesity, body f...

A group of 318 obese patients followed-up at the Obesity Unit in Prague in 1995-1997 was included into a study. Their treatment was based on the standard combination of a weight reduction diet, physical activity and behavioural intervention. In patients with more severe degrees of óbesity VLCD in one daily portion, pharmacotherapy, in-patient regim...

An increasing prevalence of obesity all over the world reflects a lack of effective measures in both prevention and treatment of obesity. Obesity as a disease has been underestimated by the lay-public as well as health care providers. However, obesity represents a substantial health problem associated with a decreased quality of life. Obesity is li...

The purpose of this study was to monitor changes in body and skin temperatures, heat production, subjective shivering, cold sensation and body fat content in humans after intermittent cold water immersion. Repeated exposures of young sportsmen to cold water (head out, 14 degrees C, 1 h, 3 times per week for 4-6 weeks) induced changes in regulation...

Recommended dietary allowances were prepared by the Scientific Committee for Food an published by the Commission of the European Communities in 1993. Recommended allowances for energy were evaluated on the basis of basal metabolic rate (BMR), calculated individually with the help of the regression equations prepared by Expert Consultation of FAO/WH...

BACKGROUND. In middle-aged and elderly men the cardiovascular mortality in this country is still relatively high. The objective of the presented work was therefore the validation of simple parameters of fat deposition as a risk factor in order to select subjects at risk where preventive measures are called for. METHODS AND RESULTS. In 68 men aged 4...

To study the relation between anthropometry, diet and blood lipids during pregnancy and anthropometry and cord blood lipids in newborns. Longitudinal study during pregnancy. Population study. A group of 70 volunteer pregnant women attending the Maternity Advisory Service were recruited at the 1st trimester and studied during pregnancy. By the end o...

68 middle aged men (43.8 +/- 7.4 years) without apparent health problems were examined. Medical check up, individual and family history, physical performance test on a bicycle ergometer, blood lipid level (total, T-, HDL-, LDL-cholesterol, triglycerides) and anthropometric measurements were executed. No serious health problems and complaints were a...

The aim of the study was to evaluate a new bioimpedance method for assessment of body fat employing bipedal electrodes instead of those attached to both upper and lower extremities. The new analyzer (TBF-105, Tanita Corp., Tokyo, Japan) enables simultaneous measurements of body weight and total body resistance in a subject standing on the stainless...

Abdominal type of obesity is linked to risk factors of atherosclerosis and to metabolic diseases. 216 women, aged 17 to 67 years, mean age 43.1 +/- 0.76, mean weight 108.7 +/- 1.6 kg and mean BMI 39.57 kg/m2, were examined. Body composition was assessed by hydrodensitometry, fat distribution was determined by simple anthropometric measurements (wai...

The purpose of the present study was to investigate the validity of commercial instrumentation using near infrared interactance (NIRI) to predict total body fat. 169 adult men and women, aged 18–48 years, with markedly diverse body composition, were measured. The optical density (OD) at six sites (biceps, triceps, subscapular, suprailliac, thigh an...

Treatment of obesity with strict reducing diets is as a rule associated with the development of energetic efficiency manifested among others also by a decline of energy expenditure. The objective of the trial was to test whether addition of oils containing triacylglycerols with medium-chain fatty acid can prevent this decline and whether their admi...

Sixteen adolescent cross-country skiers (6 males, 10 females) were assessed during a period of preparation carried out in the school year (period I) and during a period of training in the mountains before competition (period II). Body mass index (BMI), body composition (calculated from skinfolds) and dietary intake were ascertained over a 1 week pe...

Hitherto published experimental and clinical studies provide controversial findings as regards the relations of risk factors of atherogenesis and ischaemic heart disease and variations of body weight. The objective of the present study was to find out whether variations of body weight in women with severe obesity influence the incidence of some oth...

This study was designed primarily to identify relationships among indices of muscle tissue structure (m. vastus lateralis) and of somatic qualities (anthropometric parameters) in 44 untrained men and 105 well-trained athletes. The ratio of glycolytic to oxidative muscle fibres was significantly less (P < 0.05) in endurance athletes as opposed to bo...

One-month treatment of obese patients (body mass index, 39.44 +/- 0.94, measured in kg/m2) with a very-low-calorie diet (VLCD) resulted in a significant weight loss, which was higher in men than in women. In contrast, the decrease of percent fat content was higher in gynoid obese women than in men or women with android fat distribution. In females...

To evaluate a long-term efficacy of very-low-calorie-diet (VLCD) treatment, 42 obese patients were reexamined 1 y after the initiation of the weight reduction by VLCD treatment for 1 mo. All the subjects participating in the long-term outpatient weight-reduction regime were divided into weight losers and regainers according to the weight change ach...

Human growth, physical fitness and nutrition under various environmental conditions, J.Parizkova growth, exercise, nutrition and fitness in China, J.Chen social epidemiology of nutrition in the Ranga Reddy district of India and its implications for human resources development, K.Satyanarayana et al growth, maturation, body composition and maximal a...

Among the measurements of nutritional status and health the evaluation of physical fitness and functional capacity have an important place. They belong to the most important characteristics of the human organism: its level of development, growth, and maturation. Their reduction and deterioration are often the first signs of a certain degree of maln...

Assessment of the skinfold thickness in obese patients by means of a caliper makes it possible to determine the percentage of total body fat and provides information on the distribution of subcutaneous body fat and thus to characterize the type of obesity. In more severe obesity it is not possible to differentiate reliably by means of classical cal...

The authors give an account of anthropometric examinations in obese patients. These methods are used not only for quantitative assessment of the degree of obesity but also to define the body fat distribution. The predominant body fat distribution in the upper body half on the chest and abdomen is typical for android obesity and is, contrary to gyno...

The low-energy protein diet providing 1559 kJ is the first accurately defined diet for the treatment of obesity in the CSSR. The daily amount contains 4.0 g fat, 33.0 g protein, 50.0 g carbohydrate, 5.6 g fibre and daily recommended allowances of vitamins. The diet is enriched with potassium, magnesium and iron. The low-energy protein diet was used...

A new very low energy formula diet containing 1560 kJ (373 kcal) per day was employed in the treatment of 49 obese patients. The treatment, of 4 weeks duration, included aerobic physical exercise and behavioural intervention. This kind of therapy resulted in a significant decrease (P less than 0.001) of both weight (-10.60 +/- 0.46 kg) and body mas...

Wistar rats were genetically selected for either high (+A) or low (-A) locomotor activity level in a new environment. The response to the novelty was tested in all filial generations at the age between 75-80 days of life. Groups of 15 +A male rats selected from the 11th and 12th generations were placed in the individual cages connected with rotatio...

The relationships between \(\dot V_{O_2 } \) at rest, \(\dot V_{O_{2max} } \) and \(\dot V_{O_2 } \) during submaximal work on a treadmill with body weight, height and lean body mass assessed by densitometry were analyzed annually in 39 boys aged 11 to 18 years. Interindividual differences in \(\dot V_{O_2 } \) at rest and \(\dot V_{O_{2max} } \) d...

The relationships between nutrition, body size and composition, and functional characteristics vary for different sports. Despite the selection of and adaptation to closely comparable exercise regimes, interindividual variability is remarkable. A high proportion of lean body mass, great aerobic power, a peak ventilatory threshold, and mechanical ef...

The relationship between spontaneous physical activity, physical fitness and serum high density lipoprotein cholesterol concentration (HDL-C), triglycerides and creatine kinase activity was examined in a group of 3-5 year old children. Their somatic development, skinfold thickness, modified step test performance, psychological development and fine...

A group of 3-5-year-old children (n = 22) with a level of somatic development and physical fitness (modified Step test) that corresponded to a previously measured representative sample was studied. The depot fat proportion was 16.3 +/- 4%, and obesity was absent. Lean body mass (LBM) was 16.1 +/- 1.8 kg. As in previous studies, the fat intake was h...

A group of 3‐5‐year‐old children (n = 22) with a level of somatic development and physical fitness (modified Step test) that corresponded to a previously measured representative sample was studied. The depot fat proportion was 16.3 ± 4%, and obesity was absent. Lean body mass (LBM) was 16.1 ± 1.8 kg. As in previous studies, the fat intake was highe...

The conditions under which increased motor activity leads to raised resistance of the myocardium to injury were studied. Motor activity was raised by running on a treadmill; myocardial resistance was evaluated quantitatively from the extent of isoprenaline (ISO)-induced lesions. After 3 weeks of forced running (5 days a week), using an adequate dai...