Jan G Nijhuis

Jan G Nijhuis
Maastricht University | UM · Department of Obstetrics and Gynecology

Prof. MD PhD

About

321
Publications
27,841
Reads
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7,647
Citations
Additional affiliations
March 1999 - present
Maastricht Universitair Medisch Centrum
Position
  • Professor (Full) and head of the dept Ob/Gyn

Publications

Publications (321)
Article
Background Stillbirth is a major public health problem, but measurement remains a challenge even in high-income countries. We compared routine stillbirth statistics in Europe reported by Eurostat with data from the Euro-Peristat research network. Methods We used data on stillbirths in 2015 from both sources for 31 European countries. Stillbirth ra...
Article
Full-text available
Objective: Robson's Ten Group Classification System (TGCS) creates clinically relevant sub-groups for monitoring caesarean birth rates. This study assesses whether this classification can be derived from routine data in Europe and uses it to analyse national caesarean rates. Design: Observational study using routine data SETTING: 27 EU member st...
Article
Objective To compare, in women with twin pregnancy with the first twin in cephalic position, neonatal morbidity and mortality rates after actual 1) Vaginal delivery (VD) both twins versus 2) unplanned Cesarean Delivery (CD) of both twins and 3) after VD of twin A and CD of twin B (combined delivery). Study Design We describe a nationwide cohort st...
Article
Objectives Discussing the individual probability of a successful vaginal birth after caesarean (VBAC) can support decision making. The aim of this study is to externally validate a prediction model for the probability of a VBAC in a Dutch population. Methods In this prospective cohort study in 12 Dutch hospitals, 586 women intending VBAC were incl...
Article
Objective: To compare changes in foetal, neonatal and perinatal mortality in the Netherlands in 2015, relative to 2004 and 2010, with changes in other European countries and regions. Design: Descriptive population-wide study. Method: Data from 32 European countries and regions within the Euro-Peristat registration area were analysed. These cou...
Article
Full-text available
Objectives Fetal alcohol spectrum disorders (FASD) is a worldwide problem. Maternal alcohol consumption is an important risk factor for FASD. It remains unknown which alcohol consumption patterns most strongly predict FASD. The objective of this study was to identify these. Design Systematic literature review. Methods We searched in PubMed, Psych...
Preprint
Full-text available
Objectives: Fetal Alcohol Spectrum Disorders (FASD) is a worldwide problem. Maternal alcohol consumption is an important risk factor for FASD. It remains unknown which alcohol consumption patterns most strongly predict FASD. The objective of this study was to identify these.Design: Systematic literature review.Methods: We searched in PubMed, PsychI...
Article
Background: International comparisons of stillbirth allow assessment of variations in clinical practice to reduce mortality. Currently, such comparisons include only stillbirths from 28 or more completed weeks of gestational age, which underestimates the true burden of stillbirth. With increased registration of early stillbirths in high-income cou...
Article
Full-text available
Introduction: The purpose of this study was to evaluate the changes in maternal quality of life (QOL) from pregnancy to 6 weeks after delivery between routine labor epidural analgesia (EA) and pain relief on maternal request only. Methods: \Women delivering of a singleton in cephalic presentation beyond 36 + 0 weeks' gestation were randomly allo...
Article
Objective: To compare, in women with twin pregnancy with the first twin in cephalic position, neonatal morbidity and mortality rates after planned Ceasarean delivery (CD) versus planned vaginal delivery (VD). Study design: A nationwide cohort study on women pregnant with twins and the first child in cephalic position, who delivered between 32 +...
Article
Full-text available
Background: A number of first-trimester prediction models addressing important obstetric outcomes have been published. However, most models have not been externally validated. External validation is essential before implementing a prediction model in clinical practice. Objective: The objective of this paper is to describe the design of a study t...
Article
Objective: To investigate possible associations between remifentanil and the appearance of sinusoidal heart rate patterns in fetuses, and neonatal outcomes. Methods: The present retrospective cohort study included data from patients at over 37 weeks of singleton or multiple pregnancies attending Zuyderland Medical Center, Sittard, the Netherland...
Article
Cambridge Core - Obstetrics and Gynecology, Reproductive Medicine - Obstetric Interventions - edited by P. Joep Dörr
Article
Introduction: We know a great deal about how childbirth is affected by setting; we know less about how the experience of birth is shaped by the attitudes women bring with them to the birthing room. In order to better understand how women frame childbirth, we examined the relationship between birth place preference and expectations and experiences...
Conference Paper
Background: Fetal Alcohol Spectrum Disorders (FASD) is an umbrella term for one of the leading preventable forms of mental retardation affecting individuals and societies worldwide. Alcohol and its interference with the development of the fetus and child are complex and highly variable. The aim of the present is to assess the current state of the a...
Chapter
In dit hoofdstuk wordt een beschrijving gegeven van de techniek voor het uitvoeren van een keizersnede. Net als bij iedere andere chirurgische ingreep wordt gestreefd naar een techniek waarbij de weefselschade minimaal is, ischemie en ontsteking waar mogelijk worden voorkomen, en adhesievorming zo gering mogelijk is. Hiernaast wordt gestreefd naar...
Article
Full-text available
Purpose of Review The objective of the current contribution is to propose an evidence-based, six-step approach to develop effective programs for prevention of fetal alcohol spectrum disorders. Recent Findings Despite widespread campaigns aimed to reduce prenatal alcohol exposure, the number of affected children continues to be high. Current strate...
Article
Objective To use data from routine sources to compare rates of obstetric intervention in Europe both overall and for subgroups at higher risk of intervention. Design Retrospective analysis of aggregated routine data. Setting Thirty-one European countries or regions contributing data on mode of delivery to the Euro-Peristat project. Population Birth...
Article
Introduction: Large practice variation exists in mode of delivery after cesarean section (CS), suggesting variation in implementation of contemporary guidelines. We aim to evaluate this practice variation and to what extent this can be explained by risk factors at patient level. Material and methods: This retrospective cohort study was performed...
Article
Background: Twin pregnancies are at increased risk for perinatal morbidity and mortality, due to many factors including a high incidence of preterm delivery. Compared to singleton pregnancies overall perinatal mortality risk is higher in twin pregnancies, however for the preterm period perinatal mortality has been reported to be lower in twins. O...
Article
Objective: To assess the cost-effectiveness of routine labour epidural analgesia (EA), from a societal perspective, as compared with labour analgesia on request. Study design: Women delivering of a singleton in cephalic presentation beyond 36+0 weeks' gestation were randomly allocated to routine labour EA or analgesia on request in one universit...
Poster
Fetal Alcohol Spectrum Disorders (FASD) refers to a spectrum of disorders caused by prenatal alcohol consumption. FASD is a neglected problem in the field of Intellectual Disability (ID). Remarkable, because it is hundred percent preventable. Our research focusses on a systematic approach for prevention and clinical management of FASD. The current...
Conference Paper
Full-text available
Background: Fetal Alcohol Spectrum Disorders (FASD) refers to a spectrum of disorders caused by prenatal alcohol consumption. Alcohol consumption during pregnancy and its interference with the development of the fetus and child is complex and highly variable. However, little is known regarding which alcohol consumption patterns most strongly predic...
Conference Paper
Full-text available
Aim: To explore somatic healthcare utilisation patterns among people with intellectual disabilities (ID) 55 years and older living in Sweden in comparison with the general population. Method: The ID group (n = 7936) comprised people with ID who were 55 years and older in 2012. A general population sample (n = 7936) was age- and sexmatched. The samp...
Article
Full-text available
Background: There is an ongoing discussion on the rising CS rate worldwide. Suboptimal guideline adherence may be an important contributor to this rise. Before improvement of care can be established, optimal CS care in different settings has to be defined. This study aimed to develop and measure quality indicators to determine guideline adherence...
Data
Description of stepwise procedure of CS quality indicator development. (DOCX)
Data
Quality indicators on planned CS. (DOCX)
Article
Background: Although fetal alcohol spectrum disorders (FASD) affect communities worldwide, little is known about its prevalence. The objective of this study was to provide an overview of the global FASD prevalence. Methods: We performed a search in multiple electronic bibliographic databases up to August 2015, supplemented with the ascendancy an...
Chapter
In this chapter, we focus on the assessment of the integrity and activity of the fetal central nervous system (CNS). Therefore it is necessary to understand normal behavior and which variables can be used to assess that (e.g., eye and body movements). Furthermore, one needs to understand the (neuro)developmental pathway during gestation, as a “youn...
Chapter
cardio (kardia = hart): met betrekking tot de hartfrequentie toco (tokos = baring): met betrekking tot de baarmoedercontracties grafie (graphein = schrijven): met betrekking tot de afbeelding
Chapter
In dit hoofdstuk wordt de relatie tussen CTG-patronen en het foetale gedrag besproken. Het CTG is uiteraard niets meer dan het registreren van de polsfrequentie in de tijd en het zal duidelijk zijn dat verschillende foetale activiteiten de polsfrequentie zullen beïnvloeden. Pas indien men kennis heeft van het normale foetale gedrag, kan men verschi...
Article
Full-text available
Background: Stillbirth and neonatal mortality rates declined in Europe between 2004 and 2010. We hypothesised that declines might be greater for countries with higher mortality in 2004 and disproportionally affect very preterm infants at highest risk. Methods: Data about live births, stillbirths and neonatal deaths by gestational age (GA) were c...
Article
Full-text available
Most studies on birth settings investigate the association between planned place of birth at the start of labor and birth outcomes and intervention rates. To optimize maternity care it also is important to pay attention to the entire process of pregnancy and childbirth. This study explores the association between the initial preferred place of birt...
Article
Objective: To establish a threshold value for fetal renal pelvis dilatation measured by automatic volume calculation (SonoAVC) in the third trimester of pregnancy to predict neonatal uropathies, and to compare these results with conventional antero-posterior (AP) measurement, fetal kidney 3D volume and renal parenchymal thickness. Methods: In a...
Article
Full-text available
Using orthogonal design, we created a questionnaire containing 16 cases of twin pregnancies. For each case, respondents indicated whether they would plan a vaginal delivery (VD) or a caesarean section (CS). We assessed the association between each variable (maternal age, parity, mode of conception, gestational age, chorionicity, body mass index, fo...
Article
Full-text available
Objective: To identify clinical indicators associated with the planned and actual mode of delivery in women with a twin pregnancy. Study design: We performed a retrospective cohort study in women with a twin pregnancy who delivered at a gestational age of 32+0-41+0 weeks and days between 2000 and 2008 in the Netherlands. Data were obtained from...
Conference Paper
Full-text available
Background: Alcohol use during pregnancy is one of the leading preventable causes of intellectual or developmental disability. This situation clearly warrants intervention. The complexity of intervention development concerning FASD is overlooked in health promotion. Evidence-based health promotion intervention aimed at the field of FASD is a comple...
Article
Full-text available
Samenvatting De ontwikkeling van het ongeboren kind kan ernstig in gevaar worden gebracht door alcoholgebruik tijdens de zwangerschap. Deze prenatale blootstelling aan alcohol kan leiden tot levenslange lichamelijke afwijkingen, gedragsstoornissen en cognitieve beperkingen. De Foetaal Alcohol Spectrum Stoornis (FASD) treft alle samenlevingen en is...
Conference Paper
Background: Alcohol use during pregnancy is one of the leading preventable causes of intellectual or developmental disability. FASD is the non-diagnostic umbrella term used to characterize the full range of damage caused by prenatal alcohol exposure, varying from mild to severe, and encompassing a broad array of physical defects and cognitive, beha...
Article
Objective The aim of the study was to assess the impact of gestational age (GA) at rupture and latency on perinatal outcome after midtrimester prelabor rupture of membranes (PROM). Study Design We obtained data on singleton pregnancies from 22 weeks onwards from the Dutch Perinatal Registry from 1999 to 2007, congenital abnormalities were excluded....
Article
In de verloskunde wordt het steeds duidelijker dat een groot gedeelte van de complicaties of aangeboren en verworven afwijkingen kan worden voorkomen indien een vrouw en haar partner, wanneer zij stoppen met het gebruik van anticonceptie met het doel zwanger te worden, zich optimaal informeren over preventieve maatregelen. Het preconceptioneel advi...
Article
Als het gaat om het voorschrijven van medicatie heeft de gemiddelde arts veelal een ‘heilig ontzag’ voor zwangerschap. Dit betekent dat veel artsen terughoudend zijn met het voorschrijven van medicijnen, ook in die gevallen waar het wel geïndiceerd is. De eerste vraag is of de zwangere vrouw een aandoening heeft die je zou behandelen als ze niet zw...
Article
To use data from routine sources to compare rates of obstetric intervention in Europe both overall and for subgroups at higher risk of intervention. Retrospective analysis of aggregated routine data. Thirty-one European countries or regions contributing data on mode of delivery to the Euro-Peristat project. Births in participating countries in 2010...
Article
Full-text available
To compare the incidence of perinatal mortality and morbidity between planned home versus planned hospital births among low-risk women in midwife-led care at the onset of labour. A nationwide cohort study. Retrospective analysis of data from 3 nationwide registries over the years 2000-2009. Main outcome measures were intrapartum and neonatal death,...
Article
Full-text available
Background While international variations in overall cesarean delivery rates are well documented, less information is available for clinical sub-groups. Cesarean data presented by subgroups can be used to evaluate uptake of cesarean reduction policies or to monitor delivery practices for high and low risk pregnancies based on new scientific evidenc...
Article
Objective To compare rates of adverse perinatal outcomes between planned home births versus planned hospital births. DesignA nationwide cohort study. SettingThe Netherlands. PopulationLow-risk women in midwife-led care at the onset of labour. Methods Analysis of national registration data. Main outcome measuresIntrapartum and neonatal death, Apgar...
Article
Objective: To compare the change in foetal and neonatal mortality in the Netherlands between 2004 and 2010 with the change in other European countries. Design: Descriptive, population-based study. Method: Data from the Euro-Peristat project on foetal and neonatal mortality in European countries were analysed for changes between 2004 and 2010....
Article
Full-text available
Objective To assess the effect on mode of delivery of the routine use of labour epidural analgesia (EA) compared with analgesia on request.DesignRandomised non-inferiority trial.SettingOne university and one non-university teaching hospital in The Netherlands.PopulationWomen with a singleton pregnancy in cephalic presentation beyond 36 + 0 weeks' g...
Article
Objective Women with late preterm premature rupture of membranes (PROM) have an increased risk that their child will develop neonatal sepsis. We evaluated whether neonatal sepsis can be predicted from antepartum parameters in these women. Study design: We used multivariable logistic regression to develop a prediction model. Data were obtained from...
Article
Full-text available
Compared with other countries, the elective caesarean section rate for twins is relatively low in the Netherlands. Worldwide, there is an increasing trend toward performing more elective caesarean sections for women with a twin pregnancy at term, be it for twins with the first child in breech or in cephalic presentation. The results of the 'Twin Bi...
Article
As part of the move toward "patient-centered care," women's preferences with regard to maternity services have become increasingly important to policy makers. To realize optimal patient-centered care, knowledge of patients' preferences is essential. The aim of our study was to assess the strength and relative importance of women's preferences for d...
Article
Full-text available
Babies born after midtrimester preterm prelabour rupture of membranes (PPROM) are at risk to develop neonatal pulmonary hypoplasia. Perinatal mortality and morbidity after this complication is high. Oligohydramnios in the midtrimester following PPROM is considered to cause a delay in lung development. Repeated transabdominal amnioinfusion with the...
Article
Full-text available
Objective To compare the costs of induction of labor and expectant management in women with preterm prelabor rupture of membranes (PPROM). DesignEconomic analysis based on a randomized clinical trial. SettingObstetric departments of eight academic and 52 non-academic hospitals in the Netherlands. PopulationWomen with PPROM near term who were not in...
Article
To externally validate two models from the USA (entry-to-care [ETC] and close-to-delivery [CTD]) that predict successful intended vaginal birth after caesarean (VBAC) for the Dutch population. A nationwide registration-based cohort study. Seventeen hospitals in the Netherlands. Seven hundred and sixty-three pregnant women, each with one previous ca...
Article
Full-text available
To develop and internally validate a model that predicts the outcome of an intended vaginal birth after caesarean (VBAC) for a Western European population that can be used to personalise counselling for deliveries at term. Registration-based retrospective cohort study. Five university teaching hospitals, seven non-university teaching hospitals, and...
Article
To develop a patient decision aid (PtDA) for mode of delivery after caesarean section that integrates personalised prediction of vaginal birth after caesarean (VBAC) with the elicitation of patient preferences and evidence-based information. A PtDA was developed and pilot tested using the International Patients Decision Aid Standards (IPDAS) criter...
Article
There is controversy on the preferred mode of delivery (vaginal delivery (VD) versus caesarean section (CS)) in preterm breech delivery in relation to neonatal outcome. While CS is supposed to be safer for the fetus, arguments against CS can be the increased risk of maternal morbidity, risks for future pregnancies, and costs. Moreover, neonatal res...
Article
Full-text available
Objective Midtrimester preterm prelabor rupture of membranes (PPROM) has a high rate of neonatal mortality and morbidity. The aim of this study was to study outcomes of subsequent pregnancies after a pregnancy with PPROM before 27 weeks' gestation. Study Design Retrospective study of subsequent pregnancies of women who suffered PPROM before 27 week...