Jan B. Engelmann

University of Amsterdam | UVA · Department of Economics

Aversive emotions are likely to be a key source of irrational human decision-making but still little is known about the underlying neural circuitry. Here, we show that aversive emotions distort trust decisions and cause significant changes in the associated neural circuitry. They reduce trust and suppress trust-specific activity in left temporopari...

Background Commonly observed distortions in decision-making among patients with major depressive disorder (MDD) may emerge from impaired reward processing and cognitive biases toward negative events. There is substantial theoretical support for the hypothesis that MDD patients overweight potential losses compared with gains, though the neurobiologi...

Significance Using an interdisciplinary experimental approach grounded in behavioral economics and personality psychology, we identify an antisocial personality profile and examine its role across strategic contexts. Antisocial individuals exhibit a specific combination of behaviors and beliefs: they have a high propensity to betray others’ trust a...

The ability to correctly estimate the probability of one’s choices being correct is fundamental to optimally re-evaluate previous choices or to arbitrate between different decision strategies. Experimental evidence nonetheless suggests that this metacognitive process—confidence judgment- is susceptible to numerous biases. Here, we investigate the e...

We investigate the role of visual attention in risky choice in a rich experimental dataset that includes eye-tracking data. We first show that attention is not reducible to individual and contextual variables, which explain only 20% of attentional variation. We then decompose attentional variation into individual average attention and trial-wise de...

Reorientation of attention to threatening stimuli is a fundamental part of human cognition. Such interaction between cognitive and affective processes is often associated with faster response times. In the present study the role of the right angular gyrus (AG) in reorienting to threat is examined. An exogenous spatial cueing paradigm was adopted wi...

Humans need social closeness to prosper. There is evidence that empathy can induce social closeness. However, it remains unclear how empathy-related social closeness is formed and how stable it is as time passes. We applied an acquisitionextinction paradigm combined with computational modeling and fMRI, to investigate the formation and stability of...

Sustainability ratings help consumers understand the environmental impact of their purchases. Such ratings have increased the consumers' sustainable choices in the electrodomestics and housing markets. In the particular case of energy labels, sustainable products are also associated with private benefits due to future cost reductions in energy expe...

Across five experiments (N = 1,714), we test whether people engage in wishful thinking to alleviate anxiety about adverse future outcomes. Participants perform pattern recognition tasks in which some patterns may result in an electric shock or a monetary loss. Diagnostic of wishful thinking, participants are less likely to correctly identify patter...

When someone violates a social norm, others may think that some sanction would be appropriate. We examine how the experience of emotions like anger and disgust relate to the judged appropriateness of sanctions, in a pre-registered analysis of data from a large-scale study in 56 societies. Across the world, we find that individuals who experience an...

While the effects of anxiety on various cognitive processes, including memory, attention, and learning, have been relatively well documented, the neurobiological effects of anxiety on social cognitive processes remain largely unknown. We address this gap using threat-of-shock to induce incidental anxiety while participants performed two false-belie...

The emergence of COVID-19 dramatically changed social behavior across societies and contexts. Here we study whether social norms also changed. Specifically, we study this question for cultural tightness (the degree to which societies generally have strong norms), specific social norms (e.g. stealing, hand washing), and norms about enforcement, usin...

While navigating a fundamentally uncertain world, humans and animals constantly evaluate the probability of their decisions, actions or statements being correct. When explicitly elicited, these confidence estimates typically correlates positively with neural activity in a ventromedial-prefrontal (VMPFC) network and negatively in a dorsolateral and...

Background and aims: People with Gambling Disorder (GD) often make risky decisions and experience cognitive distortions about gambling. Moreover, people with GD have been shown to be overly confident in their decisions, especially when money can be won. Here we investigated if and how the act of making a risky choice with varying monetary stakes i...

While the effects of anxiety on various cognitive processes, including memory, attention, and learning, have been relatively well documented, the neurobiological effects of anxiety on social cognitive processes remain largely unknown. We address this gap using threat-of-shock to induce incidental anxiety while participants performed two false-belie...

Studies in Social Neuroeconomics have consistently reported activation in social cognition regions during interactive economic games suggesting mentalizing during economic choice. Such mentalizing occurs during active participation of the game, as well as during passive observation of others' interactions. We designed a novel version of the classic...

While navigating a fundamentally uncertain world, humans and animals constantly produce subjective confidence judgments, thereby evaluating the probability of their decisions, actions or statements being correct. Confidence typically correlates with neural activity positively in a ventromedial-prefrontal (VMPFC) network and negatively in a dorsolat...

Humans need social closeness to prosper. There is evidence that empathy can induce social closeness. However, it remains unclear how empathy-related social closeness is formed and how stable it is as time passes. Here we applied an acquisition-extinction paradigm, combined with computational modelling and fMRI, to investigate the formation and stab...

Gambling disorder (GD) is a behavioural addiction characterized by impairments in decision-making, favouring risk- and reward-prone choices. One explanatory factor for this behaviour is a deviation in attentional processes, as increasing evidence indicates that GD patients show an attentional bias toward gambling stimuli. However, previous attentio...

Gambling disorder (GD) is a behavioural addiction characterized by impairments in decision-making, favouring risk- and reward-prone choices. One explanatory factor for this behaviour is a deviation in attentional processes, as increasing evidence indicates that GD patients show an attentional bias toward gambling stimuli. However, previous attentio...

Although cooperation can lead to mutually beneficial outcomes, cooperative actions only pay off for the individual if others can be trusted to cooperate as well. Identifying trustworthy interaction partners is therefore a central challenge in human social life. How do people navigate this challenge? Prior work suggests that people rely on facial ap...

Nielsen et al. (1) argue that Van Doesum et al. (2) need to consider three points for their interpretation of a positive association between individual-level social mindfulness (SoMi) and environmental performance (EPI) at the country level (3). The association is weaker when 1) it is controlled for GDP and 2) when the data of three countries are r...

Studies in Social Neuroeconomics have consistently reported activation in social cognition regions during interactive economic games suggesting mentalizing during economic choice. It remains important to test the involvement of neural activity associated with mentalizing in an economic games context within the same sample of participants performing...

Trust is essential for establishing and maintaining cooperative behaviors between individuals and institutions in a wide variety of social, economic, and political contexts. This book explores trust through the lens of neurobiology, focusing on empirical, methodological, and theoretical aspects. Written by a distinguished group of researchers from...

Anxiety is a common affective state, characterized by the subjectively unpleasant feelings of dread over an anticipated event. Anxiety is suspected to have important negative consequences on cognition, decision-making, and learning. Yet, despite a recent surge in studies investigating the specific effects of anxiety on reinforcement-learning, no co...

Humans are social animals, but not everyone will be mindful of others to the same extent. Individual differences have been found, but would social mindfulness also be shaped by one’s location in the world? Expecting cross-national differences to exist, we examined if and how social mindfulness differs across countries. At little to no material cost...

Norm enforcement may be important for resolving conflicts and promoting cooperation. However, little is known about how preferred responses to norm violations vary across cultures and across domains. In a preregistered study of 57 countries (using convenience samples of 22,863 students and non-students), we measured perceptions of the appropriatene...

Although cooperation can lead to mutually beneficial outcomes, cooperating only pays off for the individual if others can be trusted to cooperate as well. How do people detect trustworthy interaction partners? While people readily rely on the facial appearance of strangers to judge their trustworthiness, the question of whether these judgments are...

In simple instrumental-learning tasks, humans learn to seek gains and to avoid losses equally well. Yet, two effects of valence are observed. First, decisions in loss-contexts are slower. Second, loss contexts decrease individuals’ confidence in their choices. Whether these two effects are two manifestations of a single mechanism or whether they ca...

Anxiety is a common affective state, characterized by the subjectively unpleasant feelings of dread over an anticipated event. Anxiety is suspected to have important negative consequences on cognition, decision-making and learning. Yet, despite a recent surge in studies investigating the specific effects of anxiety on reinforcement-learning, no coh...

Background and objectives: Although approaches combining behavioral genetics and neuroeconomics have advanced models of addiction, no study has synthesized these methods to elucidate mechanisms of competing risk-approachand risk-avoidance in social anxiety (SA). Grounded in dual-mode models of serotonergic systems and self-regulation, this study in...

Our behavior is constantly accompanied by a sense of confidence and its’ precision is critical for adequate adaptation and survival. Importantly, abnormal confidence judgments that do not reflect reality may play a crucial role in pathological decision-making typically seen in psychiatric disorders. In this review, we propose abnormalities of confi...

In simple probabilistic instrumental-learning tasks, humans learn to seek reward and to avoid punishment equally well. Despite this remarkable symmetry in choice accuracy between gain and loss contexts, two recent effects of valence have been independently documented in reinforcement learning. First, decisions in a loss-context are slower, which is...

Our behavior is constantly accompanied by a sense of confidence. Its precision is critical for adequate adaption and survival. Inaccurate confidence judgments may result in pathological decision-making and eventually in psychiatric disorders. In this review, we propose abnormalities of confidence as a new model of interpreting psychiatric symptoms....

We assess the role of anti-social personality traits in explaining heterogeneity in commonly observed social preferences. We identified a personality profile that clearly reflects anti-social personality characteristics, with high positive loadings on Machiavellianism and high negative loadings on empathy, trustworthiness and agreeableness. Anti-so...

We are often presented with choices that differ in their more immediate versus future consequences. Interestingly, in everyday-life, ambiguity about the exact timing of such consequences frequently occurs, yet it remains unknown whether and how time-ambiguity influences decisions and their underlying neural correlates. We developed a novel intertem...

Pain feels different in different social contexts, yet the mechanisms behind social pain modulation remain poorly understood. To elucidate the impact of social context on pain processing, we investigated how group member- ship, one of the most important social context factors, shapes pain relief behaviourally and neurally in humans undergoing funct...

The ability to correctly estimate the probability of one's choices being correct is fundamental to optimally re-evaluate previous choices or to arbitrate between different decision strategies. Experimental evidence nonetheless suggests that this metacognitive process -referred to as a confidence judgment- is susceptible to numerous biases. We inves...

Aversive emotions are likely to be a key source of irrational human decision-making but still little is known about the neural circuitry underlying emotion-cognition interactions during social behavior. Here, we show that incidental aversive emotions distort trust decisions and cause significant changes in the associated neural circuitry. Experimen...

The right posterior parietal cortex (PPC) is implicated in spatial attention, but its specific role in emotional spatial attention remains unclear. In this study, we combined inhibitory transcranial magnetic stimulation (TMS) with a fear-conditioning paradigm to test the role of the right PPC in attentional control of task-irrelevant threatening di...

The ability to read emotions from faces is a very important skill. One might even call it a superpower. People around the world use this skill when they communicate with each other. But do people from different cultural backgrounds recognize and interpret facial expressions the same way? The answer, according to scientists, is both yes and no. Yes,...

Aversive emotions are likely to be a key source of irrational human decision-making but still little is known about the underlying neural circuitry. Here, we show that aversive emotions distort trust decisions and cause significant changes in the associated neural circuitry. They reduce trust and suppress trust-specific activity in left temporopari...

We present recent evidence supporting the idea that emotions promote specific behaviors in an organism and that incidental emotion or affective cues will bias choices towards actions consistent with those behavioral goals. We review several strands of research in psychology, economics, and neuroscience showing that different emotions and mood state...

The right posterior parietal cortex (PPC) is implicated in spatial attention, but its specific role in emotional spatial attention remains unclear. In the present study, we combined inhibitory transcranial magnetic stimulation (TMS) with a fear conditioning paradigm to test the role of the right PPC in attentional control of task-irrelevant threate...

Recent experiments suggest that dishonesty can escalate from small levels to ever-larger ones along a ‘slippery slope’. Activity in bilateral amygdala tracks this gradual adaptation to repeated acts of self-serving dishonesty.

There is accumulating evidence suggesting that emotions can have a strong impact on social decision-making. However, the neural mechanisms of emotional influences on choice are less well understood to date. Here, we integrate recent results from two independent, but related, research streams in Social Neuroeconomics and Social Neuroscience, which t...

Significance Deficits in empathy for out-group members are pervasive, with negative societal impact. It is therefore important to ascertain whether empathy toward out-groups can be learned and how learning experiences change empathy-related brain responses. We used a learning intervention during which participants experienced help from a member of...

Incidental negative emotions unrelated to the current task, such as background anxiety, can strongly influence decisions. This is most evident in psychiatric disorders associated with generalized emotional disturbances. However, the neural mechanisms by which incidental emotions may affect choices remain poorly understood. Here we study the effects...

A key ingredient of many popular asset pricing models is that investors exhibit countercyclical risk aversion, which helps explain major puzzles in financial economics such as the strong and systematic variation in risk premiums over time and the high volatility of asset prices. There is, however, surprisingly little evidence for this assumption be...

Background: Depression is a prevalent disorder that significantly affects the social functioning and interpersonal relationships of individuals. This highlights the need for investigation of the neural mechanisms underlying these social difficulties. Investigation of social exchanges has traditionally been challenging as such interactions are diff...

Objective: Distortions in decision-making are common among patients with major depressive disorder (MDD) and can lead to substantial negative life consequences. Little is known about how the neural computations underlying valuation of potential gains and losses are altered in patients with MDD compared to healthy control (HC) subjects. A component...

Human and nonhuman animals respond asymmetrically to predicted punishments and rewards (Dayan & Seymour, 2008; Kahneman, 2011). In human decision making, for example, people pay more to avoid losses than to gain equivalent rewards. Because such loss aversion counterproductively diminishes an individual’s expected payoffs, it has become one of the m...

Although both attention and motivation affect behavior, how these 2 systems interact is currently unknown. To address this question, 2 experiments were conducted in which participants performed a spatially cued forced-choice localization task under varying levels of motivation. Participants were asked to indicate the location of a peripherally cued...

Decisions under risk and with outcomes that are delayed in time are ubiquitous in real life and can have a significant impact on the health and wealth of the decision-maker. Despite its potential relevance for real-world choices, the degree of aberrant risky and intertemporal decision-making in patients suffering from major depressive disorder (MDD...

There are two regularities we have learned from experimental studies of choice under risk. The first is that the majority of people weigh objective probabilities nonlinearly. The second regularity, although less commonly acknowledged, is that there is a large amount of heterogeneity in how people distort probabilities. Despite this, little effort h...

Despite consistently documented cultural differences in the perception of facial expressions of emotion, the role of culture in shaping cognitive mechanisms that are central to emotion perception has received relatively little attention in past research. We review recent developments in cross-cultural psychology that provide particular insights int...

To survive in our complex environment, we have to adapt to changing contexts. Prior research that investigated how contextual changes are processed in the human brain has demonstrated important modulatory influences on multiple cognitive processes underlying decision-making, including perceptual judgments, working memory, as well as cognitive and a...

We investigated behavioral and neurobiological mechanisms by which risk-averse advice, provided by an expert, affected risky decisions across three developmental groups [early adolescents (12-14 years), late adolescents (15-17 years), adults (18+ years)]. Using cumulative prospect theory, we modeled choice behavior during a risky-choice task. Resul...