Jamie Seymour

Jamie Seymour
James Cook University Brisbane · AITHM

BSc (Hon) PhD

About

164
Publications
42,951
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
3,235
Citations
Citations since 2016
49 Research Items
1641 Citations
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250
2016201720182019202020212022050100150200250
Additional affiliations
June 2012 - present
JAmes Cook University Cairns
Position
  • JAmes Cook University
January 2002 - June 2012
James Cook University Brisbane

Publications

Publications (164)
Article
Full-text available
Understanding the links between species and their environment is critical for species management. This is particularly true for organisms of medical and/or economic significance. The 'Irukandji' jellyfish (Carukia barnesi) is well known for its small size, cryptic nature, and highly venomous sting. Being the namesake of the Irukandji syndrome, cont...
Article
Full-text available
Here we utilize chemical ecology as a tool to manipulate the biological system of a small, but highly venomous to humans, cubozoan jellyfish, Carukia barnesi. We trialled a range of chemical reagents including indole compounds, 9-cis-retinoic acid and lugols solution to induce metamorphosis between the polyp and medusa life stages. An optimum metho...
Article
Objective: Irukandji syndrome (IS) is an extremely painful condition that causes a significant catecholamine surge and sympathetic autonomic response related to the envenomation from certain types of jellyfish. Current management involves intravenous fluids, magnesium sulphate and large doses of opioids for symptom control. Clonidine, a centrally...
Article
Full-text available
This paper presents a new mode of asexual reproduction of Ricordea yuma. Seventeen instances of tentacle autotomy (the deliberate shedding of tentacles) were observed in the tropical corallimorpharian, Ricordea yuma, over a four-month period. Of these, seven were deemed to have successfully completed transformation into polyps complete with mouth a...
Article
Full-text available
Cnidarian bleaching research often focuses on the effects on a cnidarian's physiological health and fitness, whilst little focus has been towards the impacts of these events on their venom ecology. Given the importance of a cnidarian's venom to their survival and the increasing threat of bleaching events, it is important to understand the effects t...
Poster
Full-text available
Here we utilize chemical biology as a tool to manipulate the biological system of a small, but highly venomous to humans, cubozoan jellyfish, Carukia barnesi. We trialled a range of chemical reagents including indole compounds, 9-cis-retinoic acid and lugols solution to induce metamorphosis between the polyp and medusa life stages. An optimum metho...
Article
Full-text available
Sawfishes are among the most threatened families of marine fishes and are susceptible to incidental capture in net fisheries. Since bycatch reduction devices currently used in trawl fisheries are not effective at reducing sawfish catches, new methods to minimise sawfish bycatch are needed. Ideally, these should affect sawfish behaviour and prevent...
Article
Full-text available
Stonefish are regarded as one of the most venomous fish in the world. Research on stone-fish venom has chiefly focused on the in vitro and in vivo neurological, cardiovascular, cytotoxic and nociceptive effects of the venom. The last literature review on stonefish venom was published over a decade ago, and much has changed in the field since. In th...
Article
Full-text available
Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the consequences of envenomation range from self-limiting to lethal. Critical host defence against envenomation comprises innate and adaptive immune strategies targeted towards venom detection, neutralisation, detoxification, and symptom resolution. In some instan...
Article
Full-text available
Venom research is often focussed on medical relevance, novel compounds and venom evolution, whilst studying the relationship between a venom and its environment – venom ecology - has been conducted to a lesser extent. Given the projected environmental changes envisioned to occur with global warming, it is pertinent now more than ever, to highlight...
Article
Cherax quadricarinatus (redclaw) aquaculture has not achieved the industry growth that had been predicted in the early days of development. Provision of quality juvenile crayfish seed stock has been identified as a critical factor in overcoming industry development inertia. Hatchery technology has been developed to produce independent craylings and...
Article
Redclaw, Cherax quadricariatus (von Martens) has shown promise as an aquaculture species but commercial development has been constrained by variability of production, perhaps due to poor survival and growth of early craylings. Diet contributes to survival and growth and previous studies have determined requirements for larger redclaw, but little re...
Article
Modern, intensified aquaculture typically involves three production phases; hatchery, nursery, and grow-out. For redclaw crayfish aquaculture however, such delineation has been ill-defined. Farming of redclaw was initiated based on the putative beneficial physical and biological attributes of the species, which suggested production methods would be...
Article
Full-text available
Carukia barnesi was the first in an expanding list of cubozoan jellyfish whose sting was identified as causing Irukandji syndrome. Nematocysts present on both the bell and tentacles are known to produce localised stings, though their individual roles in Irukandji syndrome have remained speculative. This research examines differences through venom p...
Article
Full-text available
Biological investigations on free ranging marine species are regarded as challenging throughout the scientific community. This is particularly true for 'logistically difficult species' where their cryptic natures, low abundance, patchy distributions and difficult and/or dangerous sampling environments, make traditional surveys near impossible. What...
Article
The emergence of novel venom extraction techniques over the last half-century has greatly facilitated advances in the field of cnidarian research. A new recovery protocol utilizing ethanol as the primary stimulant in nematocyst discharge was recently published, however in vitro examination of the venom on organic models was not performed. This pres...
Article
Both Chironex fleckeri venom (CFV) and Carukia barnesi venoms (CBV) are known to cause significant cardiac morbidity and mortality. Many animal studies have demonstrated cardiac dysfunction with these venoms. This study specifically examines the systolic and diastolic cardiac functions using non-invasive pulse wave doppler. Mitral and aortic dopple...
Article
Full-text available
Pupillary response under varying conditions of bright light and darkness was compared in three species of Cubozoa with differing ecologies. Maximal and minimal pupil area in relation to total eye area was measured and the rate of change recorded. In Carukia barnesi, the rate of pupil constriction was faster and final constriction greater than in Ch...
Article
The Australian Redclaw crayfish, Cherax quadricarinatus, has been the subject of aquaculture development for more than 3 decades. Farm production from Australia and from around the world for this species has been relatively low, as suitable production technology continues to develop. The production of redclaw juveniles for the purpose of stocking t...
Article
Full-text available
The box jellyfish Chironex fleckeri is extremely venomous, and envenoming causes tissue necrosis, extreme pain and death within minutes after severe exposure. Despite rapid and potent venom action, basic mechanistic insight is lacking. Here we perform molecular dissection of a jellyfish venom-induced cell death pathway by screening for host compone...
Article
Safety considerations for researchers shape ecological research approaches in dangerous aquatic environments. A series of recent studies has demonstrated that the moray Gymnothorax polyuranodon (Family Muraenidae) occupies freshwater in the adult phase. However, its potential use of tidal habitat remains largely unexplored, due partly to the challe...
Article
Full-text available
This research presents the early life history stages of Malo maxima, a recently described tropical Australian cubozoan from the family Carukiidae, from sexual fertilisation to metamorphosis including planula, polyp, asexual reproductive strategies and young medusa. We discuss the similarities between M. maxima and two closely related carukiid speci...
Article
Full-text available
The Australian jellyfish Chironex fleckeri, belongs to a family of cubozoan jellyfish known for their potent venoms. CfTX-1 and -2 are two highly abundant toxins in the venom, but there is no structural data available for these proteins. Structural information on toxins is integral to the understanding of the mechanism of these toxins and the devel...
Article
Full-text available
Organisms embedded within food webs must balance arms races with their predators and prey. For venom users, venom may mediate each arms race, but the dynamical evolutionary changes in venom production in response to the two arms races are still poorly understood. Here, we use a simple model to evaluate the evolutionary response of a venomous consum...
Article
Two new species of myxosporeans are described from the gall bladders of Estuarine Stonefish, Synanceia horrida, and Reef Stonefish, Synanceia verrucosa, from localities off Cairns, in tropical north Queensland (QLD) and in Moreton Bay in southern QLD, Australia. Sphaeromyxa horrida n. sp. can be distinguished from congeners in the morphologically d...
Article
For the first time the impedance-based xCELLigence real-time cell analysis system was used to measure the myotoxicity of sea snake venom. With a focus on the spine-bellied sea snake (Hydrophis curtus), the venom of four sea snake species and three terrestrial snake species were compared for myotoxicity against a human skeletal muscle cell line (HSk...
Article
Full-text available
The spine-bellied sea snake (Hydrophis curtus) is known to cause human deaths, yet its venom composition has not yet been proteomically characterised. An indepth proteomic analysis was performed on H. curtus venom from two different seasons, January and June, corresponding to adults and subadults, respectively. Venoms from adult and subadult H. cur...
Article
Animals embedded between trophic levels must simultaneously balance pressures to deter predators and acquire resources. Venomous animals may use venom toxins to mediate both pressures, and thus changes in this balance may alter the composition of venoms. Basic theory suggests that greater exposure to a predator should induce a larger proportion of...
Article
Objectives: To investigate the effects of temperature and hot water immersion time on neutralising venom lethality of the Australian estuarine stonefish (Synanceia horrida). Design: Depths of the spines were measured while venom was extracted from S. horrida individuals. The venom was then exposed to temperatures of 4°C, 37.0°C, 40.1°C, 42.3°C,...
Article
Full-text available
The answer is predicated on our knowing what the correct treatment is — and we don’t © 2017 AMPCo Pty Ltd. Produced with Elsevier B.V. All rights reserved.
Article
Currently the Australian Resuscitation Council (ARC) recommends dousing with vinegar followed by ice as first aid for jellyfish stings in tropical Australia, with limited evidence to support this recommendation (Li et al., 2013). We report our successful experience in using hot water immersion as first aid in treating two people stung by venomous t...
Article
Full-text available
Seagrasses are an important component of the marine ecosystems of Singapore. Using various assessment activities, we confirm 10 seagrass species within the waters of Singapore, with an additional two species under review for synonymy. Using long-term monitoring we examined the key attributes that affect the resilience of Singapore's seagrasses. We...
Article
Full-text available
This research explores the thermal and osmotic tolerance of the polyp stage of the Irukandji jellyfish Carukia barnesi, which provides new insights into potential polyp habitat suitability. The research also targets temperature, salinity, feeding frequency, and combinations thereof, as cues for synchronous medusae production. Primary findings revea...
Data
Carukia barnesi Polyp Count Data Associated With “Effects of Feeding Frequency on Survivorship and Asexual Reproduction”. Variable list/description: Sample identification number; Time (weeks) (e.g., Time 0 indicates start of experiment and Times 1–6 indicate after 1–6 weeks; Well number; Temperature (°C); Salinity (‰);Total (total number of polyps...
Data
Carukia barnesi Polyp Count Data Associated With “Thermal and Osmotic Effects on Survivorship and Asexual Reproduction”. Variable list/description: Sample identification number; Well number; Treatment number; Temperature (°C); Salinity (‰); Time (weeks) (e.g., Time 0 indicates start of experiment and Time 6 indicates after 6 weeks; Total (total num...
Data
The R Code Used for Analysis of “Thermal and Osmotic Effects on Survivorship and Asexual Reproduction”. (TXT)
Data
Mean Values and Standard Errors of the Number of Polyps Present after Six Weeks Exposure to a Matrix of Eight Temperatures and Ten Salinity Treatments. All values were calculated as the relative change in polyp density and are presented as proportional change, where values above one indicate population increase through asexual reproduction and valu...
Article
Full-text available
Flagship species, especially mammals and birds, are commonly used to increase awareness of conservation issues in marine and terrestrial ecosystems. However, flagship species oriented programs are often ad hoc with initiatives scarce in the freshwater context. Here, we aim to identify potential flagship candidates that would appeal to a broad cross...
Article
Full-text available
Adult medusae of Carukia barnesi were collected near Double Island, North Queensland Australia. From 73 specimens, 8 males and 15 females spawned under laboratory conditions. These gametes were artificially mixed which resulted in fertilized eggs. Post fertilization, most eggs developed to an encapsulated planula stage and then paused for between s...
Chapter
Within the marine realm there are many organisms that produce toxins, some of which are cardiotoxic to human beings. They exhibit their toxicity at both cellular and molecular levels, often via channelopathy. Arguably, cnidarians are the most venomous, capable of causing cardiac complications within a few minutes of envenomation. However, marine to...
Article
Full-text available
Significance Here, we present the structure of the pore-forming toxin stonustoxin (SNTX), the lethal factor present in stonefish venom. Our work shows that SNTX comprises two homologous subunits (α and β), each of which belongs to the perforin superfamily of pore-forming immune effectors. In SNTX, the α- and β-Membrane Attack Complex-Perforin/Chole...
Article
Full-text available
Adult Carukia barnesi medusae feed predominantly on larval fish; however, their mode of prey capture seems more complex than previously described. Our findings revealed that during light conditions, this species extends its tentacles and 'twitches' them frequently. This highlights the lure-like nematocyst clusters in the water column, which activel...
Article
Body size is a key determinant of metabolic rate, but logistical constraints have led to a paucity of energetics measurements from large water-breathing animals. As a result, estimating energy requirements of large fish generally relies on extrapolation of metabolic rate from individuals of lower body mass using allometric relationships that are no...
Article
Full-text available
The primary aim of this study was to identify aquatic invertebrate predators of amphibian eggs and tadpoles in an area of South Australia. The presence and abundance of aquatic invertebrates was monitored at four field sites for a period of 5-6 months; this revealed notonectids, freshwater crayfish and odonates to be amongst the most common inverte...
Article
Full-text available
The venom of certain jellyfish has long been known to be potentially fatal to humans, but it is only recently that details of the proteomes of these fascinating creatures are emerging. The molecular contents of the nematocysts from several jellyfish species have now been analyzed using proteomic MS approaches and include the analysis of Chironex fl...
Article
Full-text available
Background The effectiveness of the currently available box jellyfish (Chironex fleckeri) antivenom has been subject of debate for many years. To assess whether the box jellyfish antivenom has the ability to attenuate venom-induced damage at cellular level, the present study analyzed the dose and time dependence of the antivenom in a cell-based ass...
Article
We thank Drs Gibbs, Corkeron and Blake for their interest in our study. We are delighted to respond to their comments. Firstly, the anecdote that vinegar increases pain and an unpublished case series (into analgesic requirements in Irukandji envenomation) performed at Cairns Hospital concerned us that vinegar may not be the panacea it is thought to...
Article
To determine the effect acetic acid (vinegar) has on discharged nematocysts in a simulated sting from Chironex fleckeri. This research was performed in 2 parts: 1 C. fleckeri tentacles placed on amniotic membrane were electrically stimulated, and venom washings collected before and after application of vinegar. Lyophilised venom washings were run t...
Article
The vertebrate cardiotoxic components of the venom produced by the Australian box jellyfish, Chironex fleckeri, have not previously been isolated. We have uncovered for the first time, three distinct cytotoxic crude fractions from within the vertebrate cardiotoxic peak of C. fleckeri venom by monitoring viability of human muscle cells with an imped...
Article
Full-text available
The early life stages of the cubomedusa Alatina cf. moseri from Osprey Reef (North Queensland, Australia) and Waikiki (Oahu, Hawaii) were studied using laboratory-based culturing conditions. Spawning populations from both regions were observed with reliable periodicity allowing polyp cultures from these locations to be collected and established und...
Article
Full-text available
The box jellyfish Chironex fleckeri produces extremely potent and rapid-acting venom that is harmful to humans and lethal to prey. Here, we describe the characterization of two C. fleckeri venom proteins, CfTX-A (∼40 kDa) and CfTX-B (∼42 kDa), which were isolated from C. fleckeri venom using size exclusion chromatography and cation exchange chromat...
Article
Full-text available
Increasing ocean temperatures and strengthening boundary currents have caused the poleward migration of many marine species. Cubozoan jellyfish known to cause Irukandji syndrome have historically been confined to tropical waters but may be expanding into subtropical regions. Here, we examine the interactive effects of warming and acidification on t...
Article
Although Chironex fleckeri and Carukia barnesi cause significant human envenomation, research into their effects in human models or human cells has been limited. In this in vitro study we have presented data that shows that although C. fleckeri is highly cytotoxic to human cardiac and skeletal muscle cells, C. barnesi is not cytotoxic at all concen...
Article
Full-text available
A latina nr mordens have been located in large predictable spawning aggregations near Osprey Reef in the Coral Sea eight to ten days after a full moon; however, polyps have never been located in-situ. The polyp stage contributes to the abundance of medusae through asexual reproduction and metamorphosis, and may influence the periodicity of medusae...