James Loock

James Loock
Stellenbosch University | SUN · Division of Otorhinolaryngology

About

30
Publications
2,140
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
185
Citations

Publications

Publications (30)
Article
Objective Limited data on the prevalence of human papilloma virus (HPV)–positive oropharyngeal squamous cell carcinoma (OPSCC) in Southern Africa exist. The aim of the current study was to determine the prevalence of HPV-positive OPSCC at a major referral public hospital (Tygerberg Hospital) in the Western Cape region, South Africa. Methods Sequen...
Article
Stridor is a common symptom associated with foreign body aspiration. In most cases, this is due to the foreign bodies lodging in the supraglottis, glottis, subglottis, or high extra‐thoracic trachea. Infrequently, foreign bodies located in the esophagus cause stridor. The ingestion of button batteries (BBs) has been reported to cause multiple probl...
Article
Objective To assess the effect on hearing of non-functioning ventilation tubes due to blockage during the first six months post-operatively, using UK national guidelines. Method A prospective, observational study was conducted on 37 children who underwent bilateral ventilation tube insertion. Air and bone conduction thresholds were measured before...
Article
Objectives: Primary: to compare, in vitro, the antimicrobial activity of different antiseptic agents versus quinolone drops, against the common organisms of chronic otitis media.Secondary: to examine the possible role of pH on the antimicrobial activity of the antiseptic solutions. Methods: Three antiseptic powders (boric acid; iodine; and a 1:1...
Article
Surgery for cholesteatoma of the facial recess and sinus tympani: retrotympanotomy from anterior, mobilizing and using chorda tympani for guidance - Farrior's principle rediscovered and modified - Volume 130 Issue S3 - James Loock
Article
Cholesteatoma: How it grows and where it goes, and how we should therefore approach its surgery: An analysis of data collected prospectively on 516 cases. - Volume 130 Issue S3 - James Loock
Article
Full-text available
Foreign bodies are potentially life-threatening when inhaled by a child, depending on where they lodge. Symptoms can range from acute upper airway obstruction to mild, vague respiratory complaints. Between 80% and 90% of inhaled foreign bodies occlude the bronchi, while the larynx is a less common site. The commonest inhaled paediatric foreign bodi...
Article
Background: The aim of this study was to evaluate the effectiveness of liquid-based transepithelial flexible brush cytology (LBTFBC) in the detection of high-grade laryngeal mucosal lesions. Methods: Diagnostic accuracies of LBTFBC and flexible biopsy (FB) were compared with the gold standard of biopsy under general anaesthesia (BUA) in 49 and 4...
Article
Background: Wegener's granulomatosis is generally a chronic, indolent, inflammatory condition, treated with cytotoxics (cyclophosphamide) and corticosteroids. Objective: This paper reports an unusual case of acute fulminant Wegener's granulomatosis that failed to respond to conventional treatment, but showed a dramatic response to rituximab, whi...
Article
Full-text available
Primary: to compare one-off administration of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating active chronic otitis media. Secondary: to evaluate the effectiveness of Quadriderm® cream in resistant active chronic otitis media; and to document side effects of these treatments, especially hearing loss. Randomis...
Article
To investigate the incidence of metastasis to the submandibular gland in patients with head and neck squamous cell carcinoma. We retrospectively evaluated histological reports of neck dissections for upper respiratory tract carcinoma (performed 2002-2009), recording: primary tumour site, tumour-node-metastasis stage, level Ib involvement, previous...
Article
1. To determine the consequences of prolonged intubation on laryngeal function. 2. To evaluate simple clinical criteria or tests that could alert the clinician to potential laryngeal pathology requiring ear, nose, and throat/otolaryngology (ENT) referral. A prospective case series. A surgical intensive care unit in a tertiary academic hospital in C...
Article
We present a case report and review the world literature concerning otosyphilis, particularly with reference to the HIV positive patient. Our patient received two separate courses of treatment for otosyphilis. A course of intramuscular penicillin and oral prednisone resulted in no improvement in his hearing thresholds. A subsequent course of intrav...
Article
Full-text available
Axillary nodal metastasis is very rare in head and neck squamous cell carcinoma. The few cases reported in the literature all involve patients who have previously undergone either neck dissection alone, or neck dissection and radiotherapy to the neck, and subsequently develop delayed recurrences of disease, with axillary nodal involvement. We prese...
Article
To investigate missed appointments in a South African tertiary hospital. Prospective, descriptive series with controls. The ENT/Oncology clinic at Tygerberg Academic Hospital, South Africa. Subject: 305 patients with a head and neck malignancy who had follow-up appointments over 4 consecutive months between June and September 2006. A control group...
Article
To determine whether the way in which temporalis fascia is treated during myringoplasty affects the rate of successful perforation closure. A randomised controlled trial. A tertiary ENT Department within the Tygerberg Academic Hospital. One hundred and fifty patients with perforations between 30% and 70% of the surface area of the eardrum undergoin...
Article
The aim of this study was to determine an accurate indicator of the need for second aspiration of peritonsillar abscesses the day after initial aspiration. A tertiary otolaryngology care centre. Fifty patients aged between 11 and 49 years with suspected peritonsillar abscess. A prospective case series. The potential indicators investigated included...
Article
Emergency tracheostomy prior to laryngectomy for laryngeal carcinoma has been associated with peristomal recurrence. Is the peristomal recurrence caused by the tracheostomy per se, or is it due to the association of tracheostomy with subglottic tumours and locally advanced tumours? This study examines the association between tracheostomy, as an ind...

Network

Cited By