Jagat Ram

Jagat Ram
Postgraduate Institute of Medical Education and Research | PGIMER · Department of Ophthalmology

MBBS, MS, FAMS

About

458
Publications
71,314
Reads
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5,045
Citations
Citations since 2016
228 Research Items
2586 Citations
20162017201820192020202120220200400600
20162017201820192020202120220200400600
20162017201820192020202120220200400600
20162017201820192020202120220200400600
Additional affiliations
January 1999 - present
Postgraduate Institute of Medical Education and Research
Position
  • Post-graduate Medical Education and Research, Chandigarh
April 1998 - August 1998
Biomedical Informatics Centre
Position
  • Research Associate
January 1998 - December 2003
The Medical University of South Carolina
Education
July 1979 - June 1982
September 1973 - June 1978
Govt. Medical College, Shimla (HP), India
Field of study
  • Medicine

Publications

Publications (458)
Preprint
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Pseudoexfoliation syndrome (XFS) effects the intraocular pressure (IOP) and vision of eye by causing pseudoexfoliation glaucoma (XFG). miRNAs have previously been linked to the aetiology of XFS and XFG. Present study focuses on the differential expression pattern of microRNAs (miRNAs) in anterior lens capsule (ALC) of XFS and XFG. For this, RNA fro...
Article
The aim of this systematic review and meta-analysis was to summarize and compare the available evidence on the level of vitamin D and antioxidant trace elements between the keratoconus (KC) patients and healthy controls. Seven case-control studies with 830 subjects were found eligible with a systematic search using PubMed, SCOPUS, Web of Science, a...
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Long axial length is one of the ocular protective factors in development of diabetic retinopathy (DR). In this study we examined the effect of axial length (AL) on aqueous humor vascular endothelial growth factor (VEGF) levels in patients with diabetes mellitus with or without DR. Forty-eight eyes of 48 participants were divided into three groups o...
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Purpose: To evaluate the association of daily screen time and quality of sleep with the prevalence of dry eye among college-going women. Methods: This study was a cross-sectional, comparative questionnaire-based study of 547 college-going women in northern India. A 10-item Mini Sleep Questionnaire was used to check the quality of sleep, and the...
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Purpose: To analyze the impact of the pandemic on trends in cataract surgical volume in 2020 in a high-volume tertiary care academic center in North India. Methods: The monthly cataract surgical volume for a large, high-volume, tertiary care academic center in North India was obtained from January 2018 through December 2020. Based on historical...
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The major challenge these days in pediatric cataract surgery is not the technique of surgery or intraocular lens (IOL) used but the postoperative refractive error. Amblyopia occurring due to postoperative refractive error which the child has; destroys the benefit obtained by a near-perfect and timely surgery. Even if we settle the debate as to what...
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Purpose: Cataract and diabetes, both being a major health care problem, an intervention evaluated for the combination of the two attains paramount importance. The purpose of the study was to determine the role of intraoperative intravitreal dexamethasone implant in patients with diabetic retinopathy with/without macula edema undergoing phacoemulsi...
Preprint
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PURPOSE Long axial length is one of the ocular protective factors in development of diabetic retinopathy (DR). In this study we examined the effect of axial length (AL) on aqueous humor vascular endothelial growth factor (VEGF) levels in patients with diabetes mellitus with or without DR. METHODS Forty-eight eyes of 48 participants were divided in...
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Purpose: Coronavirus Disease 2019 (COVID-19) pandemic has negatively impacted medical professionals in all fields of medicine and surgery in their academic, clinical and surgical training. The impact of surgical training has been described as 'severe' by most ophthalmology residents worldwide due to their duties in COVID-19 wards, disruption of ou...
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Purpose: To present a case series of intumescent white cataract cases managed by a new surgical technique to attain a single stage Continuous Curvilinear Capsulorhexis (CCC). Methods: The series included 60 eyes of 60 patients with white cataract which underwent preoperative anterior chamber depth, lens thickness and ultrasonographic A-scan for...
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We describe a novel device, Jagat and Bala Intraocular lens Supporting System (JBISS), an artificial Intraocular lens (IOL) platform that facilitates IOL fixation in an aphakic patient with poor capsular support and also facilitates IOL exchange in case of myopic shift or refractive surprise. Implantation of JBISS along with IOL was carried out in...
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Abstract Introduction Rubella is an important infectious, vaccine-preventable etiology of congenital defects. The aim of the study was to develop a prediction nomogram to assess the probability of an infant being at risk for congenital rubella based on demographics and ophthalmological findings. Methods This was a cross-sectional sentinel surveilla...
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Purpose: To discuss the impact of COVID-19 pandemic on the pediatric cataract surgery services in a tertiary care institute in India, as well as the protocol followed for these surgeries. Methods: COVID-19 has hampered outpatient and elective services and surgeries throughout the world. During the national lockdown imposed in March in India, out...
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Purpose To assess the efficacy and safety of intracameral mydriatic and anesthetic combination for pupillary dilation in pediatric cataract surgery Methods This prospective series included children <12 years, with visually significant unilateral or bilateral cataracts planned for cataract surgery with/without intraocular lens implantation. At the...
Article
Purpose: To compare the efficacy of 2% rebamipide suspension with topical cyclosporine and tacrolimus for managing vernal keratoconjunctivitis (VKC) Methods: In this prospective, interventional study, 38 patients with moderate to severe VKC were allocated to receive either 2% rebamipide in one eye and 0.03% tacrolimus ointment in the contralateral...
Preprint
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Objectives. To summarize abrupt eccentric eye positioning in downgaze following the downward movement of eyes encountered in patients undergoing ophthalmic surgeries under general anesthesia (GA) and analyze the relationship between the fluctuation in the depth of anesthesia (DOA) and eccentric eye positioning in downgaze. Subjects and Methods. Pat...
Preprint
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Purpose: To describe and analyze the relationship between the downward eccentric eye movement/positioning encountered in patients undergoing ophthalmic surgeries under general anesthesia (GA) with fluctuation in the depth of anesthesia (DOA) Design: observational case-series Methods. Patients undergoing ophthalmic surgeries under GA without non-de...
Preprint
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Background. Unexpected tonic down-rolling and eccentric down-positioning of eyes during general anesthesia can have serious implications in ocular surgeries. Objectives. To summarize abrupt eccentric eye positioning in downgaze following the downward movement of eyes encountered in patients undergoing ophthalmic surgeries under general anesthesia (...
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Objectives Healthcare personnel (HCP) are at an increased risk of acquiring COVID-19 infection especially in resource-restricted healthcare settings, and return to homes unfit for self-isolation, making them apprehensive about COVID-19 duty and transmission risk to their families. We aimed at implementing a novel multidimensional HCP-centric eviden...
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PurposeTo study the complications and surgical outcomes of cataract surgery in patients of persistent fetal vasculature (PFV) with cataract.Methods In this prospective study, phacoaspiration with/without intraocular lens implantation (IOL) was done in 20 children (mean age 14.2 months) with unilateral cataract with anterior (n = 6) or combined (n =...
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Objective To elucidate disease-specific host protein profile in vitreous fluid of patients with intraocular inflammation due to tubercular uveitis (TBU). Methods Vitreous samples from 13 patients with TBU (group A), 7 with non-TBU (group B) and 9 with no uveitis (group C) were analysed by shotgun proteomics using Liquid Chromatography Tandem Mass...
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A 13‑year‑old healthy female presented with a bilateral blurring of vision. Her best‑corrected visual acuity was 20/60 OU. Slit‑lamp examination revealed bilateral, central lamellar lenticular opacity with “Y”‑shaped stellate opacities along anterior and posterior sutural lines. Also, there were multiple blue cortical opacities OU. Family history w...
Article
High anisotropy in thermal conductivity (κ) coupled with anisotropy in Seebeck coefficient (S) has resulted in peak zT value of 0.85 at 150 °C in the textured Sb1.5Bi0.5Te3 nanomaterial in perpendicular to the preferential ab-plane direction. Further, strong and opposite temperature dependences in electrical conductivity (σ) and thermal conductivit...
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Purpose: To evaluate the potential causes of postoperative complications and the visual outcome after surgery for age-related cataract in dry eyes. Setting: Tertiary-care multidisciplinary referral medical institution. Methods: The records of 15 patients (21 eyes) with age-related cataract, a Schirmer value of 5.0 mm or less in 5 minutes, and a tea...
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Background and Aims: Literature documents EC50(End-tidal) of sevoflurane for CLMA (Classic Laryngeal Mask airway) insertion between 1.5 and 2% and most of these studies suggest maintaining the required end-tidal sevoflurane concentration for 10-25 minutes before LMA insertion. Waiting for this long interval for blood brain sevoflurane equilibration...
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A 38-year-old farmer presented to the emergency with a 2-day history of foreign body sensation and discharge in his left eye after manure fell into his eye. His visual acuity was 20/20. On examination, lids were edematous, conjunctiva congested, and cornea was clear. A maggot was seen on the upper palpebral conjunctiva [Figure 1a], which was remove...
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Purpose To evaluate safety and efficacy of topical cysteamine ophthalmic solution for corneal cystinosis. Method We searched seven databases(PubMed, OVID, EMBASE, Web of Science, Cochrane CENTRAL, Google scholar and ClinicalTrials.gov) for relevant studies using appropriate keywords. Comparative observational studies/ RCTs comparing cysteamine wit...
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Abstract We compared the results of strabismus surgery using adjustable and nonadjustable hang-back muscle recessions in 38 patients having concomitant exotropia. The two groups were matched for age of the patient, type of concomitant exotropia, amount of deviation, and type and amount of muscle surgery. At 6 months follow-up, 18 of the 19 patients...
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PURPOSE: To evaluate the efficacy of frequency-doubled Nd:YAG (532 nm) laser treatment in quiescent corneal vascularisation, and to record the sequential changes in lasered vessels and complications in eyes with one and two quadrant vascularisation. METHODS: Thirty eyes (30 patients)-15 eyes (15 patients) with one-quadrant and 15 eyes (15 patients)...
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Scleral involvement in association with en-dophthalmitis is unusual. We report a case of recurrent bacterial endophthalmitis and mulitple scleral abscesses occurring 8 months following cataract extraction. Culture of pus from scleral abscesses first grew Pseudomonas aeruginosa; and klebsiella pneumoniae on recurrence. The patient responded to inten...
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A two-year-old female child presented with a left retinal mass in front of the optic disc and total serous retinal detachment. Enucleation was performed for suspected retinoblastoma. Histopathologically the tumour was composed of astrocytic giant cells with a few spindle-shaped astrocytes. Presence of multiple necrotic foci in the tumour resembling...
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Background Toxic epidermal necrolysis (TEN) is a life‐threatening severe cutaneous adverse reaction. Data on pediatric TEN is limited. Methods Case records of 44 children, 1 month–12 years with a diagnosis of TEN (>30% body surface area [%BSA] detachment) admitted to a tertiary pediatric intensive care unit (PICU) between 2009 and 2018 were analyz...
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Cataract is the second leading cause of preventable blindness on the globe. Several programs across the country have been running efficiently to increase the cataract surgical rates and decrease blindness due to cataract. The current COVID-19 pandemic has led to a complete halt of these programs and thus accumulating all the elective cataract proce...
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A 25-year-old man, with a history of hyperthyroidism presented with herpes zoster ophthalmicus (HZO) with neurotrophic ulcer and superadded infection 4 weeks after a sudden decrease in his thyroid hormones, caused by overtreatment of hyperthyroidism and radioactive iodine therapy. He underwent lateral tarsorrhaphy and was started on conservative tr...
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An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Eye care professionals are susceptible to contract COVID-19 infection due to the presence of the virus in tears and conjunctival secretions and, also, partly due to the proximity required during ophthalmic examination. Although infrequent, ocular features include conjunctivitis (predominant), chemosis, follicles, itching, dry eye, and tearing. In t...
Article
Coronavirus disease 2019 (COVID-19) is caused by a highly contagious RNA virus termed as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Ophthalmologists are at high-risk due to their proximity and short working distance at the time of slit-lamp examination. Eye care professionals can be caught unaware because conjunctivitis may be on...
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We describe a novel technique "alternate iris bypass technique" of iridodialysis repair in four patients experiencing traumatic iridodialysis along with cataract. In these cases, we have combined iridodialysis repair with phacoemulsification and intraocular lens implantation. The main advantage of this technique is that edges of the iridodialysis c...
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The COVID-19 pandemic has taken tragic proportions and has disrupted lives globally. In the wake of governmental lockdowns, ophthalmologists need practical and actionable guidelines based on advisories from national health departments on how to conduct their duties during nationwide lockdowns and after these are lifted. In this paper, we present a...
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This is a Photo Essay and does not have an abstract.
Article
Objective (1) To report the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy rate (%) of eight rigid and foldable intraocular lens (IOL) designs in a series of 5416 pseudophakic human eyes obtained postmortem, accessioned in our center between January 1988 and January 2000. (2) To identify factors that are instrumental in redu...
Article
Phacolytic glaucoma is one of the varieties of various lens induced glaucoma, also known as lens protein glaucoma is a sequelae of hypermature cataract. In our case 60 years old male presented with lid edema, pain, redness, loss of vision of right eye with exudates or fluffy deposits in the anterior chamber mimicking endophthalmitis. Endophthalmiti...
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Background: Primary objective of this review was to measure compliance with spectacle use in children with refractive errors. Secondary objective was to understand the reasons for non-compliance. Methods: The databases searched were Ovid, EMBASE, CINAHL and Pubmed. All studies up to March, 2018 were included. The search terms were- ((((((Complia...
Preprint
Full-text available
Background Primary objective of this review was to measure compliance with spectacle use in children with refractive errors. Secondary objective was to understand the reasons for non-compliance.Methods The databases searched were Ovid, EMBASE, CINAHL and Pubmed. All studies up to March, 2018 were included. The search terms were- ((((((Compliance [T...
Article
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Background Government of India is committed to eliminate measles and control rubella/congenital rubella syndrome (CRS) by 2020. In 2016, CRS surveillance was established in five sentinel sites. We analyzed surveillance data to describe the epidemiology of CRS in India. Methodology/Principal findings We used case definitions adapted from the WHO-re...
Preprint
Full-text available
Background Primary objective of this review was to measure compliance with spectacle use in children with refractive errors. Secondary objective was to understand the reasons for non-compliance. Methods The databases searched were Ovid, EMBASE, CINAHL and Pubmed. All studies up to March, 2018 were included. The search terms were- ((((((Compliance [...