Jagadish C Das

Chittagong Medical College · Neonatology & Pediatrics

Human milk oligosaccharides (HMOs) constitute a significant and intriguing component of human milk, ranking as the third most abundant solid constituent following lactose and lipids.Meanwhile, gut microbiota encompasses an array of microorganisms,spanning bacteria, archaea, fungi, and viruses, residing within the digestive tract. The intricate inte...

In pediatric patients, Coronavirus disease-19 (COVID-19) presents usually without symptoms or with mild to moderate COVID-19. However, infants may present with more severe diseases, leading to even respiratory failure. COVID-19 may adversely affect the course of congenital heart disease (CHD) and vice versa in neonates and small infants. There is l...

Introduction: Discharge against medical advice (DAMA) is an unexpected event for patients and healthcare personnel. The study aimed to assess the prevalence of DAMA in neonates along with characteristics of neonates who got DAMA and, causes and predictors of DAMA. Methods and findings: This case-control study was carried out in Special Care Newbor...

Rights are basic standards which people demands for their self-development and without which people cannot live in dignity. The United Nations Universal Declaration of Human Rights (UDHR,1948) tells, “all human beings are born free and equal in dignity and rights without any discrimination”. Human Rights are mostly inherent and natural. These right...

Background: Neonates with Perinatal Asphyxia(PNA) are at the higher risk for developing Acute Kidney Injury(AKI). Conventionally, serum creatinine (sCr) is used to diagnose AKI but lacks specificity during the first few days of life. Neutrophil Gelatinase- Associated Lipocalin (NGAL) has emerged as a novel biomarker of AKI in such situations,while...

Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China in December 2019 and now has led to a global pandemic. The incidence is lower in neonates. A five days old newborn infant got admitted with history of reluctance to feeding and less movement. On admission, the newborn infant was f...

Hyperpigmentation as primary symptom is rare in vitamin B12 deficiency. This adolescent non vegetarian girl presented with hyperpigmentation, anaemia, glossitis and weight loss. She was worked up to find out the cause of anemia and hyperpigmentation. Addison disease was a strong provisional diagnosis. Her cortisol level was normal and megaloblastic...

In Bangladesh, SDG target for neonatal mortality is 12 per 1000 live births.Emphasis is being given on neonatal service at community as well as in facility level. Development of SCANU and NICU is emphasized. an NICU is a specialized center for ill or premature newborn infants, typically directed by a neonatologist and staffed by nurses,resident phy...

Food is essential for growth and development. Food that can be served ready to eat fast is termed fast food. Junk food and fast food are often used interchangeably. Energy dense food with high sugar,fat or salt content and low nutrient value in terms of protein, fiber, vitamin and mineral is junk food. Many children are fond of such food. Sponsorsh...

Breast feeding is the best form of infant feeding. Percentage of taking antibiotics in lactating mother is not much high in developed nation but it is quite high in developing nation specially in case of hospital delivery. Generally breast milk does not adversely affect the infant of lactating mother taking majority of antibiotics. But sometimes un...

Eventration of diaphragm is an abnormal elevation of diaphragmatic musculature while retaining normal attachments to the sternum, ribs and dorsolumber spine. It is a rare anomaly where the continuity of diaphragm remains intact. Pathological process can affect either all or only a portion of hemidiaphragm. Symptoms vary according to size of the def...

Use of drug in pediatrics and neonatology should be rational. There are clinical situations when the use of unlicensed medicines or use of medicines outside the terms of license (i.e., ‘off-label’) may be judged by prescriber in the best interest of the patient. Off-label prescribing is clinically appropriate when the benefits outweigh the potentia...

Organophosphorus compounds (OPC) are widely used insecticides. Such poisoning is very rare in neonate. A 23 days old infant was admitted with severe respiratory distress, excessive secretion from nose and mouth, bluish discoloration of extremities and poor feeding for 4 hours. He was pale, cyanosed and lethargic with gasping respiration. Frothing w...

Use of drug in pediatrics and neonatology should be rational. There are clinical situations when the use of unlicensed medicines or use of medicines outside the terms of license (i.e., 'off-label') may be judged by prescriber in the best interest of the patient. Off-label prescribing is clinically appropriate when the benefits outweigh the potentia...

Preface of the 2nd Edition WHO, in the post-2015 strategy for tuberculosis, envisioned zero deaths, suffering and diseases by TB. Mllestones were set to achieve 75% and 90% reduction of death, in comparison to deaths in 2015, by 2025 and 2035 respectively. Furthermore, targets have been set to reduce cases to 55 per 100,000 by 2025, and to 10 per 1...

Background: Hypernatremic dehydration is a lethal condition in neonate which adversely affects central nervous system. Important causes of this condition in neonate are vomiting, diarrhea, improper preparation of infant formula, inadequate breast feeding and diabetes insipidus. Hypernatremic dehydration presents usually around tenth postnatal day....

Abstract: Background: Birth weight is an important indicator of neonatal health. Incidence of low birth weight infants in developing country like Bangladesh is high. Deliveries as 75% are conducted in rural community mainly by Traditional Birth Attendants or by relatives. Facility of birth weight recording is not existent. To overcome the problem o...

p>Abstract not available Bangladesh J Child Health 2015; VOL 39 (1) :46-49</p

Fast food refers to food that can be served ready to eat fast. Fast food and junk food are often used interchangeably. Energy dense food with high sugar/fat/salt content and low nutrient value in terms of protein, fiber, vitamin and mineral content is termed junk food. Many of our children are fond of such readymade food. Sponsorship of sports or c...

Electroencephalogram (EEG) has an important role in the management of seizure disorder in children. It helps in diagnosis and classification of epilepsy, choosing of antiepileptic medication and prediction of prognosis. When history of epilepsy is unclear, EEG can help to distinguish epileptiform discharges from its counterpart. But EEG has limitat...

Neonatal period is the most susceptible period of life due to different diseases, which in most cases are preventable. Patient's load of newborn infants in a tertiary hospital is not less. Was to see the frequency and pattern of neonatal morbidity and mortality in Chittagong Medical College Hospital. A retrospective clinical audit was conducted at...

Childhood renal diseases are increasing in Bangladesh. It is necessary to monitor the nature of these diseases in each locality for effective health care planning. Our aim was to identify the pattern and etiology of kidney disease in children living in Chittagong division. We reviewed the documents of all children presented with renal diseases betw...

Neonatal septicemia is a clinical syndrome of systemic illness accompanied by bacteremia occurring in the first 28 days of life. It may occur through transplacental infection or an ascending infection from mother's genitor-urinary tract and from the infected caregiver or nosocomial infection. Micro-organism causing neonatal septicemia varies from c...

Congenital adrenal hyperplasia (CAH) is a rare condition with different presentations. The most important 'salt loosing' variant is a medical emergency. More than 90% of cases of congenital adrenal hyperplasia are caused by 21 a-hydroxylase deficiency (21aOH). Rather than cortisol, the adrenals produce excess sex hormone. Majority of patients canno...

When supplementation of oxygen is inappropriate there is chance of development of either hypoxia or hyperoxia. During oxygen therapy, oxygen level should be maintained within a target-able range through proper monitoring. Pulse oximetry is a useful convenient and reliable monitoring system. The principle of working of pulse oximeter is based on the...

Bangladesh is a densely populated developing country. Majority of the population live here in the rural community. Illiteracy,poverty and malnutrition are widely prevalent here. Health service facilities even for the neonate are not satisfactory. Anthropometric parameters at birth are considered to be of grate value.Incidence of low birth weight is...

Key words: Oxygen saturation; monitoring; neonateDOI: 10.3329/jcmcta.v21i2.7735 Journal of Chittagong Medical College Teachers' Association 2010: 21(2):30-34

Measurement of blood pressure properly is important.Prevalence of hypertension in children is not less.Morbidity and mortality of hypertension cannot be ignored.Blood pressure(BP) should be measured systematically among children over 3 years old who are seen in a medical setting.Among <3 years children, blood pressure should be measured in special...

Assessment of fluid and electrolyte properly in neonate is very important but difficult. Fluid and electrolyte homeostasis during this period depends on some factors notably gestational age of baby, its postnatal age, pathological conditions and environmental situation. In fetus, water and electrolytes is constantly supplied from mother, which is c...

Key words: enteric fever; investigation; children; blood culture; Widal Testdoi: 10.3329/jcmcta.v18i2.3835Journal of Chittagong Medical College Teachers' Association 2007: 18(2):37-42

Key words: socio-biological factors; parity; pregnancy duration; spacing; association; birth weight doi: 10.3329/jcmcta.v19i1.3851 Journal of Chittagong Medical College Teachers' Association 2008: 19(1):37-42

Prevalence of hypertension in children is diffuse in west less well known in our set up. Hypertension is defined as average systolic blood pressure and/or diastolic blood pressure that is ≥95th percentile for age, gender and height on ≥3 occasions. It may be described as primary (essential) or secondary due to a definable cause. Renal parenchymal d...

Fluid and electrolyte management in neonate is very important. Fluid and electrolyte homeostasis during this period occur from discontinuation of placental exchange,onset of insensible water loss, thermoregulation, renal regulation of fluid- electrolytes and intake of fluids and other nutrients. The adaptation course is divided into transition phas...

Assessment of fluid and electrolyte properly in neonate is very important but difficult.Fluid and electrolyte homeostasis during this period depends on some factors notably gestational age of baby,its postnatal age,pathological conditions and environmental situation. In fetus,water and electrolytes is constantly supplied from mother,which is cut-of...

Prevalence of hypertension in children is not less at all. Morbidity and mortality of hypertension cannot be ignored.Blood pressure(BP) should be measured to all children of >3 years old who are seen in a medical setting.In children <3 years old,blood pressure should be measured in special circumstances.There are various methods of recording bolld...

Helicobacter pylori is one of the commonest bacterial pathogens in human. The organism is associated with development of peptic ulcer diseases, lymphoproliferative disorders and gastric cancer. Residence in a developing country, poor socio-economic conditions and genetic predisposition are regarded as risk factors. Prevalence of infection is higher...

Newborn baby has limited reserve of vitamin K at birth.Failure of vitamin K prophylaxis may lead to unexpected bleeding during first week, known as early vitamin K deficiency bleeding (VKDB) or even during second to twelfth week of life, known as late VKDB. Certain drugs taken by mother during pregnancy, low vitamin K content in breast mink, late s...

Helicobacter pylori is a small, highly motile, gramnegative bacillus. It is one of the commonest bacterial pathogen in human being.Helicobacter pylori infection is mainly acquired in childhood. How infection transmits till not clearly understood. Person-to-person transmission seems to be most likely mode of transmission. Transmission of infection f...

Introduction Helicobacter pylori is a small, highly motile, gram-negative bacillus. It is one of the commonest bacterial pathogen in human being 1. There is a causal relationship of this small spiral organism to gastritis, peptic ulcer, lymphoproliterative disorder and gastric cancer 2-5. H. pylori infects at least 50% of world's human population 5...

Birth weight is a reliable and sensitive indicator for predicting the immediate or later outcome of a newborn child. In a developing country like Bangladesh, where more than 75% of deliveries occur in rural community and are mostly attended by Traditional Birth Attendants (TBA) or relatives, birth weight cannot be recorded mainly due to paucity of...

Helicobacter pylori infection is one of the most common chronic bacterial infections in human.In developing countries about 80% peoples are infected by adolescence.Interaction between host,environment and H.pylori in the development of peptic ulcer diseases have been proposed.There is no specific clinical features of findings in children but some g...

Lead poisoning is one of the emerging health problems in Dhaka city.The concentration of lead here is several times higher than the safe concentration of less than 100ng/l. The major sources of exposure are lead containing paints,dusts,leaded water pipes,fumes from burning batteries,gasoline,waste oil combustion.The high density traffic with leaded...

Arsenic in ground water of Bangladesh is considered to be the biggest arsenic calamity in the world.Arsenic constantly changes its nature in air,soil and water.Aetiology of arsenic pollution in Bangladesh are geohydrological aspect of Bangladesh,situation of Bangladesh,exploitation of nature,geothermal power plant,use of fertilizer and dumping chem...

Introduction Oxygen is the most common drug used in neonatology worldwide 1. Inappropriate supplementation of oxygen may not decrease hypoxia or may lead to development of hyperoxia. Hypoxia may lead to pulmonary vasoconstriction, pulmonary hypertension, neurological and other organ damage 2. This condition may be associated with lethargy, cyanosis...

This cross-sectional study was designed to assess the influence of the nutritional status of the mother upon the anthropometric measures of their babies. It was conducted at three different hospitals of Dhaka city during a short period of 5 weeks in 1992. One hundred and fifty mothers with their newborns were studied to correlate their anthropometr...

A study was conducted in Dhaka city in 1992.One hundred and fifty mothers with their newborns were studied to observe some maternal biological determinants of birth weight. Maternal age, parity, duration of pregnancy, birth spacing, weight, height (length), mid-arm circumference were considered.The study showed that the relationship between weight...

One hundred and thirty one victims of non poisonous snake bite were treated in Chittagong The victims were mostly young male. The bite happened mostly in day time (61%) and the patients were admitted within nine hours of bite. Site of the bite was mostly in lower limb and at least 3 tomiquet were applied in a tight fashion. The non poisonous snake...

Eclampsia is the term used to describe a syndrome complex associated with pregnancy that may occur before,during or after labour.Incidence of eclampsia at Dhaka Medical Hospital in 1989-1990 was 8.34% among total hospital deliveries.Predisposing factors for this condition exist in majority of Bangladeshi mothers. Most of the eclamptic mothers pass...