Jadoon Khan

• Ph.D Microbiology
• Professor (Assistant) HoD at Sarhad University of Science & IT Islamabad

Brucellosis is a zoonotic disease of global public health concern, with significant impacts on both humans and animals. This study aimed to determine the seroprevalence of brucellosis in human and animal blood samples, while also identifying key risk factors associated with its transmission. A total of n = 1219 blood samples including 250 from huma...

Various metabolic and cell signaling processes impact the functions of sugarcane plant cells. MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. This study seeks to identify and partially characterize several novel miRNAs in sugarcane using in silico tools, while also offering a...

Cartilage deterioration in patients with osteoarthritis presents a significant challenge, primarily attributable to the inadequate oral bioavailability and poor dosage compliance of chondroprotective agents. The Chondroitin Sulphate (CS) is a stabilizing and reducing agent for metal NP as well as homing agent by binding to surface molecules (CD44,...

Cystic echinococcosis (CE) is a worldwide zoonotic public health issue. The reasons for this include a lack of specific therapy options, increasing antiparasitic drug resistance, a lack of control strategies, and the absence of an approved vaccine. The aim of the current study is to develop a multiepitope vaccine against CE by in-silico identificat...

Background: Dengue is a widely spread mosquitoes transmitted viral infection pose a serious public health concern. The causative agent of dengue fever-dengue virus (DENV) belong to family flaviviridae consist of various four serotypes (DENV-1-4). Aims: The current study aimed at molecular characterization, clinical features, and dengue virus seroty...

Cystic echinococcosis (CE) is a neglected tropical zoonotic disease mostly prevalent in tropical and subtropical region of the world. The diagnosis of the disease is difficult and expensive and could not differentiate in current and past infection with higher cross reactivity. Hydated cyst fluid is a mixture of various excretory and secretory antig...

Introduction: Hepatitis C Virus is a highly infectious and potentially fatal ailment resulting in liver damage and inflammation, can be treated by anti-HCV medications. Latest updates in the development of anti-HCV medications are required for robust clinical decisions. Objective: To provide an overview of the most recent advancements in the pharma...

Seaweed has a huge potential as an alternative source for high-quality and healthier food products that have inspired researchers in the last few years. Despite considerable progress in medical therapy, there is no satisfactory drug to permanently treat kidney stones. Therefore, in the current study, the effects of oral administration of hydroalcoh...

Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2) is pneumonia like viral disease which was originated from Wuhan China in 2019. Besides its high morbidity and mortality, a lot of physiological, enzymatic, hormonal and genetic imbalances had also been observed among Corona Virus Disease-19 (COVID-19) patients. The purpose of the present...

Rotavirus A (RVA) is a leading cause of severe gastroenteritis in children worldwide, and vaccination has become a pivotal strategy to reduce the associated morbidity and mortality. This study presents a molecular characterization of RVA genotypes circulating among vaccinated children in Pakistan during the year 2019. A total of 510 stool samples w...

The crane is a large, beautiful animal with long necks, legs, and life expectancy. Like a few other wild wildlife, this group of birds has the potential to lift people's emotions. The current study was carried out from September 2019 to June 2022 in District Bannu Khyber Pakhtunkhwa, Pakistan to check the hunting rate of Demoiselle crane. Different...

Hepatocellular carcinoma (HCC) stands as the most common cancer type, arising from various causes, and responsible for a substantial number of cancer-related fatalities. Recent advancements in viral metagenomics have empowered scientists to delve into the intricate diversity of the virosphere, viral evolution, interactions between viruses and their...

Background and Aim Dengue infection is a global issue which is caused by insect transmitted, positive sense single-stranded RNA dengue virus (DENV). Around 50 million cases of dengue infection is being reported per year whereas population at risk of dengue of infection reaches about 2.5 billion in the tropical and subtropical regions of the world....

Rotavirus (RV) causes the loss of numerous children’s lives worldwide each year, and this burden is particularly heavy in low- and lower-middle-income countries where access to healthcare is limited. RV epidemiology exhibits a diverse range of genotypes, which can vary in prevalence and impact across different regions. The human genotypes that are...

Introduction Echinococcosis is a neglected tropical zoonotic infection that affects both the human and livestock populations. In Pakistan, the infection is long-standing, but data on its molecular epidemiology and genotypic characterization in the southern Punjab region are limited. The aim of the current study was the molecular characterization of...

Coronavirus disease 19 (COVID-19) is caused by viral infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Where upregulation of several important biomarkers and multiple organ dysfunction occurs, this study aimed to evaluate the association of cardiac biomarkers and CS induced acute lung damage with disease severity and mortal...

Celiac disease (CD) is a chronic inflammatory disorder in the intestinal tract as a response to the use of gluten in genetically predisposed individuals. It is a worldwide problem, with a high prevalence rate in North America. This is a descriptive cross-sectional study involving 1090 samples collected from different hospitals of Rawalpindi and Isl...

Objective: Rotavirus A (RVA) is a significant cause of severe diarrheal illness and one of the common causes of death in children under the age of five. This study was aimed at detecting the prevalence of RVA in Pakistan after rotavirus vaccines were introduced. Fecal samples were obtained from 813 children from different hospitals in Rawalpindi an...

ABSTRACTObjective:We aimed to investigate the genetic diversity of echinococcus granulosus using a modified Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) based assay in the infected population.Materials and methods A total of 18 human hydatid cyst samples were collected from various hospitals of Southern Punjab and I...

Cystic echinococcosis (CE) is a neglected zoonotic disease prevalent in Pakistan, but the genetic diversity of the cestode is largely unexplored in the country. This study investigated the molecular epidemiology of CE infecting the livestock population of the Malakand division, Khyber Pakhtunkhwa, Pakistan. A total of 1,200 livestock, including buf...

Group A rotaviruses (RVAs) are the leading cause of gastroenteritis, causing 0.2 million deaths and several million hospitalisations globally each year. Four rotavirus vaccines (RotarixTM, RotaTeqTM, Rotavac® and ROTASIIL®) have been pre-qualified by the World Health Organization (WHO), but the two newly pre-qualified vaccines (Rotavac® and ROTASII...

Objective Rotavirus A (RVA) is a significant cause of severe diarrheal illness and one of the common causes of death in children under the age of five. This study was aimed at detecting the prevalence of RVA in Pakistan after rotavirus vaccines were introduced. Fecal samples were obtained from 813 children from different hospitals in Rawalpindi and...

Background Nosocomial infections are a global health problem, affecting 1.4 million people in treatment centers, responsible for 80,000 estimated annual deaths. The current study aimed to assess the factor influencing nosocomial infections and to choose the best antibiotic for its treatment through culture analysis.MethodologyThe current study was...

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a major concern in many parts of the world, including Pakistan. The aim of this study was to investigate the prevalence of MRSA in slaughterhouses and meat shops in Rawalpindi-Islamabad, Pakistan, 2018–2019. A total of 300 samples were collected: 40 from each of working a...

Electronic waste (e-waste) is one of the growing issues globally. Various components of e-waste including lead, nickel, cadmium, aluminum, and various hazardous gases releasing from the burning of these materials are responsible for various health issues, especially for the impairment of immune system in preschool children. In this chapter, we repo...