
Jacqueline IkeMeharry Medical College
Jacqueline Ike
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12
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Publications (12)
Cases for a disease can be defined broadly using diagnostic codes, or narrowly using gold-standard confirmation that often is not available in large administrative datasets. These different definitions can have significant impacts on the results and conclusions of studies. We conducted this study to assess how using melanoma phecodes versus histolo...
Voriconazole exposure is associated with skin cancer, but it is unknown how the full spectrum of its metabolizer phenotypes impacts this association. We conducted a retrospective cohort study to determine how variation in metabolism of voriconazole as measured by metabolizer status of CYP2C19 is associated with the total number of skin cancers a pa...
Importance: Many patients will develop more than one skin cancer, however most research to date has examined only case status.
Objective: Describe the frequency and timing of the treatment of multiple skin cancers in individual patients over time
Design: Longitudinal claims and electronic health record-based cohort study
Setting: Vanderbilt Univers...
Tumor necrosis factor-alpha inhibitors (TNFi) can be an effective treatment for organ transplant recipients (OTR) with various diseases but can increase the risk of infection and drug interactions.¹ There is also a potential for acute graft rejection while on TNFi with an unclear causal relationship. Two patients experienced acute graft rejection o...
Voriconazole exposure is associated with skin cancer, but it is unknown how the full spectrum of its metabolizer phenotypes impacts this association. We conducted a retrospective cohort study to determine how variation in metabolism of voriconazole as measured by metabolizer status of CYP2C19 is associated with the total number of skin cancers a pa...
Purpose of Review
The purpose was to summarize the current role and state of artificial intelligence and machine learning in the diagnosis and management of melanoma.
Recent Findings
Deep learning algorithms can identify melanoma from clinical, dermoscopic, and whole slide pathology images with increasing accuracy. Efforts to provide more granular...
Dear Editor, Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder of the hair follicle. Previous studies show that International Classification of Diseases (ICD) codes can identify cases of HS with high positive predictive value (PPV).1–3 HS frequently has diagnostic delays of 5 years or more.⁴ We hypothesized that using ICD codes...